Skyrin (BioDeep_00000255869)

natural product

代谢物信息卡片

2,2,4,4,5,5-hexahydroxy-7,7-dimethyl-[1S,1-bianthracene]-9,9,10,10-tetrone

化学式: C30H18O10 (538.09)
中文名称: 穗花衫双黄酮
谱图信息: 最多检出来源 Viridiplantae(plant) 100%

分子结构信息

SMILES: C12C(O)=CC(O)=C(C3=C(C=C(O)C4C(=O)C5=C(C=C(C)C=C5O)C(=O)C=43)O)C=1C(=O)C1=C(C(O)=CC(C)=C1)C2=O
InChI: InChI=1S/C30H18O10/c1-9-3-11-19(13(31)5-9)29(39)23-17(35)7-15(33)21(25(23)27(11)37)22-16(34)8-18(36)24-26(22)28(38)12-4-10(2)6-14(32)20(12)30(24)40/h3-8,31-36H,1-2H3

描述信息

同义名列表

4 个代谢物同义名

Skyrin; 2,2,4,4,5,5-hexahydroxy-7,7-dimethyl-[1S,1-bianthracene]-9,9,10,10-tetrone; Rhodophyscin; Endothianin

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:144311
PubChem: 73071
ChEMBL: CHEMBL472851
LipidMAPS: LMPK13040019
KNApSAcK: C00046410
CAS: 131233-49-3
CAS: 35144-94-6
CAS: 602-06-2
MoNA: CCMSLIB00005720075
MoNA: CCMSLIB00005719075
MoNA: CCMSLIB00005719739
MoNA: CCMSLIB00004751385
MoNA: CCMSLIB00004751469
PMhub: MS000208244
LOTUS: LTS0063568

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

52 个相关的物种来源信息

155619 - Agaricomycetes: LTS0063568
4890 - Ascomycota: LTS0063568
1131492 - Aspergillaceae: LTS0063568
5204 - Basidiomycota: LTS0063568
305399 - Chrysoporthe: 10.1038/JA.2015.36
305399 - Chrysoporthe: LTS0063568
34450 - Cortinariaceae: LTS0063568
34451 - Cortinarius: LTS0063568
702292 - Cortinarius icterinoides: 10.1016/S0031-9422(00)89591-6
702292 - Cortinarius icterinoides: 10.1071/CH9950001
702292 - Cortinarius icterinoides: LTS0063568
399129 - Cryphonectriaceae: LTS0063568
47341 - Dermocybe: LTS0063568
2759 - Eukaryota: LTS0063568
147545 - Eurotiomycetes: LTS0063568
4751 - Fungi: LTS0063568
5129 - Hypocreaceae: LTS0063568
5130 - Hypomyces: LTS0063568
557406 - Hypomyces lactifluorum: 10.1016/S0031-9422(00)86529-2
557406 - Hypomyces lactifluorum: LTS0063568
39934 - Lecanora: LTS0063568
1217786 - Lecanora gangaleoides: 10.1039/P19860001491
1217786 - Lecanora gangaleoides: LTS0063568
39933 - Lecanoraceae: LTS0063568
147547 - Lecanoromycetes: LTS0063568
3398 - Magnoliopsida: LTS0063568
474995 - Ophiocordyceps: LTS0063568
72228 - Ophiocordyceps sinensis: 10.1016/J.FOODCHEM.2013.09.001
72228 - Ophiocordyceps sinensis: LTS0063568
474942 - Ophiocordycipitaceae: LTS0063568
5073 - Penicillium: LTS0063568
69768 - Penicillium citreonigrum: 10.1016/0040-4039(95)01602-3
69768 - Penicillium citreonigrum: LTS0063568
64494 - Penicillium citreoviride: LTS0063568
1343377 - Penicillium citreoviride: 10.1016/0040-4039(95)01602-3
3608 - Rhamnaceae: LTS0063568
147550 - Sordariomycetes: LTS0063568
35493 - Streptophyta: LTS0063568
5094 - Talaromyces: LTS0063568
1131644 - Talaromyces brunneus: 10.1248/CPB.11.402
1131644 - Talaromyces brunneus: LTS0063568
28573 - Talaromyces islandicus: 10.1039/J39680001941
28573 - Talaromyces islandicus: 10.1042/BJ0560056
28573 - Talaromyces islandicus: LTS0063568
121627 - Talaromyces rugulosus: 10.1007/BF02876598
121627 - Talaromyces rugulosus: LTS0063568
58023 - Tracheophyta: LTS0063568
28568 - Trichocomaceae: LTS0063568
106719 - Ventilago: LTS0063568
108868 - Ventilago leiocarpa: 10.1021/NP000569D
108868 - Ventilago leiocarpa: LTS0063568
33090 - Viridiplantae: LTS0063568

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Bharadwaj Revuru, Miroslava Bálintová, Jana Henzelyová, Eva Čellárová, Souvik Kusari. MALDI-HRMS Imaging Maps the Localization of Skyrin, the Precursor of Hypericin, and Pathway Intermediates in Leaves of Hypericum Species. Molecules (Basel, Switzerland). 2020 Aug; 25(17):. doi: 10.3390/molecules25173964. [PMID: 32878122]
Katarína Kimáková, Andrea Kimáková, Jakub Idkowiak, Maciej Stobiecki, Paweł Rodziewicz, Łukasz Marczak, Eva Čellárová. Phenotyping the genus Hypericum by secondary metabolite profiling: emodin vs. skyrin, two possible key intermediates in hypericin biosynthesis. Analytical and bioanalytical chemistry. 2018 Nov; 410(29):7689-7699. doi: 10.1007/s00216-018-1384-0. [PMID: 30291388]
Linda Jahn, Thomas Schafhauser, Daniel Wibberg, Christian Rückert, Anika Winkler, Andreas Kulik, Tilmann Weber, Liane Flor, Karl-Heinz van Pée, Jörn Kalinowski, Jutta Ludwig-Müller, Wolfgang Wohlleben. Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris: The anti-cancer bisanthraquinone skyrin. Journal of biotechnology. 2017 Sep; 257(?):233-239. doi: 10.1016/j.jbiotec.2017.06.410. [PMID: 28647529]
Jie Ma, Jianbo Yang, Tengfei Ji, Aiguo Wang, Yalun Su. [Chemical constituents from Hypericum perforatum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Aug; 37(16):2408-12. doi: 10.4268/cjcmm20121613. [PMID: 23234139]
L C Lin, C J Chou, Y C Kuo. Cytotoxic principles from Ventilago leiocarpa. Journal of natural products. 2001 May; 64(5):674-6. doi: 10.1021/np000569d. [PMID: 11374975]