Arginine hydrochloride (BioDeep_00000228166)
Secondary id: BioDeep_00000858758, BioDeep_00001871649
human metabolite PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C6H15ClN4O2 (210.088348)
中文名称: L-精氨酸盐酸盐
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 15.65%
分子结构信息
SMILES: C(CC(C(=O)O)N)CN=C(N)N.Cl
InChI: 1H/t4-
描述信息
Dietary supplement, nutrient. Arginine (abbreviated as Arg or R) is an alpha-amino acid. The L-form is one of the 20 most common natural amino acids.
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05X - I.v. solution additives > B05XB - Amino acids
Dietary supplement, nutrient
L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
同义名列表
18 个代谢物同义名
(2S)-2-amino-5-carbamimidamidopentanoic acid hydrochloride; DL-Arginine acetate, monohydrate; DL Arginine acetate, monohydrate; Monohydrate DL-arginine acetate; L-(+)-Arginine Hydrochloride; L-Arginine hydrochloride; Hydrochloride, arginine; Arginine hydrochloride; Arginine, L isomer; Arginine, L-isomer; L-Isomer arginine; L-Arginine; L Arginine; R-Gene 10; Arginine; R-Gene; (S)-(+)-Arginine hydrochloride; L-Arginine (hydrochloride)
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:31235
- PubChem: 66250
- HMDB: HMDB0303361
- DrugBank: DBSALT000869
- ChEMBL: CHEMBL1200381
- MeSH: Arginine
- foodb: FDB011914
- chemspider: 59634
- CAS: 15595-35-4
- CAS: 1119-34-2
- medchemexpress: HY-N0455A
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Jialing Cao, Rong Tsao, Cheng Yang, Lianfu Zhang. Aqueous preparation of arginyl-fructosyl-glucose (a maltose-arginine AC) and determination of Amadori compounds (ACs) in red ginseng by ultra-high performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS).
Food research international (Ottawa, Ont.).
2024 Jul; 187(?):114436. doi:
10.1016/j.foodres.2024.114436
. [PMID: 38763683] - Zibian Fan, Wei Jia. High-confidence structural annotation of substances via multi-layer molecular network reveals the system-wide constituent alternations in milk interfered with diphenylolpropane.
Journal of hazardous materials.
2024 Jun; 471(?):134334. doi:
10.1016/j.jhazmat.2024.134334
. [PMID: 38642498] - Yamila Carla Agrofoglio, María José Iglesias, Soledad Perez-Santángelo, María José de Leone, Tino Koester, Rafael Catalá, Julio Salinas, Marcelo J Yanovsky, Dorothee Staiger, Julieta L Mateos. Arginine methylation of SM-LIKE PROTEIN 4 antagonistically affects alternative splicing during Arabidopsis stress responses.
The Plant cell.
2024 May; 36(6):2219-2237. doi:
10.1093/plcell/koae051
. [PMID: 38518124] - Eleonora Bailoni, Miyer F Patiño-Ruiz, Andreea R Stan, Gea K Schuurman-Wolters, Marten Exterkate, Arnold J M Driessen, Bert Poolman. Synthetic Vesicles for Sustainable Energy Recycling and Delivery of Building Blocks for Lipid Biosynthesis†.
ACS synthetic biology.
2024 May; 13(5):1549-1561. doi:
10.1021/acssynbio.4c00073
. [PMID: 38632869] - Yuzhu Xu, Menghe Huang, Yingting Chen, Lintao Yu, Meiran Wu, Shiyue Kang, Qiuyu Lin, Qiaoxuan Zhang, Liqiao Han, Haibiao Lin, Peifeng Ke, Wenjin Fu, Qizhi Tang, Jun Yan, Xianzhang Huang. Development of simultaneous quantitation method for 20 free advanced glycation end products using UPLC-MS/MS and clinical application in kidney injury.
Journal of pharmaceutical and biomedical analysis.
2024 May; 242(?):116035. doi:
10.1016/j.jpba.2024.116035
. [PMID: 38367518] - Xiao Han, Jingpiao Bao, Jianbo Ni, Bin Li, Pengli Song, Rong Wan, Xingpeng Wang, Guoyong Hu, Congying Chen. Qing Xia Jie Yi Formula granules alleviated acute pancreatitis through inhibition of M1 macrophage polarization by suppressing glycolysis.
Journal of ethnopharmacology.
2024 May; 325(?):117750. doi:
10.1016/j.jep.2024.117750
. [PMID: 38216100] - Louisa Schlaak, Christoph Weise, Benno Kuropka, Alexander Weng. Mutational Analysis of RIP Type I Dianthin-30 Suggests a Role for Arg24 in Endocytosis.
Toxins.
