moscatilin (BioDeep_00000247116)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C17H20O5 (304.13106700000003)
中文名称: 石斛酚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1c(c(cc(c1)CCc1cc(c(c(c1)OC)O)OC)OC)O
InChI: InChI=1S/C17H20O5/c1-20-14-8-11(6-7-13(14)18)4-5-12-9-15(21-2)17(19)16(10-12)22-3/h6-10,18-19H,4-5H2,1-3H3
描述信息
Dendrophenol is a natural product found in Cymbidium aloifolium, Dendrobium fimbriatum, and other organisms with data available.
同义名列表
9 个代谢物同义名
Phenol, 4-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,6-dimethoxy-; Phenol, 4-(2-(4-hydroxy-3-methoxyphenyl)ethyl)-2,6-dimethoxy-; 4-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,6-dimethoxyphenol; Dibenzyl, 4,4-dihydroxy-3,3,5-trimethoxy; 4,4-dihydroxy-3,3,5-trimethoxybibenzyl; YTRAYUIKLRABOQ-UHFFFAOYSA-N; Dendrophenol; moscatilin; Aloifol II
数据库引用编号
8 个数据库交叉引用编号
- PubChem: 176096
- MeSH: dendrophenol
- ChemIDplus: 0108853141
- KNApSAcK: C00015530
- CAS: 108853-14-1
- medchemexpress: HY-N6031
- LOTUS: LTS0214903
- wikidata: Q72484885
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Chen-Lin Yu, Meng-Shih Weng, Wei-Cheng Chen, Kai-Ting Chien, Chih-Wen Chi, Ching-Hu Chung, Chia-Wen Huang, Po-Chuan Wang, Chien-Chih Chen, An-Chi Tsai, Shih-Chia Liu, Shih-Wei Wang. Moscatilin Inhibits Metastatic Behavior of Human Hepatocellular Carcinoma Cells: A Crucial Role of uPA Suppression via Akt/NF-κB-Dependent Pathway.
International journal of molecular sciences.
2021 Mar; 22(6):. doi:
10.3390/ijms22062930
. [PMID: 33805784] - Li He, Qian Su, Lan Bai, Meifeng Li, Juanru Liu, Xiaomei Liu, Cunyan Zhang, Zhongliang Jiang, Jun He, Jianyou Shi, Shan Huang, Li Guo. Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species.
European journal of medicinal chemistry.
2020 Oct; 204(?):112530. doi:
10.1016/j.ejmech.2020.112530
. [PMID: 32711292] - Mei Chou Lai, Wayne Young Liu, Shorong-Shii Liou, I-Min Liu. A Bibenzyl Component Moscatilin Mitigates Glycation-Mediated Damages in an SH-SY5Y Cell Model of Neurodegenerative Diseases through AMPK Activation and RAGE/NF-κB Pathway Suppression.
Molecules (Basel, Switzerland).
2020 Oct; 25(19):. doi:
10.3390/molecules25194574
. [PMID: 33036367] - Pichayatri Khoonrit, Alp Mirdogan, Adeline Dehlinger, Wanwimon Mekboonsonglarp, Kittisak Likhitwitayawuid, Josef Priller, Chotima Böttcher, Boonchoo Sritularak. Immune modulatory effect of a novel 4,5-dihydroxy-3,3´,4´-trimethoxybibenzyl from Dendrobium lindleyi.
PloS one.
2020; 15(9):e0238509. doi:
10.1371/journal.pone.0238509
. [PMID: 32870935] - Wen-Haur Chao, Ming-Yi Lai, Hwai-Tzong Pan, Huei-Wen Shiu, Mi-Mi Chen, Hsiao-Ming Chao. Dendrobium nobile Lindley and its bibenzyl component moscatilin are able to protect retinal cells from ischemia/hypoxia by dowregulating placental growth factor and upregulating Norrie disease protein.
BMC complementary and alternative medicine.
2018 Jun; 18(1):193. doi:
10.1186/s12906-018-2256-z
. [PMID: 29933759] - Feng-Qing Xu, Fang-Cheng Xu, Bo Hou, Wei-Wei Fan, Cheng-Ting Zi, Yan Li, Fa-Wu Dong, Yu-Qing Liu, Jun Sheng, Zhi-Li Zuo, Jiang-Miao Hu. Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook.
