vulpinic acid (BioDeep_00000231656)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


vulpinic acid

化学式: C19H14O5 (322.0841194)
中文名称: 吴耳酸
谱图信息: 最多检出来源 Viridiplantae(plant) 1.41%

分子结构信息

SMILES: C1(=O)C(=C(/C(=C(/c2ccccc2)\C(=O)OC)/O1)O)c1ccccc1
InChI: InChI=1S/C19H14O5/c1-23-18(21)15(13-10-6-3-7-11-13)17-16(20)14(19(22)24-17)12-8-4-2-5-9-12/h2-11,20H,1H3/b17-15+

描述信息

Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has?the?potential?for?atherosclerosis?research[1][2].

同义名列表

2 个代谢物同义名

vulpinic acid; NSC 5897



相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sang Ah Yi, Ki Hong Nam, Sil Kim, Hae Min So, Rhim Ryoo, Jeung-Whan Han, Ki Hyun Kim, Jaecheol Lee. Vulpinic Acid Controls Stem Cell Fate toward Osteogenesis and Adipogenesis. Genes. 2019 12; 11(1):. doi: 10.3390/genes11010018. [PMID: 31878002]
  • Béatrice Legouin, Françoise Lohézic-Le Dévéhat, Solenn Ferron, Isabelle Rouaud, Pierre Le Pogam, Laurence Cornevin, Michel Bertrand, Joël Boustie. Specialized Metabolites of the Lichen Vulpicida pinastri Act as Photoprotective Agents. Molecules (Basel, Switzerland). 2017 Jul; 22(7):. doi: 10.3390/molecules22071162. [PMID: 28704942]
  • Y Kwon, J Cha, J Chiang, G Tran, G Giaever, C Nislow, J-S Hur, Y-S Kwak. A chemogenomic approach to understand the antifungal action of Lichen-derived vulpinic acid. Journal of applied microbiology. 2016 Dec; 121(6):1580-1591. doi: 10.1111/jam.13300. [PMID: 27660105]
  • Gajendra Shrestha, Andrew Thompson, Richard Robison, Larry L St Clair. Letharia vulpina, a vulpinic acid containing lichen, targets cell membrane and cell division processes in methicillin-resistant Staphylococcus aureus. Pharmaceutical biology. 2016; 54(3):413-8. doi: 10.3109/13880209.2015.1038754. [PMID: 25919857]
  • Bruno Burlando, Elia Ranzato, Andrea Volante, Giovanni Appendino, Federica Pollastro, Luisella Verotta. Antiproliferative effects on tumour cells and promotion of keratinocyte wound healing by different lichen compounds. Planta medica. 2009 May; 75(6):607-13. doi: 10.1055/s-0029-1185329. [PMID: 19199230]
  • Daniel A Dias, Sylvia Urban. Chemical constituents of the lichen, Candelaria concolor: a complete NMR and chemical degradative investigation. Natural product research. 2009; 23(10):925-39. doi: 10.1080/14786410802682536. [PMID: 19521906]
  • Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Thirada Prajuabsuk, Kasem Soytong, Palangpon Kongsaeree, Apichart Suksamrarn. A bioactive triterpenoid and vulpinic acid derivatives from the mushroom Scleroderma citrinum. Planta medica. 2003 Jun; 69(6):568-71. doi: 10.1055/s-2003-40639. [PMID: 12865983]