Andrograpanin (BioDeep_00000397301)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


4-[2-[(1R,4aS,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one

化学式: C20H30O3 (318.2195)
中文名称: 雄激素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1CC[C@H]2[C@@](C)(CCC[C@@]2(C)CO)[C@@H]1CCC1=CCOC1=O
InChI: InChI=1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1

描述信息

Andrograpanin is a natural product found in Andrographis paniculata, Potamogeton natans, and Andrographis affinis with data available.
Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2].
Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties[1][2].

同义名列表

10 个代谢物同义名

4-[2-[(1R,4aS,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl]-2H-furan-5-one; 2(5H)-Furanone, 3-(2-((1R,4aS,5R,8aS)-decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethyl)-; 3-[2-[(1R,4aS,5R,8aS)-Decahydro-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone; ANDROGRAPANIN (CONSTITUENT OF ANDROGRAPHIS) [DSC]; 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE; Andrograpanin, analytical standard; 3,14-Dideoxyandrographolide; UNII-89M92UDM18; Andrograpanin; 89M92UDM18



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

32 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Payal Srivastava, Anchal Garg, Rajesh Chandra Misra, Chandan Singh Chanotiya, Sumit Ghosh. UGT86C11 is a novel plant UDP-glycosyltransferase involved in labdane diterpene biosynthesis. The Journal of biological chemistry. 2021 09; 297(3):101045. doi: 10.1016/j.jbc.2021.101045. [PMID: 34363833]
  • Moumita Majumdar, Amit Dubey, Ritobrata Goswami, Tarun Kumar Misra, Dijendra Nath Roy. In vitro and in silico studies on the structural and biochemical insight of anti-biofilm activity of andrograpanin from Andrographis paniculata against Pseudomonas aeruginosa. World journal of microbiology & biotechnology. 2020 Aug; 36(10):143. doi: 10.1007/s11274-020-02919-x. [PMID: 32851551]
  • Satyanshu Kumar, Tushar Dhanani, Sonal Shah. Extraction of three bioactive diterpenoids from Andrographis paniculata: effect of the extraction techniques on extract composition and quantification of three andrographolides using high-performance liquid chromatography. Journal of chromatographic science. 2014 Oct; 52(9):1043-50. doi: 10.1093/chromsci/bmt157. [PMID: 24170124]
  • Jun Liu, Zheng-Tao Wang, Bao-Xue Ge. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. International immunopharmacology. 2008 Jul; 8(7):951-8. doi: 10.1016/j.intimp.2007.12.014. [PMID: 18486905]
  • Yun-Heng Shen, Rong-Tao Li, Wei-Lie Xiao, Gang Xu, Zhong-Wen Lin, Qin-Shi Zhao, Han-Dong Sun. ent-Labdane diterpenoids from Andrographis paniculata. Journal of natural products. 2006 Mar; 69(3):319-22. doi: 10.1021/np050160u. [PMID: 16562826]