Ternatin (BioDeep_00000266261)
PANOMIX_OTCML-2023
代谢物信息卡片
5-Hydroxy-2- (4-hydroxy-3-methoxyphenyl) -3,7,8-trimethoxy-4H-1-benzopyran-4-one
化学式: C19H18O8 (374.1001628)
中文名称: 特拉廷
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c(c1OC)(OC)cc(c(C2=O)c(OC(c(c3)cc(OC)c(O)c3)=C2OC)1)O
InChI: InChI=1S/C19H18O8/c1-23-12-7-9(5-6-10(12)20)16-19(26-4)15(22)14-11(21)8-13(24-2)17(25-3)18(14)27-16/h5-8,20-21H,1-4H3
描述信息
同义名列表
6 个代谢物同义名
4,5-Dihydroxy-3,3,7,8-tetramethoxyflavone; Ternatin; 5,4-Dihydroxy-3,7,8,3-tetramethoxyflavone; Gossypetin 3,7,8,3-tetramethyl ether; 5-Hydroxy-2- (4-hydroxy-3-methoxyphenyl) -3,7,8-trimethoxy-4H-1-benzopyran-4-one; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxy-4H-1-benzopyran-4-one
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:193934
- PubChem: 5459184
- Metlin: METLIN51659
- ChEMBL: CHEMBL73991
- LipidMAPS: LMPK12113247
- KNApSAcK: C00004737
- CAS: 571-71-1
- Flavonoid: FL5FFCNS0017
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kaline Rodrigues Carvalho, Guilherme Julião Zocolo, Rita de Cássia Alves Pereira, Fátima Itana Chaves Custódio Martins, Paulo Riceli Vasconcelos Ribeiro, Edy Sousa de Brito, Edilberto Rocha Silveira, Kirley Marques Canuto. Development of a UPLC-ESI-MS method for simultaneous determination of flavonoids and diterpenes in Egletes viscosa (L.) Less herbal products.
Journal of pharmaceutical and biomedical analysis.
2019 Mar; 166(?):155-163. doi:
10.1016/j.jpba.2019.01.008. [PMID: 30654203] - Sony George, Ramaswamy Venkataraman, Sabulal Baby. Melicodenine I, a new quinolinone alkaloid from Melicope denhamii leaves.
Natural product research.
2017 Apr; 31(8):890-895. doi:
10.1080/14786419.2016.1253075. [PMID: 27817202] - Vimal Nair, Woo Young Bang, Elisa Schreckinger, Nuri Andarwulan, Luis Cisneros-Zevallos. Protective Role of Ternatin Anthocyanins and Quercetin Glycosides from Butterfly Pea (Clitoria ternatea Leguminosae) Blue Flower Petals against Lipopolysaccharide (LPS)-Induced Inflammation in Macrophage Cells.
Journal of agricultural and food chemistry.
2015 Jul; 63(28):6355-65. doi:
10.1021/acs.jafc.5b00928. [PMID: 26120869] - José Ulisses de Souza Melo, Radamés Bezerra Melo, Jefferson Menezes Viana Santos, Manoel Messias Campos Júnior, Sérgio Botelho Guimarães, Paulo Roberto Leitão Vasconcelos. Effects of bioflavonoid ternatin on liver regeneration and oxidative stress in rats.
Acta cirurgica brasileira.
2013 Jun; 28(6):435-40. doi:
10.1590/s0102-86502013000600006. [PMID: 23743681] - J M J Favela-Hernández, A García, E Garza-González, V M Rivas-Galindo, M R Camacho-Corona. Antibacterial and antimycobacterial lignans and flavonoids from Larrea tridentata.
Phytotherapy research : PTR.
2012 Dec; 26(12):1957-60. doi:
10.1002/ptr.4660. [PMID: 22422605] - Guan-Jhong Huang, Jeng-Shyan Deng, Chuan-Sung Chiu, Jung-Chun Liao, Wen-Tsong Hsieh, Ming-Jyh Sheu, Chieh-Hsi Wu. Hispolon Protects against Acute Liver Damage in the Rat by Inhibiting Lipid Peroxidation, Proinflammatory Cytokine, and Oxidative Stress and Downregulating the Expressions of iNOS, COX-2, and MMP-9.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):480714. doi:
10.1155/2012/480714. [PMID: 22013489] - Matsutake Higa, Megumi Imamura, Kanae Shimoji, Kazuhito Ogihara, Toshimasa Suzuka. Isolation of six new flavonoids from Melicope triphylla.
Chemical & pharmaceutical bulletin.
