Corylinin (BioDeep_00000230117)

   

PANOMIX_OTCML-2023


代谢物信息卡片


3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one

化学式: C25H26O4 (390.18309960000005)
中文名称: 次苷酸查尔酮, 3-[3-[(2E)-3,7-二甲基-2,6-辛二烯-1-基]-4-羟基苯基]-7-羟基-4H-1-苯并吡喃-4-酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CCCC(=CCC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)C)C
InChI: InChI=1S/C25H26O4/c1-16(2)5-4-6-17(3)7-8-19-13-18(9-12-23(19)27)22-15-29-24-14-20(26)10-11-21(24)25(22)28/h5,7,9-15,26-27H,4,6,8H2,1-3H3/b17-7+

描述信息

Corylifol A is a natural product found in Aspergillus flocculosus and Cullen corylifolium with data available.
Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC50 of 0.81 μM.
Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC50 of 0.81 μM.

同义名列表

6 个代谢物同义名

3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one; 7,4-dihydroxy-3-[(e)-3,7-dimethyl2,6-octadienyl] isoflavone; 3-Geranyl-4,7-dihydroxyisoflavone; Corylifol A; Corylinin; Corylifol-A



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zhi-Xing Zhou, Li Yang, Li-Yuan Cheng, Ying-Li Yu, Lei Song, Kun Zhou, Ying-Liang Wu, Yue Zhang. Simultaneous characterization of multiple Psoraleae Fructus bioactive compounds in rat plasma by ultra-high-performance liquid chromatography coupled with triple quadrupole mass spectrometry for application in sex-related differences in pharmacokinetics. Journal of separation science. 2020 Jul; 43(14):2804-2816. doi: 10.1002/jssc.202000286. [PMID: 32384213]
  • Yeongeun Han, Hyejin Lee, Hua Li, Jae-Ha Ryu. Corylifol A from Psoralea corylifolia L. Enhances Myogenesis and Alleviates Muscle Atrophy. International journal of molecular sciences. 2020 Feb; 21(5):. doi: 10.3390/ijms21051571. [PMID: 32106603]
  • Xin-Xin Wang, Xia Lv, Shi-Yang Li, Jie Hou, Jing Ning, Jia-Yue Wang, Yun-Feng Cao, Guang-Bo Ge, Bin Guo, Ling Yang. Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi). Toxicology and applied pharmacology. 2015 Nov; 289(1):70-8. doi: 10.1016/j.taap.2015.09.003. [PMID: 26348140]
  • Seung Woong Lee, Bo Ra Yun, Mi Hwa Kim, Chan Sun Park, Woo Song Lee, Hyun-Mee Oh, Mun-Chual Rho. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta medica. 2012 Jun; 78(9):903-6. doi: 10.1055/s-0031-1298482. [PMID: 22573369]
  • D Xin, H Wang, J Yang, Y-F Su, G-W Fan, Y-F Wang, Y Zhu, X-M Gao. Phytoestrogens from Psoralea corylifolia reveal estrogen receptor-subtype selectivity. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2010 Feb; 17(2):126-31. doi: 10.1016/j.phymed.2009.05.015. [PMID: 19577453]