2-galloylhyperin (BioDeep_00000230496)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C28H24O16 (616.1064)
中文名称: 2''-O-没食子酰基金丝桃苷, 2”-O-没食子酰基金丝桃苷, 2-O-没食子酰基金丝桃苷
谱图信息:
最多检出来源 Escherichia coli(natural_products) 100%
分子结构信息
SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O)O)O
InChI: InChI=1S/C28H24O16/c29-8-18-21(37)23(39)26(43-27(40)10-4-15(34)20(36)16(35)5-10)28(42-18)44-25-22(38)19-14(33)6-11(30)7-17(19)41-24(25)9-1-2-12(31)13(32)3-9/h1-7,18,21,23,26,28-37,39H,8H2/t18-,21+,23+,26-,28+/m1/s1
描述信息
2-galloylhyperin is a member of flavonoids and a glycoside.
2-O-galloylhyperin is a natural product found in Mosquitoxylum jamaicense, Euphorbia esula, and other organisms with data available.
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage[1][2].
2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage[1][2].
同义名列表
13 个代谢物同义名
(2S,3R,4S,5R,6R)-2-((2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl 3,4,5-trihydroxybenzoate; (2S,3R,4S,5R,6R)-2-(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yloxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl 3,4,5-trihydroxybenzoate; [(2S,3R,4S,5R,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxochromen-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 3,4,5-trihydroxybenzoate; Benzoic acid, 3,4,5-trihydroxy-, 2-ester with 2-(3,4-dihydroxyphenyl)-3-(beta-D-glucopyransyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[2-O-(3,4,5-trihydroxybenzoyl)-b-D-galactopyranosyl]oxy]-; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl 2-O-(3,4,5-trihydroxybenzoyl)hexopyranoside; Quercetin-3-O-(2-galloyl)-beta-D-galactopyranoside; Quercetin 3-O-(2-galloyl)-beta-D-galactopyranoside; Quercetin 3-beta-galactoside-2-gallate; 2'-O-Galloylhyperin; 2"-O-Galloylhyperin; 2-O-Galloylhyperin; 2-galloylhyperin
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:190973
- PubChem: 6453359
- ChEMBL: CHEMBL505880
- LipidMAPS: LMPK12112071
- MeSH: 2-galloylhyperin
- ChemIDplus: 0053209271
- chemspider: 4955742
- CAS: 56552-82-0
- CAS: 53209-27-1
- medchemexpress: HY-N0526
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 33090 - Plants: -
- 33090 - 覆盆子: -
- 33090 - 鹿衔草: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Sun-Dong Zhang, Peng Wang, Jing Zhang, Wei Wang, Li-Ping Yao, Cheng-Bo Gu, Thomas Efferth, Yu-Jie Fu. 2'O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo.
Chemico-biological interactions.
2019 May; 304(?):20-27. doi:
10.1016/j.cbi.2019.02.029
. [PMID: 30849337] - Peng Wang, Yi-Meng Gao, Xing Sun, Na Guo, Ji Li, Wei Wang, Li-Ping Yao, Yu-Jie Fu. Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Apr; 102(?):129-142. doi:
10.1016/j.fct.2017.02.016
. [PMID: 28213291] - Dong-Yang Zhang, Xiao-Hui Yao, Ming-Hui Duan, Meng Luo, Chun-Jian Zhao, Yuan-Gang Zu, Yu-Jie Fu. An effective homogenate-assisted negative pressure cavitation extraction for the determination of phenolic compounds in pyrola by LC-MS/MS and the evaluation of its antioxidant activity.
Food & function.
2015 Oct; 6(10):3323-33. doi:
10.1039/c5fo00727e
. [PMID: 26256648] - Xiao-Hui Yao, Dong-Yang Zhang, Meng Luo, Shuang Jin, Yuan-Gang Zu, Thomas Efferth, Yu-Jie Fu. Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2'-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity.
Food chemistry.
2015 Feb; 169(?):270-6. doi:
10.1016/j.foodchem.2014.07.115
. [PMID: 25236226] - Donghui Zhou, Yuanzhe Jin, Fengchen Yao, Zhiying Duan, Qi Wang, Jing Liu. Validated LC-MS/MS method for the simultaneous determination of hyperoside and 2''-O-galloylhyperin in rat plasma: application to a pharmacokinetic study in rats.
Biomedical chromatography : BMC.
2014 Aug; 28(8):1057-63. doi:
10.1002/bmc.3117
. [PMID: 24375731] - H J Kim, E R Woo, C G Shin, H Park. A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase.
Journal of natural products.
1998 Jan; 61(1):145-8. doi:
10.1021/np970171q
. [PMID: 9461665]