Linoelaidic acid (BioDeep_00000028189)

Main id: BioDeep_00000002188

 

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds natural product


代谢物信息卡片


(9E,12E)-octadeca-9,12-dienoic acid

化学式: C18H32O2 (280.2402172)
中文名称: 亚麻酸 C18:2, 葡萄籽油, 反亚油酸, 亚油酸, 亚油酸，罂酸, 亚油酸60-74\%
谱图信息: 最多检出来源 Homo sapiens(blood) 0.17%

Reviewed

Last reviewed on 2024-06-29.

Cite this Page

Linoelaidic acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/linoelaidic_acid (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000028189). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCC/C=C/C/C=C/CCCCCCCC(=O)O
InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6+,10-9+

描述信息

Linoelaidic acid is an isomer of linoleic acid, or conjugated linoleic acid (CLA), a derivative of a fatty acid linoleic acid. Conjugated linoleic acid (CLA) isomers, a group of positional and geometric isomers of linoleic acid [18:2(n-6)], have been studied extensively due to their ability to modulate cancer, atherosclerosis, obesity, immune function and diabetes in a variety of experimental models. CLAs ability to modulate human obesity remains controversial because data from clinical trials using mixed isomers are conflicting. (PMID 10759137). Trans fatty acids are characteristically produced during industrial hydrogenation of plant oils.
Linoelaidic acid is an isomer of linoleic acid, or conjugated linoleic acid (CLA), a derivative of a fatty acid linoleic acid. Conjugated linoleic acid (CLA) isomers, a group of positional and geometric isomers of linoleic acid [18:2(n-6)], have been studied extensively due to their ability to modulate cancer, atherosclerosis, obesity, immune function and diabetes in a variety of experimental models. CLAs ability to modulate human obesity remains controversial because data from clinical trials using mixed isomers are conflicting. (PMID 10759137)

Linolelaidic acid. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=506-21-8 (retrieved 2024-06-29) (CAS RN: 506-21-8). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Linolelaidic acid (Linoelaidic acid), an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research[1].
Linolelaidic acid (Linoelaidic acid), an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research[1].

同义名列表

36 个代谢物同义名

Linoleic acid, potassium salt, (Z,Z)-isomer; Linoleic acid, ammonium salt, (Z,Z)-isomer; Linoleic acid, calcium salt, (Z,Z)-isomer; Linoleic acid, sodium salt, (e,e)-isomer; Linoleic acid, (Z,Z)-isomer, 14C-labeled; Linoleic acid, sodium salt, (Z,Z)-isomer; trans,trans-9,12-Octadecadienoic acid; 9-trans,12-trans-Octadecadienoic acid; 9 trans,12 trans Octadecadienoic acid; (9E,12E)-octadeca-9,12-dienoic acid; (9E,12E)-9,12-Octadecadienoic acid; cis,cis-9,12-octadecadienoic acid; (9E,12E)-9,12-Octadecadienoate; Linoelaidic acid, (e,Z)-isomer; trans-9,trans-12-Linoleic acid; 9E,12E-octadecadienoic acid; Linoleic acid, (e,e)-isomer; Linoleic acid, (Z,Z)-isomer; Linoleic acid, (Z,e)-isomer; trans-9,trans-12-Linoleate; Acid, 9,12-octadecadienoic; 9,12 Octadecadienoic acid; 9,12-Octadecadienoic acid; 9E,12E-Octadecadienoate; C18:2, N-6,9 all-trans; 18:2, N-6,9 all-trans; Linolelaidic acid; Linoelaidic acid; Grape Seed Oil; Linoleic acid; Linoelaidate; Linoleate; Linoelaidic acid; Linoleate; Linoelaidic acid; Linoleic acid



