Ethyl formate (BioDeep_00000024627)

   

human metabolite Endogenous


代谢物信息卡片


Ethyl ester OF formic acid

化学式: C3H6O2 (74.0367776)
中文名称: 甲酸乙酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCOC=O
InChI: InChI=1S/C3H6O2/c1-2-5-3-4/h3H,2H2,1H3

描述信息

Ethyl formate, also known as areginal or ethyl methanoate, belongs to the class of organic compounds known as carboxylic acid esters. These are carboxylic acid derivatives in which the carbon atom from the carbonyl group is attached to an alkyl or an aryl moiety through an oxygen atom (forming an ester group). Ethyl formate is an alcohol, bitter, and cognac tasting compound. Ethyl formate has been detected, but not quantified, in several different foods, such as citrus, pineapples, apples, fruits, and pomes. This could make ethyl formate a potential biomarker for the consumption of these foods. It occurs naturally in the body of ants and in the stingers of bees. Ethyl formate has the characteristic smell of rum and is also partially responsible for the flavor of raspberries. The U.S. National Institute for Occupational Safety and Health (NIOSH) also considers a time-weighted average of 100 ppm over an eight-hour period as the recommended exposure limit. Ethyl formate is an ester formed when ethanol (an alcohol) reacts with formic acid (a carboxylic acid). According to the U.S Occupational Safety and Health Administration (OSHA), ethyl formate can irritate eyes, skin, mucous membranes, and the respiratory system of humans and other animals; it is also a central nervous system depressant. Ethyl formate has been identified in dust clouds in an area of the Milky Way galaxy called Sagittarius B2 and it is among 50 molecular species identified using the 30 metre IRAM radiotelescope. In industry, it is used as a solvent for cellulose nitrate, cellulose acetate, oils, and greases.
Found in various foods, e.g. cooked apple, orange juice, pineapple, other fruits, raw cabbage, coffee, black tea, wheat bread, white clover, sorghum. It is used as a flavouring agent.

同义名列表

19 个代谢物同义名

Ethyl ester OF formic acid; Carboxylic acid oxaethane; Formic acid, ethyl ester; Formic acid ethyl ester; Ethyle (formiic acid d); Carboxylate oxaethane; Ethyl methanoic acid; Formate, ethyl ester; Ethyle (formiate d); Ethyl formic ester; Formiato de etilo; Ethyl formic acid; Ethylformic ester; Ethyl methanoate; Ethylformiaat; ETHYL FORMATE; Aethylformiat; Formic ether; Areginal



