Bromocriptine (BioDeep_00000002707)

 

Secondary id: BioDeep_00000408892

human metabolite blood metabolite


代谢物信息卡片


(4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0²,⁶]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide

化学式: C32H40BrN5O5 (653.221265)
中文名称: 溴隐亭
谱图信息: 最多检出来源 Homo sapiens(blood) 98.48%

分子结构信息

SMILES: CC(C)CC1C(=O)N2CCCC2C2(O)OC(NC(=O)C3C=C4c5cccc6[nH]c(Br)c(c56)CC4N(C)C3)(C(C)C)C(=O)N12
InChI: InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1

描述信息

Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It is indicated for the management of signs and symptoms of Parkinsonian Syndrome. Bromocriptine also inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. It also causes sustained suppression of somatotropin (growth hormone) secretion in some patients with acromegaly. Bromocriptine has been associated with pulmonary fibrosis.
G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02C - Other gynecologicals > G02CB - Prolactine inhibitors
D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents
N - Nervous system > N04 - Anti-parkinson drugs > N04B - Dopaminergic agents > N04BC - Dopamine agonists
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
C78272 - Agent Affecting Nervous System > C66884 - Dopamine Agonist
C26170 - Protective Agent > C1509 - Neuroprotective Agent

同义名列表

44 个代谢物同义名

(4R,7R)-10-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-(propan-2-yl)-3-oxa-6,9-diazatricyclo[7.3.0.0²,⁶]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaene-4-carboxamide; (5alpha)-2-Bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6,18-trioxoergotaman; (5alpha)-2-Bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)ergotaman-3,6,18-trione; (5a)-2-Bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)ergotaman-3,6,18-trione; (5a)-2-Bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6,18-trioxoergotaman; (5Α)-2-bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6,18-trioxoergotaman; (5Α)-2-bromo-12-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)ergotaman-3,6,18-trione; (5alpha)-2-Bromo-12-hydroxy-5-isobutyl-2-isopropyl-3,6,18-trioxoergotaman; (5Α)-2-bromo-12-hydroxy-5-isobutyl-2-isopropyl-3,6,18-trioxoergotaman; (5a)-2-Bromo-12-hydroxy-5-isobutyl-2-isopropyl-3,6,18-trioxoergotaman; Methanesulfonate, 2-bromoergocryptine; 2 Bromoergocryptine methanesulfonate; 2-Bromoergocryptine methanesulfonate; Bromocriptine methanesulfonate; Mesylate, 2-bromoergocryptine; 2-Bromoergocryptine mesylate; 2 Bromoergocryptine mesylate; 2 Bromo alpha ergocryptine; 2-Bromo-alpha-ergocryptine; 2-Bromo-alpha-ergokryptine; 2 Bromo alpha ergokryptine; 2-Bromo-alpha-ergokryptin; Mesylate, bromocriptine; 2-Bromo-α-ergokryptine; 2-Bromo-α-ergocryptine; Bromocriptine mesylate; 2-Bromo-a-ergokryptine; 2-Bromo-a-ergocryptine; 2-Bromo-α-ergokryptin; 2-Bromo-a-ergokryptin; 2-Bromoergokryptine; 2 Bromoergokryptine; 2 Bromoergocryptine; 2-Bromoergocryptine; Bromoergocryptine; Bromoergocriptine; Bromergocryptine; Bromocriptinum; Bromocriptine; Bromocryptine; Bromocriptin; Bromocryptin; LSM-1746; Parlodel