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

77 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shuo Wang, Wenbin Zhou, Zhongyu Wei, Hang Li, Yuxiu Xiao. Solvent-tuned perovskite heterostructures enable visual linoleic acid assay and edible oil species discrimination via wavelength shift. Food chemistry. 2024 Aug; 449(?):139190. doi: 10.1016/j.foodchem.2024.139190. [PMID: 38579653]
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  • Haifaa Laroui, Thoraya Guemmaz, Fatima Zerargui, Karima Saffidine, Sara Guenifi, Lekhmici Arrar, Seddik Khennouf, Gokhan Zengin, Abderrahmane Baghiani. Antioxidant and anti-inflammatory potentials of Ammodaucus leucotrichus Coss. & Durieu seeds' extracts: In vitro and in vivo studies. Journal of ethnopharmacology. 2024 May; 326(?):117964. doi: 10.1016/j.jep.2024.117964. [PMID: 38401663]
  • Swaraj Kumar Babu, Dibya Ranjan Sahoo, Prajna Parimita Mohanta, Pradeep Kumar Naik. Exploring the antifilarial potential of an important medicinal plant Typhonium trilobatum (L. Schoot): Isolation, characterization, and structural elucidation of bioactive compounds against Brugia malayi. Journal of ethnopharmacology. 2024 May; 326(?):117858. doi: 10.1016/j.jep.2024.117858. [PMID: 38346526]
  • Tianmu He, Lijuan Xiong, Kexin Lin, Jing Yi, Cancan Duan, Jianyong Zhang. Functional metabolomics reveals arsenic-induced inhibition of linoleic acid metabolism in mice kidney in drinking water. Environmental pollution (Barking, Essex : 1987). 2024 May; 349(?):123949. doi: 10.1016/j.envpol.2024.123949. [PMID: 38636836]
  • Jingzhi Nie, Wenyue Ma, Xueyuan Ma, De Zhu, Xin Li, Caijin Wang, Guofeng Xu, Canni Chen, Dengjie Luo, Sichen Xie, Guanjing Hu, Peng Chen. Integrated Transcriptomic and Metabolomic Analysis Reveal the Dynamic Process of Bama Hemp Seed Development and the Accumulation Mechanism of α-Linolenic Acid and Linoleic Acid. Journal of agricultural and food chemistry. 2024 May; 72(19):10862-10878. doi: 10.1021/acs.jafc.3c09309. [PMID: 38712687]
  • Xiao-Yu Zhang, Kai-Rou Xia, Ya-Ni Wang, Pei Liu, Er-Xin Shang, Cong-Yan Liu, Yu-Ping Liu, Ding Qu, Wei-Wen Li, Jin-Ao Duan, Yan Chen, Huang-Qin Zhang. Unraveling the pharmacodynamic substances and possible mechanism of Trichosanthis Pericarpium in the treatment of coronary heart disease based on plasma pharmacochemistry, network pharmacology and experimental validation. Journal of ethnopharmacology. 2024 May; 325(?):117869. doi: 10.1016/j.jep.2024.117869. [PMID: 38342153]
  • Zongyao Huyan, Nicoletta Pellegrini, Josep Rubert, Wilma T Steegenga, Edoardo Capuano. Levels of lipid-derived gut microbial metabolites differ among plant matrices in an in vitro model of colon fermentation. Food research international (Ottawa, Ont.). 2024 May; 184(?):114230. doi: 10.1016/j.foodres.2024.114230. [PMID: 38609219]
  • Guiping Gong, Linpei Liu, Bo Wu, Jianting Li, Mingxiong He, Guoquan Hu. Simultaneous production of algal biomass and lipid by heterotrophic cultivation of linoleic acid-rich oleaginous microalga Chlorella sorokiniana using high acetate dosage. Bioresource technology. 2024 May; 399(?):130566. doi: 10.1016/j.biortech.2024.130566. [PMID: 38467262]
  • Natalia Łozińska, Julia Maldonado-Valderrama, Teresa Del Castillo-Santaella, Yanija Zhou, Dorota Martysiak-Żurowska, Yuanqi Lu, Christian Jungnickel. Bile conjugation and its effect on in vitro lipolysis of emulsions. Food research international (Ottawa, Ont.). 2024 May; 184(?):114255. doi: 10.1016/j.foodres.2024.114255. [PMID: 38609233]
  • Zhixiong Chen, Ni Hong, Cui Yan, Zhongbo Zheng, Jie Xi, Ping Cao. The potential of Paeonia lactiflora pall seeds oil as a pure natural cosmetics raw material: In Vitro findings. Journal of cosmetic dermatology. 2024 May; 23(5):1875-1883. doi: 10.1111/jocd.16204. [PMID: 38450923]
  • Xuan Liu, Weifei Wang, Zhong Li, Long Xu, Dongming Lan, Yonghua Wang. Lipidomics analysis unveils the dynamic alterations of lipid degradation in rice bran during storage. Food research international (Ottawa, Ont.). 2024 May; 184(?):114243. doi: 10.1016/j.foodres.2024.114243. [PMID: 38609222]
