Reb D (BioDeep_00000230753)

 

Secondary id: BioDeep_00000018605, BioDeep_00000397959

PANOMIX_OTCML-2023


代谢物信息卡片


2-O-beta-D-glucopyranosyl-1-O-(13alpha-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose

化学式: C50H80O28 (1128.483588)
中文名称: 莱苞迪苷D, 莱苞迪甙D, 瑞鲍迪甙D
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC12CCCC(C1CCC34C2CCC(C3)(C(=C)C4)OC5C(C(C(C(O5)CO)O)OC6C(C(C(C(O6)CO)O)O)O)OC7C(C(C(C(O7)CO)O)O)O)(C)C(=O)OC8C(C(C(C(O8)CO)O)O)OC9C(C(C(C(O9)CO)O)O)O
InChI: InChI=1S/C50H80O28/c1-18-11-49-9-5-24-47(2,7-4-8-48(24,3)46(68)77-44-39(34(64)29(59)22(15-54)72-44)75-42-36(66)32(62)27(57)20(13-52)70-42)25(49)6-10-50(18,17-49)78-45-40(76-43-37(67)33(63)28(58)21(14-53)71-43)38(30(60)23(16-55)73-45)74-41-35(65)31(61)26(56)19(12-51)69-41/h19-45,51-67H,1,4-17H2,2-3H3/t19-,20-,21-,22-,23-,24+,25+,26-,27-,28-,29-,30-,31+,32+,33+,34+,35-,36-,37-,38+,39-,40-,41+,42+,43+,44+,45+,47-,48-,49-,50+/m1/s1

描述信息

Rebaudioside D is a rebaudioside that is rebaudioside A in which the hydroxy group at position 2 of the beta-D-glucosyl ester moiety has been converted to the corresponding beta-D-glucoside. Found in minute quantities in the leaves of Stevia rebaudiana. It has a role as a sweetening agent. It is a tetracyclic diterpenoid, a rebaudioside and a sophoroside. It is functionally related to a rebaudioside A, a rebaudioside E and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.
Rebaudioside D is a natural product found in Stevia rebaudiana with data available.
See also: Stevia rebaudiuna Leaf (part of).
A rebaudioside that is rebaudioside A in which the hydroxy group at position 2 of the beta-D-glucosyl ester moiety has been converted to the corresponding beta-D-glucoside. Found in minute quantities in the leaves of Stevia rebaudiana.
Rebaudioside D is a glycoside found in the leaves of Stevia rebaudiana and acts as a sweetener[1].
Rebaudioside D is a glycoside found in the leaves of Stevia rebaudiana and acts as a sweetener[1].

同义名列表

18 个代谢物同义名

2-O-beta-D-glucopyranosyl-1-O-(13alpha-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; 2-O-beta-D-glucopyranosyl-1-O-(13alpha-((beta-D-glucopyranosyl-(1->2)-(beta-D-glucopyranosyl-(1->3))-beta-D-glucopyranosyl)oxy)-18-oxo-5beta,8alpha,9beta,10alpha-kaur-16-en-18-yl)-beta-D-glucopyranose; KAUR-16-EN-18-OIC ACID, 13-((O-.BETA.-D-GLUCOPYRANOSYL-(1->2)-O-(.BETA.-D-GLUCOPYRANOSYL-(1->3))-.BETA.-D-GLUCOPYRANOSYL)OXY)-, 2-O-.BETA.-D-GLUCOPYRANOSYL-.BETA.-D-GLUCOPYRANOSYL ESTER, (4.ALPHA.)-; KAUR-16-EN-18-oic acid, 13-((o-beta-D-glucopyranosyl-(1->2)-O-(beta-D-glucopyranosyl-(1->3))-beta-D-glucopyranosyl)oxy)-, 2-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester, (4alpha)-; Kaur-16-en-18-oic acid, 13-[(O-?-D-glucopyranosyl-(1?2)-O-[?-D-glucopyranosyl-(1?3)]-?-D-glucopyranosyl)oxy]-, 2-O-?-D-glucopyranosyl-?-D-glucopyranosyl ester, (4?)-; Rebaudioside D; (4R)-13-[[2-O-(beta-D-Glucopyranosyl)-3-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyl ester; RPYRMTHVSUWHSV-CUZJHZIBSA-N; Rebaudioside D, (-)-; REBAUDIOSIDE D [MI]; (-)-Rebaudioside D; UNII-1SU114WXBX; Rebaudioside D; Rebaudioside-D; 1SU114WXBX; Reb-D; Reb D; RebD; JDO