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Milica Vranic, Fozia Ahmed, Robin Kristófi, Susanne Hetty, Dariush Mokhtari, Maria K Svensson, Jan W Eriksson, Maria J Pereira. Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D. Endocrine. 2023 Sep; ?(?):. doi: 10.1007/s12020-023-03525-1. [PMID: 37752366]
  • Shang Guo, Nannan Qin, Xiuying Wang, Zanwen Zuo, Qizhang Li, Yuliang Wang. Freeze-dried powder of daylily bud improves bromocriptine-induced lactation disorder in rats via JAK2/STAT5 pathway. Journal of ethnopharmacology. 2023 Apr; 313(?):116536. doi: 10.1016/j.jep.2023.116536. [PMID: 37120059]
  • Víctor H Castillo-Campohermoso, Luz M Molina-Martínez, Eliana Barrios de Tomasi, Jorge Juárez. Co-administration of bromocriptine and corticosterone produces short- and long-lasting reduction in intake of high-fat food in male rats. Behavioural pharmacology. 2023 02; 34(1):1-11. doi: 10.1097/fbp.0000000000000706. [PMID: 36730784]
  • Sandip Debnath, Devesh Sharma, Somdatta Yashwant Chaudhari, Ritika Sharma, Amir Afzal Shaikh, Rahul Subhash Buchade, Kavindra Kumar Kesari, Abdel-Fattah M Abdel-Fattah, Mohammad Algahtani, Mayyadah Mheidat, Rawidh Alsaidalani, Tapas Paul, Amany A Sayed, Mohamed M Abdel-Daim. Wheat ergot fungus-derived and modified drug for inhibition of intracranial aneurysm rupture due to dysfunction of TLR-4 receptor in Alzheimer's disease. PloS one. 2023; 18(1):e0279616. doi: 10.1371/journal.pone.0279616. [PMID: 36656815]
  • Tomohito Mizuno, Riku Takahashi, Takahiro Kamiyama, Atsushi Suzuki, Masashi Suzuki. Neuroleptic Malignant Syndrome with Adrenal Insufficiency After BNT162b2 COVID-19 Vaccination in a Man Taking Valproate: A Case Report. The American journal of case reports. 2022 May; 23(?):e936217. doi: 10.12659/ajcr.936217. [PMID: 35514081]
  • Muhammad Usama Ashhar, Preeti Vyas, Divya Vohora, Pravat Kumar Sahoo, Kuldeep Nigam, Shweta Dang, Javed Ali, Sanjula Baboota. Amelioration of oxidative stress utilizing nanoemulsion loaded with bromocriptine and glutathione for the management of Parkinson's disease. International journal of pharmaceutics. 2022 Apr; 618(?):121683. doi: 10.1016/j.ijpharm.2022.121683. [PMID: 35314276]
  • Shinnosuke Masuda, Oh Kwan Ee, Taku James Sairenji, Seika Sato, Hiroyuki Yajima, Izuki Amano, Noriyuki Koibuchi, Noriaki Shimokawa. Maternal prolactin levels during late pregnancy and nurturing behavior of offspring in mice. Developmental psychobiology. 2022 03; 64(3):e22264. doi: 10.1002/dev.22264. [PMID: 35312052]
  • Zain Ul-Abideen, Hafiz Ishfaq Ahmad, Muhammad Nadeem, Aleem Ahmad Khan, Muhammad Imran, Tanveer Majeed, Shouqun Jiang, Abdelmotaleb Elokil. The therapeutic effect of bromocriptine as mesylate and estradiol valerate on serum and blood biochemistry of common quails. Poultry science. 2022 Feb; 101(2):101552. doi: 10.1016/j.psj.2021.101552. [PMID: 34942520]
  • Bianca N Mason, Rohini Kallianpur, Theodore J Price, Armen N Akopian, Gregory O Dussor. Prolactin signaling modulates stress-induced behavioral responses in a preclinical mouse model of migraine. Headache. 2022 Jan; 62(1):11-25. doi: 10.1111/head.14248. [PMID: 34967003]
  • Rosa Pirchio, Chiara Graziadio, Annamaria Colao, Rosario Pivonello, Renata S Auriemma. Metabolic effects of prolactin. Frontiers in endocrinology. 2022; 13(?):1015520. doi: 10.3389/fendo.2022.1015520. [PMID: 36237192]
  • Hua Feng, Qiuxi Zhong, Huifang Zhou, Xiaoyue Jiang, Yinyin Ding. The effects of combined bromocriptine and Bu-shen-zhu-yun decoction on serum hormones, anxiety, and pregnancy in hyperprolactinemic infertility patients. Annals of palliative medicine. 2021 Dec; 10(12):12230-12243. doi: 10.21037/apm-21-3111. [PMID: 35016475]