  • Nobuyuki Fukuoka, Ryusei Watanabe, Tatsuro Hamada. Impact of changes in root biomass on the occurrence of internal browning in radish root. Plant physiology and biochemistry : PPB. 2024 May; 210(?):108563. doi: 10.1016/j.plaphy.2024.108563. [PMID: 38554535]
  • Xueyan Gu, Heng Wang, Lei Wang, Kang Zhang, Yuhu Tian, Xiaoya Wang, Guowei Xu, Zhiting Guo, Saad Ahmad, Hanyurwumutima Egide, Jiahui Liu, Jianxi Li, Huub F J Savelkoul, Jingyan Zhang, Xuezhi Wang. The antioxidant activity and metabolomic analysis of the supernatant of Streptococcus alactolyticus strain FGM. Scientific reports. 2024 04; 14(1):8413. doi: 10.1038/s41598-024-58933-8. [PMID: 38600137]
  • Barbara Soldo, Maja Jukić Špika, Igor Pasković, Elma Vuko, Marija Polić Pasković, Ivica Ljubenkov. The Composition of Volatiles and the Role of Non-Traditional LOX on Target Metabolites in Virgin Olive Oil from Autochthonous Dalmatian Cultivars. Molecules (Basel, Switzerland). 2024 Apr; 29(8):. doi: 10.3390/molecules29081696. [PMID: 38675515]
  • Guanglei Ma, Bijie Hu, Siyin Yang, Zixuan Cen, Yiran Zheng, Yan Dong. Benzoxazinoids secreted by wheat root weaken the pathogenicity of Fusarium oxysporum f. sp. fabae by inhibiting linoleic acid and nucleotide metabolisms. Plant cell reports. 2024 Apr; 43(4):109. doi: 10.1007/s00299-024-03188-w. [PMID: 38564014]
  • Kun-Pyo Kim, Kyung-Oh Shin, Sangmin Lee, Jihyeon Yun, Taehoon Lee, Yunhi Cho. PNPLA1 knockdown inhibits esterification of γ-linolenic acid to ceramide 1 in differentiated keratinocytes. Biochemical and biophysical research communications. 2024 Apr; 702(?):149618. doi: 10.1016/j.bbrc.2024.149618. [PMID: 38340658]
  • Keita Nakatsutsumi, Koji Morishita, Todd W Costantini, Tomohiro Adachi, Akira Suekane, Keisuke Suzuki, Mitsuaki Kojima, Makoto Arita, Yasuhiro Otomo. Analysis of lipid metabolites derived from gut microbiota in ischemia-reperfusion model. The journal of trauma and acute care surgery. 2024 Apr; 96(4):542-547. doi: 10.1097/ta.0000000000004230. [PMID: 38079251]
  • Farah M Joujou, Nada El Darra, Hiba N Rajha, Elie Salem Sokhn, Nisreen Alwan. Evaluation of synergistic/antagonistic antibacterial activities of fatty oils from apricot, date, grape, and black seeds. Scientific reports. 2024 03; 14(1):6532. doi: 10.1038/s41598-024-54850-y. [PMID: 38503788]
  • Qing Zhang, Jiaping Ke, Piaopiao Long, Mingchun Wen, Zisheng Han, Liang Zhang, Mengting Zhu. Formation of Furan from Linoleic Acid Thermal Oxidation: (E,E)-2,4-Decadienal as a Critical Intermediate Product. Journal of agricultural and food chemistry. 2024 Feb; 72(8):4384-4392. doi: 10.1021/acs.jafc.3c08604. [PMID: 38354408]
  • Akane Suda, Banlanjo Abdulaziz Umaru, Yui Yamamoto, Hiroki Shima, Yuriko Saiki, Yijun Pan, Liang Jin, Jiaqi Sun, Yi Ling Clare Low, Chitose Suzuki, Takaaki Abe, Kazuhiko Igarashi, Toru Furukawa, Yuji Owada, Yoshiteru Kagawa. Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth. Scientific reports. 2024 02; 14(1):4409. doi: 10.1038/s41598-024-55050-4. [PMID: 38388563]
  • Yoshiro Saito, Noriko Noguchi, Etsuo Niki. Cholesterol is more readily oxidized than phospholipid linoleates in cell membranes to produce cholesterol hydroperoxides. Free radical biology & medicine. 2024 Feb; 211(?):89-95. doi: 10.1016/j.freeradbiomed.2023.12.011. [PMID: 38101585]
  • Dandan Yue, Xuyang Hao, Bei Han, Jiao Xu, Weinan Sun, Xiaoping Guo, Xianlong Zhang, Xiyan Yang. GhL1L1 regulates the contents of unsaturated fatty acids by activating the expression of GhFAD2 genes in cotton. Gene. 2024 Jan; 893(?):147899. doi: 10.1016/j.gene.2023.147899. [PMID: 37839764]
  • Ichiro Koshiishi. [What is the Initiating Reaction for the Lipid Radical Chain Reaction System That can Induce Ferroptotic Cell Death at the Lower Oxygen Content?]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024 Jan; ?(?):. doi: 10.1248/yakushi.23-00207. [PMID: 38246655]