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

19 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • James C Kawagoe, Adelaine E Abrams, Austin P Lourie, Spencer S Walse. Ethyl formate dilution in carbon dioxide for fumigation control of the brown marmorated stink bug Halyomorpha halys, Stål (Hemiptera: Pentatomidae). Pest management science. 2022 Jul; 78(7):3090-3097. doi: 10.1002/ps.6935. [PMID: 35437899]
  • Min-Goo Park, Byung-Ho Lee, Jeong-Oh Yang, Bong-Soo Kim, Gwang Hyun Roh, Paul E Kendra, Dong H Cha. Ethyl Formate as a Methyl Bromide Alternative for Fumigation of Citrus: Efficacy, Fruit Quality, and Workplace Safety. Journal of economic entomology. 2021 12; 114(6):2290-2296. doi: 10.1093/jee/toab175. [PMID: 34622933]
  • Min-Goo Park, Chung-Gyoo Park, Jeong-Oh Yang, Gil-Hah Kim, Yonglin Ren, Byung-Ho Lee, Dong H Cha. Ethyl Formate as a Methyl Bromide Alternative for Phytosanitary Disinfestation of Imported Banana in Korea With Logistical Considerations. Journal of economic entomology. 2020 08; 113(4):1711-1717. doi: 10.1093/jee/toaa088. [PMID: 32372093]
  • Kyeongnam Kim, Jeong Oh Yang, Jae-Yoon Sung, Ji-Young Lee, Jeong Sun Park, Heung-Sik Lee, Byung-Ho Lee, Yonglin Ren, Dong-Woo Lee, Sung-Eun Lee. Minimization of energy transduction confers resistance to phosphine in the rice weevil, Sitophilus oryzae. Scientific reports. 2019 10; 9(1):14605. doi: 10.1038/s41598-019-50972-w. [PMID: 31601880]
  • Yejin Kyung, Hyun Kyung Kim, Sung Woo Cho, Bong-Su Kim, Jeong-Oh Yang, Hyun-Na Koo, Gil-Hah Kim. Comparison of the Efficacy and Phytotoxicity of Phosphine and Ethyl Formate for Controlling Pseudococcus longispinus (Hemiptera: Pseudococcidae) and Pseudococcus orchidicola on Imported Foliage Nursery Plants. Journal of economic entomology. 2019 09; 112(5):2149-2156. doi: 10.1093/jee/toz125. [PMID: 31115458]
  • V N Bikoba, F Pupin, W V Biasi, F U Rutaganira, E J Mitcham. Use of Ethyl Formate Fumigation to Control Adult Bean Thrips in Navel Oranges. Journal of economic entomology. 2019 03; 112(2):591-596. doi: 10.1093/jee/toy369. [PMID: 30535105]
  • Jae Seon Lee, Hyun Kyung Kim, Yejin Kyung, Geun-Ho Park, Byung-Ho Lee, Jeong-Oh Yang, Hyun-Na Koo, Gil-Hah Kim. Fumigation Activity of Ethyl Formate and Phosphine Against Tetranychus urticae (Acari: Tetranychidae) on Imported Sweet Pumpkin. Journal of economic entomology. 2018 08; 111(4):1625-1632. doi: 10.1093/jee/toy090. [PMID: 29757437]
  • Marija Nišavić, Amela Hozić, Zdenko Hameršak, Martina Radić, Ana Butorac, Marija Duvnjak, Mario Cindrić. High-Efficiency Microflow and Nanoflow Negative Electrospray Ionization of Peptides Induced by Gas-Phase Proton Transfer Reactions. Analytical chemistry. 2017 05; 89(9):4847-4854. doi: 10.1021/acs.analchem.6b04466. [PMID: 28372357]
  • JeongOh Yang, Youngrong Park, Ik-Hwa Hyun, Gil-Hah Kim, Bong-Su Kim, Byung-Ho Lee, YongLin Ren. A Combination Treatment Using Ethyl Formate and Phosphine to Control Planococcus citri (Hemiptera: Pseudococcidae) on Pineapples. Journal of economic entomology. 2016 12; 109(6):2355-2363. doi: 10.1093/jee/tow222. [PMID: 27986937]
  • Hyun Kyung Kim, Seon-Woo Lee, Ju-Il Kim, Jeong-Oh Yang, Hyun-Na Koo, Gil-Hah Kim. Synergistic Effects of Oxygen on Phosphine and Ethyl Formate for the Control of Phthorimaea operculella (Lepidoptera: Gelechiidae). Journal of economic entomology. 2015 Dec; 108(6):2572-80. doi: 10.1093/jee/tov244. [PMID: 26470389]
  • Manjree Agarwal, Yonglin Ren, James Newman, Stewart Learmonth. Ethyl Formate: A Potential Disinfestation Treatment for Eucalyptus Weevil (Gonipterus platensis) (Coleoptera: Curculionidae) in Apples. Journal of economic entomology. 2015 Dec; 108(6):2566-71. doi: 10.1093/jee/tov242. [PMID: 26470387]