  • Merve Yuce, Erdem Cicek, Tugce Inan, Aslihan Basak Dag, Ozge Kurkcuoglu, Fethiye Aylin Sungur. Repurposing of FDA-approved drugs against active site and potential allosteric drug-binding sites of COVID-19 main protease. Proteins. 2021 11; 89(11):1425-1441. doi: 10.1002/prot.26164. [PMID: 34169568]
  • Mohammed Ahmed Fouad Shalaby, Hekma A Abd El Latif, Mohamed El Yamani, May Ahmed Galal, Sherifa Kamal, Ikhlas Sindi, Raneem Masaood. Therapeutic activity of sarpogrelate and dopamine D2 receptor agonists on cardiovascular and renal systems in rats with alloxan-induced diabetes. BMC pharmacology & toxicology. 2021 10; 22(1):64. doi: 10.1186/s40360-021-00526-6. [PMID: 34702339]
  • G Tavares, D Marques, C Barra, D Rosendo-Silva, A Costa, T Rodrigues, P Gasparini, B F Melo, J F Sacramento, R Seiça, S V Conde, P Matafome. Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes. Molecular metabolism. 2021 09; 51(?):101241. doi: 10.1016/j.molmet.2021.101241. [PMID: 33933677]
  • Michael Ezrokhi, Yahong Zhang, Shuqin Luo, Anthony H Cincotta. Time-of-Day-Dependent Effects of Bromocriptine to Ameliorate Vascular Pathology and Metabolic Syndrome in SHR Rats Held on High Fat Diet. International journal of molecular sciences. 2021 Jun; 22(11):. doi: 10.3390/ijms22116142. [PMID: 34200262]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Maria Camila Moreno-Escobar, Saurabh Kataria, Erum Khan, Roshan Subedi, Medha Tandon, Krithika Peshwe, Joshua Kramer, Faraze Niaze, Shitiz Sriwastava. Acute transverse myelitis with Dysautonomia following SARS-CoV-2 infection: A case report and review of literature. Journal of neuroimmunology. 2021 04; 353(?):577523. doi: 10.1016/j.jneuroim.2021.577523. [PMID: 33640717]
  • Motoyuki Igata, Yoshitaka Yagi, Satoko Hanatani, Masaji Sakaguchi, Norio Ishii, Kayo Yoshinaga, Junji Kawashima, Hiroyuki Motoshima, Eiichi Araki. Rapid and dramatic glucose-lowering effect of bromocriptine in an inadequately controlled type 2 diabetes patient with prolactinoma. Journal of diabetes investigation. 2021 Apr; 12(4):668-671. doi: 10.1111/jdi.13369. [PMID: 32706496]
  • Iala Milene Bertasso, Carla Bruna Pietrobon, Beatriz Souza da Silva, Rosiane Aparecida Miranda, Maria Lucia Bonfleur, Sandra Lucinei Balbo, Alex Christian Manhães, Elaine Oliveira, Egberto Gaspar de Moura, Patricia Cristina Lisboa. Hepatic lipid metabolism in adult rats using early weaning models: sex-related differences. Journal of developmental origins of health and disease. 2020 10; 11(5):499-508. doi: 10.1017/s2040174420000495. [PMID: 32519629]
  • Jie Yin, Kuang-Yui M Chen, Mary J Clark, Mahdi Hijazi, Punita Kumari, Xiao-Chen Bai, Roger K Sunahara, Patrick Barth, Daniel M Rosenbaum. Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature. 2020 08; 584(7819):125-129. doi: 10.1038/s41586-020-2379-5. [PMID: 32528175]
  • Raahil Kajani, Austin Apramian, Arturo Vega, Nitin Ubhayakar, Prissilla Xu, Antonio Liu. Neuroleptic malignant syndrome in a COVID-19 patient. Brain, behavior, and immunity. 2020 08; 88(?):28-29. doi: 10.1016/j.bbi.2020.05.042. [PMID: 32425332]
  • Carla Bruna Pietrobon, Iala Milene Bertasso, Beatrix S Silva, Nayara Peixoto-Silva, Elaine Oliveira, Egberto Gaspar Moura, Patricia Cristina Lisboa. Body Adiposity and Endocrine Profile of Female Wistar Rats of Distinct Ages that were Early Weaned. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2020 Jan; 52(1):58-66. doi: 10.1055/a-0966-8784. [PMID: 31537024]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Tamami Oshige, Yui Nakamura, Yuko Sasaki, Seiko Kawano, Tsuyoshi Ohki, Munehisa Tsuruta, Ichiro Tokubuchi, Hitomi Nakayama, Kentaro Yamada, Kenji Ashida, Yuji Tajiri, Masatoshi Nomura. Bromocriptine as a Potential Glucose-lowering Agent for the Treatment of Prolactinoma with Type 2 Diabetes. Internal medicine (Tokyo, Japan). 2019 Nov; 58(21):3125-3128. doi: 10.2169/internalmedicine.2755-19. [PMID: 31243214]