  • Nirajan Shrestha, Simone L Sleep, Olivia J Holland, Josif Vidimce, Andrew C Bulmer, James S M Cuffe, Anthony V Perkins, Andrew J McAinch, Deanne H Hryciw. Maternal Diet High in Linoleic Acid Alters Offspring Lipids and Hepatic Regulators of Lipid Metabolism in an Adolescent Rat Model. International journal of molecular sciences. 2024 Jan; 25(2):. doi: 10.3390/ijms25021129. [PMID: 38256199]
  • Ufaq Fayaz, Syed Zameer Hussain, Bazila Naseer, Syed Sheraz Mahdi, Javid Iqbal Mir, Alokesh Ghosh, Arun Jana, Nazrana Rafique Wani, Abida Jabeen, Fehim J Wani, Sobiya Manzoor. Flavor profiling and gene expression studies of indigenous aromatic rice variety (Mushk Budiji) grown at different altitudes of Highland Himalayan regions. Scientific reports. 2024 01; 14(1):1010. doi: 10.1038/s41598-024-51467-z. [PMID: 38200065]
  • Yunping Yao, Tianliang Wang, Zhiyuan Qiang, Wenqi Du, Changmo Li. Mechanisms of the Formation of Nonvolatile and Volatile Oxidation Products from Methyl Linoleic Acid at High Temperatures. Journal of agricultural and food chemistry. 2024 Jan; 72(1):704-714. doi: 10.1021/acs.jafc.3c04405. [PMID: 38131267]
  • Xiaoli Yang, Chenglin Chi, Wenjing Li, Yanyan Zhang, Shufang Yang, Ruoxuan Xu, Rongxia Liu. Metabolomics and lipidomics combined with serum pharmacochemistry uncover the potential mechanism of Huang-Lian-Jie-Du decoction alleviates atherosclerosis in ApoE-/- mice. Journal of ethnopharmacology. 2024 Jan; 324(?):117748. doi: 10.1016/j.jep.2024.117748. [PMID: 38216103]
  • Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D Hammock, Andreas Weigert, Timo Frömel, Ingrid Fleming. Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Jan; 171(?):116127. doi: 10.1016/j.biopha.2024.116127. [PMID: 38198951]
  • Radosław Kowalski, Grażyna Kowalska, Przemysław Mitura, Rafał Rowiński, Urszula Pankiewicz, Joanna Hawlena. The Effect of Peppermint and Thyme Oils on Stabilizing the Fatty Acid Profile of Sunflower Oil. Molecules (Basel, Switzerland). 2024 Jan; 29(2):. doi: 10.3390/molecules29020292. [PMID: 38257205]
  • Xuemei Bao, Danmin Ke, Wei Wang, Fahui Ye, Jiangyi Zeng, Yuan Zong. High fatty acid accumulation and coloration molecular mechanism of the elm mushroom (Pleurotus citrinopileatus). Bioscience, biotechnology, and biochemistry. 2024 Jan; ?(?):. doi: 10.1093/bbb/zbad183. [PMID: 38171531]
  • Cheng-Lu Yu, Fang Lu, Dong-Hua Yu, Xiao-Min Xu, Peng Xu, Shu-Min Liu. [Mechanism of acteoside in prevention and treatment of gouty arthritis based on liver metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Jan; 49(1):224-231. doi: 10.19540/j.cnki.cjcmm.20230808.402. [PMID: 38403355]
  • Prapaporn Chaniad, Arisara Phuwajaroanpong, Walaiporn Plirat, Atthaphon Konyanee, Abdi Wira Septama, Chuchard Punsawad. Assessment of antimalarial activity of crude extract of Chan-Ta-Lee-La and Pra-Sa-Chan-Dang formulations and their plant ingredients for new drug candidates of malaria treatment: In vitro and in vivo experiments. PloS one. 2024; 19(1):e0296756. doi: 10.1371/journal.pone.0296756. [PMID: 38206944]
  • Chen Wu, Haiqin Chen, Yongchao Mei, Bo Yang, Jianxin Zhao, Catherine Stanton, Wei Chen. Advances in research on microbial conjugated linoleic acid bioconversion. Progress in lipid research. 2024 Jan; 93(?):101257. doi: 10.1016/j.plipres.2023.101257. [PMID: 37898352]
  • Teng Wei, Dengfeng Tan, Shengyue Zhong, Hong Zhang, Zeyuan Deng, Jing Li. Differences in Absorption and Metabolism between Structured 1,3-Oleate-2-palmitate Glycerol and 1-Oleate-2-palmitate-3-linoleate Glycerol on C57BL/6J Mice. Journal of agricultural and food chemistry. 2023 Dec; 71(49):19610-19621. doi: 10.1021/acs.jafc.3c07234. [PMID: 38038963]
  • Kangjun Fan, Yonghua Qin, Xueli Hu, Jindong Xu, Qingzhi Ye, Chengyang Zhang, Yangyang Ding, Gang Li, Yan Chen, Jiao Liu, Peiqi Wang, Zunhong Hu, Xingchu Yan, Hairong Xiong, Hong Liu, Rui Qin. Identification of genes associated with fatty acid biosynthesis based on 214 safflower core germplasm. BMC genomics. 2023 Dec; 24(1):763. doi: 10.1186/s12864-023-09874-5. [PMID: 38082219]
