Myrigalone A (BioDeep_00000022971)

   

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


2,2,4-Trimethyl-6-(1-oxo-3-phenylpropyl)-1,3,5-cyclohexanetrione

化学式: C18H20O4 (300.13615200000004)
中文名称:
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 32%

分子结构信息

SMILES: C1(=O)[C@@H](C(=O)[C@H](C(=O)C1(C)C)C(=O)CCc1ccccc1)C
InChI: InChI=1S/C18H20O4/c1-11-15(20)14(17(22)18(2,3)16(11)21)13(19)10-9-12-7-5-4-6-8-12/h4-8,11,14H,9-10H2,1-3H3

描述信息

Myrigalone A is found in herbs and spices. Myrigalone A is isolated from Myrica gale (bog myrtle).
Isolated from Myrica gale (bog myrtle). Myrigalone A is found in herbs and spices.

同义名列表

3 个代谢物同义名

2,2,4-Trimethyl-6-(1-oxo-3-phenylpropyl)-1,3,5-cyclohexanetrione; 2,2,4-trimethyl-6-(3-phenylpropanoyl)cyclohexane-1,3,5-trione; Myrigalone A



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kazumi Nakabayashi, Matthew Walker, Dianne Irwin, Jonathan Cohn, Stephanie M Guida-English, Lucio Garcia, Iva Pavlović, Ondřej Novák, Danuše Tarkowská, Miroslav Strnad, Marta Pérez, Anne Seville, David Stock, Gerhard Leubner-Metzger. The Phytotoxin Myrigalone A Triggers a Phased Detoxification Programme and Inhibits Lepidium sativum Seed Germination via Multiple Mechanisms including Interference with Auxin Homeostasis. International journal of molecular sciences. 2022 Apr; 23(9):. doi: 10.3390/ijms23094618. [PMID: 35563008]
  • Daniel P Killeen, Lesley Larsen, Franck E Dayan, Keith C Gordon, Nigel B Perry, John W van Klink. Nortriketones: Antimicrobial Trimethylated Acylphloroglucinols from Ma̅nuka (Leptospermum scoparium). Journal of natural products. 2016 Mar; 79(3):564-9. doi: 10.1021/acs.jnatprod.5b00968. [PMID: 26731565]
  • Antje Voegele, Kai Graeber, Krystyna Oracz, Danuše Tarkowská, Dominique Jacquemoud, Veronika Turečková, Terezie Urbanová, Miroslav Strnad, Gerhard Leubner-Metzger. Embryo growth, testa permeability, and endosperm weakening are major targets for the environmentally regulated inhibition of Lepidium sativum seed germination by myrigalone A. Journal of experimental botany. 2012 Sep; 63(14):5337-50. doi: 10.1093/jxb/ers197. [PMID: 22821938]
  • Krystyna Oracz, Antje Voegele, Danuse Tarkowská, Dominique Jacquemoud, Veronika Turecková, Terezie Urbanová, Miroslav Strnad, Elwira Sliwinska, Gerhard Leubner-Metzger. Myrigalone A inhibits Lepidium sativum seed germination by interference with gibberellin metabolism and apoplastic superoxide production required for embryo extension growth and endosperm rupture. Plant & cell physiology. 2012 Jan; 53(1):81-95. doi: 10.1093/pcp/pcr124. [PMID: 21908442]
  • Jean Popovici, Cedric Bertrand, Dominique Jacquemoud, Floriant Bellvert, Maria P Fernandez, Gilles Comte, Florence Piola. An allelochemical from Myrica gale with strong phytotoxic activity against highly invasive Fallopia x bohemica taxa. Molecules (Basel, Switzerland). 2011 Mar; 16(3):2323-33. doi: 10.3390/molecules16032323. [PMID: 21394077]
  • L Mathiesen, K E Malterud, R B Sund. Antioxidant activity of fruit exudate and C-methylated dihydrochalcones from Myrica gale. Planta medica. 1995 Dec; 61(6):515-8. doi: 10.1055/s-2006-959360. [PMID: 8824944]