Nuezhenoside (BioDeep_00000230582)

   

PANOMIX_OTCML-2023


代谢物信息卡片


7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

化学式: C33H40O18 (724.221454)
中文名称: 紫草黄酮, 女贞苷
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 1.49%

分子结构信息

SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)OC6C(C(C(C(O6)C)O)O)O)O)O)O)O)O
InChI: InChI=1S/C33H40O18/c1-11-22(37)25(40)28(43)31(46-11)45-10-20-24(39)27(42)30(51-32-29(44)26(41)23(38)12(2)47-32)33(50-20)48-15-7-16(35)21-17(36)9-18(49-19(21)8-15)13-3-5-14(34)6-4-13/h3-9,11-12,20,22-35,37-44H,10H2,1-2H3/t11-,12-,20+,22-,23-,24+,25+,26+,27-,28+,29+,30+,31+,32-,33+/m0/s1

描述信息

Ligustroflavone is a natural product found in Ligustrum vulgare with data available.
Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1].
Ligustroflavone, extracted from Ligustrum lucidum, is a potential candidate as calcium-sensing receptor (CaSR) antagonist. Ligustroflavone exhibits protective effects against diabetic osteoporosis in mice[1].

同义名列表

6 个代谢物同义名

7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one; apigenin-7-O-beta-(2,6-di-alpha-rhamnopyranosyl)-glucopyranoside; Ligustroflavone(Nuezhenoside); Ligustroflavone; Nuezhenoside



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rong Kang, Wen Tian, Wei Cao, Yang Sun, Hui-Nan Zhang, Ying-Da Feng, Chen Li, Ze-Zhi Li, Xiao-Qiang Li. Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway. Chinese journal of natural medicines. 2021 Mar; 19(3):170-180. doi: 10.1016/s1875-5364(21)60018-3. [PMID: 33781450]
  • Rui Feng, Fan Ding, Xiu-Hua Mi, Shu-Fen Liu, Ai-Ling Jiang, Bi-Hui Liu, Yin Lian, Qi Shi, Yong-Jun Wang, Yan Zhang. Protective Effects of Ligustroflavone, an Active Compound from Ligustrum lucidum, on Diabetes-Induced Osteoporosis in Mice: A Potential Candidate as Calcium-Sensing Receptor Antagonist. The American journal of Chinese medicine. 2019; 47(2):457-476. doi: 10.1142/s0192415x1950023x. [PMID: 30834778]
  • Ying Nie, Weifeng Yao. A Comprehensive Quality Evaluation Method Based on C30-HPLC and an Analytic Hierarchy Process for the Chinese Herbal Formula, Erzhiwan. Molecules (Basel, Switzerland). 2018 Aug; 23(8):. doi: 10.3390/molecules23082045. [PMID: 30111749]
  • Hong Liu, Cheng Xu, Wei Wang, Yue Zhao. Development and Validation of an LC-ESI-MS/MS Method for Simultaneous Determination of Ligustroflavone and Rhoifolin in Rat Plasma and Its Application to a Pharmacokinetic Study. Journal of chromatographic science. 2017 03; 55(3):267-274. doi: 10.1093/chromsci/bmw181. [PMID: 27884870]
  • Yong-Tong An, Peng Zhu, Yan Zhong, Yu-Chen Sheng, Zhen Zhao, Yang Min, Yu-Ye Xia. A neuroprotective mechanism of YGY-E in cerebral ischemic injury in rats. CNS neuroscience & therapeutics. 2012 Jan; 18(1):14-20. doi: 10.1111/j.1755-5949.2011.00277.x. [PMID: 22280158]
  • A Pieroni, P Pachaly, Y Huang, B Van Poel, A J Vlietinck. Studies on anti-complementary activity of extracts and isolated flavones from Ligustrum vulgare and Phillyrea latifolia leaves (Oleaceae). Journal of ethnopharmacology. 2000 Jun; 70(3):213-7. doi: 10.1016/s0378-8741(99)00169-5. [PMID: 10837985]
  • A Pieroni, P Pachaly. Isolation and structure elucidation of ligustroflavone, a new apigenin triglycoside from the leaves of Ligustrum vulgare L. Die Pharmazie. 2000 Jan; 55(1):78-80. doi: ". [PMID: 10683879]