2012; 60(9):1112-7. doi:
10.1248/cpb.c12-00213. [PMID: 22976318] - Clarissa Fernanda de Queiroz Siqueira, Daniela Lyra Vasconcelos Cabral, Tadeu José da Silva Peixoto Sobrinho, Elba Lúcia Cavalcanti de Amorim, Joabe Gomes de Melo, Thiago Antônio de Sousa Araújo, Ulysses Paulino de Albuquerque. Levels of tannins and flavonoids in medicinal plants: evaluating bioprospecting strategies.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):434782. doi:
10.1155/2012/434782. [PMID: 21969842] - Sergio Botelho Guimarães, Jefferson Menezes Viana Santos, Alan Arruda Aragão, Osamu Sandes Kimura, Edilberto R Silveira, Paulo Roberto Leitão de Vasconcelos. Ternatin pretreatment attenuates testicular injury induced by torsion/detorsion in Wistar rats.
Acta cirurgica brasileira.
2011 Aug; 26(4):325-8. doi:
10.1590/s0102-86502011000400014. [PMID: 21808848] - Tannaz Birdi, Poonam Daswani, S Brijesh, Pundarikakshudu Tetali, Arvind Natu, Noshir Antia. Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea.
BMC complementary and alternative medicine.
2010 Jun; 10(?):33. doi:
10.1186/1472-6882-10-33. [PMID: 20584265] - Yoshikazu Tanaka, Filippa Brugliera, Steve Chandler. Recent progress of flower colour modification by biotechnology.
International journal of molecular sciences.
2009 Dec; 10(12):5350-5369. doi:
10.3390/ijms10125350. [PMID: 20054474] - S Brijesh, Poonam Daswani, Pundarikakshudu Tetali, Noshir Antia, Tannaz Birdi. Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: validating its traditional usage.
BMC complementary and alternative medicine.
2009 Nov; 9(?):47. doi:
10.1186/1472-6882-9-47. [PMID: 19930633] - Masahiko Ito, Junko Ito, Hidefumi Kitazawa, Ken Shimamura, Takehiro Fukami, Shigeru Tokita, Kenichiro Shimokawa, Kaoru Yamada, Akio Kanatani, Daisuke Uemura. (-)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells.
Peptides.
2009 Jun; 30(6):1074-81. doi:
10.1016/j.peptides.2009.02.008. [PMID: 19463739] - Kenichiro Shimokawa, Ryoka Miwa, Kaoru Yamada, Daisuke Uemura. Importance of the backbone conformation of (-)-ternatin in its fat-accumulation inhibitory activity against 3T3-L1 adipocytes.
Organic & biomolecular chemistry.
2009 Feb; 7(4):777-84. doi:
10.1039/b818903j. [PMID: 19194593] - Eckhard Wollenweber, Ralf Fischer, Marion Dörr, Kathryn Irvine, Cliff Pereira, Jan F Stevens. Chemodiversity of exudate flavonoids in Cassinia and Ozothamnus (Asteraceae, Gnaphalieae).
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2008 Sep; 63(9-10):731-9. doi:
10.1515/znc-2008-9-1019. [PMID: 19040114] - Milena Morais Vieira, Francisco Yuri B Macêdo, José Nelson Belarmino Filho, Ana Carolina L V Costa, Adriano N Cunha, Edilberto R Silveira, Gerly Anne C Brito, Ronaldo A Ribeiro. Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats.
Phytotherapy research : PTR.
2004 Feb; 18(2):135-41. doi:
10.1002/ptr.1379. [PMID: 15022166] - V S N Rao, L A F Paiva, M F Souza, A R Campos, R A Ribeiro, G A C Brito, M J Teixeira, E R Silveira. Ternatin, an anti-inflammatory flavonoid, inhibits thioglycolate-elicited rat peritoneal neutrophil accumulation and LPS-activated nitric oxide production in murine macrophages.
Planta medica.
2003 Sep; 69(9):851-3. doi:
10.1055/s-2003-43213. [PMID: 14598213] - Sahar R Gedara, Osama B Abdel-Halim, Saleh H el-Sharkawy, Osama M Salama, Thomas W Shier, Ahmed F Halim. New erythroxane-type diterpenoids from Fagonia boveana (Hadidi) Hadidi & Graf.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2003 Jan; 58(1-2):23-32. doi:
10.1515/znc-2003-1-204. [PMID: 12622221] - M F Souza, A R Tomé, V S Rao. Inhibition by the bioflavonoid ternatin of aflatoxin B1-induced lipid peroxidation in rat liver.
The Journal of pharmacy and pharmacology.
1999 Feb; 51(2):125-9. doi:
10.1211/0022357991772222. [PMID: 10217309] - V S Rao, F A Santos, T T Sobreira, M F Souza, C L Melo, E R Silveira. Investigations on the gastroprotective and antidiarrhoeal properties of ternatin, a tetramethoxyflavone from Egletes viscosa.
Planta medica.
1997 Apr; 63(2):146-9. doi:
10.1055/s-2006-957632. [PMID: 9140229] - V S Rao, E G Figueiredo, C L Melo, G S Viana, D B Menezes, M S Matos, E R Silveira. Protective effect of ternatin, a flavonoid isolated from Egletes viscosa less., in experimental liver injury.
Pharmacology.
1994 Jun; 48(6):392-7. doi:
10.1159/000139206. [PMID: 7914024]