Xanthone (BioDeep_00000276836)
Main id: BioDeep_00000017485
Secondary id: BioDeep_00000185032
natural product PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C13H8O2 (196.0524)
中文名称: 占吨酮
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 51.72%
分子结构信息
SMILES: c12c(oc3c(c1=O)cccc3)cccc2
InChI: InChI=1S/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
描述信息
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9192; ORIGINAL_PRECURSOR_SCAN_NO 9189
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9263; ORIGINAL_PRECURSOR_SCAN_NO 9262
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9233; ORIGINAL_PRECURSOR_SCAN_NO 9231
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9258; ORIGINAL_PRECURSOR_SCAN_NO 9255
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9245; ORIGINAL_PRECURSOR_SCAN_NO 9242
CONFIDENCE standard compound; INTERNAL_ID 198; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9280; ORIGINAL_PRECURSOR_SCAN_NO 9279
Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities[1].
Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities[1].
同义名列表
1 个代谢物同义名
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:37647
- PubChem: 7020
- Metlin: METLIN43571
- ChEMBL: CHEMBL186784
- KNApSAcK: C00040678
- CAS: 90-47-1
- MoNA: LU019806
- MoNA: LU019805
- MoNA: LU019804
- MoNA: LU019803
- MoNA: LU019802
- MoNA: LU019801
- MoNA: VF-NPL-LTQ006398
- MoNA: VF-NPL-LTQ006397
- MoNA: VF-NPL-QEHF003303
- MoNA: VF-NPL-QEHF003302
- MoNA: VF-NPL-QEHF003301
- MoNA: VF-NPL-QEHF003300
- MoNA: VF-NPL-QEHF003299
- MoNA: VF-NPL-QEHF003298
- PMhub: MS000011451
- KEGG: C22599
- medchemexpress: HY-N0126
- LOTUS: LTS0088534
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
22 个相关的物种来源信息
- 703253 - Calophyllaceae: LTS0088534
- 73121 - Calophyllum: LTS0088534
- 2759 - Eukaryota: LTS0088534
- 198767 - Harungana: LTS0088534
- 198768 - Harungana madagascariensis: 10.1021/NP060556L
- 198768 - Harungana madagascariensis: LTS0088534
- 629714 - Hypericaceae: LTS0088534
- 65561 - Hypericum perforatum: -
- 3495 - Maclura: LTS0088534
- 194324 - Maclura cochinchinensis: 10.1016/S0031-9422(00)98098-1
- 194324 - Maclura cochinchinensis: LTS0088534
- 3398 - Magnoliopsida: LTS0088534
- 3487 - Moraceae: LTS0088534
- 33090 - Plants: -
- 241806 - Polypodiopsida: LTS0088534
- 1203515 - Rhachidosoraceae: LTS0088534
- 208757 - Rhachidosorus: LTS0088534
- 65707 - Rhachidosorus mesosorus: 10.1248/CPB.32.4455
- 65707 - Rhachidosorus mesosorus: LTS0088534
- 35493 - Streptophyta: LTS0088534
- 58023 - Tracheophyta: LTS0088534
- 33090 - Viridiplantae: LTS0088534
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Bethanie Dean, Gemma Cooper, Maitreyi Shivkumar, Timothy J Snape. Hydroxy-xanthones as promising antiviral agents: Synthesis and biological evaluation against human coronavirus OC43.
Bioorganic & medicinal chemistry letters.
2023 03; 84(?):129211. doi:
10.1016/j.bmcl.2023.129211
. [PMID: 36863494] - Rui Li, Baskaran Stephen Inbaraj, Bing-Huei Chen. Quantification of Xanthone and Anthocyanin in Mangosteen Peel by UPLC-MS/MS and Preparation of Nanoemulsions for Studying Their Inhibition Effects on Liver Cancer Cells.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043934
. [PMID: 36835343] - Tusheema Dutta, Tuyelee Das, Abilash Valsala Gopalakrishnan, Suchismita Chatterjee Saha, Mimosa Ghorai, Samapika Nandy, Manoj Kumar, Radha, Arabinda Ghosh, Nobendu Mukerjee, Abhijit Dey. Mangiferin: the miraculous xanthone with diverse pharmacological properties.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Jan; ?(?):. doi:
10.1007/s00210-022-02373-6
. [PMID: 36656353] - İhsan Çalış, Ayşe Ünlü, Zübeyde Uğurlu Aydın, Ali A Dönmez, Hasan Soliman Yusufoğlu, Simon Jurt, Anthony Linden. Xanthones and Xanthone O-β-D-Glucosides from the Roots of Polygala azizsancarii Dönmez.
