12-Hydroxystearic acid (BioDeep_00000023656)

   

human metabolite Endogenous


代谢物信息卡片


12-hydroxy-octadecanoic acid

化学式: C18H36O3 (300.2664)
中文名称: 12-羟基硬脂酸, 十二羟基硬脂酸
谱图信息: 最多检出来源 Homo sapiens(feces) 12.85%

分子结构信息

SMILES: CCCCCCC(CCCCCCCCCCC(=O)O)O
InChI: InChI=1S/C18H36O3/c1-2-3-4-11-14-17(19)15-12-9-7-5-6-8-10-13-16-18(20)21/h17,19H,2-16H2,1H3,(H,20,21)

描述信息

12-Hydroxystearic acid, also known as 12-HSA, (CAS# 36377-33-0), can be found in edible vegetable oils such as canola oil and castor oil

同义名列表

15 个代谢物同义名

12-hydroxy-octadecanoic acid; 12-HYDROXYOCTADECANOIC ACID; DL-12-hydroxy stearic acid; 12-DL-Hydroxystearic acid; DL-12-Hydroxystearic acid; 12-Hydroxy-octadecanoate; 12-Hydroxyoctadecanoate; 12-Hydroxy stearic acid; 12-Hydroxystearic acid; DL-12-Hydroxy stearate; DL-12-Hydroxystearate; 12-Hydroxystearate; UNII:933ANU3H2S; 18:0(12-OH); 12-hydroxystearic acid



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Chao Qin, Yaqi Lv, Chaoran Xu, Jingjing Li, Lifang Yin, Wei He. Lipid-bilayer-coated nanogels allow for sustained release and enhanced internalization. International journal of pharmaceutics. 2018 Nov; 551(1-2):8-13. doi: 10.1016/j.ijpharm.2018.09.008. [PMID: 30196141]
  • Kazunori Iwanaga, Mineo Kawai, Makoto Miyazaki, Masawo Kakemi. Application of organogels as oral controlled release formulations of hydrophilic drugs. International journal of pharmaceutics. 2012 Oct; 436(1-2):869-72. doi: 10.1016/j.ijpharm.2012.06.041. [PMID: 22766444]
  • Aswani Dutt Vadlapudi, Ramya Krishna Vadlapatla, Deep Kwatra, Ravinder Earla, Swapan K Samanta, Dhananjay Pal, Ashim K Mitra. Targeted lipid based drug conjugates: a novel strategy for drug delivery. International journal of pharmaceutics. 2012 Sep; 434(1-2):315-24. doi: 10.1016/j.ijpharm.2012.05.033. [PMID: 22692074]
  • Ya Zhang, Weikai Zhang, Marian Löbler, Klaus-Peter Schmitz, Patrick Saulnier, Thomas Perrier, Ilmari Pyykkö, Jing Zou. Inner ear biocompatibility of lipid nanocapsules after round window membrane application. International journal of pharmaceutics. 2011 Feb; 404(1-2):211-9. doi: 10.1016/j.ijpharm.2010.11.006. [PMID: 21075187]
  • Alyaa Ramadan, Frederic Lagarce, Anne Tessier-Marteau, Olivier Thomas, Pierre Legras, Laurent Macchi, Patrick Saulnier, Jean Pierre Benoit. Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study. International journal of nanomedicine. 2011; 6(?):2941-51. doi: 10.2147/ijn.s25791. [PMID: 22162653]
  • Kazunori Iwanaga, Toru Sumizawa, Makoto Miyazaki, Masawo Kakemi. Characterization of organogel as a novel oral controlled release formulation for lipophilic compounds. International journal of pharmaceutics. 2010 Mar; 388(1-2):123-8. doi: 10.1016/j.ijpharm.2009.12.045. [PMID: 20045041]
  • Anne-Laure Fameau, Bérénice Houinsou-Houssou, Bruno Novales, Laurence Navailles, Frédéric Nallet, Jean-Paul Douliez. 12-Hydroxystearic acid lipid tubes under various experimental conditions. Journal of colloid and interface science. 2010 Jan; 341(1):38-47. doi: 10.1016/j.jcis.2009.09.034. [PMID: 19846108]
  • Zhipeng Huo, Songyuan Dai, Changneng Zhang, Fantai Kong, Xiaqin Fang, Lei Guo, Weiqing Liu, Linhua Hu, Xu Pan, Kongjia Wang. Low molecular mass organogelator based gel electrolyte with effective charge transport property for long-term stable quasi-solid-state dye-sensitized solar cells. The journal of physical chemistry. B. 2008 Oct; 112(41):12927-33. doi: 10.1021/jp8052168. [PMID: 18798664]
  • Eun-Ho Lee, Soo-Han Lee, Do-Yang Park, Kyoung-Ho Ki, Eun-Kyung Lee, Dong-Ho Lee, Gyu-Jeong Noh. Physicochemical properties, pharmacokinetics, and pharmacodynamics of a reformulated microemulsion propofol in rats. Anesthesiology. 2008 Sep; 109(3):436-47. doi: 10.1097/aln.0b013e318182a486. [PMID: 18719441]
  • Per E G Thorén, Olle Söderman, Sven Engström, Christian von Corswant. Interactions of novel, nonhemolytic surfactants with phospholipid vesicles. Langmuir : the ACS journal of surfaces and colloids. 2007 Jun; 23(13):6956-65. doi: 10.1021/la063700b. [PMID: 17516668]
  • Jean-Paul Douliez, Cédric Gaillard, Laurence Navailles, Frédéric Nallet. Novel lipid system forming hollow microtubes at high yields and concentration. Langmuir : the ACS journal of surfaces and colloids. 2006 Mar; 22(7):2942-5. doi: 10.1021/la053262t. [PMID: 16548537]
  • Jean-Paul Douliez. Cutin and suberin monomers are membrane perturbants. Journal of colloid and interface science. 2004 Mar; 271(2):507-10. doi: 10.1016/j.jcis.2003.12.020. [PMID: 14972629]