Juncusol (BioDeep_00000241842)

   

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


2,7-dihydroxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthrene

化学式: C18H18O2 (266.1306728)
中文名称: 6-甲基灯心草二酚, 灯心草酚
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 66.67%

分子结构信息

SMILES: C=Cc1c(C)c(O)cc2c1-c1ccc(O)c(C)c1CC2
InChI: InChI=1S/C18H18O2/c1-4-13-10(2)17(20)9-12-5-6-14-11(3)16(19)8-7-15(14)18(12)13/h4,7-9,19-20H,1,5-6H2,2-3H3

描述信息

Juncusol is a natural product found in Juncus effusus, Juncus acutus, and Juncus roemerianus with data available.

同义名列表

12 个代谢物同义名

2,7-dihydroxy-1,6-dimethyl-5-vinyl-9,10-dihydrophenanthrene; 2,7-Phenanthrenediol, 5-ethenyl-9,10-dihydro-1,6-dimethyl-; 5-ETHENYL-9,10-DIHYDRO-1,6-DIMETHYL-2,7-PHENANTHRENEDIOL; 5-ethenyl-1,6-dimethyl-9,10-dihydrophenanthrene-2,7-diol; 1,6-Dimethyl-5-vinyl-9,10-dihydro-phenanthrene-2,7-diol; 1,6-dimethyl-5-vinyl-9,10-dihydrophenanthrene-2,7-diol; 2, 5-ethenyl-9,10-dihydro-1,6-dimethyl-; UNII-6T481HU7OI; NCI60_001834; 6T481HU7OI; Juncusol; juncunol



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • László Bakacsy, Lilla Sípos, Anita Barta, Dóra Stefkó, Andrea Vasas, Ágnes Szepesi. Concentration-dependent effects of effusol and juncusol from Juncus compressus on seedling development of Arabidopsis thaliana. Scientific reports. 2022 08; 12(1):13870. doi: 10.1038/s41598-022-18063-5. [PMID: 35974076]
  • Csaba Bús, Norbert Kúsz, Annamária Kincses, Nikoletta Szemerédi, Gabriella Spengler, László Bakacsy, Dragica Purger, Róbert Berkecz, Judit Hohmann, Attila Hunyadi, Andrea Vasas. Antiproliferative Phenanthrenes from Juncus tenuis: Isolation and Diversity-Oriented Semisynthetic Modification. Molecules (Basel, Switzerland). 2020 Dec; 25(24):. doi: 10.3390/molecules25245983. [PMID: 33348712]
  • Dóra Stefkó, Norbert Kúsz, Anita Barta, Zoltán Kele, László Bakacsy, Ágnes Szepesi, Csilla Fazakas, Imola Wilhelm, István A Krizbai, Judit Hohmann, Andrea Vasas. Gerardiins A-L and Structurally Related Phenanthrenes from the Halophyte Plant Juncus gerardii and Their Cytotoxicity against Triple-Negative Breast Cancer Cells. Journal of natural products. 2020 10; 83(10):3058-3068. doi: 10.1021/acs.jnatprod.0c00631. [PMID: 33054206]
  • Xue Li, Yilin Qiao, Xue Wang, Ruicong Ma, Tianxiang Li, Youcai Zhang, Robert P Borris. Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3. Journal of natural products. 2019 04; 82(4):832-839. doi: 10.1021/acs.jnatprod.8b00888. [PMID: 30892891]
  • Barbara Tóth, Judit Hohmann, Andrea Vasas. Phenanthrenes: A Promising Group of Plant Secondary Metabolites. Journal of natural products. 2018 03; 81(3):661-678. doi: 10.1021/acs.jnatprod.7b00619. [PMID: 29280630]
  • Barbara Tóth, Erika Liktor-Busa, Norbert Kúsz, Ádám Szappanos, Attila Mándi, Tibor Kurtán, Edit Urbán, Judit Hohmann, Fang-Rong Chang, Andrea Vasas. Phenanthrenes from Juncus inflexus with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus. Journal of natural products. 2016 11; 79(11):2814-2823. doi: 10.1021/acs.jnatprod.6b00581. [PMID: 27808510]
  • A A de la Cruz, D H Miles, K D Chapatwala. Toxic effects of juncusol, a marsh plant phenolic extract, on estuarine fish and shrimp. Life sciences. 1982 May; 30(21):1805-10. doi: 10.1016/0024-3205(82)90317-4. [PMID: 7098770]
  • K D Chapatwala, A A de la Cruz, D H Miles. Antimicrobial activity of juncusol, a novel 9-10-dihydrophenanthrene from the marsh plant Juncus roemerianus. Life sciences. 1981 Nov; 29(19):1997-2001. doi: 10.1016/0024-3205(81)90609-3. [PMID: 6796796]
  • D H Miles, J Bhattacharyya, N V Mody, J L Atwood, S Black, P A Hedin. The structure of juncusol. A novel cytotoxic dihydrophenanthrene from the Estuarine marsh plant Juncus roemerianus. Journal of the American Chemical Society. 1977 Jan; 99(2):618-20. doi: 10.1021/ja00444a056. [PMID: 830696]