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Arianne Morissette, Alice de Wouters d'Oplinter, Diana Majolli Andre, Marilou Lavoie, Bruno Marcotte, Thibault V Varin, Jocelyn Trottier, Geneviève Pilon, Martin Pelletier, Patrice D Cani, Olivier Barbier, Vanessa P Houde, André Marette. Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity. Scientific reports. 2024 02; 14(1):3077. doi: 10.1038/s41598-024-53587-y. [PMID: 38321177]
  • Yu Wang, Xue Sun, Xiaochen Jia, Liping Zhu, Heng Yin. Comparative transcriptomic of Stevia rebaudiana provides insight into rebaudioside D and rebaudioside M biosynthesis. Plant physiology and biochemistry : PPB. 2021 Oct; 167(?):541-549. doi: 10.1016/j.plaphy.2021.08.028. [PMID: 34425398]
  • Zhenyang Wang, Jiefang Hong, Siyuan Ma, Tong Huang, Yuanyuan Ma, Wei Liu, Wenbin Liu, Zhiming Liu, Hao Song. Heterologous expression of EUGT11 from Oryza sativa in Pichia pastoris for highly efficient one-pot production of rebaudioside D from rebaudioside A. International journal of biological macromolecules. 2020 Nov; 163(?):1669-1676. doi: 10.1016/j.ijbiomac.2020.09.132. [PMID: 32976903]
  • Liangliang Chen, Ping Sun, Fangfang Zhou, Yan Li, Kequan Chen, Honghua Jia, Ming Yan, Dachun Gong, Pingkai Ouyang. Synthesis of rebaudioside D, using glycosyltransferase UGTSL2 and in situ UDP-glucose regeneration. Food chemistry. 2018 Sep; 259(?):286-291. doi: 10.1016/j.foodchem.2018.03.126. [PMID: 29680056]
  • Indra Prakash, Cynthia Bunders, Krishna P Devkota, Romila D Charan, Catherine Ramirez, Maunik Parikh, Avetik Markosyan. Isolation and structure elucidation of rebaudioside D2 from bioconversion reaction of rebaudioside A to rebaudioside D. Natural product communications. 2014 Aug; 9(8):1135-8. doi: ". [PMID: 25233591]
  • Mohamed A Ibrahim, Douglas L Rodenburg, Kamilla Alves, Frank R Fronczek, James D McChesney, Chongming Wu, Brian J Nettles, Sylesh K Venkataraman, Frank Jaksch. Minor diterpene glycosides from the leaves of Stevia rebaudiana. Journal of natural products. 2014 May; 77(5):1231-5. doi: 10.1021/np4009656. [PMID: 24758242]
  • Andrey I Nikiforov, Marisa O Rihner, Alex K Eapen, Jennifer A Thomas. Metabolism and toxicity studies supporting the safety of rebaudioside D. International journal of toxicology. 2013 Jul; 32(4):261-73. doi: 10.1177/1091581813492828. [PMID: 23766392]
  • Karolina Jaworska, Alexander J Krynitsky, Jeanne I Rader. Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements. Journal of AOAC International. 2012 Nov; 95(6):1588-96. doi: 10.5740/jaoacint.11-435. [PMID: 23451373]