  • Na Li, Xuan Wu, Hailong Liu, Diandong Xie, Shuqi Hao, Zeyu Lu, Wei Quan, Jie Chen, Huaide Xu, Mei Li. Effect of edible oil type on the formation of protein-bound Nε-(carboxymethyl)lysine in roasted pork patties. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 1):113628. doi: 10.1016/j.foodres.2023.113628. [PMID: 37986479]
  • Shiyun Xian, Jiabin Zhu, Yuchen Wang, Haihan Song, Hangxiang Wang. Oral liposomal delivery of an activatable budesonide prodrug reduces colitis in experimental mice. Drug delivery. 2023 Dec; 30(1):2183821. doi: 10.1080/10717544.2023.2183821. [PMID: 36861451]
  • Qinghai Wu, Min Zhuang, Tianlong Guo, Sanyue Bao, Sachula Wu, Sheng Ke, Xuanyu Wang, Anqi Wang, Zhongkai Zhou. Gut microbiota, host lipid metabolism and regulation mechanism of high-fat diet induced mice following different probiotics-fermented wheat bran intervention. Food research international (Ottawa, Ont.). 2023 Dec; 174(Pt 1):113497. doi: 10.1016/j.foodres.2023.113497. [PMID: 37986413]
  • S A Gabr, W M Elsaed, M A Eladl, G A Ghoniem, M El-Sherbiny, K S El-Bayoumi, H Abouhish, A M Desouky, M M Abdel-Aziz, M Eldesoqui, M Elshafey, H A Ebrahim, N S Nosseir, A M R El-Sayed. Circulating microRNAs as novel biomarkers for measuring the potency of ginger extract against cyclophosphamide toxicity in rat renal tissues: molecular and histopathological study. European review for medical and pharmacological sciences. 2023 Nov; 27(22):10815-10830. doi: 10.26355/eurrev_202311_34448. [PMID: 38039010]
  • Junjun Jiang, Qianqian Shi, Xi Li, Xueying He, Cuiyun Wu, Xingang Li. Biological Characteristics and Functional Analysis of the Linoleic Acid Synthase Gene ZjFAD2 in Jujube. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015479. [PMID: 37895156]
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  • Tiziana Maria Sirangelo, Ivano Forgione, Samanta Zelasco, Cinzia Benincasa, Enzo Perri, Elisa Vendramin, Federica Angilè, Francesco Paolo Fanizzi, Francesco Sunseri, Amelia Salimonti, Fabrizio Carbone. Combined Transcriptomic and Metabolomic Approach Revealed a Relationship between Light Control, Photoprotective Pigments, and Lipid Biosynthesis in Olives. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914448. [PMID: 37833896]
  • Qiong Wang, Xingguo Wang. The Effect of Plant-Derived Low-Ratio Linoleic Acid/α-Linolenic Acid on Markers of Glucose Controls: A Systematic Review and Meta-Analysis. International journal of molecular sciences. 2023 Sep; 24(18):. doi: 10.3390/ijms241814383. [PMID: 37762686]
  • Mengyuan Chen, Jingjing Dong, Xiaole Zhao, Xiaoyao Yin, Kejia Wu, Qiao Wang, Xin Liu, Yongning Wu, Zhiyong Gong. Cadmium influence on lipid metabolism in Sprague-Dawley rats through linoleic acid and glycerophospholipid metabolism pathways. Journal of biochemical and molecular toxicology. 2023 Sep; 37(9):e23412. doi: 10.1002/jbt.23412. [PMID: 37341456]
  • Sonia Salaria, J Lucas Boatwright, Nathan Johnson, Amod Madurapperumage, Priyanka Joshi, Pushparajah Thavarajah, George Vandemark, Dil Thavarajah. Fatty acid composition and genome-wide associations of a chickpea (Cicer arietinum L.) diversity panel for biofortification efforts. Scientific reports. 2023 Aug; 13(1):14002. doi: 10.1038/s41598-023-41274-3. [PMID: 37635199]
  • Elisabeth Koch, Ariane Löwen, Nadja Kampschulte, Kathrin Plitzko, Michelle Wiebel, Katharina M Rund, Ina Willenberg, Nils Helge Schebb. Beyond Autoxidation and Lipoxygenases: Fatty Acid Oxidation Products in Plant Oils. Journal of agricultural and food chemistry. 2023 Aug; ?(?):. doi: 10.1021/acs.jafc.3c02724. [PMID: 37624576]
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  • Dóra Kovács, Emanuela Camera, Szilárd Póliska, Alessia Cavallo, Miriam Maiellaro, Katalin Dull, Florian Gruber, Christos C Zouboulis, Andrea Szegedi, Dániel Törőcsik. Linoleic Acid Induced Changes in SZ95 Sebocytes-Comparison with Palmitic Acid and Arachidonic Acid. Nutrients. 2023 Jul; 15(15):. doi: 10.3390/nu15153315. [PMID: 37571253]
