11'-Carboxy-gamma-chromanol (BioDeep_00000032693)

   

human metabolite Endogenous


代谢物信息卡片


(4R,8S)-11-[(2R)-6-hydroxy-2,7,8-trimethyl-3,4-dihydro-2H-1-benzopyran-2-yl]-4,8-dimethylundecanoic acid

化学式: C25H40O4 (404.29264400000005)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCC(=O)O)O
InChI: InChI=1S/C25H40O4/c1-17(8-6-9-18(2)11-12-23(27)28)10-7-14-25(5)15-13-21-16-22(26)19(3)20(4)24(21)29-25/h16-18,26H,6-15H2,1-5H3,(H,27,28)/t17-,18+,25+/m0/s1

描述信息

11-Carboxy-gamma-tocopherol is a dehydrogenation carboxylate product of 11-hydroxy-r-tocopherol by an unidentified microsomal enzyme(s) probably via an aldehyde intermediate. r-Tocopherol provides different antioxidant activities in food and in-vitro studies and showed higher activity in trapping lipophilic electrophiles and reactive nitrogen and oxygen species. From the metabolism end product, only that of r-tocopherol (2,7,8-trimethyl-2-(b-carboxyethyl)-6-hydroxychroman), but not that of a-tocopherol, was identified to provide natriuretic activity. Only the r-tocopherol plasma level served as biomarker for cancer and cardiovascular risk.
11-Carboxy-gamma-tocopherol is a dehydrogenation carboxylate product of 11-hydroxy-r-tocopherol by an unidentified microsomal enzyme(s) probably via an aldehyde intermediate

同义名列表

5 个代谢物同义名

(4R,8S)-11-[(2R)-6-hydroxy-2,7,8-trimethyl-3,4-dihydro-2H-1-benzopyran-2-yl]-4,8-dimethylundecanoic acid; (4R,8S)-11-[(2R)-6-hydroxy-2,7,8-trimethyl-3,4-dihydro-1-benzopyran-2-yl]-4,8-dimethylundecanoic acid; (4R,8S)-11-[(2R)-6-Hydroxy-2,7,8-trimethyl-3,4-dihydro-2H-1-benzopyran-2-yl]-4,8-dimethylundecanoate; 11-Carboxy-gamma-tocopherol; 11-Carboxy-gamma-chromanol



数据库引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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1 个相关的物种来源信息

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