2-Isopropylphenol (BioDeep_00000023094)

   

human metabolite Endogenous natural product


代谢物信息卡片


1-Hydroxy-3-isopropylbenzene

化学式: C9H12O (136.08881019999998)
中文名称: 2-异丙基苯酚, 異丙苯酚
谱图信息: 最多检出来源 Homo sapiens(natural_products) 8%

分子结构信息

SMILES: CC(C)C1=CC=CC=C1O
InChI: InChI=1S/C9H12O/c1-7(2)8-5-3-4-6-9(8)10/h3-7,10H,1-2H3

描述信息

2-Isopropylphenol, also known as O-cumenol or O-hydroxycumene, belongs to the class of organic compounds known as cumenes. These are aromatic compounds containing a prop-2-ylbenzene moiety. 2-Isopropylphenol is a creosote, medicinal, and phenolic tasting compound. It has been detected in some species of the plant genus Haplopappus (PMID:10725607).
Flavouring ingredient

同义名列表

18 个代谢物同义名

1-Hydroxy-3-isopropylbenzene; 1-Hydroxy-2-isopropylbenzene; 2-(1-Methylethyl)phenol, 9ci; 2-(1-Methylethyl)-phenol; 2-(1-Methylethyl)phenol; Isopropylphenol, ortho; Ortho-isopropylphenol; 2-(Propan-2-yl)phenol; O-Isopropyl-phenol; 2-Isopropylphenol; 4-Isopropylphenol; O-Isopropylphenol; Isopropyl-phenol; O-Hydroxycumene; o-nitroaniline; Prodox 131; FEMA 3461; O-Cumenol



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

1 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

15 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Grace M S Yip, Zi-Wei Chen, Christopher J Edge, Edward H Smith, Robert Dickinson, Erhard Hohenester, R Reid Townsend, Karoline Fuchs, Werner Sieghart, Alex S Evers, Nicholas P Franks. A propofol binding site on mammalian GABAA receptors identified by photolabeling. Nature chemical biology. 2013 Nov; 9(11):715-20. doi: 10.1038/nchembio.1340. [PMID: 24056400]
  • Kevin A Harvey, Zhidong Xu, Phillip Whitley, V Jo Davisson, Rafat A Siddiqui. Characterization of anticancer properties of 2,6-diisopropylphenol-docosahexaenoate and analogues in breast cancer cells. Bioorganic & medicinal chemistry. 2010 Mar; 18(5):1866-74. doi: 10.1016/j.bmc.2010.01.045. [PMID: 20153203]
  • Hironori Tsuchiya, Takahiro Ueno, Toshiyuki Tanaka, Nobuyasu Matsuura, Maki Mizogami. Comparative study on determination of antioxidant and membrane activities of propofol and its related compounds. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2010 Jan; 39(1-3):97-102. doi: 10.1016/j.ejps.2009.11.001. [PMID: 19897032]
  • Yongnian Ni, Genlan Liu, Serge Kokot. Fluorescence spectrometric study on the interactions of Isoprocarb and sodium 2-isopropylphenate with bovine serum albumin. Talanta. 2008 Jul; 76(3):513-21. doi: 10.1016/j.talanta.2008.03.037. [PMID: 18585315]
  • Martin Barann, Isabelle Linden, Stefan Witten, Bernd W Urban. Molecular actions of propofol on human 5-HT3A receptors: enhancement as well as inhibition by closely related phenol derivatives. Anesthesia and analgesia. 2008 Mar; 106(3):846-57, table of contents. doi: 10.1213/ane.0b013e318162ca7c. [PMID: 18292429]