Erythrosine (BioDeep_00000033647)

   

human metabolite Exogenous


代谢物信息卡片


3,6-Dihydroxy-2,4,5,7-tetraiodospiro[isobenzofuran-1(3H),9(9H)-xanthen]-3-one, 9ci

化学式: C20H8I4O5 (835.6550798)
中文名称: 四碘荧光素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)O)I)I)O)I
InChI: InChI=1S/C20H8I4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

描述信息

Erythrosine is a dye used in food and feed additives. Prohibited in U.S.A. and Norway Erythrosine is a cherry-pink synthetic fluorone food coloring. It is the disodium salt of 2,4,5,7-tetraiodofluorescein. Its maximum absorbance is at 530 nm in an aqueous solution, and it is subject to photodegradation.[citation needed]; It is used as a food coloring, in printing inks, as a biological stain, a dental plaque disclosing agent and a radiopaque medium. It is commonly used in sweets and foods marketed to children such as cake icing and cake-decorating gels. It is also used to color pistachio shells. While commonly used in most countries of the world, erythrosine is rarely used in the United States due to its known hazards, with Allura Red AC (Red #40) being generally used instead. However, Allura Red AC is banned in many European countries because it is an azo dye, despite the fact that it has fewer known health risks than Erythrosine
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins
Dye used in food and feed additives. Prohibited in U.S.A. and Norway [DFC]

同义名列表

32 个代谢物同义名

3,6-Dihydroxy-2,4,5,7-tetraiodospiro[isobenzofuran-1(3H),9(9H)-xanthen]-3-one, 9ci; 3,6-dihydroxy-2,4,5,7-tetraiodo-3H-spiro[2-benzofuran-1,9-xanthene]-3-one; 2, 4,5,7-Tetraiodofluorescein; 2,4,5,7-Tetraiodofluorescein; Cogilor orange 211.10; Erythrosine, phenolic; Cogilor orange 312.42; Tetraiodofluorescein; FD And C red no. 3; 2,4,5,7-Erythrosin; Aizen erythrosine; Erythrosine acid; C.I. FOOD red 14; C.I. acid red 51; Iodofluorescein; FOOD Red no. 3; Erythrosine b; FDC Red no. 3; F D And C #3; Erythrosin B; Dianthine b; Iodeosine b; Erythrosine; Pyrosine b; C.I. 45430; Erythrosin; Red 1427; Iodeosin; Felumin; Ceplac; Trace; e127