2024 May; 16(5):. doi:
10.3390/toxins16050219
. [PMID: 38787071] - Teresa Janas, Karolina Sapoń, Tadeusz Janas. Selection of bifunctional RNAs with specificity for arginine and lipid membranes.
FEBS letters.
2024 May; 598(9):1061-1079. doi:
10.1002/1873-3468.14880
. [PMID: 38649155] - Ludan Cao, Guo Wang, Xiuxu Ye, Fang Li, Shujun Wang, Huanling Li, Peng Wang, Jiabao Wang. Physiological, Metabolic, and Transcriptomic Analyses Reveal Mechanisms of Proliferation and Somatic Embryogenesis of Litchi (Litchi chinensis Sonn.) Embryogenic Callus Promoted by D-Arginine Treatment.
International journal of molecular sciences.
2024 Apr; 25(7):. doi:
10.3390/ijms25073965
. [PMID: 38612774] - Youssef A Attia, Ahmed A Abdallah, Fulvia Bovera, Abd El-Hamid E Abd El-Hamid, Asmaa Sh El-Naggar, Rashed A Alhotan, Vincenzo Tufarelli, Reda M Zaki. Effect of dietary electrolyte balance and arginine to lysine ratio on hematological, antioxidant and immunological traits in dual-purpose breeding hens under cyclic heat stress condition.
Journal of thermal biology.
2024 Apr; 121(?):103835. doi:
10.1016/j.jtherbio.2024.103835
. [PMID: 38531186] - Jing Wenguang, Lin Xiaoyu, L I Chu, Zhao Xiaoliang, Cheng Xianlong, Wang Penglong, Wei Feng, M A Shuangcheng. Anti-inflammatory mechanism of the non-volatile ingredients originated from Guanghuoxiang () based on high performance liquid chromatography-heated electron spray ionization-high resolution mass spectroscope and cell metabolomics.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2024 Apr; 44(2):260-267. doi:
10.19852/j.cnki.jtcm.20240203.003
. [PMID: 38504532] - Bojiao Yi, Yurou Zhao, Han Yan, Zeyu Li, Pin Zhang, Zhengyu Fang, Yuping Zhao, Hongjun Yang, Na Guo. Targeted arginine metabolomics combined with metagenomics revealed the potential mechanism of Pueraria lobata extract in treating myocardial infarction.
Journal of chromatography. A.
2024 Mar; 1719(?):464732. doi:
10.1016/j.chroma.2024.464732
. [PMID: 38387153] - Nidhin Thomas, Wesley Combs, Kranthi K Mandadapu, Ashutosh Agrawal. Preferential electrostatic interactions of phosphatidic acid with arginines.
Soft matter.
2024 Mar; 20(13):2998-3006. doi:
10.1039/d4sm00088a
. [PMID: 38482724] - Huijeong Ahn, Geun-Shik Lee. Amino Sugar-Enriched Fraction of Korean Red Ginseng Extract Induces the Priming Step of NLRP3 Inflammasome.
Molecules (Basel, Switzerland).
2024 Mar; 29(7):. doi:
10.3390/molecules29071455
. [PMID: 38611734] - Clément Barre-Villeneuve, Michèle Laudié, Marie-Christine Carpentier, Lauriane Kuhn, Thierry Lagrange, Jacinthe Azevedo-Favory. The unique dual targeting of AGO1 by two types of PRMT enzymes promotes phasiRNA loading in Arabidopsis thaliana.
Nucleic acids research.
2024 Mar; 52(5):2480-2497. doi:
10.1093/nar/gkae045
. [PMID: 38321923] - Guoshu Bi, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Yiwei Huang, Tao Lu, Huan Zhang, Xing Jin, Zhencong Chen, Mengnan Zhao, Hong Fan, Qun Wang, Boyi Gan, Cheng Zhan. Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer.
Nature communications.
2024 Mar; 15(1):2461. doi:
10.1038/s41467-024-46776-w
. [PMID: 38504107] - Subhasis Mandal, Suman Mallik, Avinandan Bhoumick, Anindita Bhattacharya, Prosenjit Sen. Synthesis of Amino Acid-Based Cationic Lipids and Study of the Role of the Cationic Head Group for Enhanced Drug and Nucleic Acid Delivery.
Chembiochem : a European journal of chemical biology.
2024 03; 25(6):e202300834. doi:
10.1002/cbic.202300834
. [PMID: 38284327] - Noriaki Katayama, Takashi Osanai. Arginine inhibits the arginine biosynthesis rate-limiting enzyme and leads to the accumulation of intracellular aspartate in Synechocystis sp. PCC 6803.
Plant molecular biology.
