1,5-Naphthalene diisocyanate (BioDeep_00000002743)

 

Secondary id: BioDeep_00001868563

human metabolite blood metabolite


代谢物信息卡片


1,5-Naphthylene di-isocyanate

化学式: C12H6N2O2 (210.04292560000002)
中文名称: 1,5-二异氰酸萘
谱图信息: 最多检出来源 Homo sapiens(blood) 96.43%

分子结构信息

SMILES: C1=CC2=C(C=CC=C2N=C=O)C(=C1)N=C=O
InChI: InChI=1S/C12H6N2O2/c15-7-13-11-5-1-3-9-10(11)4-2-6-12(9)14-8-16/h1-6H

描述信息

同义名列表

3 个代谢物同义名

1,5-Naphthylene di-isocyanate; 1,5-Naphthalene diisocyanate; 1,5-Diisocyanatonaphthalene



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ovnair Sepai, Gabriele Sabbioni. Albumin adducts and urinary metabolites resulting from occupational exposure to 1,5-naphthalene diisocyanate. International journal of occupational medicine and environmental health. 2017 Jun; 30(4):579-591. doi: 10.13075/ijomeh.1896.00863. [PMID: 28584318]
  • Håkan Tinnerberg, Karin Broberg, Christian H Lindh, Bo A G Jönsson. Biomarkers of exposure in Monday morning urine samples as a long-term measure of exposure to aromatic diisocyanates. International archives of occupational and environmental health. 2014 May; 87(4):365-72. doi: 10.1007/s00420-013-0872-y. [PMID: 23558852]
  • Lygia T Budnik, Dennis Nowak, Rolf Merget, Catherine Lemiere, Xaver Baur. Elimination kinetics of diisocyanates after specific inhalative challenges in humans: mass spectrometry analysis, as a basis for biomonitoring strategies. Journal of occupational medicine and toxicology (London, England). 2011 Mar; 6(1):9. doi: 10.1186/1745-6673-6-9. [PMID: 21447151]
  • C J Sennbro, C H Lindh, C Mattsson, B A G Jönsson, H Tinnerberg. Biological monitoring of exposure to 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate. International archives of occupational and environmental health. 2006 Sep; 79(8):647-53. doi: 10.1007/s00420-006-0096-5. [PMID: 16506043]
  • Carl Johan Sennbro, Margareta Littorin, Håkan Tinnerberg, Bo A G Jönsson. Upper reference limits for biomarkers of exposure to aromatic diisocyanates. International archives of occupational and environmental health. 2005 Aug; 78(7):541-6. doi: 10.1007/s00420-005-0619-5. [PMID: 15995877]
  • Carl Johan Sennbro, Christian H Lindh, Håkan Tinnerberg, Cecilia Gustavsson, Margareta Littorin, Hans Welinder, Bo A G Jönsson. Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2003 May; 8(3-4):204-17. doi: 10.1080/1354750031000090660. [PMID: 12944173]
  • R Merget, B Marczynski, Z Chen, K Remberger, M Raulf-Heimsoth, P O Willrot, X Baur. Haemorrhagic hypersensitivity pneumonitis due to naphthylene-1,5-diisocyanate. The European respiratory journal. 2002 Feb; 19(2):377-80. doi: 10.1183/09031936.02.00244702. [PMID: 11866019]
  • R Alexandersson, P Gustafsson, G Hedenstierna, G Rosen. Exposure to naphthalene-diisocyanate in a rubber plant: symptoms and lung function. Archives of environmental health. 1986 Mar; 41(2):85-9. doi: 10.1080/00039896.1986.9937414. [PMID: 3718007]