  • Robert Krysiak, Bogusław Okopień. Sexual Functioning in Hyperprolactinemic Patients Treated With Cabergoline or Bromocriptine. American journal of therapeutics. 2019 Jul; 26(4):e433-e440. doi: 10.1097/mjt.0000000000000777. [PMID: 29746287]
  • Ana Velosa, António Neves, J Bernardo Barahona-Corrêa, Albino J Oliveira-Maia. Neuroleptic malignant syndrome: a concealed diagnosis with multitreatment approach. BMJ case reports. 2019 Jun; 12(6):. doi: 10.1136/bcr-2018-225840. [PMID: 31213433]
  • Kosuke Mukai, Michio Otsuki, Daisuke Tamada, Tetsuhiro Kitamura, Reiko Hayashi, Aya Saiki, Yuko Goto, Hideyuki Arita, Satoru Oshino, Eiichi Morii, Youichi Saitoh, Iichiro Shimomura. Clinical Characteristics of Acromegalic Patients With Paradoxical GH Response to Oral Glucose Load. The Journal of clinical endocrinology and metabolism. 2019 05; 104(5):1637-1644. doi: 10.1210/jc.2018-00975. [PMID: 30476255]
  • Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Different effects of fenofibrate on cardiometabolic risk factors in young women with and without hyperprolactinemia. Pharmacological reports : PR. 2019 Feb; 71(1):61-66. doi: 10.1016/j.pharep.2018.09.004. [PMID: 30469130]
  • Isadora C Furigo, Miriam F Suzuki, João E Oliveira, Angela M Ramos-Lobo, Pryscila D S Teixeira, João A Pedroso, Amanda de Alencar, Thais T Zampieri, Daniella C Buonfiglio, Paula G F Quaresma, Patricia O Prada, Paolo Bartolini, Carlos R J Soares, Jose Donato. Suppression of Prolactin Secretion Partially Explains the Antidiabetic Effect of Bromocriptine in ob/ob Mice. Endocrinology. 2019 01; 160(1):193-204. doi: 10.1210/en.2018-00629. [PMID: 30462197]
  • Jun Gao, Yang Liu, Gaijing Han, Kan Deng, Xiaohai Liu, Xinjie Bao, Ming Feng, Yong Yao, Wei Lian, Bing Xing, Xiang Lv, Renzhi Wang. Metformin inhibits growth and prolactin secretion of pituitary prolactinoma cells and xenografts. Journal of cellular and molecular medicine. 2018 12; 22(12):6368-6379. doi: 10.1111/jcmm.13963. [PMID: 30334324]
  • Mohamed Soliman, Fathia M Khattab, Howyda Mohamed Ebrahim, Mohamad Nasr. Serum prolactin level in chronic urticaria: Is bromocriptine inducing remission in chronic urticaria?. The Journal of dermatological treatment. 2018 Dec; 29(8):826-830. doi: 10.1080/09546634.2018.1468062. [PMID: 29694255]
  • Suresh Palle, Prasad Neerati. Quercetin nanoparticles alter pharmacokinetics of bromocriptine, reflecting its enhanced inhibitory action on liver and intestinal CYP 3A enzymes in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2018 Oct; 48(10):1028-1036. doi: 10.1080/00498254.2017.1390277. [PMID: 28990837]
  • Ana C L Camargo, Flávia B Constantino, Sérgio A A Santos, Ketlin T Colombelli, Maeli Dal-Pai-Silva, Sérgio L Felisbino, Luis A Justulin. Influence of postnatal prolactin modulation on the development and maturation of ventral prostate in young rats. Reproduction, fertility, and development. 2018 Jun; 30(7):969-979. doi: 10.1071/rd17343. [PMID: 29207253]
  • Hai Yan Huang, Shao Jian Lin, Wei Guo Zhao, Zhe Bao Wu. Cabergoline versus bromocriptine for the treatment of giant prolactinomas: A quantitative and systematic review. Metabolic brain disease. 2018 06; 33(3):969-976. doi: 10.1007/s11011-018-0217-3. [PMID: 29546691]
  • Xia Zhou, Liying Ren, Zhiling Yu, Xiaoqian Huang, Yuhao Li, Chunxia Wang. The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance. Toxicology and applied pharmacology. 2018 04; 345(?):66-74. doi: 10.1016/j.taap.2018.02.023. [PMID: 29551354]
  • Chengxian Yang, Huanwen Wu, Jing Wang, Mingming Hu, Xiaoping Xing, Xinjie Bao, Renzhi Wang. Successful management of octreotide-insensitive thyrotropin-secreting pituitary adenoma with bromocriptine and surgery: A case report and literature review. Medicine. 2017 Sep; 96(36):e8017. doi: 10.1097/md.0000000000008017. [PMID: 28885368]