2024 Mar; 114(2):27. doi:
10.1007/s11103-024-01416-1
. [PMID: 38478146] - Yajing Kong, Xiaolin Cai, Yimeng Li, Runyang Sun, Hui Yang, Tongyu Jiang, Shuai Cheng, Luyi Song, Baowei Yang, Chunling Zhang, Chao Shi. Synergistic bactericidal effect and mechanism of ultrasound combined with Lauroyl Arginate Ethyl against Salmonella Typhimurium and its application in the preservation of onions.
International journal of food microbiology.
2024 Mar; 413(?):110611. doi:
10.1016/j.ijfoodmicro.2024.110611
. [PMID: 38308880] - Xiao-Chun Guo, Shao-Yong Lu, Sheng-Nan Zhang, Ping Xie, Guang-Yu Li, Zu-Qin Shi, Yi-Tong Zhou, Yu-Meng Wang. Combined inhibitory effects of microcystin-LR and microcystin-RR on growth and development in zebrafish larvae.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2024 Mar; 277(?):109824. doi:
10.1016/j.cbpc.2023.109824
. [PMID: 38154657] - Peiwei Li, Chugang Mei, Sayed Haidar Abbas Raza, Gong Cheng, Yue Ning, Le Zhang, Linsen Zan. Arginine (315) is required for the PLIN2-CGI-58 interface and plays a functional role in regulating nascent LDs formation in bovine adipocytes.
Genomics.
2024 Mar; 116(2):110817. doi:
10.1016/j.ygeno.2024.110817
. [PMID: 38431031] - Shujin Wang, Yinying Han, Ruimin Liu, Mengqian Hou, Dietbert Neumann, Jun Zhang, Fang Wang, Yumeng Li, Xueya Zhao, Francesco Schianchi, Chao Dai, Lizhong Liu, Miranda Nabben, Jan F C Glatz, Xin Wu, Xifeng Lu, Xi Li, Joost J F P Luiken. Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis.
Circulation research.
2024 03; 134(5):505-525. doi:
10.1161/circresaha.123.322910
. [PMID: 38422177] - Yan Yang, Yushan Yang, Jingsi Jiang, Zongzhou Wu, Jiuyuan Sun, Hui Zhi, ShiYu Chen, Le Kuai, Bin Li, Haiqing Dong. Arginine-Nanoenzyme with Timely Angiogenesis for Promoting Diabetic Wound Healing.
ACS applied materials & interfaces.
2024 Feb; 16(8):9640-9655. doi:
10.1021/acsami.3c13072
. [PMID: 38364050] - Liping Qu, Xiao Ma, Feifei Wang. The roles of gut microbiome and metabolites associated with skin photoaging in mice by intestinal flora sequencing and metabolomics.
Life sciences.
2024 Feb; ?(?):122487. doi:
10.1016/j.lfs.2024.122487
. [PMID: 38316265] - José Jesús Gallego-Parrilla, Emmanuele Severi, Govind Chandra, Tracy Palmer. Identification of novel tail-anchored membrane proteins integrated by the bacterial twin-arginine translocase.
Microbiology (Reading, England).
2024 02; 170(2):. doi:
10.1099/mic.0.001431
. [PMID: 38363712] - Xuting Zhang, Wansi Zhong, Rui Xue, Haidi Jin, Xiaoxian Gong, Yuhui Huang, Fujian Chen, Mozi Chen, Liqun Gu, Yebo Ge, Xiaodong Ma, Bifeng Zhong, Mengjie Wang, Haitao Hu, Zhicai Chen, Shenqiang Yan, Yi Chen, Xin Wang, Xiaoling Zhang, Dongjuan Xu, Yuping He, Minfang Lou, Aiju Wang, Xiong Zhang, Li Ma, Xiaodong Lu, Jianer Wang, Qiong Lou, Ping'an Qian, Guomin Xie, Xiaofen Zhu, Songbin He, Jin Hu, Xiongjie Wen, Yan Liu, Yanwen Wang, Jingjing Fu, Weinv Fan, David Liebeskind, Changzheng Yuan, Min Lou. Argatroban in Patients With Acute Ischemic Stroke With Early Neurological Deterioration: A Randomized Clinical Trial.
JAMA neurology.
2024 Feb; 81(2):118-125. doi:
10.1001/jamaneurol.2023.5093
. [PMID: 38190136] - Yufang Guo, Charles S Krasnow, Mary K Hausbeck. Characterizing the Dynamics of Virulence and Fungicide Resistance of Phytophthora capsici in Michigan Vegetable Fields Reveals Loci Associated with Virulence.
Plant disease.
