Strychnine N-Oxide (BioDeep_00000231214)
natural product
代谢物信息卡片
化学式: C21H22N2O3 (350.163)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 94.12%
分子结构信息
SMILES: C1C[N+]2(CC3=CCOC4CC(=O)N5C6C4C3CC2C61C7=CC=CC=C75)[O-]
InChI: InChI=1S/C21H22N2O3/c24-18-10-16-19-13-9-17-21(6-7-23(17,25)11-12(13)5-8-26-16)14-3-1-2-4-15(14)22(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+,23?/m0/s1
描述信息
A tertiary amine oxide resulting from the oxidation of the non-acylated nitrogen of strychnine. It is a metabolite of strychnine.
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:132703
- PubChem: 73393
- Metlin: METLIN34472
- ChEMBL: CHEMBL138585
- KNApSAcK: C00037174
- CAS: 7248-28-4
- PMhub: MS000010144
- MetaboLights: MTBLC132703
- LOTUS: LTS0186850
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
25 个相关的物种来源信息
- 8782 - Aves: LTS0186850
- 7711 - Chordata: LTS0186850
- 2759 - Eukaryota: LTS0186850
- 26468 - Loganiaceae: LTS0186850
- 3398 - Magnoliopsida: LTS0186850
- 35493 - Streptophyta: LTS0186850
- 26496 - Strychnos: 10.1016/S0031-9422(02)00612-X
- 26496 - Strychnos: 10.1055/S-0029-1185387
- 26496 - Strychnos: LTS0186850
- 1040889 - Strychnos icaja: 10.1016/S0031-9422(02)00612-X
- 1040889 - Strychnos icaja: 10.1055/S-0029-1185387
- 1040889 - Strychnos icaja: LTS0186850
- 1037790 - Strychnos ignatii: 10.1055/S-2006-960910
- 1037790 - Strychnos ignatii: LTS0186850
- 403120 - Strychnos lucida: 10.1248/YAKUSHI1947.102.7_690
- 403120 - Strychnos lucida: LTS0186850
- 28545 - Strychnos nux-vomica: 10.1016/S0031-9422(00)91306-2
- 28545 - Strychnos nux-vomica: 10.1016/S0031-9422(02)00612-X
- 28545 - Strychnos nux-vomica: 10.1016/S0378-8741(03)00224-1
- 28545 - Strychnos nux-vomica: 10.1055/S-0029-1185387
- 28545 - Strychnos nux-vomica: 10.5246/JCPS.2012.02.025
- 28545 - Strychnos nux-vomica: LTS0186850
- 28545 - Strychnos nux-vomica: NA
- 58023 - Tracheophyta: LTS0186850
- 33090 - Viridiplantae: LTS0186850
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Bakhtiyar Qader, Issam Hussain, Mark Baron, Rafael Estevez-Brito, John Paul Cassella, Jose Gonzalez-Rodriguez. The Production and Evaluation of an Electrochemical Sensors for Strychnine and Its Main Metabolite Strychnine N-Oxide for Their Use in Biological Samples.
Molecules (Basel, Switzerland).
2022 Mar; 27(6):. doi:
10.3390/molecules27061826
. [PMID: 35335189] - Rixin Guo, Ting Wang, Guohong Zhou, Mengying Xu, Xiankuo Yu, Xiao Zhang, Feng Sui, Chun Li, Liying Tang, Zhuju Wang. Botany, Phytochemistry, Pharmacology and Toxicity of Strychnos nux-vomica L.: A Review.
The American journal of Chinese medicine.
2018; 46(1):1-23. doi:
10.1142/s0192415x18500015
. [PMID: 29298518] - Jun Guo, Hua Meng, Huang Huang Li, Qiao Feng Wang. Determination of strychnine, brucine, strychnine N-oxide, and brucine N-oxide in plasma samples after the oral administration of processed semen strychni extract by high-performance liquid chromatography with ultrasound-assisted mixed cloud point extraction.
Journal of separation science.
2016 Jul; 39(13):2553-61. doi:
10.1002/jssc.201501379
. [PMID: 27125604] - Yu Li, Xu Qi, Yu-Wei Yang, Yang Pan, Hui-Min Bian. Toxic effects of strychnine and strychnine N-oxide on zebrafish embryos.
Chinese journal of natural medicines.
2014 Oct; 12(10):760-7. doi:
10.1016/s1875-5364(14)60116-3
. [PMID: 25443369] - Yanhui Fu, Yu Zhang, Hongping He, Li Hou, Yingtong Di, Shunlin Li, Xiaodong Luo, Xiaojiang Hao. Strynuxlines A and B, alkaloids with an unprecedented carbon skeleton from Strychnos nux-vomica.
Journal of natural products.
2012 Nov; 75(11):1987-90. doi:
10.1021/np300339r
. [PMID: 23088673] - Xiao-yue Xu, Bao-chang Cai, Yang Pan, Tian-shan Wang. [Pharmacokinetics of the alkaloids from the processed seeds of Strychnos nux-vomica in rats].
Yao xue xue bao = Acta pharmaceutica Sinica.
2003 Jun; 38(6):458-61. doi:
NULL
. [PMID: 14513809] - Y He, M Wu, B Cai, P Zheng, Z Yuan. [Influence of different processing methods of four alkaloid contents in Strychnos nux-vomica L].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
1995 Feb; 20(2):84-6, 126. doi:
. [PMID: 7779278]