  • Margarida Teixeira, Pedro Souteiro, Davide Carvalho. Prolactinoma management: predictors of remission and recurrence after dopamine agonists withdrawal. Pituitary. 2017 Aug; 20(4):464-470. doi: 10.1007/s11102-017-0806-x. [PMID: 28523537]
  • Robert Krysiak, Witold Szkróbka, Bogusław Okopień. Alternative Treatment Strategies in Women Poorly Tolerating Moderate Doses of Bromocriptine. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 2017 Jun; 125(6):360-364. doi: 10.1055/s-0042-123041. [PMID: 28073129]
  • Bindu Chamarthi, Anthony H Cincotta. Effect of bromocriptine-QR therapy on glycemic control in subjects with type 2 diabetes mellitus whose dysglycemia is inadequately controlled on insulin. Postgraduate medicine. 2017 May; 129(4):446-455. doi: 10.1080/00325481.2017.1315290. [PMID: 28374645]
  • Oliva Mejía-Rodríguez, Humberto Ruiz-Vega, Cleto Álvarez-Aguilar, Marcela Ávila-Díaz, Silvia Palomo-Piñón, José Ramón Paniagua-Sierra. Blood pressure rhythmicity in patients with end stage chronic kidney disease: bromocriptine effect. Revista medica del Instituto Mexicano del Seguro Social. 2017; 55(Suppl 2):S182-7. doi: NULL. [PMID: 29697240]
  • K V Derkach, A O Ivantsov, I B Sukhov, A O Shpakov. THE RESTORATION OF HYPOTHALAMIC SIGNALING SYSTEMS AS ONE OF THE CAUSES TO IMPROVE THE METABOLIC PARAMETERS IN BROMOCRYPTINE-TREATED RATS WITH NEONATAL MODEL OF DIABETES MELLITUS. Tsitologiia. 2017 ; 59(2):140-7. doi: . [PMID: 30199162]
  • Janaine C Carvalho, Patricia C Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Jessica L Nobre, Mabel C Fraga, Alex C Manhães, Egberto G Moura. Effects of postnatal bromocriptine injection on thyroid function and prolactinemia of rats at adulthood. Neuropeptides. 2016 Oct; 59(?):71-81. doi: 10.1016/j.npep.2016.05.003. [PMID: 27261099]
  • Xiaojing Chen, Xiaoqing Yang, Rongrong Wu, Weiwei Chen, Huihui Xie, Xia Qian, Yuquan Zhang. Therapeutic effects of Wharton jelly-derived mesenchymal stem cells on rat abortion models. The journal of obstetrics and gynaecology research. 2016 Aug; 42(8):972-82. doi: 10.1111/jog.12984. [PMID: 27147487]
  • Hengxi Chen, Jing Fu, Wei Huang. Dopamine agonists for preventing future miscarriage in women with idiopathic hyperprolactinemia and recurrent miscarriage history. The Cochrane database of systematic reviews. 2016 Jul; 7(?):CD008883. doi: 10.1002/14651858.cd008883.pub2. [PMID: 27455388]
  • Janaine C Carvalho, Patricia C Lisboa, Elaine de Oliveira, Nayara Peixoto-Silva, Cintia R Pinheiro, Mabel C Fraga, Sylvio Claudio-Neto, Celso R Franci, Alex C Manhães, Egberto G Moura. Effects of early and late neonatal bromocriptine treatment on hypothalamic neuropeptides, dopaminergic reward system and behavior of adult rats. Neuroscience. 2016 06; 325(?):175-87. doi: 10.1016/j.neuroscience.2016.03.046. [PMID: 27038750]
  • Yu Pan, Jing Lv, Rui Guo, Mengyi Pan, Yifan Zhang. Pituitary Prolactinoma Imaged by 99mTc-Sestamibi SPECT/CT in a Multiple Endocrine Neoplasia Type 1 Patient. Clinical nuclear medicine. 2016 Jun; 41(6):497-9. doi: 10.1097/rlu.0000000000001144. [PMID: 26828146]
  • Robert Krysiak, Joanna Okrzesik, Witold Szkrobka, Bogusław Okopień. The effect of fenofibrate on cardiometabolic risk factors in bromocriptine-treated women with mixed dyslipidemia: A pilot study. Pharmacological reports : PR. 2016 Feb; 68(1):185-9. doi: 10.1016/j.pharep.2015.08.008. [PMID: 26721371]
  • Yasir Hasan Siddique, Wasi Khan, Ambreen Fatima, Smita Jyoti, Saba Khanam, Falaq Naz, Rahul, Fahad Ali, Braj Raj Singh, Alim Hussain Naqvi. Effect of bromocriptine alginate nanocomposite (BANC) on a transgenic Drosophila model of Parkinson's disease. Disease models & mechanisms. 2016 Jan; 9(1):63-8. doi: 10.1242/dmm.022145. [PMID: 26542705]
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