2024 Feb; 108(2):332-341. doi:
10.1094/pdis-03-23-0576-re
. [PMID: 37656035] - Zhi-Fang Lan, Wei Yao, Yi-Ci Xie, Wushisi Chen, Yin-Ying Zhu, Jia-Qi Chen, Xing-Yi Zhou, Jun-Qing Huang, Man-Si Wu, Jia-Xu Chen. Oral Troxerutin Alleviates Depression Symptoms in Mice by Modulating Gut Microbiota and Microbial Metabolism.
Molecular nutrition & food research.
2024 Feb; 68(3):e2300603. doi:
10.1002/mnfr.202300603
. [PMID: 38072646] - Federica Piro, Silvia Masci, Geetha Kannan, Riccardo Focaia, Tracey L Schultz, Pariyamon Thaprawat, Vern B Carruthers, Manlio Di Cristina. A Toxoplasma gondii putative amino acid transporter localizes to the plant-like vacuolar compartment and controls parasite extracellular survival and stage differentiation.
mSphere.
2024 Jan; 9(1):e0059723. doi:
10.1128/msphere.00597-23
. [PMID: 38051073] - Jie Gao, Xiaohua Zhu, Ying Long, Meiling Liu, Haitao Li, Youyu Zhang, Shouzhuo Yao. Boronic Acid-Decorated Carbon Dot-Based Semiselective Multichannel Sensor Array for Cytokine Discrimination and Oral Cancer Diagnosis.
Analytical chemistry.
2024 01; 96(4):1795-1802. doi:
10.1021/acs.analchem.3c05240
. [PMID: 38241199] - Xilin Dai, Xuenan Li, Danhui Yin, Xin Chen, Linwei Wang, Luyao Pang, Yuanshuai Fu. Identification and characterization of TOR in Macrobrachium rosenbergii and its role in muscle protein and lipid production.
Scientific reports.
2024 01; 14(1):2082. doi:
10.1038/s41598-023-50300-3
. [PMID: 38267514] - Xueli Song, Guo Feng, Chenchen Ren, Wei Li, Wen Liu, Gang Liu, Ju Zhang, Yan Lei, Zhengyan He, Caiyao Han, Tingting Liu, Kexin Ma, Jinxin Hou. Study of the mechanism underlying the anti-inflammatory effect of Miao medicine comprising raw and processed Radix Wikstroemia indica using the "sweat soaking method".
Journal of ethnopharmacology.
2024 Jan; 324(?):117770. doi:
10.1016/j.jep.2024.117770
. [PMID: 38219877] - Xiaoli Yang, Chenglin Chi, Wenjing Li, Yanyan Zhang, Shufang Yang, Ruoxuan Xu, Rongxia Liu. Metabolomics and lipidomics combined with serum pharmacochemistry uncover the potential mechanism of Huang-Lian-Jie-Du decoction alleviates atherosclerosis in ApoE-/- mice.
Journal of ethnopharmacology.
2024 Jan; 324(?):117748. doi:
10.1016/j.jep.2024.117748
. [PMID: 38216103] - Wenya Gao, Shuangrong Gao, Yan Zhang, Mengxiao Wang, Yuyang Liu, Tao Li, Chang Gao, Yanyan Zhou, Baolin Bian, Hongjie Wang, Xiaolu Wei, Takashi Sato, Nan Si, Wei Zhao, Haiyu Zhao. Altered metabolic profiles and targets relevant to the protective effect of acteoside on diabetic nephropathy in db/db mice based on metabolomics and network pharmacology studies.
Journal of ethnopharmacology.
2024 Jan; 318(Pt B):117073. doi:
10.1016/j.jep.2023.117073
. [PMID: 37619856] - Shibani Supe, Archana Upadhya, Vikas Dighe, Kavita Singh. Development and Characterization of Modified Chitosan Lipopolyplex for an Effective siRNA Delivery.
AAPS PharmSciTech.
2024 Jan; 25(1):13. doi:
10.1208/s12249-023-02728-z
. [PMID: 38191947] - Fang Cheng, Dan Li, Xijia Ma, Yami Wang, Luyan Lu, Bin Hu, Shuke Cui. Liriodendrin exerts protective effects against chronic endometritis in rats by modulating gut microbiota composition and the arginine/nitric oxide metabolic pathway.
International immunopharmacology.
2024 Jan; 126(?):111235. doi:
10.1016/j.intimp.2023.111235
. [PMID: 38007851] - Yongzhan Zhu, Yinghao Li, Xiaosong Zhou, Haoxuan Li, Min Guo, Peibiao Zhang. Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds.
Journal of materials chemistry. B.
2024 Jan; 12(2):508-524. doi:
10.1039/d3tb01595e
. [PMID: 38108579] - Yuxiang Sun, Tianze Xu, Yike Qian, Qiaoyun Chen, Fei Xiong, Wenxian Du, Li Xu. NOS-like activity of CeO2 nanozymes contributes to diminishing the vascular plaques.