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  • Natasha Z Anita, Felicia Kwan, Si Won Ryoo, Chelsi Major-Orfao, William Z Lin, Shiropa Noor, Krista L Lanctôt, Nathan Herrmann, Paul I Oh, Baiju R Shah, Jeremy Gilbert, Angela Assal, Ilana J Halperin, Ameer Y Taha, Walter Swardfager. Cytochrome p450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes. Journal of lipid research. 2023 May; ?(?):100395. doi: 10.1016/j.jlr.2023.100395. [PMID: 37245563]
  • Olga Yu Selyutina, Viktor A Timoshnikov, Nikolay E Polyakov, George J Kontoghiorghes. Metal Complexes of Omadine (N-Hydroxypyridine-2-thione): Differences of Antioxidant and Pro-Oxidant Behavior in Light and Dark Conditions with Possible Toxicity Implications. Molecules (Basel, Switzerland). 2023 May; 28(10):. doi: 10.3390/molecules28104210. [PMID: 37241949]
  • Jiaqi Xie, Yihong Li, Yulu Liang, Hongqian Kui, Can Wang, Jianmei Huang. Integration of non-targeted metabolomics with network pharmacology deciphers the anxiolytic mechanisms of Platycladi Semen extracts in CUMS mice. Journal of ethnopharmacology. 2023 May; ?(?):116571. doi: 10.1016/j.jep.2023.116571. [PMID: 37201666]
  • Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products. ACS pharmacology & translational science. 2023 May; 6(5):683-701. doi: 10.1021/acsptsci.2c00194. [PMID: 37200814]
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  • Huiting Lin, Yan Liang, Kumaravel Kaliaperumal, Qin Xiong, Shuo Duan, Yueming Jiang, Jun Zhang. Linoleic acid from the endophytic fungus Diaporthe sp. HT-79 inhibits the growth of Xanthomonas citri subsp. citri by destructing the cell membrane and producing reactive oxygen species (ROS). Pesticide biochemistry and physiology. 2023 May; 192(?):105423. doi: 10.1016/j.pestbp.2023.105423. [PMID: 37105613]
  • Lei Ma, Shaoying Ma, Guiping Chen, Xu Lu, Ruonan Wei, Ling Xu, Xiaojie Feng, Xiaoming Yang, Qiang Chai, Xucheng Zhang, Sheng Li. New insights into the occurrence of continuous cropping obstacles in pea (Pisum sativum L.) from soil bacterial communities, root metabolism and gene transcription. BMC plant biology. 2023 Apr; 23(1):226. doi: 10.1186/s12870-023-04225-8. [PMID: 37106450]
  • Carla Del Carpio-Jiménez, Ruth Sara Molleda-Gutierrez, Profeta Tapia-Delgado. Evaluation of Properties of Chenopodium pallidicaule (Cañihua) Oil for Possible Use in Cosmetic Formulations. Journal of oleo science. 2023 Apr; 72(5):501-509. doi: 10.5650/jos.ess22318. [PMID: 37045752]
  • Liguo Liu, Dongmei Xu, Fengxin Chen, Shengnan Cai, Jin Wei, Jiaheng Deng, Jianhua Zheng, Qi Jin, Wenhui Lun. Identification of potential biomarkers for diagnosis of syphilis from the cerebrospinal fluid based on untargeted metabolomic analysis. Molecular omics. 2023 Apr; ?(?):. doi: 10.1039/d3mo00026e. [PMID: 37185577]
  • Jason M Meyer, William E Boeglin, Alan R Brash. Recombinant PNPLA1 catalyzes the synthesis of acylceramides and acyl acids with selective incorporation of linoleic acid. Journal of lipid research. 2023 Apr; ?(?):100379. doi: 10.1016/j.jlr.2023.100379. [PMID: 37087101]
  • Yuan-Han Zhong, Jian Liang, Qian Qin, Yu-Jie Wang, Yi-Ming Peng, Ting Zhang, Fang-Yuan Liu, Xin-Yu Zhang, Jun-Wei He, Shou-Wen Zhang, Guo-Yue Zhong, Hui-Lian Huang, Jin-Xiang Zeng. The activities and mechanisms of intestinal microbiota metabolites of TCM herbal ingredients could be illustrated by a strategy integrating spectrum-effects, network pharmacology, metabolomics and molecular docking analysis: Platycodin D as an example. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Apr; 115(?):154831. doi: 10.1016/j.phymed.2023.154831. [PMID: 37094423]
  • Maria Nancy N de Lima, Jamile Silva da Costa, Bruna A Guimarães, Jofre Jacob S Freitas, William N Setzer, Joyce Kelly R da Silva, José Guilherme S Maia, Pablo Luis B Figueiredo. Chemometrics of the Composition and Antioxidant Capacity of Hyptis crenata Essential Oils from Brazil. Molecules (Basel, Switzerland). 2023 Apr; 28(8):. doi: 10.3390/molecules28083371. [PMID: 37110606]
