6-Hydroxyrubiadin (BioDeep_00000268002)

   

PANOMIX_OTCML-2023 PANOMIX_OTCML-2025


代谢物信息卡片


1,3,6-Trihydroxy-2-methyl-9,10-anthracenedione; 1,3,6-Trihydroxy-2-methylanthraquinone; 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone; 2-Methyl-1,3,6-trihydroxyanthraquinone

  化学式: C15H10O5 (270.0528)
中文名称: 6-羟基茜草素, 1,3,6-三羟基-2-甲基蒽醌
  谱图信息: 最多检出来源 Arabidopsis thaliana(otcml) 75%

分子结构信息

SMILES: c12c(C(=O)c3c(C1=O)c(c(c(c3)O)C)O)cc(cc2)O
InChI: InChI=1S/C15H10O5/c1-6-11(17)5-10-12(13(6)18)15(20)8-3-2-7(16)4-9(8)14(10)19/h2-5,16-18H,1H3


描述信息

1,3,6-trihydroxy-2-methyl-9,10-anthraquinone is a trihydroxyanthraquinone that is 9,10-anthraquinone substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 2. It has been isolated from the roots of Rubia yunnanensis. It has a role as a plant metabolite.
1,3,6-Trihydroxy-2-methylanthracene-9,10-dione is a natural product found in Rubia argyi, Rubia yunnanensis, and other organisms with data available.

同义名列表

9 个代谢物同义名

1,3,6-Trihydroxy-2-methyl-9,10-anthracenedione; 1,3,6-Trihydroxy-2-methylanthraquinone; 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone; 2-Methyl-1,3,6-trihydroxyanthraquinone; 9,10-anthracenedione, 1,3,6-trihydroxy-2-methyl-; 1,3,6-Trihydroxy-2-methylanthracene-9,10-dione; 1,3,6-trihydroxy-2-methyl-9,10-anthraquinone; 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone; 1,3,6-trihydroxy-2-methylanthraquinone; 2-methyl-1,3,6-trihydroxyanthraquinone; 6-Hydroxyrubiadin; 1,3,6-trihydroxy-2-methyl-anthracene-9,10-dione



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome()

BioCyc()

PlantCyc()

代谢反应

个相关的代谢反应过程信息。

Reactome()

BioCyc()

WikiPathways()

Plant Reactome()

INOH()

PlantCyc()

COVID-19 Disease Map()

PathBank()

PharmGKB()

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Md Badrul Alam, Vivek K Bajpai, Jeong-Sic Ra, Ji-Young Lim, Hongyan An, Shruti Shukla, Khong Trong Quan, Imran Khan, Yun Suk Huh, Young-Kyu Han, MinKyun Na, Sang-Han Lee. Anthraquinone-type inhibitor of α-glucosidase enhances glucose uptake by activating an insulin-like signaling pathway in C2C12 myotubes. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Jul; 129(?):337-343. doi: 10.1016/j.fct.2019.05.005. [PMID: 31071387]
  • Feng Zhao, Sujuan Wang, Xiuli Wu, Yang Yu, Zhenggang Yue, Bo Liu, Sheng Lin, Chenggen Zhu, Yongchun Yang, Jiangong Shi. [Anthraquinones from the roots of Knoxia valerianoides]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Nov; 36(21):2980-6. doi: . [PMID: 22308688]
  • Jun-Ting Fan, Bin Kuang, Guang-Zhi Zeng, Si-Meng Zhao, Chang-Jiu Ji, Yu-Mei Zhang, Ning-Hua Tan. Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis. Journal of natural products. 2011 Oct; 74(10):2069-80. doi: 10.1021/np2002918. [PMID: 21973054]
  • Mi Kyeong Moon, Young-Min Han, Yu-Jin Lee, Lan Hee Lee, Jae Heon Yang, Byoung-Mog Kwon, Dae Keun Kim. Inhibitory activities of anthraquinones from Rubia akane on phosphatase regenerating liver-3. Archives of pharmacal research. 2010 Nov; 33(11):1747-51. doi: 10.1007/s12272-010-1106-4. [PMID: 21116777]
  • Ye Deng, Young-Won Chin, Heebyung Chai, William J Keller, A Douglas Kinghorn. Anthraquinones with quinone reductase-inducing activity and benzophenones from Morinda citrifolia (noni) roots. Journal of natural products. 2007 Dec; 70(12):2049-52. doi: 10.1021/np070501z. [PMID: 18076142]
  • Jing Tao, Toshio Morikawa, Shin Ando, Hisashi Matsuda, Masayuki Yoshikawa. Bioactive constituents from Chinese natural medicines. XI. inhibitors on NO production and degranulation in RBL-2H3 from Rubia yunnanensis: structures of rubianosides II, III, and IV, rubianol-g, and rubianthraquinone. Chemical & pharmaceutical bulletin. 2003 Jun; 51(6):654-62. doi: 10.1248/cpb.51.654. [PMID: 12808242]
  • Toshio Morikawa, Jing Tao, Shin Ando, Hisashi Matsuda, Masayuki Yoshikawa. Absolute stereostructures of new arborinane-type triterpenoids and inhibitors of nitric oxide production from Rubia yunnanensis. Journal of natural products. 2003 May; 66(5):638-45. doi: 10.1021/np0205710. [PMID: 12762798]