Journal of nanobiotechnology.
2024 Jan; 22(1):12. doi:
10.1186/s12951-023-02276-5
. [PMID: 38166896] - Qiulin Liu, Jiabo Li, Di Han, Jinfeng Wang, Jian Zheng, Wei Ma, Chunqiang Wang. N-carbamylglutamate supplementation induces functional egg production in layers by modulating liver transcriptome profiles.
Poultry science.
2024 Jan; 103(1):103223. doi:
10.1016/j.psj.2023.103223
. [PMID: 38035861] - Peng Li, Guoyao Wu. Characteristics of Nutrition and Metabolism in Dogs and Cats.
Advances in experimental medicine and biology.
2024; 1446(?):55-98. doi:
10.1007/978-3-031-54192-6_4
. [PMID: 38625525] - Haiyan Xie, Ying Chen, Wukun Ge, Xiuping Xu, Chengjiang Liu, Zhiyong Lan, Yina Yang. Can the combination of antiplatelet or alteplase thrombolytic therapy with argatroban benefit patients suffering from acute stroke? a systematic review, meta-analysis, and meta-regression.
PloS one.
2024; 19(2):e0298226. doi:
10.1371/journal.pone.0298226
. [PMID: 38412157] - Biao Pang, Dan Zuo, Tinghai Yang, Junxing Yu, Lizhou Zhou, Yunyan Hou, Jie Yu, Lvlan Ye, Lei Gu, Hongcheng Wang, Xuye Du, Yingliang Liu, Bin Zhu. BcaSOD1 enhances cadmium tolerance in transgenic Arabidopsis by regulating the expression of genes related to heavy metal detoxification and arginine synthesis.
Plant physiology and biochemistry : PPB.
2023 Dec; 206(?):108299. doi:
10.1016/j.plaphy.2023.108299
. [PMID: 38150840] - Samira Saeidi Akbarzadeh, Elaheh Pourfakhraei, Mohsen Zargar, Mona Kashanchi, Seyed Soheil Aghaei. Introducing of high rich lysine, arginine, and unsaturated fatty acids microalga as a food supplement.
World journal of microbiology & biotechnology.
2023 Dec; 40(2):43. doi:
10.1007/s11274-023-03839-2
. [PMID: 38105384] - Denis G Knyazev, Lukas Winter, Andreas Vogt, Sandra Posch, Yavuz Öztürk, Christine Siligan, Nikolaus Goessweiner-Mohr, Nora Hagleitner-Ertugrul, Hans-Georg Koch, Peter Pohl. YidC from Escherichia coli Forms an Ion-Conducting Pore upon Activation by Ribosomes.
Biomolecules.
2023 12; 13(12):. doi:
10.3390/biom13121774
. [PMID: 38136645] - Yiru Wang, Can Wang, Xue Guan, Ying Ma, Shijie Zhang, Fei Li, Yue Yin, Zhenxing Sun, Xiuwei Chen, Hang Yin. PRMT3-Mediated Arginine Methylation of METTL14 Promotes Malignant Progression and Treatment Resistance in Endometrial Carcinoma.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2023 Dec; 10(36):e2303812. doi:
10.1002/advs.202303812
. [PMID: 37973560] - Bateer Baiyin, Yue Xiang, Jiangtao Hu, Kotaro Tagawa, Jung Eek Son, Satoshi Yamada, Qichang Yang. Nutrient Solution Flowing Environment Affects Metabolite Synthesis Inducing Root Thigmomorphogenesis of Lettuce (Lactuca sativa L.) in Hydroponics.
International journal of molecular sciences.
2023 Nov; 24(23):. doi:
10.3390/ijms242316616
. [PMID: 38068940] - Han-Young Kim, Jung-Hoon Kim. Chemical Characterization of the Precipitate Found in and Its Effect on Drug Release of the Scutellaria baicalensis -Coptis chinensis Extract.
Chemistry & biodiversity.
2023 Nov; ?(?):e202301461. doi:
10.1002/cbdv.202301461
. [PMID: 37961037] - Yuki Takechi-Haraya, Takashi Ohgita, Akiko Usui, Kazuchika Nishitsuji, Kenji Uchimura, Yasuhiro Abe, Ryuji Kawano, Monika I Konaklieva, Mart Reimund, Alan T Remaley, Yoji Sato, Ken-Ichi Izutsu, Hiroyuki Saito. Structural flexibility of apolipoprotein E-derived arginine-rich peptides improves their cell penetration capability.
Scientific reports.