Chemistry & biodiversity.
2022 Aug; 19(8):e202200499. doi:
10.1002/cbdv.202200499
. [PMID: 35797203] - Amira R Khattab, Mohamed A Farag. Marine and terrestrial endophytic fungi: a mine of bioactive xanthone compounds, recent progress, limitations, and novel applications.
Critical reviews in biotechnology.
2022 May; 42(3):403-430. doi:
10.1080/07388551.2021.1940087
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Natural product research.
2022 Apr; 36(8):2071-2077. doi:
10.1080/14786419.2020.1845674
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Molecules (Basel, Switzerland).
2021 Dec; 27(1):. doi:
10.3390/molecules27010003
. [PMID: 35011235] - Qing Huang, Youyi Wang, Huaimo Wu, Man Yuan, Changwu Zheng, Hongxi Xu. Xanthone Glucosides: Isolation, Bioactivity and Synthesis.
Molecules (Basel, Switzerland).
2021 Sep; 26(18):. doi:
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Scientific reports.
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Life sciences.
2021 Jun; 275(?):119387. doi:
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10.1111/tpj.15012
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2020 Dec; 35(1):1433-1441. doi:
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International journal of molecular sciences.
2020 Sep; 21(17):. doi:
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International journal of molecular sciences.
2020 Jul; 21(14):. doi:
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The Kaohsiung journal of medical sciences.
2020 Jul; 36(7):523-534. doi:
10.1002/kjm2.12205
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Critical reviews in biotechnology.
2020 May; 40(3):415-431. doi:
10.1080/07388551.2020.1721426
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Fitoterapia.
2020 Mar; 141(?):104449. doi:
10.1016/j.fitote.2019.104449
. [PMID: 31816345] - Anna Dalinova, Leonid Chisty, Dmitry Kochura, Varvara Garnyuk, Maria Petrova, Darya Prokofieva, Anton Yurchenko, Vsevolod Dubovik, Alexander Ivanov, Sergey Smirnov, Andrey Zolotarev, Alexander Berestetskiy. Isolation and Bioactivity of Secondary Metabolites from Solid Culture of the Fungus, Alternaria sonchi.
Biomolecules.
2020 01; 10(1):. doi:
10.3390/biom10010081
. [PMID: 31947939] - Aye Aye, Young-Jae Song, Yong-Deok Jeon, Jong-Sik Jin. Xanthone suppresses allergic contact dermatitis in vitro and in vivo.
International immunopharmacology.
2020 Jan; 78(?):106061. doi:
10.1016/j.intimp.2019.106061
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Dec; 120(?):109439. doi:
10.1016/j.biopha.2019.109439
. [PMID: 31590126] - Neil Miller, Stephanie C Bosman, Christiaan J Malherbe, Dalene De Beer, Elizabeth Joubert. Membrane selection and optimisation of tangential flow ultrafiltration of Cyclopia genistoides extract for benzophenone and xanthone enrichment.
Food chemistry.
2019 Sep; 292(?):121-128. doi:
10.1016/j.foodchem.2019.04.047
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Journal of pharmaceutical and biomedical analysis.
2019 Feb; 164(?):302-308. doi:
10.1016/j.jpba.2018.10.054
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Chemistry & biodiversity.
2019 Feb; 16(2):e1800509. doi:
10.1002/cbdv.201800509
. [PMID: 30511810] - Lara Alexander, Dalene de Beer, Magdalena Muller, Marieta van der Rijst, Elizabeth Joubert. Impact of steam treatment on shelf-life stability of a xanthone-rich green herbal tea (Cyclopia maculata Andrews Kies) - identifying quality changes during storage.
Journal of the science of food and agriculture.
2019 Feb; 99(3):1334-1341. doi:
10.1002/jsfa.9308
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Applied microbiology and biotechnology.
2019 Feb; 103(3):1363-1377. doi:
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Fitoterapia.
2019 Jan; 132(?):22-25. doi:
10.1016/j.fitote.2018.07.014
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Plant cell reports.
2018 Nov; 37(11):1471-1484. doi:
10.1007/s00299-018-2317-2
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Food & function.
2018 Jul; 9(7):3860-3871. doi:
10.1039/c8fo00439k
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Food & function.
2018 Jun; 9(6):3291-3300. doi:
10.1039/c8fo00378e
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European journal of medicinal chemistry.
2018 May; 151(?):272-284. doi:
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Journal of natural products.
