Telekin (BioDeep_00000235810)

PANOMIX_OTCML-2023

代谢物信息卡片

[3aR-(3aalpha,4aalpha,8abeta,9aalpha)]-Decahydro-4a-hydroxy-8a-methyl-3,5-bis(methylene)-naphtho[2,3-b]furan-2(3H)-one

化学式: C15H20O3 (248.14123700000002)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@@]2([C@@](C[C@@H]3[C@H]1C(=C)C(=O)O3)(CCCC2=C)C)O
InChI: InChI=1S/C15H20O3/c1-9-5-4-6-14(3)8-12-11(7-15(9,14)17)10(2)13(16)18-12/h11-12,17H,1-2,4-8H2,3H3/t11-,12-,14-,15-/m1/s1

描述信息

Telekin is a sesquiterpene lactone.
Telekin is a natural product found in Calea jamaicensis, Carpesium abrotanoides, and other organisms with data available.

同义名列表

8 个代谢物同义名

(3aR,4aR,8aR,9aR)-4a-hydroxy-8a-methyl-3,5-dimethylidene-4,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one; (3aR,4aR,8aR,9aR)-4a-hydroxy-8a-methyl-3,5-dimethylidene-4,6,7,8,9,9a-hexahydro-3aH-benzo[][1]benzouran-2-one; (3aR,4aR,8aR,9aR)-4a-Hydroxy-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one; 5alpha-Hydroxyeudesm-4(15),11(13)-dien-8beta,12-olide; Eudesmanolide; Telekin; [3aR-(3aalpha,4aalpha,8abeta,9aalpha)]-Decahydro-4a-hydroxy-8a-methyl-3,5-bis(methylene)-naphtho[2,3-b]furan-2(3H)-one; Telekine

数据库引用编号

7 个数据库交叉引用编号

ChEBI: CHEBI:181502
PubChem: 12443309
ChEMBL: CHEMBL406233
MeSH: telekin
KNApSAcK: C00012916
CAS: 6752-90-5
medchemexpress: HY-N10483

分类词条

倍半萜类

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

12 个相关的物种来源信息

637478 - Artemisia feddei: 10.1016/0031-9422(92)83460-G
2291100 - Artemisia lancea: 10.1016/0031-9422(92)83460-G
72353 - Artemisia splendens: 10.1016/S0031-9422(00)97692-1
72355 - Artemisia umbelliformis: 10.1016/S0031-9422(00)97692-1
1125166 - Calea jamaicensis: 10.1016/S0031-9422(00)97995-0
119172 - Carpesium abrotanoides:
2558930 - Carpesium faberi: 10.1016/J.BMCL.2010.10.138
557628 - Carpesium macrocephalum:
174463 - Helminthotheca echioides:
1548589 - Inula grandis: 10.1021/NP000211H
483693 - Inula racemosa: 10.1016/0031-9422(88)80100-6
56539 - Telekia speciosa: 10.1016/J.PHYTOL.2015.04.010

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Shuang Tang, Xin-Tian Zhang, Yun-Bao Ma, Xiao-Yan Huang, Chang-An Geng, Tian-Ze Li, Xue-Mei Zhang, Cheng Shen, Li-Hua Su, Zhen Gao, Ji-Jun Chen. Artemyrianolides A-S, Cytotoxic Sesquiterpenoids from Artemisia myriantha. Journal of natural products. 2020 09; 83(9):2618-2630. doi: 10.1021/acs.jnatprod.0c00396. [PMID: 32842729]
Chunfeng Xie, Lingmei Sun, Linghao Meng, Meicheng Wang, Jing Xu, Mark Bartlam, Yuanqiang Guo. Sesquiterpenes from Carpesium macrocephalum inhibit Candida albicans biofilm formation and dimorphism. Bioorganic & medicinal chemistry letters. 2015 Nov; 25(22):5409-11. doi: 10.1016/j.bmcl.2015.09.013. [PMID: 26394911]
Yan-Yan Ma, Deng-Gao Zhao, Kun Gao. Structural investigation and biological activity of sesquiterpene lactones from the traditional Chinese herb Inula racemosa. Journal of natural products. 2013 Apr; 76(4):564-70. doi: 10.1021/np300742d. [PMID: 23451797]
Xu-Wen Li, Liang Weng, Xue Gao, Yun Zhao, Fei Pang, Jian-Hui Liu, Hong-Feng Zhang, Jin-Feng Hu. Antiproliferative and apoptotic sesquiterpene lactones from Carpesium faberi. Bioorganic & medicinal chemistry letters. 2011 Jan; 21(1):366-72. doi: 10.1016/j.bmcl.2010.10.138. [PMID: 21109433]