2023 11; 13(1):19396. doi:
10.1038/s41598-023-46754-0
. [PMID: 37938626] - Yanan Li, Pingping Dong, Long Dai, Shaoping Wang. Untargeted and Targeted Metabolomics Reveal the Active Peptide of Eupolyphaga sinensis Walker against Hyperlipidemia by Modulating Imbalance in Amino Acid Metabolism.
Molecules (Basel, Switzerland).
2023 Oct; 28(20):. doi:
10.3390/molecules28207049
. [PMID: 37894528] - Junhe Shi, Trevor R Leonardo, Chen Han, Hiba I Bangash, Dandan Chen, Harsh M Trivedi, Lin Chen. L-Arginine Enhances Oral Keratinocyte Proliferation under High-Glucose Conditions via Upregulation of CYP1A1, SKP2, and SRSF5.
Molecules (Basel, Switzerland).
2023 Oct; 28(20):. doi:
10.3390/molecules28207020
. [PMID: 37894498] - Diego Freitas de Araujo, Bianca Feitosa Holanda, Francisco Lucas Faustino do Nascimento, Alice Brito Martins, Alefe Lopes Macario Silva, Maria Gonçalves Pereira, Alana de Freitas Pires, Ana Maria Sampaio Assreuy. Polysaccharide-rich extract of Genipa americana leaves exerts anti-inflammatory effects modulated by platelet mediators.
Journal of ethnopharmacology.
2023 Oct; 319(Pt 2):117234. doi:
10.1016/j.jep.2023.117234
. [PMID: 37793578] - Chi Chen, Zhijuan Hu, Xinyao Zheng, Jingjie Yuan, Run Zou, Yilan Wang, Xuan Peng, Chengjian Xie. The essential role of arginine biosynthetic genes in lunate conidia formation, conidiation, mycelial growth, and virulence of nematophagous fungus, Esteya vermicola CBS115803.
Pest management science.
2023 Oct; ?(?):. doi:
10.1002/ps.7809
. [PMID: 37781870] - S Kwiecień, D Wojcik-Grzybek, Z Sliwowski, A Targosz, A Chmura, K Magierowska, M Strzalka, U Glowacka, A Ptak-Belowska, M Magierowski, T Brzozowski. Inhibition of endogenous nitric oxide activity impairs the colonic sparing effect of rofecoxib, the cyclooxygenase-2 inhibitor and resveratrol, the preferential cyclooxygenase-1 inhibitor in the course of experimental colitis. Role of oxidative stress biomarkers and proinflammatory cytokines.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2023 Oct; 74(5):. doi:
10.26402/jpp.2023.5.08
. [PMID: 38085520] - Qiang Guo, Xiaoyan Chen, Bo Li. Purification and characterization of tomato arginine decarboxylase and its inhibition by the bacterial small molecule phevamine A.
Protein expression and purification.
2023 10; 210(?):106326. doi:
10.1016/j.pep.2023.106326
. [PMID: 37348664] - Amina M Haroun, Wael M El-Sayed, Rasha E Hassan. Quercetin and L-Arginine Ameliorated the Deleterious Effects of Copper Oxide Nanoparticles on the Liver of Mice Through Anti-inflammatory and Anti-apoptotic Pathways.
Biological trace element research.
2023 Sep; ?(?):. doi:
10.1007/s12011-023-03884-w
. [PMID: 37775700] - Lifeng Zhang, Jiali Yang, Wencong Liu, Qiteng Ding, Shuwen Sun, Shuai Zhang, Ning Wang, Yue Wang, Siyu Xi, Chunyu Liu, Chuanbo Ding, Changtian Li. A phellinus igniarius polysaccharide/chitosan-arginine hydrogel for promoting diabetic wound healing.
International journal of biological macromolecules.
2023 Sep; 249(?):126014. doi:
10.1016/j.ijbiomac.2023.126014
. [PMID: 37517765] - Dirk Mossmann, Christoph Müller, Sujin Park, Brendan Ryback, Marco Colombi, Nathalie Ritter, Diana Weißenberger, Eva Dazert, Mairene Coto-Llerena, Sandro Nuciforo, Lauriane Blukacz, Caner Ercan, Veronica Jimenez, Salvatore Piscuoglio, Fatima Bosch, Luigi M Terracciano, Uwe Sauer, Markus H Heim, Michael N Hall. Arginine reprograms metabolism in liver cancer via RBM39.
Cell.
2023 Sep; ?(?):. doi:
10.1016/j.cell.2023.09.011
. [PMID: 37804830] - Siyu Chen, Zhongliang Chen, Xinru Lin, Xinyan Zhou, Shangdong Yang, Hongwei Tan. Why different sugarcane cultivars show different resistant abilities to smut? : Comparisons of endophytic microbial compositions and metabolic functions in stems of sugarcane cultivars with different abilities to resist smut.
