Adenanthin (BioDeep_00000263556)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(1S,3S,4aR,6R,6aR,9S,11S,11aS,11bS)-3-hydroxy-4,4,11b-trimethyl-8-methylene-5,7-dioxotetradecahydro-6a,9-methanocyclohepta[a]naphthalene-1,6,11-triyl triacetate

化学式: C26H34O9 (490.2202714)
中文名称: 腺华素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C=C1C(=O)C23CC(=O)C4C(C)(C)C(O)CC(OC(C)=O)C4(C)C2C(OC(C)=O)CC1C3OC(C)=O
InChI: InChI=1S/C26H34O9/c1-11-15-8-16(33-12(2)27)20-25(7)18(34-13(3)28)9-17(30)24(5,6)21(25)19(31)23(35-14(4)29)26(20,10-15)22(11)32/h15-18,20-21,23,30H,1,8-10H2,2-7H3/t15-,16+,17+,18+,20+,21-,23+,25+,26+/m1/s1

描述信息

Adenanthin is a natural product found in Isodon tenuifolius, Isodon adenanthus, and other organisms with data available.

同义名列表

7 个代谢物同义名

(1S,3S,4aR,6R,6aR,9S,11S,11aS,11bS)-3-hydroxy-4,4,11b-trimethyl-8-methylene-5,7-dioxotetradecahydro-6a,9-methanocyclohepta[a]naphthalene-1,6,11-triyl triacetate; [(1R,2R,4R,6S,8S,9S,10S,11S,13S)-2,8-diacetyloxy-6-hydroxy-5,5,9-trimethyl-14-methylidene-3,15-dioxo-11-tetracyclo[11.2.1.01,10.04,9]hexadecanyl] acetate; (1,3,7,11)-1,7,11-Tris(acetyloxy)-3-hydroxykaur-16-ene-6,15-dione; Adenanthin-A; Adenanthin A; AdenanthinA; Adenanthin



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Deena Nath Gupta, Vikram Dalal, Brajesh Kumar Savita, Md Shahid Alam, Anamika Singh, Mrugendra Gubyad, Dilip Kumar Ghosh, Pravindra Kumar, Ashwani Kumar Sharma. Biochemical characterization and structure-based in silico screening of potent inhibitor molecules against the 1 cys peroxiredoxin of bacterioferritin comigratory protein family from Candidatus Liberibacter asiaticus. Journal of biomolecular structure & dynamics. 2023 Jul; 41(12):5776-5788. doi: 10.1080/07391102.2022.2096118. [PMID: 35815556]
  • Jing Hu, Xingren Li, Weifeng Tian, Yanting Lu, Yuhui Xu, Fang Wang, Wanying Qin, Xiuli Ma, Pema-Tenzin Puno, Wenyong Xiong. Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS. Molecules (Basel, Switzerland). 2019 Jan; 24(1):. doi: 10.3390/molecules24010158. [PMID: 30609810]
  • Malgorzata Bajor, Agata O Zych, Agnieszka Graczyk-Jarzynka, Angelika Muchowicz, Malgorzata Firczuk, Lech Trzeciak, Pawel Gaj, Antoni Domagala, Marta Siernicka, Agnieszka Zagozdzon, Pawel Siedlecki, Monika Kniotek, Patrick C O'Leary, Jakub Golab, Radoslaw Zagozdzon. Targeting peroxiredoxin 1 impairs growth of breast cancer cells and potently sensitises these cells to prooxidant agents. British journal of cancer. 2018 10; 119(7):873-884. doi: 10.1038/s41416-018-0263-y. [PMID: 30287919]
  • Wei Wei, Chuanxu Liu, Dongjun Qin, Lili Song, Li Xia, Hu Lei, Yun Yu, Weiwei Wang, Jianxin Pu, Handong Sun, Yingli Wu, Hanzhang Xu, Siguo Hao. Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells. Molecular medicine reports. 2016 Mar; 13(3):2201-7. doi: 10.3892/mmr.2016.4787. [PMID: 26783013]
  • Ying Xu, JinBao Liu, YingLi Wu, QingLong Guo, HanDong Sun, GuoQiang Chen. Natural products against hematological malignancies and identification of their targets. Science China. Life sciences. 2015 Dec; 58(12):1191-201. doi: 10.1007/s11427-015-4922-4. [PMID: 26566803]
  • J-K Hou, Y Huang, W He, Z-W Yan, L Fan, M-H Liu, W-L Xiao, H-D Sun, G-Q Chen. Adenanthin targets peroxiredoxin I/II to kill hepatocellular carcinoma cells. Cell death & disease. 2014 Sep; 5(?):e1400. doi: 10.1038/cddis.2014.345. [PMID: 25188510]
  • Hai-Yan Wu, Rui Zhan, Wei-Guang Wang, Hua-Yi Jiang, Xue Du, Xiao-Nian Li, Yan Li, Jian-Xin Pu, Han-Dong Sun. Cytotoxic ent-kaurane diterpenoids from Isodon wikstroemioides. Journal of natural products. 2014 Apr; 77(4):931-41. doi: 10.1021/np4010135. [PMID: 24697496]
  • Li-Mei Li, Guo-You Li, Li-Sheng Ding, Li-Bin Yang, Yong Zhao, Jian-Xin Pu, Wei-Lie Xiao, Quan-Bin Han, Han-Dong Sun. ent-Kaurane Diterpenoids from Isodon nervosus. Journal of natural products. 2008 Apr; 71(4):684-8. doi: 10.1021/np800027a. [PMID: 18345641]