S-Allylmercapturic acid (BioDeep_00000272657)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2R)-2-ACETAMIDO-3-(PROP-2-EN-1-YLSULFANYL)PROPANOIC ACID

化学式: C8H13NO3S (203.0616)
中文名称: N-acetyl-S-allylcysteine
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 67.47%

分子结构信息

SMILES: C=CCSCC(NC(C)=O)C(=O)O
InChI: InChI=1S/C8H13NO3S/c1-3-4-13-5-7(8(11)12)9-6(2)10/h3,7H,1,4-5H2,2H3,(H,9,10)(H,11,12)/t7-/m0/s1

描述信息

N-acetyl-S-allylcysteine is a N-acyl-L-amino acid.

同义名列表

12 个代谢物同义名

(2R)-2-ACETAMIDO-3-(PROP-2-EN-1-YLSULFANYL)PROPANOIC ACID; (2R)-2-acetamido-3-prop-2-enylsulfanylpropanoic acid; (2R)-2-acetamido-3-prop-2-enylsulanylpropanoic acid; N-(1-Hydroxyethylidene)-S-prop-2-en-1-ylcysteine; (R)-2-Acetamido-3-(allylthio)propanoic acid; L-Cysteine, N-acetyl-S-2-propen-1-yl-; N-Acetyl-S-2-propen-1-yl-L-cysteine; L-Cysteine, N-acetyl-S-2-propenyl-; L-N-Acetyl-3-(allylthio)alanine; N-Acetyl-S-allyl-L-cysteine; N-acetyl-S-allylcysteine; S-Allylmercapturic acid



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Hirotaka Amano, Daichi Kazamori, Kenji Itoh. Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption. The Journal of nutrition. 2016 Feb; 146(2):456S-459S. doi: 10.3945/jn.114.201749. [PMID: 26764325]
  • Hirotaka Amano, Daichi Kazamori, Kenji Itoh, Yukihiro Kodera. Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs. Drug metabolism and disposition: the biological fate of chemicals. 2015 May; 43(5):749-55. doi: 10.1124/dmd.115.063230. [PMID: 25681129]
  • Keary Cope, Harold Seifried, Rebecca Seifried, John Milner, Penny Kris-Etherton, Earl H Harrison. A gas chromatography-mass spectrometry method for the quantitation of N-nitrosoproline and N-acetyl-S-allylcysteine in human urine: application to a study of the effects of garlic consumption on nitrosation. Analytical biochemistry. 2009 Nov; 394(2):243-8. doi: 10.1016/j.ab.2009.07.035. [PMID: 19643074]
  • M Padmanabhan, P Stanely Mainzen Prince. Preventive effect of S-allylcysteine on lipid peroxides and antioxidants in normal and isoproterenol-induced cardiotoxicity in rats: a histopathological study. Toxicology. 2006 Jul; 224(1-2):128-37. doi: 10.1016/j.tox.2006.04.039. [PMID: 16757080]
  • José Pedraza-Chaverrí, Mariana Gil-Ortiz, Gabriela Albarrán, Laura Barbachano-Esparza, Marta Menjívar, Omar N Medina-Campos. Garlic's ability to prevent in vitro Cu2+-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu2+-chelation. Nutrition journal. 2004 Sep; 3(?):10. doi: 10.1186/1475-2891-3-10. [PMID: 15341661]
  • Renee J Krause, Lawrence H Lash, Adnan A Elfarra. Human kidney flavin-containing monooxygenases and their potential roles in cysteine s-conjugate metabolism and nephrotoxicity. The Journal of pharmacology and experimental therapeutics. 2003 Jan; 304(1):185-91. doi: 10.1124/jpet.102.042911. [PMID: 12490590]
  • Renee J Krause, Steven C Glocke, Adnan A Elfarra. Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases. Drug metabolism and disposition: the biological fate of chemicals. 2002 Oct; 30(10):1137-42. doi: 10.1124/dmd.30.10.1137. [PMID: 12228191]
  • J M Pombrio, A Giangreco, L Li, M F Wempe, M W Anders, D H Sweet, J B Pritchard, N Ballatori. Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. Molecular pharmacology. 2001 Nov; 60(5):1091-9. doi: 10.1124/mol.60.5.1091. [PMID: 11641438]
  • H Verhagen, G J Hageman, A L Rauma, G Versluis-de Haan, M H van Herwijnen, J de Groot, R Törrönen, H Mykkänen. Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid. The British journal of nutrition. 2001 Aug; 86 Suppl 1(?):S111-4. doi: 10.1079/bjn2001343. [PMID: 11520428]
  • B M de Rooij, J N Commandeur, E J Groot, P J Boogaard, N P Vermeulen. Biotransformation of allyl chloride in the rat. Influence of inducers on the urinary metabolic profile. Drug metabolism and disposition: the biological fate of chemicals. 1996 Jul; 24(7):765-72. doi: NULL. [PMID: 8818574]
  • J Jandke, G Spiteller. Unusual conjugates in biological profiles originating from consumption of onions and garlic. Journal of chromatography. 1987 Oct; 421(1):1-8. doi: 10.1016/0378-4347(87)80373-0. [PMID: 3429558]