Ganhuangenin (BioDeep_00000269697)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2- (4,6-Dihydroxy-2-methoxyphenyl) -5,7-dihydroxy-8-methoxy-4H-1-benzopyran-4-one

化学式: C17H14O8 (346.0689)
中文名称: 粘毛黄芩素III, 粘毛黄芩素 III
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=C(OC)C2OC(C3C(O)=CC=C(O)C=3OC)=CC(=O)C=2C(O)=C1
InChI: InChI=1S/C17H14O8/c1-23-15-8(19)4-3-7(18)14(15)12-6-10(21)13-9(20)5-11(22)16(24-2)17(13)25-12/h3-6,18-20,22H,1-2H3

描述信息

Viscidulin III is a compound isolated from the roots of Scutellaria planipes (L.)[1]. Viscidulin III can inhibit the proliferation of HL-60 (IC50= 17.4μM). Viscidulin III is a potential natural tumor inhibitor[2].
Viscidulin III is a compound isolated from the roots of Scutellaria planipes (L.)[1]. Viscidulin III can inhibit the proliferation of HL-60 (IC50= 17.4μM). Viscidulin III is a potential natural tumor inhibitor[2].

同义名列表

4 个代谢物同义名

Ganhuangenin; 2- (4,6-Dihydroxy-2-methoxyphenyl) -5,7-dihydroxy-8-methoxy-4H-1-benzopyran-4-one; 5,7,3,6-Tetrahydroxy-8,2-dimethoxyflavone; Viscidulin III



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Xuewei Ye, Siran Yu, Ying Liang, Haocai Huang, Xiao-Yuan Lian, Zhizhen Zhang. Bioactive triterpenoid saponins and phenolic compounds against glioma cells. Bioorganic & medicinal chemistry letters. 2014 Nov; 24(22):5157-63. doi: 10.1016/j.bmcl.2014.09.087. [PMID: 25442304]
  • Rüdiger Hardeland, S R Pandi-Perumal. Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. Nutrition & metabolism. 2005 Sep; 2(?):22. doi: 10.1186/1743-7075-2-22. [PMID: 16153306]
  • Ya-lun Su, Yu Huang, Zhen-yu Chen. [Isolation and elucidation of antioxidant constituents from acetone extract in root of Scutellaria rehderiana]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2004 Sep; 29(9):863-4. doi: ". [PMID: 15575204]
  • Beong Ou Lim, Ryo Won Choue, Hyeon Yong Lee, Nak Sul Seong, Jong Dai Kim. Effect of the flavonoid components obtained from Scutellaria radix on the histamine, immunoglobulin E and lipid peroxidation of spleen lymphocytes of Sprague-Dawley rats. Bioscience, biotechnology, and biochemistry. 2003 May; 67(5):1126-9. doi: 10.1271/bbb.67.1126. [PMID: 12834292]
  • Beong Ou Lim. Effect of ganhuangenin obtained from Scutellaria radix on the chemical mediator production of peritoneal exudate cells and immunoglobulin E level of mesenteric lymph node lymphocytes in Sprague-Dawley rats. Phytotherapy research : PTR. 2002 Mar; 16(2):166-70. doi: 10.1002/ptr.1034. [PMID: 11933121]
  • Shuang-Cheng Ma, Jiang Du, Paul Pui-Hay But, Xue-Long Deng, Yong-Wen Zhang, Vincent Eng-Choon Ooi, Hong-Xi Xu, Spencer Hon-Sun Lee, Song Fong Lee. Antiviral Chinese medicinal herbs against respiratory syncytial virus. Journal of ethnopharmacology. 2002 Feb; 79(2):205-11. doi: 10.1016/s0378-8741(01)00389-0. [PMID: 11801383]
  • B O Lim, B P Yu, S C Kim, D K Park. The antioxidative effect of ganhuangenin against lipid peroxidation. Phytotherapy research : PTR. 1999 Sep; 13(6):479-83. doi: 10.1002/(sici)1099-1573(199909)13:6<479::aid-ptr484>3.0.co;2-m. [PMID: 10479757]
  • Y Kimura, H Okuda, Z Taira, N Shoji, T Takemoto, S Arichi. Studies on Scutellariae radix. IX. New component inhibiting lipid peroxidation in rat liver. Planta medica. 1984 Aug; 50(4):290-5. doi: 10.1055/s-2007-969712. [PMID: 6548821]
  • M Wiener, K A Pittman, V Stein. Mirex kinetics in the rhesus monkey. I. Disposition and excretion. Drug metabolism and disposition: the biological fate of chemicals. 1976 May; 4(3):281-7. doi: NULL. [PMID: 6234]