Incensole (BioDeep_00000230015)
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C22H36O3 (348.2664)
中文名称: 乙酰因香酚, 醋酸因香酚, 因香酚乙酸酯
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 92%
分子结构信息
SMILES: CC([C@@]12C/C=C(C)/CC/C=C(C)/CC[C@H](OC(C)=O)[C@@](O2)(C)CC1)C
InChI: InChI=1S/C22H36O3/c1-16(2)22-13-12-18(4)9-7-8-17(3)10-11-20(24-19(5)23)21(6,25-22)14-15-22/h8,12,16,20H,7,9-11,13-15H2,1-6H3/b17-8+,18-12+/t20-,21+,22+/m0/s1
描述信息
Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1].
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Satya Kumar Avula, Ajmal Khan, Sobia Ahsan Halim, Najeeb Ur Rehman, Nasiara Karim, Imran Khan, Rene Csuk, Biswanath Das, Ahmed Al-Harrasi. Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi- incensole acetate in chronic unpredictable mild stress model of depression; behavioural and biochemical correlates.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Dec; 156(?):113960. doi:
10.1016/j.biopha.2022.113960
. [PMID: 36411640] - William N Setzer. Conformational analysis of macrocyclic frankincense (Boswellia) diterpenoids.
Journal of molecular modeling.
2018 Mar; 24(3):74. doi:
10.1007/s00894-018-3625-8
. [PMID: 29492734] - Jin Ren, Yan-Gai Wang, Ai-Guo Wang, Lian-Qiu Wu, Hai-Jing Zhang, Wen-Jie Wang, Ya-Lun Su, Hai-Lin Qin. Cembranoids from the Gum Resin of Boswellia carterii as Potential Antiulcerative Colitis Agents.
Journal of natural products.
2015 Oct; 78(10):2322-31. doi:
10.1021/acs.jnatprod.5b00104
. [PMID: 26457560] - Diana C Rueda, Melanie Raith, Maria De Mieri, Angela Schöffmann, Steffen Hering, Matthias Hamburger. Identification of dehydroabietc acid from Boswellia thurifera resin as a positive GABAA receptor modulator.
Fitoterapia.
2014 Dec; 99(?):28-34. doi:
10.1016/j.fitote.2014.09.002
. [PMID: 25200370] - Sami I Ali, Chuan-Rui Zhang, Amal A Mohamed, Farouk K El-Baz, Ahmad K Hegazy, Maimona A Kord, Muraleedharan G Nair. Major constituents of Boswellia carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity.
Natural product communications.
2013 Oct; 8(10):1365-6. doi:
. [PMID: 24354175]
- Mukhtar Ahmed, Nasser Al-Daghri, Abdul Halim Harrath, Majed S Alokail, Ravindranath H Aladakatti, Mukhtar Ahmed G Ghodesawar, Saleh Alwasel. Potential ultrastructural changes in rat epididymal cell types induced by Boswellia papyrifera and Boswellia carterii incense.
Comptes rendus biologies.
2013 Aug; 336(8):392-9. doi:
10.1016/j.crvi.2013.04.004
. [PMID: 24018196] - Arieh Moussaieff, Moshe Gross, Elimelech Nesher, Tatiana Tikhonov, Gal Yadid, Albert Pinhasov. Incensole acetate reduces depressive-like behavior and modulates hippocampal BDNF and CRF expression of submissive animals.
Journal of psychopharmacology (Oxford, England).
2012 Dec; 26(12):1584-93. doi:
10.1177/0269881112458729
. [PMID: 23015543] - Michael Paul, Gerit Brüning, Jochen Bergmann, Johann Jauch. A thin-layer chromatography method for the identification of three different olibanum resins (Boswellia serrata, Boswellia papyrifera and Boswellia carterii, respectively, Boswellia sacra).
Phytochemical analysis : PCA.
2012 Mar; 23(2):184-9. doi:
10.1002/pca.1341
. [PMID: 21858880] - Arieh Moussaieff, Raphael Mechoulam. Boswellia resin: from religious ceremonies to medical uses; a review of in-vitro, in-vivo and clinical trials.
The Journal of pharmacy and pharmacology.
2009 Oct; 61(10):1281-93. doi:
10.1211/jpp/61.10.0003
. [PMID: 19814859]