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Serap Çetinkaya, Volkan Eyupoglu, Halil İbrahim Çetintaş, Ali Fazıl Yenidünya, Özgür Kebabcı, Burak Tüzün. Removal of Erythrosine B dye from wastewater by Penicillium italicum: experimental, DFT, and molecular docking studies. Journal of biomolecular structure & dynamics. 2023; 41(23):14212-14223. doi: 10.1080/07391102.2023.2186704. [PMID: 36889933]
  • Luqing Li, Qingqing Cui, Menghui Li, Tiehan Li, Shuci Cao, Shuai Dong, Yujie Wang, Qianying Dai, Jingming Ning. Rapid detection of multiple colorant adulteration in Keemun black tea based on hemp spherical AgNPs-SERS. Food chemistry. 2023 Jan; 398(?):133841. doi: 10.1016/j.foodchem.2022.133841. [PMID: 35969993]
  • Bassam Shaaban Mohammed, Sayed M Derayea, Yasser F Hassan, Ahmed A Abu-Hassan. Resonance Rayleigh scattering approach based on association complex formation with erythrosine B for determination of venlafaxine, application to the dosage form and spiked human plasma. Luminescence : the journal of biological and chemical luminescence. 2022 Jul; 37(7):1215-1222. doi: 10.1002/bio.4290. [PMID: 35582967]
  • Yousef Rashtbari, Shirin Afshin, Asghar Hamzezadeh, Abdolmajid Gholizadeh, Farshid Jaberi Ansari, Yousef Poureshgh, Mehdi Fazlzadeh. Green synthesis of zinc oxide nanoparticles loaded on activated carbon prepared from walnut peel extract for the removal of Eosin Y and Erythrosine B dyes from aqueous solution: experimental approaches, kinetics models, and thermodynamic studies. Environmental science and pollution research international. 2022 Jan; 29(4):5194-5206. doi: 10.1007/s11356-021-16006-7. [PMID: 34417700]
  • Maria J Bistaffa, Sabrina A Camacho, Carlos F O R Melo, Rodrigo R Catharino, Karina A Toledo, Pedro H B Aoki. Plasma membrane permeabilization to explain erythrosine B phototoxicity on in vitro breast cancer cell models. Journal of photochemistry and photobiology. B, Biology. 2021 Oct; 223(?):112297. doi: 10.1016/j.jphotobiol.2021.112297. [PMID: 34482154]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Hesham Salem, Fatma A Abo Elsoud, Dina Heshmat, Ahmed Magdy. Resonance Rayleigh scattering technique-using erythrosine B, as novel spectrofluorimetric method for determination of anticancer agent nilotinib: Application for capsules and human plasma. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Apr; 251(?):119428. doi: 10.1016/j.saa.2021.119428. [PMID: 33485244]
  • Donay Yuvali, Müslüm Seyhaneyildizi, Mustafa Soylak, İbrahim Narin, Erkan Yilmaz. An environment-friendly and rapid liquid-liquid microextraction based on new synthesized hydrophobic deep eutectic solvent for separation and preconcentration of erythrosine (E127) in biological and pharmaceutical samples. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jan; 244(?):118842. doi: 10.1016/j.saa.2020.118842. [PMID: 32871393]
  • Wopara Iheanyichukwu, Adebayo O Adegoke, Olusegun G Adebayo, Modo Emmanuel U, Aziemeola Pius Egelege, Jeremiah T Gona, Fortune M Orluwene. Combine colorants of tartrazine and erythrosine induce kidney injury: involvement of TNF-α gene, caspase-9 and KIM-1 gene expression and kidney functions indices. Toxicology mechanisms and methods. 2021 Jan; 31(1):67-72. doi: 10.1080/15376516.2020.1828523. [PMID: 32981412]
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  • Jidong Yang, Ernv Wang, Shang Zhou, Qiong Yang. Effects of (R)- and (S)-propranolol hydrochloride enantiomers on the resonance Rayleigh scattering spectra with erythrosine B as probe and their analytical applications. Talanta. 2015 Mar; 134(?):754-760. doi: 10.1016/j.talanta.2014.12.030. [PMID: 25618732]
  • Mingqiong Zhou, Jingdong Peng, Rongxing He, Yuting He, Jing Zhang, Aiping Li. High performance liquid chromatography coupled with resonance Rayleigh scattering for the detection of three fluoroquinolones and mechanism study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2015 Feb; 136 Pt B(?):1181-7. doi: 10.1016/j.saa.2014.10.004. [PMID: 25456660]
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  • Lakshmi Ganesan, Peter Buchwald. The promiscuous protein binding ability of erythrosine B studied by metachromasy (metachromasia). Journal of molecular recognition : JMR. 2013 Apr; 26(4):181-9. doi: 10.1002/jmr.2263. [PMID: 23456742]
  • Satoshi Horikoshi, Asami Higurashi, Emiko Kaneko, Hajime Yoshimura, Isao Ohsawa, Yusuke Suzuki, Chieko Hamada, Yasuhiko Tomino. A new screening method for proteinuria using Erythrosin B and an automated analyzer--rapid, sensitive and inexpensive determination. Clinica chimica acta; international journal of clinical chemistry. 2012 Jul; 413(13-14):1087-91. doi: 10.1016/j.cca.2012.02.029. [PMID: 22465201]
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  • Emiko Kaneko, Hiroko Yasuda, Asami Higurashi, Hajime Yoshimura. Spot test of urinary protein using erythrosin B and a membrane film. The Analyst. 2010 Jul; 135(7):1564-8. doi: 10.1039/c0an00107d. [PMID: 20485836]
  • Arindam Dalal, Mrinal K Poddar. Involvement of high plasma corticosterone status and activation of brain regional serotonin metabolism in long-term erythrosine-induced rearing motor hyper activity in young adult male rats. Toxicology mechanisms and methods. 2010 Jul; 20(6):287-97. doi: 10.3109/15376516.2010.483070. [PMID: 20465369]
  • Vinodaran M K Mathavan, Boon Kim Boh, Saad Tayyab. Characterization of erythrosine B binding to bovine serum albumin and bilirubin displacement. Indian journal of biochemistry & biophysics. 2009 Aug; 46(4):325-31. doi: NULL. [PMID: 19788065]
  • Rajeev Jain, Shalini Sikarwar. Adsorptive removal of Erythrosine dye onto activated low cost de-oiled mustard. Journal of hazardous materials. 2009 May; 164(2-3):627-33. doi: 10.1016/j.jhazmat.2008.08.043. [PMID: 18818014]
  • Mingyou Qin, Shaopu Liu, Zhongfang Liu, Xiaoli Hu. Resonance Rayleigh scattering spectra, non-linear scattering spectra of tetracaine hydrochloride-erythrosin system and its analytical application. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2009 Jan; 71(5):2063-8. doi: 10.1016/j.saa.2008.08.003. [PMID: 18976950]
  • Yumin You, Richard D Ludescher. The effect of salts on molecular mobility in amorphous sucrose monitored by erythrosin B phosphorescence. Carbohydrate research. 2008 Oct; 343(15):2641-9. doi: 10.1016/j.carres.2008.06.008. [PMID: 18771764]
  • Jian Wang, Zhongfang Liu, Jiangtao Liu, Shaopu Liu, Wei Shen. Study on the interaction between fluoroquinolones and erythrosine by absorption, fluorescence and resonance Rayleigh scattering spectra and their application. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2008 Mar; 69(3):956-63. doi: 10.1016/j.saa.2007.05.057. [PMID: 17618827]
  • Ming-You Qin, Shao-Pu Liu, Zhong-Fang Liu, Xiao-Li Hu. [Fluorescence quenching reaction of tetracaine hydrochloride with erythrosine and their analytical applications]. Guang pu xue yu guang pu fen xi = Guang pu. 2008 Feb; 28(2):389-93. doi: NULL. [PMID: 18479029]
  • Xiashi Zhu, Jing Sun, Yanyan Hu. Determination of protein by hydroxypropyl-beta-cyclodextrin sensitized fluorescence quenching method with erythrosine sodium as a fluorescence probe. Analytica chimica acta. 2007 Jul; 596(2):298-302. doi: 10.1016/j.aca.2007.06.008. [PMID: 17631110]
  • Alok Mittal, Jyoti Mittal, Lisha Kurup, A K Singh. Process development for the removal and recovery of hazardous dye erythrosine from wastewater by waste materials-Bottom Ash and De-Oiled Soya as adsorbents. Journal of hazardous materials. 2006 Nov; 138(1):95-105. doi: 10.1016/j.jhazmat.2006.05.038. [PMID: 16806679]
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