Homovanillic acid sulfate (BioDeep_00000032181)

   

human metabolite Endogenous blood metabolite


代谢物信息卡片


(4-Hydroxy-3-methoxyphenyl)acetic acid sulphate

化学式: C9H10O7S (262.0147)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(urine) 24.87%

分子结构信息

SMILES: COC1=C(C=CC(=C1)CC(=O)O)OS(=O)(=O)O
InChI: InChI=1S/C9H10O7S/c1-15-8-4-6(5-9(10)11)2-3-7(8)16-17(12,13)14/h2-4H,5H2,1H3,(H,10,11)(H,12,13,14)

描述信息

Homovanillic acid sulfate is a component of olive oil and is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes and is associated with dopamine levels in the brain. In psychiatry and neuroscience, brain and cerebrospinal fluid levels of homovanillic acid (HVA) are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose. HVA presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma (Wikipedia). Homovanillic acid sulfate is an endogenous phenolic acid metabolite detected after the consumption of whole grain.
Homovanillic acid sulfate is a component of olive oil and is a major catecholamine metabolite.It is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.

同义名列表

25 个代谢物同义名

(4-Hydroxy-3-methoxyphenyl)acetic acid sulphate; 3’-Methoxy-4’-hydroxyphenylacetic acid sulphate; (4-Hydroxy-3-methoxyphenyl)acetic acid sulfate; 3’-Methoxy-4’-hydroxyphenylacetic acid sulfate; 4-Hydroxy-3-methoxybenzeneacetic acid sulphate; 4-Hydroxy-3-methoxybenzeneacetic acid sulfate; 3-Methoxy-4-hydroxyphenylacetic acid sulphate; 3-Methoxy-4-hydroxyphenylacetic acid sulfate; 2-[3-Methoxy-4-(sulphooxy)phenyl]acetic acid; 2-[3-methoxy-4-(sulfooxy)phenyl]acetic acid; [3-methoxy-4-(sulfooxy)phenyl]acetic acid; 3-Methoxy-4-(sulfooxy)-benzeneacetic acid; 3-Methoxy-4-(sulfooxy)benzeneacetic acid; 2-[3-Methoxy-4-(sulphooxy)phenyl]acetate; 2-[3-Methoxy-4-(sulfooxy)phenyl]acetate; 4-Sulfooxy-3-methoxy-benzeneacetic acid; 4-Sulfooxy-3-methoxyphenylacetic acid; Homovanillic acid sulphuric acid; Homovanillic acid sulfuric acid; Homovanillic acid sulphate; Vanilacetic acid sulphate; Homovanillic acid sulfate; Vanilacetic acid sulfate; Homovanillate sulphate; Homovanillate sulfate



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Richard D Beger, Ricky D Holland, Jinchun Sun, Laura K Schnackenberg, Page C Moore, Catherine L Dent, Prasad Devarajan, Didier Portilla. Metabonomics of acute kidney injury in children after cardiac surgery. Pediatric nephrology (Berlin, Germany). 2008 Jun; 23(6):977-84. doi: 10.1007/s00467-008-0756-7. [PMID: 18320237]
  • Karina de la Torre-Carbot, Jorge L Chávez-Servín, Olga Jaúregui, Ana I Castellote, Rosa M Lamuela-Raventós, Montserrat Fitó, María-Isabel Covas, Daniel Muñoz-Aguayo, M Carmen López-Sabater. Presence of virgin olive oil phenolic metabolites in human low density lipoprotein fraction: determination by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Analytica chimica acta. 2007 Feb; 583(2):402-10. doi: 10.1016/j.aca.2006.10.029. [PMID: 17386573]
  • Karina de la Torre-Carbot, Olga Jauregui, Ana I Castellote, Rosa M Lamuela-Raventós, María-Isabel Covas, Isidre Casals, M Carmen López-Sabater. Rapid high-performance liquid chromatography-electrospray ionization tandem mass spectrometry method for qualitative and quantitative analysis of virgin olive oil phenolic metabolites in human low-density lipoproteins. Journal of chromatography. A. 2006 May; 1116(1-2):69-75. doi: 10.1016/j.chroma.2006.03.022. [PMID: 16603168]