1-Butanethiol (BioDeep_00000023960)

   

human metabolite Endogenous


代谢物信息卡片


N-Butyl mercaptan, 1,2-(14)C,2-(35) S-labeled CPD

化学式: C4H10S (90.050318)
中文名称: 正丁硫醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCS
InChI: InChI=1S/C4H10S/c1-2-3-4-5/h5H,2-4H2,1H3

描述信息

1-Butanethiol, also known as 1-butyl mercaptan or 1-butylthiol, belongs to the class of organic compounds known as alkylthiols. These are organic compounds containing the thiol functional group linked to an alkyl chain. 1-Butanethiol is a coffee, egg, and garlic tasting compound. 1-Butanethiol has been detected, but not quantified, in milk and milk products and potato. Commercially, this is performed using ultraviolet light. It is sometimes placed in the "stink bombs" and "stink perfumes" for pranksters. Butanethiol is a very noxious and caustic chemical compound, and at sufficiently high concentrations, it produces serious health effects in both humans and animals, especially as a result of prolonged exposure. It may cause effects on the thyroid and the nervous system and could cause lowering of consciousness. The scent of butanethiol is so strong that the human nose can easily detect it in the air at concentrations as low as 10 parts per billion. The substance irritates the eyes, the skin, and the respiratory tract. Butanethiol is a thiol of low molecular weight, and it is highly flammable. Butanethiol is used as an industrial solvent, and as an intermediate for cotton defoliants. The threshold level for 1-butanethiol is reported as 1.4 ppb. Butanethiol is chemically classified among the thiols, which are organic compounds with molecular formulas and structural formulas similar to alcohols, except that sulfur-containing sulfhydryl group (-SH) replaces the oxygen-containing hydroxyl group (-OH) in the molecule. Butanethiol is prepared by the free radical catalyzed addition of hydrogen sulfide to 1-butene. Contact with the skin and mucous membranes causes burns, and contact with the eyes can lead to blurred vision or complete blindness. Inhalation may cause weakness, confusion, cough, dizziness, drowsiness, headache, nausea, vomiting, and shortness of breath.
1-Butanethiol is a flavouring agent. It is found in animal foods such as beef and raw chicken. It is also found in cooked potatoes and in milk and milk products (e.g. Cheshire cheese).

同义名列表

33 个代谢物同义名

N-Butyl mercaptan, 1,2-(14)C,2-(35) S-labeled CPD; N-Butyl mercaptan, 2-(14)C,2-(35)S-labeled CPD; N-Butyl mercaptan, 14C,1-(35)S-labeled CPD; N-Butyl mercaptan, molybdenum (+3) salt; N-Butyl mercaptan, geranium (+2) salt; N-Butyl mercaptan, copper (+1) salt; N-Butyl mercaptan, silver (+2) salt; N-Butyl mercaptan, potassium salt; N-Butyl mercaptan, lead (+2) salt; N-Butyl mercaptan, tin (+2) salt; N-Butyl mercaptan, lithium salt; N-Butyl mercaptan, ag(+1) salt; N-Butyl mercaptan, sodium salt; Normal butyl thioalcohol; N-Butyl thioalcohol; Butyl thioalcohol; n-Butyl mercaptan; Thiobutyl alcohol; 1-Butyl mercaptan; N-Butylmercaptan; 1-Mercaptobutane; Butyl mercaptan; Butane-1-thiol; N-Butanethiol; 1-Butanethiol; N-Butylthiol; 1-Butylthiol; Mercaptan C4; butanethiol; Butylthiol; Bear skunk; FEMA 3478; N-C4H9SH



数据库引用编号

10 个数据库交叉引用编号

分类词条

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代谢反应

0 个相关的代谢反应过程信息。

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2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Priyanka A Oroskar, Cynthia J Jameson, Sohail Murad. Surface-functionalized nanoparticle permeation triggers lipid displacement and water and ion leakage. Langmuir : the ACS journal of surfaces and colloids. 2015 Jan; 31(3):1074-85. doi: 10.1021/la503934c. [PMID: 25549137]
  • Hyeon-Yeong Kim, Sung-Bae Lee, Hae-Won Cho, Min-Gu Kang, Jeong-Sun Yang, In-Sik Shin, Jong-Choon Kim. Evaluation of 13-week inhalation toxicity of sec-butanethiol in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2009 Sep; 47(9):2294-301. doi: 10.1016/j.fct.2009.06.017. [PMID: 19527766]
  • Grigor B Bantchev, James A Kenar, Girma Biresaw, Moon Gyu Han. Free radical addition of butanethiol to vegetable oil double bonds. Journal of agricultural and food chemistry. 2009 Feb; 57(4):1282-90. doi: 10.1021/jf802774g. [PMID: 19166316]
  • Brajendra K Sharma, A Adhvaryu, S Z Erhan. Synthesis of hydroxy thio-ether derivatives of vegetable oil. Journal of agricultural and food chemistry. 2006 Dec; 54(26):9866-72. doi: 10.1021/jf061896f. [PMID: 17177513]
  • Shigeyuki Oguri, Yuko Maeda, Aki Mizusawa. On-column derivatization-capillary electrochromatography with o-phthalaldehyde/alkylthiol for assay of biogenic amines. Journal of chromatography. A. 2004 Jul; 1044(1-2):271-6. doi: 10.1016/j.chroma.2004.04.053. [PMID: 15354448]
  • Richard N Bennett, Fred A Mellon, Nigel P Botting, John Eagles, Eduardo A S Rosa, Gary Williamson. Identification of the major glucosinolate (4-mercaptobutyl glucosinolate) in leaves of Eruca sativa L. (salad rocket). Phytochemistry. 2002 Sep; 61(1):25-30. doi: 10.1016/s0031-9422(02)00203-0. [PMID: 12165298]
  • K M Abdo, P R Timmons, D G Graham, M B Abou-Donia. Heinz body production and hematological changes in the hen after administration of a single oral dose of n-butyl mercaptan and n-butyl disulfide. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1983 Mar; 3(2):69-74. doi: 10.1016/s0272-0590(83)80058-x. [PMID: 6873530]