2018 04; 81(4):749-757. doi:
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2018 04; 28(6):1063-1066. doi:
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2018 02; 217(3):1099-1112. doi:
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Journal of pharmaceutical and biomedical analysis.
2018 Jan; 148(?):298-306. doi:
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2017 Nov; 31(21):2513-2519. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 May; 89(?):342-350. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2017 Apr; 27(?):8-14. doi:
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European journal of drug metabolism and pharmacokinetics.
2016 Oct; 41(5):605-13. doi:
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Molecules (Basel, Switzerland).
2016 Jun; 21(6):. doi:
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Plant cell reports.
2016 May; 35(5):1009-20. doi:
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Biomedical chromatography : BMC.
2016 Apr; 30(4):508-19. doi:
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2015 Nov; 10(11):1969-72. doi:
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Plant cell reports.
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Applied microbiology and biotechnology.
2015 Sep; 99(18):7399-415. doi:
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AAPS PharmSciTech.
2015 Apr; 16(2):250-8. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2015 Apr; 40(7):1342-6. doi:
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Chemistry & biodiversity.
2015 Mar; 12(3):358-70. doi:
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Journal of cellular physiology.
2014 Dec; 229(12):1972-80. doi:
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Pharmaceutical biology.
2014 Nov; 52(11):1367-73. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2014 Nov; 49(?):155-61. doi:
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Medical hypotheses.
2014 Nov; 83(5):570-4. doi:
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Journal of agricultural and food chemistry.
2014 Oct; 62(43):10542-51. doi:
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The journal of physical chemistry. B.
2014 Oct; 118(41):11993-2001. doi:
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Natural product communications.
2014 Oct; 9(10):1487-9. doi:
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Molecules (Basel, Switzerland).
2014 Aug; 19(8):11760-90. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2014 Aug; 70(?):151-6. doi:
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Chinese journal of natural medicines.
2014 Jul; 12(7):525-34. doi:
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Molecules (Basel, Switzerland).
2014 Jun; 19(6):7308-16. doi:
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Interdisciplinary sciences, computational life sciences.
2014 Jun; 6(2):125-32. doi:
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Planta medica.
2014 Jun; 80(8-9):676-81. doi:
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Bioorganic & medicinal chemistry.
2014 May; 22(9):2671-7. doi:
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Molecules (Basel, Switzerland).
2014 Feb; 19(2):1820-7. doi:
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2014 Feb; 97 Suppl 2(?):S196-201. doi:
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Molecules (Basel, Switzerland).
2013 Dec; 18(12):15305-13. doi:
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Journal of pharmaceutical and biomedical analysis.
2013 Nov; 85(?):1-13. doi:
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Steroids.
2013 Nov; 78(11):1053-63. doi:
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2013 Sep; 36(9):1444-7. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2013 Mar; 20(5):401-8. doi:
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Molecular nutrition & food research.
2013 Feb; 57(2):203-11. doi:
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Natural product research.
2013; 27(6):563-7. doi:
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2012 Dec; 37(24):3734-7. doi:
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Journal of natural products.
2012 Sep; 75(9):1660-4. doi:
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Planta medica.
2012 Sep; 78(14):1591-6. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2012 Aug; 19(11):1007-15. doi:
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Phytochemistry.
2012 Aug; 80(?):58-63. doi:
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Plant physiology and biochemistry : PPB.
2012 Aug; 57(?):54-8. doi:
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World journal of gastroenterology.
2012 Jul; 18(25):3207-14. doi:
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Journal of clinical biochemistry and nutrition.
2012 May; 50(3):199-204. doi:
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Toxicology and applied pharmacology.
2012 Apr; 260(1):35-47. doi:
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Pharmaceutical biology.
2012 Apr; 50(4):453-7. doi:
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Journal of pharmaceutical and biomedical analysis.
2012 Mar; 62(?):228-34. doi:
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Molecules (Basel, Switzerland).
2012 Mar; 17(3):2833-54. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2012 Feb; 19(3-4):374-7. doi:
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Free radical research.
2012 Feb; 46(2):116-32. doi:
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PloS one.
2012; 7(3):e33376. doi:
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Cancer research.
2012 Jan; 72(1):260-70. doi:
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PloS one.
2012; 7(1):e30782. doi:
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Journal of biomedicine & biotechnology.
2012; 2012(?):672428. doi:
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International journal of peptides.
2012; 2012(?):256294. doi:
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PloS one.
2012; 7(1):e28737. doi:
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Pharmacological reports : PR.
2012; 64(4):848-56. doi:
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Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):867103. doi:
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Biochemical pharmacology.
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