BMC plant biology.
2023 Sep; 23(1):427. doi:
10.1186/s12870-023-04446-x
. [PMID: 37710150] - Zhaohu Hao, Junxin Yao, Xiaoying Zhao, Ran Liu, Baocheng Chang, Hailin Shao. Preliminary observational study of metabonomics in patients with early and late-onset type 2 diabetes mellitus based on UPLC-Q-TOF/MS.
Scientific reports.
2023 09; 13(1):14579. doi:
10.1038/s41598-023-41883-y
. [PMID: 37666906] - Xinwei Xu, Dickson Kofi Wiredu Ocansey, Bing Pei, Yaqin Zhang, Naijian Wang, Zengxu Wang, Fei Mao. Resveratrol alleviates DSS-induced IBD in mice by regulating the intestinal microbiota-macrophage-arginine metabolism axis.
European journal of medical research.
2023 Sep; 28(1):319. doi:
10.1186/s40001-023-01257-6
. [PMID: 37660064] - M Elisa Fait, Patricia D Grillo, Graciela L Garrote, Eduardo D Prieto, Romina F Vázquez, Mario C N Saparrat, Susana R Morcelle. Biocidal and antibiofilm activities of arginine-based surfactants against Candida isolates.
Amino acids.
2023 Sep; 55(9):1083-1102. doi:
10.1007/s00726-023-03296-z
. [PMID: 37382761] - Lu Zhang, Guangjun Jiao, Yunhao You, Xiang Li, Jincheng Liu, Zhenqian Sun, Qinghui Li, Zihan Dai, Jinlong Ma, Hongming Zhou, Gang Li, Chunyang Meng, Yunzhen Chen. Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation.
Clinical and translational medicine.
2023 09; 13(9):e1369. doi:
10.1002/ctm2.1369
. [PMID: 37649137] - Jiaqi Wang, Yajuan Wang, Yuxuan Li, Ling Yang, Bingxin Sun, Yunhe Zhang, Yufeng Xu, Xuerui Yan. l-Arginine treatment maintains postharvest quality in blueberry fruit by enhancing antioxidant capacity during storage.
Journal of food science.
2023 Sep; 88(9):3666-3680. doi:
10.1111/1750-3841.16710
. [PMID: 37477270] - Yuanming Xie, Yuanda Lv, Letian Jia, Lulu Zheng, Yonghui Li, Ming Zhu, Mengjun Tian, Ming Wang, Weicong Qi, Long Luo, Hugues De Gernier, Pierre-Mathieu Pélissier, Hans Motte, Shaoyan Lin, Le Luo, Guohua Xu, Tom Beeckman, Wei Xuan. Plastid-localized amino acid metabolism coordinates rice ammonium tolerance and nitrogen use efficiency.
Nature plants.
2023 Aug; ?(?):. doi:
10.1038/s41477-023-01494-x
. [PMID: 37604972] - Sungyun Cho, Yujin Chun, Long He, Cuauhtemoc B Ramirez, Kripa S Ganesh, Kyungjo Jeong, Junho Song, Jin Gyu Cheong, Zhongchi Li, Jungmin Choi, Joohwan Kim, Nikos Koundouros, Fangyuan Ding, Noah Dephoure, Cholsoon Jang, John Blenis, Gina Lee. FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1.
Molecular cell.
2023 Aug; 83(16):3010-3026.e8. doi:
10.1016/j.molcel.2023.07.017
. [PMID: 37595559] - Qianqian Chen, Jinhe Zhang, Mutu Huang, Peiqi Wang, Xiao Zhang, Mingjun Ma. Construction of 131I-RGDyC-PEG-PAMAM-DTX targeted drug delivery system and study of its physicochemical properties and biological activity.
Hellenic journal of nuclear medicine.
2023 Aug; ?(?):. doi:
10.1967/s002449912574
. [PMID: 37527047] - Kaili Zhu, Changcheng Zhang, Xiaoping Wu, Shangyu Liu, Xueyi Zhao, Ding Yuan, Haixia Zhao. [The mechanism of microcystin leucine-arginine (MC-LR)-induced injury of Sertoli cell immune response and biological behavior].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2023 Aug; 39(8):753-758. doi:
. [PMID: 37515343]
- Guadalupe Medina-de la Rosa, Felipe García-Oliva, Cesaré Ovando-Vázquez, Lourdes B Celis-García, Lucía López-Reyes, Nguyen Esmeralda López-Lozano. Amino Acids in the Root Exudates of Agave lechuguilla Torr. Favor the Recruitment and Enzymatic Activity of Nutrient-Improvement Rhizobacteria.
Microbial ecology.