  • Haithem Bessi, Sihem Bellagha, Kaouthar Grissa Lebdi, Veronique Bikoba, Elizabeth J Mitcham. Ethyl Formate Fumigation of Dry and Semidry Date Fruits: Experimental Kinetics, Modeling, and Lethal Effect on Carob Moth. Journal of economic entomology. 2015 Jun; 108(3):993-9. doi: 10.1093/jee/tov032. [PMID: 26470221]
  • Francine Pupin, Veronique Bikoba, William B Biasi, Gabriel M Pedroso, Yuling Ouyang, Elizabeth E Grafton-Cardwell, Elizabeth J Mitcham. Postharvest control of western flower thrips (Thysanoptera: Thripidae) and California red scale (Hemiptera: Diaspididae) with ethyl formate and its impact on citrus fruit quality. Journal of economic entomology. 2013 Dec; 106(6):2341-8. doi: 10.1603/ec13111. [PMID: 24498732]
  • YongLin Ren, Byungho Lee, Benjamin Padovan, Lijun Cai. Ethyl formate plus methyl isothiocyanate--a potential liquid fumigant for stored grains. Pest management science. 2012 Feb; 68(2):194-201. doi: 10.1002/ps.2244. [PMID: 21780282]
  • Alinanuswe S Mwakaboko, Binne Zwanenburg. Strigolactone analogs derived from ketones using a working model for germination stimulants as a blueprint. Plant & cell physiology. 2011 Apr; 52(4):699-715. doi: 10.1093/pcp/pcr031. [PMID: 21421570]
  • James Darby, Tracy Willis, Katherine Damcevski. Modelling the kinetics of ethyl formate sorption by wheat using batch experiments. Pest management science. 2009 Sep; 65(9):982-90. doi: 10.1002/ps.1783. [PMID: 19466692]
  • Sarosh N Fatakia, Stefano Costanzi, Carson C Chow. Computing highly correlated positions using mutual information and graph theory for G protein-coupled receptors. PloS one. 2009; 4(3):e4681. doi: 10.1371/journal.pone.0004681. [PMID: 19262747]
  • Man-Jeong Paik, Jinwoo Lee, Kyoung-Rae Kim. Simultaneous screening analysis of multiple beta-blockers in urine by gas chromatography-mass spectrometry in selected ion monitoring mode. Analytica chimica acta. 2007 Oct; 601(2):230-3. doi: 10.1016/j.aca.2007.08.036. [PMID: 17920396]
  • T Simpson, V Bikoba, C Tipping, E J Mitcham. Ethyl formate as a postharvest fumigant for selected pests of table grapes. Journal of economic entomology. 2007 Aug; 100(4):1084-90. doi: 10.1603/0022-0493(2007)100[1084:efaapf]2.0.co;2. [PMID: 17849855]
  • Sang-Wook Sun, Young-Il Jeong, Sung-Ho Kim. Surfactant-free microspheres of poly(epsilon-caprolactone)/poly (ethylene glycol)/poly(epsilon-caprolactone) triblock copolymers as a protein carrier. Archives of pharmacal research. 2003 Jun; 26(6):504-10. doi: 10.1007/bf02976871. [PMID: 12877563]
  • I Made S Utama, Ron B H Wills, Shimshon Ben-Yehoshua, Clem Kuek. In vitro efficacy of plant volatiles for inhibiting the growth of fruit and vegetable decay microorganisms. Journal of agricultural and food chemistry. 2002 Oct; 50(22):6371-7. doi: 10.1021/jf020484d. [PMID: 12381119]
  • J B Laurens, X Y Mbianda, J H Spies, J B Ubbink, W J H Vermaak. Validated method for quantitation of biomarkers for benzene and its alkylated analogues in urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Jul; 774(2):173-85. doi: 10.1016/s1570-0232(02)00206-4. [PMID: 12076687]
  • Ruey-Shin Juang, Tsye-Shing Lee. Oxidative pyrolysis of organic ion exchange resins in the presence of metal oxide catalysts. Journal of hazardous materials. 2002 Jun; 92(3):301-14. doi: 10.1016/s0304-3894(02)00025-0. [PMID: 12031614]
  • Daune L Crankshaw, Lorelle I Berkeley, Jonathan F Cohen, Frances N Shirota, Herbert T Nagasawa. Double-prodrugs of L-cysteine: differential protection against acetaminophen-induced hepatotoxicity in mice. Journal of biochemical and molecular toxicology. 2002; 16(5):235-44. doi: 10.1002/jbt.10044. [PMID: 12439865]
  • H T Nagasawa, E G DeMaster, D J Goon, S P Kawle, F N Shirota. Carbethoxylating agents as inhibitors of aldehyde dehydrogenase. Journal of medicinal chemistry. 1995 May; 38(11):1872-6. doi: 10.1021/jm00011a006. [PMID: 7783119]