Bioorganic & medicinal chemistry letters.
2014 Nov; 24(22):5268-73. doi:
10.1016/j.bmcl.2014.09.052
. [PMID: 25316316] - Chen-Yuan Gong, Bin Lu, Li Yang, Lei Wang, Li-Li Ji. [Bibenzyl from Dendrobium inhibits angiogenesis and its underlying mechanism].
Yao xue xue bao = Acta pharmaceutica Sinica.
2013 Mar; 48(3):337-42. doi:
. [PMID: 23724644]
- An-Chi Tsai, Shiow-Lin Pan, Cho-Hwa Liao, Jih-Hwa Guh, Shih-Wei Wang, Hui-Lung Sun, Yi-Nan Liu, Chien-Chih Chen, Chien-Chang Shen, Ya-Ling Chang, Che-Ming Teng. Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo.
Cancer letters.
2010 Jun; 292(2):163-70. doi:
10.1016/j.canlet.2009.11.020
. [PMID: 20056528] - Ji Sang Hwang, Seon A Lee, Seong Su Hong, Xiang Hua Han, Chul Lee, Shin Jung Kang, Dongho Lee, Youngsoo Kim, Jin Tae Hong, Mi Kyeong Lee, Bang Yeon Hwang. Phenanthrenes from Dendrobium nobile and their inhibition of the LPS-induced production of nitric oxide in macrophage RAW 264.7 cells.
Bioorganic & medicinal chemistry letters.
2010 Jun; 20(12):3785-7. doi:
10.1016/j.bmcl.2010.04.054
. [PMID: 20483604] - Huanjie Yang, Jinbao Liu, Q Ping Dou. Targeting tumor proteasome with traditional Chinese medicine.
Current drug discovery technologies.
2010 Mar; 7(1):46-53. doi:
10.2174/157016310791162785
. [PMID: 20156140] - Xue Zhang, Jie-Kun Xu, Jue Wang, Nai-Li Wang, Hiroshi Kurihara, Sumumu Kitanaka, Xin-Sheng Yao. Bioactive bibenzyl derivatives and fluorenones from Dendrobium nobile.
Journal of natural products.
2007 Jan; 70(1):24-8. doi:
10.1021/np060449r
. [PMID: 17253844] - Yanet Hernández-Romero, Juana-Isela Rojas, Rafael Castillo, Alejandra Rojas, Rachel Mata. Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.
Journal of natural products.
2004 Feb; 67(2):160-7. doi:
10.1021/np030303h
. [PMID: 14987052] - Chi-Kuan Ho, Chieh-Chih Chen. Moscatilin from the orchid Dendrobrium loddigesii is a potential anticancer agent.
Cancer investigation.
2003; 21(5):729-36. doi:
10.1081/cnv-120023771
. [PMID: 14628431] - Hai-lin Qin, Jian-xin Zhang, Zheng-tao Wang, Xiao-sheng Yang, Luo-shan Xu, Xiao-jiang Hao. [Analysis of 1H-NMR fingerprint in stem of Dendrobium loddigesii].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2002 Dec; 27(12):919-23. doi:
"
. [PMID: 12776532] - H Y Chen, M S Shiao, Y L Huang, C C Shen, Y L Lin, Y H Kuo, C C Chen. Antioxidant principles from Ephemerantha lonchophylla.
Journal of natural products.
1999 Sep; 62(9):1225-7. doi:
10.1021/np990025f
. [PMID: 10514302] - M Miyazawa, H Shimamura, S Nakamura, W Sugiura, H Kosaka, H Kameoka. Moscatilin from Dendrobium nobile, a naturally occurring bibenzyl compound with potential antimutagenic activity.
Journal of agricultural and food chemistry.
1999 May; 47(5):2163-7. doi:
10.1021/jf970930a
. [PMID: 10552513] - M F Li, Y Hirata, G J Xu, M Niwa, H M Wu. [Studies on the chemical constituents of Dendrobium loddigesii rolfe].
Yao xue xue bao = Acta pharmaceutica Sinica.
1991; 26(4):307-10. doi:
. [PMID: 1659772]