  • Elek Ferencz, Gabriella Spengler, István Zupkó, Martin Vollár, Zoltán Péter Zomborszki, Norbert Kúsz, Judit Hohmann, Balázs Kovács, Dezső Csupor, Eszter Laczkó-Zöld, Boglárka Csupor-Löffler. Isolation of compounds from the roots of Ambrosia artemisiifolia and their effects on human cancer cell lines. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2023 Apr; ?(?):. doi: 10.1515/znc-2022-0239. [PMID: 37029666]
  • Ke Sui, Ali Yasrebi, Natasha Malonza, Zehra H Jaffri, Samuel E Fisher, Isaac Seelenfreund, Brandon D McGuire, Savannah A Martinez, Avery T MacDonell, Kevin M Tveter, Candace R Longoria, Sue A Shapses, Sara C Campbell, Diana E Roopchand, Troy A Roepke. Saturated fatty acids and omega-3 polyunsaturated fatty acids improve metabolic parameters in ovariectomized female mice. Endocrinology. 2023 Apr; ?(?):. doi: 10.1210/endocr/bqad059. [PMID: 37029960]
  • Stanislav Macháček, Michal Tupec, Natan Horáček, Martina Halmová, Amit Roy, Aleš Machara, Pavlína Kyjaková, Ondřej Lukšan, Iva Pichová, Robert Hanus. Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites. Molecular biology and evolution. 2023 04; 40(4):. doi: 10.1093/molbev/msad087. [PMID: 37043525]
  • Fengjiao Zhang, Renjie Zhang, Songgui He, Jingyi Guan, Zhaoxing Feng, Zhenqiang Wu. Formation of free radicals in Chi-aroma Baijiu during aging process with fat pork. Free radical research. 2023 Apr; 57(4):271-281. doi: 10.1080/10715762.2023.2232095. [PMID: 37401820]
  • Esma Anissa Trad Khodja, Abd El Hamid Khabtane, Rabah Arhab, Djamila Benouchenne, Mohamed Sabri Bensaad, Chawki Bensouici, Ramazan Erenler. assessment of antioxidant, neuroprotective, anti-urease and anti-tyrosinase capacities of leaves extracts. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2023 Apr; 43(2):252-264. doi: 10.19852/j.cnki.jtcm.20230105.003. [PMID: 36994513]
  • Idir Moualek, Souad Lahcene, Mounir M Salem-Bekhit, Azmat Ali Khan, Amer M Alanazi, Karim Bariz, Amine Msela, Hillal Sebbane, Hyun-Kyung Park, Byong-Hun Jeon, Yacine Benguerba, Karim Houali. Assessment of the Antioxidant and Anti-inflammatory Properties of Aqueous Extract of Rosa sempervirens Leaves. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Mar; 69(3):214-222. doi: 10.14715/cmb/2023.69.3.31. [PMID: 37300666]
  • Adnan Kanbar, Julia Beisel, Meylin Terrel Gutierrez, Simone Graeff-Hönninger, Peter Nick. Peruvian Amaranth (kiwicha) Accumulates Higher Levels of the Unsaturated Linoleic Acid. International journal of molecular sciences. 2023 Mar; 24(7):. doi: 10.3390/ijms24076215. [PMID: 37047191]
  • Ferdinand Fandrei, Tomáš Havrišák, Lukáš Opálka, Oskar Engberg, AlbertA Smith, Petra Pullmannová, Norbert Kučerka, Veronika Ondrejčeková, Bruno Demé, Lucie Nováková, Miloš Steinhart, Kateřina Vávrová, Daniel Huster. The Intriguing Molecular Dynamics of Cer[EOS] in Rigid Skin Barrier Lipid Layers Requires Improvement of the Model. Journal of lipid research. 2023 Mar; ?(?):100356. doi: 10.1016/j.jlr.2023.100356. [PMID: 36948272]
  • Jay Shockey, Matthew K Gilbert, Gregory N Thyssen. A mutant cotton fatty acid desaturase 2-1d allele causes protein mistargeting and altered seed oil composition. BMC plant biology. 2023 Mar; 23(1):147. doi: 10.1186/s12870-023-04160-8. [PMID: 36932365]
  • Francisca S Teixeira, Lígia L Pimentel, Susana S M P Vidigal, João Azevedo-Silva, Manuela E Pintado, Luís M Rodríguez-Alcalá. Differential Lipid Accumulation on HepG2 Cells Triggered by Palmitic and Linoleic Fatty Acids Exposure. Molecules (Basel, Switzerland). 2023 Mar; 28(5):. doi: 10.3390/molecules28052367. [PMID: 36903612]
  • David R Lynch, Katherine D Mathews, Susan Perlman, Theresa Zesiewicz, Sub Subramony, Omid Omidvar, Adam P Vogel, Ana Krtolica, Nadia Litterman, Lex van der Ploeg, Frederic Heerinckx, Peter Milner, Mark Midei. Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia. Journal of neurology. 2023 Mar; 270(3):1615-1623. doi: 10.1007/s00415-022-11501-4. [PMID: 36462055]
  • Cheng Wang, Zhaojie Li, Wei Wu. Understanding fatty acid composition and lipid profile of rapeseed oil in response to nitrogen management strategies. Food research international (Ottawa, Ont.). 2023 03; 165(?):112565. doi: 10.1016/j.foodres.2023.112565. [PMID: 36869550]
