(R)-3-Hydroxy-Octadecanoic acid (BioDeep_00000023844)

   

human metabolite Endogenous


代谢物信息卡片


(R)-3-Hydroxy-Octadecanoic acid

化学式: C18H36O3 (300.2664)
中文名称: 3-羟基十八烷酸
谱图信息: 最多检出来源 Homo sapiens(endogenous) 9.56%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(CC(=O)O)O
InChI: InChI=1S/C18H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19)16-18(20)21/h17,19H,2-16H2,1H3,(H,20,21)

描述信息

In humans fatty acids are predominantly formed in the liver and adipose tissue, and mammary glands during lactation. (R)-3-Hydroxy-Octadecanoic acid is an intermediate in fatty acid biosynthesis. Specifically, (R)-3-Hydroxy-Octadecanoic acid is converted from 3-Oxo-Octadecanoic acid via 3-oxoacyl- [acyl-carrier-protein] reductase. (EC: 1.1.1.100) [HMDB]
In humans fatty acids are predominantly formed in the liver and adipose tissue, and mammary glands during lactation. (R)-3-Hydroxy-Octadecanoic acid is an intermediate in fatty acid biosynthesis. Specifically, (R)-3-Hydroxy-Octadecanoic acid is converted from 3-Oxo-Octadecanoic acid via 3-oxoacyl- [acyl-carrier-protein] reductase. (EC: 1.1.1.100).

同义名列表

5 个代谢物同义名

(R)-3-Hydroxy-Octadecanoic acid; (3R)-3-hydroxyoctadecanoic acid; (R)-3-Hydroxy-octadecanoate; 3-hydroxyoctadecanoic acid; 3R-Hydroxy-octadecanoate



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Akhilesh Kumar Singh, Nirupama Mallick. Exploitation of inexpensive substrates for production of a novel SCL-LCL-PHA co-polymer by Pseudomonas aeruginosa MTCC 7925. Journal of industrial microbiology & biotechnology. 2009 Mar; 36(3):347-54. doi: 10.1007/s10295-008-0503-x. [PMID: 19052786]
  • Yanfang Su, Lei Chen, Dawei Wang, Xin Chai, Dean Guo. A new labdane diterpenoid arabinoside from Conyza blinii. Natural product research. 2008 Apr; 22(6):521-4. doi: 10.1080/14786410701592232. [PMID: 18415860]
  • Madhurima Dhar, Daniel W Sepkovic, Vandana Hirani, Ronald P Magnusson, Jerome M Lasker. Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11. Journal of lipid research. 2008 Mar; 49(3):612-24. doi: 10.1194/jlr.m700450-jlr200. [PMID: 18065749]
  • Scott A Shaffer, Megan D Harvey, David R Goodlett, Robert K Ernst. Structural heterogeneity and environmentally regulated remodeling of Francisella tularensis subspecies novicida lipid A characterized by tandem mass spectrometry. Journal of the American Society for Mass Spectrometry. 2007 Jun; 18(6):1080-92. doi: 10.1016/j.jasms.2007.03.008. [PMID: 17446084]
  • Xiaoyuan Wang, Anthony A Ribeiro, Ziqiang Guan, Sara C McGrath, Robert J Cotter, Christian R H Raetz. Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida. Biochemistry. 2006 Dec; 45(48):14427-40. doi: 10.1021/bi061767s. [PMID: 17128982]
  • Benjamin Jeyaretnam, John Glushka, V S Kumar Kolli, Russell W Carlson. Characterization of a novel lipid-A from Rhizobium species Sin-1. A unique lipid-A structure that is devoid of phosphate and has a glycosyl backbone consisting of glucosamine and 2-aminogluconic acid. The Journal of biological chemistry. 2002 Nov; 277(44):41802-10. doi: 10.1074/jbc.m112140200. [PMID: 12193590]
  • Y Suda, Y M Kim, T Ogawa, N Yasui, Y Hasegawa, W Kashihara, T Shimoyama, K Aoyama, K Nagata, T Tamura, S Kusumoto. Chemical structure and biological activity of a lipid A component from Helicobacter pylori strain 206. Journal of endotoxin research. 2001; 7(2):95-104. doi: ". [PMID: 11521089]