Glycerol 1-myristate (BioDeep_00000229584)
Main id: BioDeep_00000396456
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C17H34O4 (302.2456964)
中文名称: 单豆蔻酸甘油酯, 豆蔻酸甘油酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCC(=O)OCC(CO)O
InChI: InChI=1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16,18-19H,2-15H2,1H3
描述信息
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
1-Monomyristin, extracted from Serenoa repens, inhibits the hydrolysis of 2-oleoylglycerol (IC50=32 μM) and fatty acid amide hydrolase (FAAH) activity (IC50=18 μM). 1-Monomyristin shows antibacterial activity against Staphylococcus aureus and Aggregatibacter actinomycetemcomitans and also antifungal activity against Candida albicans[1][2][3].
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:75567
- ChEBI: CHEBI:75562
- PubChem: 79050
- HMDB: HMDB0304951
- ChEMBL: CHEMBL463092
- CAS: 27214-38-6
- CAS: 589-68-4
- medchemexpress: HY-N2512
分类词条
相关代谢途径
Reactome(4)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products.
ACS pharmacology & translational science.
2023 May; 6(5):683-701. doi:
10.1021/acsptsci.2c00194. [PMID: 37200814] - Arumugam Rajavelu, Zumrad Tulyasheva, Rakesh Jaiswal, Albert Jeltsch, Nikolai Kuhnert. The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols.
BMC biochemistry.
2011 Apr; 12(?):16. doi:
10.1186/1471-2091-12-16. [PMID: 21510884] - Sheref S Mansy. Model protocells from single-chain lipids.
International journal of molecular sciences.
2009 Mar; 10(3):835-843. doi:
10.3390/ijms10030835. [PMID: 19399223] - Tajuddin, Shamshad Ahmad, Abdul Latif, Iqbal Ahmad Qasmi, Kunwar Mohammad Yusuf Amin. An experimental study of sexual function improving effect of Myristica fragrans Houtt. (nutmeg).
BMC complementary and alternative medicine.
2005 Jul; 5(?):16. doi:
10.1186/1472-6882-5-16. [PMID: 16033651] - Tomoko Konishi, Hideo Satsu, Yasuo Hatsugai, Koichi Aizawa, Takahiro Inakuma, Shinji Nagata, Sho-Hei Sakuda, Hiromichi Nagasawa, Makoto Shimizu. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells.
British journal of pharmacology.
2004 Oct; 143(3):379-87. doi:
10.1038/sj.bjp.0705804. [PMID: 15351776] - S Juglal, R Govinden, B Odhav. Spice oils for the control of co-occurring mycotoxin-producing fungi.
Journal of food protection.
2002 Apr; 65(4):683-7. doi:
10.4315/0362-028x-65.4.683. [PMID: 11952220]