Tenuifoliside A (BioDeep_00000235816)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

NCGC00347659-02_C31H38O17_3-O-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-beta-D-fructofuranosyl 6-O-(4-hydroxybenzoyl)-alpha-D-glucopyranoside

化学式: C31H38O17 (682.2108898)
中文名称: 远志蔗糖酯A
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=CC(=C1OC)OC)\C=C\C(=O)O[C@H]2[C@H](O)[C@@H](CO)O[C@@]2(CO)O[C@H]3O[C@H](COC(=O)C4=CC=C(O)C=C4)[C@@H](O)[C@H](O)[C@H]3O
InChI: InChI=1S/C31H38O17/c1-41-18-10-15(11-19(42-2)27(18)43-3)4-9-22(35)46-28-24(37)20(12-32)47-31(28,14-33)48-30-26(39)25(38)23(36)21(45-30)13-44-29(40)16-5-7-17(34)8-6-16/h4-11,20-21,23-26,28,30,32-34,36-39H,12-14H2,1-3H3/b9-4+/t20-,21-,23-,24-,25+,26-,28+,30-,31+/m1/s1

描述信息

Tenuifoliside A is isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells[1].
Tenuifoliside A is isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells[1].
Tenuifoliside A is isolated from Polygala tenuifolia, has anti-apoptotic and antidepressant-like effects. Tenuifoliside A exhibits its neneurotrophic effects and promotes cell proliferation through the ERK/CREB/BDNF signal pathway in C6 cells[1].

同义名列表

2 个代谢物同义名

Tenuifoliside A; NCGC00347659-02_C31H38O17_3-O-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-beta-D-fructofuranosyl 6-O-(4-hydroxybenzoyl)-alpha-D-glucopyranoside

数据库引用编号

8 个数据库交叉引用编号

PubChem: 75242679
Metlin: METLIN985430
KNApSAcK: C00037899
CAS: 139726-35-5
MoNA: CCMSLIB00000853545
PMhub: MS000047434
medchemexpress: HY-N6076
LOTUS: LTS0191923

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

16 个相关的物种来源信息

2759 - Eukaryota: LTS0191923
3398 - Magnoliopsida: LTS0191923
33090 - Plants: -
4275 - Polygala: LTS0191923
690825 - Polygala sibirica: 10.1021/NP990084T
690825 - Polygala sibirica: LTS0191923
690825 - Polygala sibirica L.: -
355332 - Polygala tenuifolia: -
355332 - Polygala tenuifolia: 10.1248/BPB.27.1081
355332 - Polygala tenuifolia: 10.1248/CPB.39.2600
355332 - Polygala tenuifolia: LTS0191923
355332 - Polygala tenuifolia Willd.: -
4274 - Polygalaceae: LTS0191923
35493 - Streptophyta: LTS0191923
58023 - Tracheophyta: LTS0191923
33090 - Viridiplantae: LTS0191923

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Xin Zhao, Baoxin Xu, Peng Wu, Pan Zhao, Changchuan Guo, Yueli Cui, Yanxue Zhang, Xuelan Zhang, Huifen Li. UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma. Pharmaceutical biology. 2020 Dec; 58(1):969-978. doi: 10.1080/13880209.2020.1818790. [PMID: 32956609]
Xian-zhe Dong, Cui-li Huang, Bing-ying Yu, Yuan Hu, Li-hua Mu, Ping Liu. Effect of Tenuifoliside A isolated from Polygala tenuifolia on the ERK and PI3K pathways in C6 glioma cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Sep; 21(10):1178-88. doi: 10.1016/j.phymed.2014.04.022. [PMID: 24877714]