  • Eric Haas, Yonggyun Kim, David Stanley. Why can insects not biosynthesize cholesterol?. Archives of insect biochemistry and physiology. 2023 Mar; 112(3):e21983. doi: 10.1002/arch.21983. [PMID: 36372906]
  • Liyun Zhao, Liyuan Yao, Rui Chen, Jiani He, Tingting Lin, Silin Qiu, Guohua Chen, Hongfeng Chen, Sheng-Xiang Qiu. Pinosrtobin from plants and propolis against human coronavirus HCoV-OC43 by modulating host AHR/CYP1A1 pathway and lipid metabolism. Antiviral research. 2023 Mar; 212(?):105570. doi: 10.1016/j.antiviral.2023.105570. [PMID: 36863496]
  • Anna Coenen, Manuel Ferrer, Karl-Erich Jaeger, Ulrich Schörken. Synthesis of 12-aminododecenoic acid by coupling transaminase to oxylipin pathway enzymes. Applied microbiology and biotechnology. 2023 Feb; ?(?):. doi: 10.1007/s00253-023-12422-6. [PMID: 36807735]
  • Francesco Gai, Michał A Janiak, Katarzyna Sulewska, Pier Giorgio Peiretti, Magdalena Karamać. Phenolic Compound Profile and Antioxidant Capacity of Flax (Linum usitatissimum L.) Harvested at Different Growth Stages. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041807. [PMID: 36838795]
  • Michael A Crawford, Andrew J Sinclair, Barbara Hall, Enitan Ogundipe, Yiqun Wang, Dimitrios Bitsanis, Ovrang B Djahanbakhch, Laurence Harbige, Ivan Golfetto, Therishnee Moodley, Ahmed Hassam, AnnieBelle Sassine, Mark Johnson. The imperative of arachidonic acid in human reproduction. Progress in lipid research. 2023 Feb; ?(?):101222. doi: 10.1016/j.plipres.2023.101222. [PMID: 36746351]
  • Zhipeng Yan, Shuyue Li, Rui Chen, Haohan Xie, Meiqiong Wu, Nan Nan, Qisong Xing, Yang Yun, Guohua Qin, Nan Sang. Effects of differential regional PM2.5 induced hepatic steatosis and underlying mechanism. Environmental pollution (Barking, Essex : 1987). 2023 Feb; 323(?):121220. doi: 10.1016/j.envpol.2023.121220. [PMID: 36746292]
  • Christine Toelzer, Kapil Gupta, Imre Berger, Christiane Schaffitzel. Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. Acta crystallographica. Section D, Structural biology. 2023 Feb; 79(Pt 2):111-121. doi: 10.1107/s2059798323000049. [PMID: 36762857]
  • Eva Tejedor-Calvo, Pedro Marco, Peter Spègel, Cristina Soler-Rivas. Extraction and trapping of truffle flavoring compounds into food matrices using supercritical CO2. Food research international (Ottawa, Ont.). 2023 02; 164(?):112422. doi: 10.1016/j.foodres.2022.112422. [PMID: 36737997]
  • Pollyane Gomes Corrêa, Leonardo Gomes Sanders Moura, Ana Claudia Fernandes Amaral, Maíra Martins H de Almeida, Francisca das Chagas do Amaral Souza, Jaime Paiva Lopes Aguiar, Renê Lemos Aleluia, Jefferson Rocha de Andrade Silva. Evaluation of the Amazonian fruit Ambelania acida: Chemical and nutritional studies. Journal of food science. 2023 Feb; 88(2):757-771. doi: 10.1111/1750-3841.16455. [PMID: 36633002]
  • C Rikard Unelius, Suresh Ganji, Paal Krokene. Linoleic Acid Promotes Emission of Bark Beetle Semiochemicals by Fungal Symbionts. Journal of chemical ecology. 2023 Feb; 49(1-2):59-66. doi: 10.1007/s10886-022-01400-3. [PMID: 36585598]
  • Yangyang Wang, Yanping Sun, Bingyou Yang, Qiuhong Wang, Haixue Kuang. Integrate metabolomics strategy and target prediction to reveal the ameliorate effect of four typical 'cold' property herbs on hyperthyroidism rats. Journal of ethnopharmacology. 2023 Jan; 301(?):115772. doi: 10.1016/j.jep.2022.115772. [PMID: 36202164]
  • Hong Jiang, Jie Chen, Xin Li, Yu-Te Zhong, Li-Ping Kang, Guohua Wang, Meng Yu, Li-Feng Fu, Ping Wang, Hai-Yu Xu. Systematic identification of chemical components in Fufang Shuanghua oral liquid and screening of potential active components against SARS-CoV-2 protease. Journal of pharmaceutical and biomedical analysis. 2023 Jan; 223(?):115118. doi: 10.1016/j.jpba.2022.115118. [PMID: 36332330]
  • Lu Liu, Qi Wang, Linfeng Zhu, Huiming Guo, Hongmei Cheng, Xiaofeng Su. Heat Shock Transcription Factor GhHSFB2a Is Crucial for Cotton Resistance to Verticillium dahliae. International journal of molecular sciences. 2023 Jan; 24(3):. doi: 10.3390/ijms24031845. [PMID: 36768168]