15-HEPE (BioDeep_00000031346)

   

human metabolite Endogenous blood metabolite


代谢物信息卡片


(5Z,8Z,11Z,13E,17Z)-16-hydroxyicosa-5,8,11,13,17-pentaenoic acid

化学式: C20H30O3 (318.21948299999997)
中文名称:
谱图信息: 最多检出来源 Danio rerio(blood) 22.22%

分子结构信息

SMILES: CC/C=C\CC(/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O)O
InChI: InChI=1S/C20H30O3/c1-2-3-16-19(21)17-14-12-10-8-6-4-5-7-9-11-13-15-18-20(22)23/h3-5,8-12,14,16,19,21H,2,6-7,13,15,17-18H2,1H3,(H,22,23)

描述信息

15-HEPE has been identified as a possible anti-inflammatory metabolite, and its elevated presence in the epidermis of animals fed oils rich in 20:5(n-3) or 18:3(n-6) may provide a mechanism for the beneficial effects of these oils on inflammatory conditions. 15-HEPE is a metabolite of eicosapentaenoic acid (EPA) which has anti-inflammatory properties and plays an important role in the resolution phase of inflammation. 15-HEPE is deposited in the epidermis, particularly in the metabolically active basal layer. This is considered advantageous in psoriasis therapy. (PMID: 17540633, 2106017) [HMDB]
15-HEPE has been identified as a possible anti-inflammatory metabolite, and its elevated presence in the epidermis of animals fed oils rich in 20:5(n-3) or 18:3(n-6) may provide a mechanism for the beneficial effects of these oils on inflammatory conditions. 15-HEPE is a metabolite of eicosapentaenoic acid (EPA) which has anti-inflammatory properties and plays an important role in the resolution phase of inflammation. 15-HEPE is deposited in the epidermis, particularly in the metabolically active basal layer. This is considered advantageous in psoriasis therapy. (PMID: 17540633, 2106017).

同义名列表

12 个代谢物同义名

(5Z,8Z,11Z,13E,17Z)-16-hydroxyicosa-5,8,11,13,17-pentaenoic acid; (15R)-15-Hydroxyeicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid; (15S)-15-Hydroxyeicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid; (15R)-15-Hydroxyeicosa-5Z,8Z,11Z,13E,17Z-pentaenoate; (15S)-15-Hydroxyeicosa-5Z,8Z,11Z,13E,17Z-pentaenoate; 15-Hydroxy-5,8,11,13,17-eicosapentaenoic acid; 15-Hydroxy-5,8,11,13,17-eicosapentaenoate; 15-Hydroxyeicosapentaenoic acid; 15-Hydroxyeicosapentaenoate; 15(R)-HEPE; 15(S)-HEPE; 15-HEPE



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

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