2-Ethylacrylic acid (BioDeep_00000027724)

   

human metabolite Endogenous


代谢物信息卡片


2-Methylene-6ci,7ci,8ci)-butyric acid

化学式: C5H8O2 (100.05242679999999)
中文名称: 2-乙基丙烯酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=C)C(=O)O
InChI: InChI=1S/C5H8O2/c1-3-4(2)5(6)7/h2-3H2,1H3,(H,6,7)

描述信息

2-ethylacrylic acid is an alpha, beta-unsaturated monocarboxylic acid that is acrylic acid in which the hydrogen at position 2 is substituted by an ethyl group. It has a role as a mammalian metabolite. It derives from an acrylic acid. It is a conjugate acid of a 2-ethylacrylate. 2-Ethylacrylic acid is an intermediate metabolite in the conversion of R-2-methylbutyrate into 2-ethylhydracrylic acid, which is variably increased in defects of isoleucine oxidation at distal steps in the catabolic pathway (3-oxoacyl-CoA thiolase deficiency and methylmalonyl-CoA mutase deficiency) (PMID 1016232).
2-Ethylacrylic acid is an intermediate metabolite in the conversion of R-2-methylbutyrate into 2-ethylhydracrylic acid, which is variably increased in defects of isoleucine oxidation at distal steps in the catabolic pathway (3-oxoacyl-CoA thiolase deficiency and methylmalonyl-CoA mutase deficiency) (PMID 1016232) [HMDB]

同义名列表

22 个代谢物同义名

2-Methylene-6ci,7ci,8ci)-butyric acid; 2-Methylene-6ci,7ci,8ci)-butyrate; alpha-Methylene-butanoic acid; 2-methylidenebutanoic acid; Butanoic acid,2-methylene-; Poly(2-ethylacrylic acid); Α-methylene-butanoic acid; alpha-Methylene-butanoate; a-Methylene-butanoic acid; 2-ethyl-2-propenoic acid; 2-Methylenebutyric acid; Α-methylene-butanoate; a-Methylene-butanoate; 2-Ethylpropenoic acid; 2-Ethyl-2-propenoate; 2-Ethylacrylic acid; 2-Methylenebutyrate; 2-Ethylpropenoate; 2-Ethyl acrylate; 2-Ethylacrylate; Ethacrylic acid; Ethacrylate



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tingli Lu, Zhao Wang, Yufan Ma, Yang Zhang, Tao Chen. Influence of polymer size, liposomal composition, surface charge, and temperature on the permeability of pH-sensitive liposomes containing lipid-anchored poly(2-ethylacrylic acid). International journal of nanomedicine. 2012; 7(?):4917-26. doi: 10.2147/ijn.s35576. [PMID: 23028220]
  • Roman Ashauer, Ivo Caravatti, Anita Hintermeister, Beate I Escher. Bioaccumulation kinetics of organic xenobiotic pollutants in the freshwater invertebrate Gammarus pulex modeled with prediction intervals. Environmental toxicology and chemistry. 2010 Jul; 29(7):1625-36. doi: 10.1002/etc.175. [PMID: 20821614]
  • Ru-tao Wang, Tao Chen, Zhao Wang, Min-quan Hui, Jing-guo Fu. [Property of liposomal fusion induced by acid-sensitive polymer]. Yao xue xue bao = Acta pharmaceutica Sinica. 2008 Sep; 43(9):951-5. doi: ". [PMID: 19048789]
  • Ru-tao Wang, Tao Chen, Zhao Wang, Ting-li Lu, Yue-hua He. [Acid-sensitive polymer liposomes prepared by poly(2-ethylacrylic acid) alkylamide derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica. 2007 Dec; 42(12):1303-8. doi: ". [PMID: 18338645]
  • Tao Chen, Deirdre McIntosh, Yuehua He, Jungsoo Kim, David A Tirrell, Peter Scherrer, David B Fenske, Ammen P Sandhu, Pieter R Cullis. Alkylated derivatives of poly(ethylacrylic acid) can be inserted into preformed liposomes and trigger pH-dependent intracellular delivery of liposomal contents. Molecular membrane biology. 2004 Nov; 21(6):385-93. doi: 10.1080/09687860400010516. [PMID: 15764368]
  • Venkataramana Vijay, Kevin McCusker. Recent advances in biocompatible surface-modifying additives for cardiopulmonary bypass. Perfusion. 2003 Mar; 18 Suppl 1(?):41-5. doi: 10.1191/0267659103pf626oa. [PMID: 12708764]
  • H Christensen, S Felby. Dibenzepine and its metabolites in blood, muscle, liver, vitreous body and urine from fatal poisoning. Acta pharmacologica et toxicologica. 1975 Nov; 37(5):393-401. doi: 10.1111/j.1600-0773.1975.tb00858.x. [PMID: 888]