2023 Aug; 86(2):1176-1188. doi:
10.1007/s00248-022-02162-x
. [PMID: 36571608] - Nadine Soudah, Alexey Baskin, Karin Smorodinsky-Atias, Jonah Beenstock, Yifat Ganon, Ruchama Hayouka, Mohammed Aboraya, Oded Livnah, Ronit Ilouz, David Engelberg. A conserved arginine within the αC-helix of Erk1/2 is a latch of autoactivation and of oncogenic capabilities.
The Journal of biological chemistry.
2023 Jul; ?(?):105072. doi:
10.1016/j.jbc.2023.105072
. [PMID: 37474104] - Shuai Zhao, Li-Xiang Mo, Wen-Tong Li, Lian-Li Jiang, Yi-Yuan Meng, Jian-Feng Ou, Lu-Sheng Liao, Yu-Si Yan, Xue-Mei Luo, Jia-Xun Feng. Arginine methyltransferases PRMT2 and PRMT3 are essential for biosynthesis of plant-polysaccharide-degrading enzymes in Penicillium oxalicum.
PLoS genetics.
2023 07; 19(7):e1010867. doi:
10.1371/journal.pgen.1010867
. [PMID: 37523410] - Kun Ho Kim, Zhihao Jia, Madigan Snyder, Jingjuan Chen, Jiamin Qiu, Stephanie N Oprescu, Xiyue Chen, Sabriya A Syed, Feng Yue, Bruno T Roseguini, Anthony N Imbalzano, Changdeng Hu, Shihuan Kuang. PRMT5 links lipid metabolism to contractile function of skeletal muscles.
EMBO reports.
2023 Jun; ?(?):e57306. doi:
10.15252/embr.202357306
. [PMID: 37334900] - Mohammad Amin Behmanesh, Amin Rasekhian, Forutan Kiani, Mostafa Dehghandoost, Davood Alinezhad Dezfuli, Behnam Ghorbanzadeh. The nitric oxide-cyclic GMP-KATP channels pathway contributes to the effects of montelukast against gastric damage induced by ethanol.
Alcohol (Fayetteville, N.Y.).
2023 Jun; ?(?):. doi:
10.1016/j.alcohol.2023.05.008
. [PMID: 37295565] - Qianyi Wang, Yue Guo, Shisui Feng, Mingwei Meng, Zheng Huang, Jinghua Qin, Bingjian Guo, Chi Zhang, Yunyuan Nong, Linlin Feng, Hui Song, Yonghong Liang, Zhiheng Su. Metabolomics and molecular docking analysis of antibiotic exposure in Bifidobacterium adolescentis.
Letters in applied microbiology.
2023 Jun; 76(6):. doi:
10.1093/lambio/ovad061
. [PMID: 37204035] - Tianxiao Zhou, Kaige Yang, Yinjie Ma, Jin Huang, Wenchang Fu, Chao Yan, Xinyan Li, Yan Wang. GC/MS-Based Analysis of Fatty Acids and Amino Acids in H460 Cells Treated with Short-Chain and Polyunsaturated Fatty Acids: A Highly Sensitive Approach.
Nutrients.
2023 May; 15(10):. doi:
10.3390/nu15102342
. [PMID: 37242225] - Zi-Chang Jia, Debatosh Das, Youjun Zhang, Alisdair R Fernie, Ying-Gao Liu, Moxian Chen, Jianhua Zhang. Plant serine/arginine-rich proteins: versatile players in RNA processing.
Planta.
2023 May; 257(6):109. doi:
10.1007/s00425-023-04132-0
. [PMID: 37145304] - Lindsey O Calabretta, Jinyi Yang, Ronald T Raines. Nα -Methylation of arginine: Implications for cell-penetrating peptides.
Journal of peptide science : an official publication of the European Peptide Society.
2023 May; 29(5):e3468. doi:
10.1002/psc.3468
. [PMID: 36494904] - Yutan Shen, Hongrui Lin, Ming Yang, Xuefeng Gong, Bo Guan, Yuchun Han, Shu Wang, Yilin Wang. Hierarchical Superstructure of Plant Polyphenol and Arginine Surfactant for Long-Lasting and Target-Selective Antimicrobial Application.
Advanced materials (Deerfield Beach, Fla.).
2023 May; 35(19):e2210936. doi:
10.1002/adma.202210936
. [PMID: 36810927] - Jun-Yi Li, Yan-Chao Guo, Hai-Feng Zhou, Tian-Tian Yue, Fa-Xi Wang, Fei Sun, Wen-Zhu Wang. Arginine metabolism regulates the pathogenesis of inflammatory bowel disease.
Nutrition reviews.
2023 04; 81(5):578-586. doi:
10.1093/nutrit/nuac070
. [PMID: 36040377] - Laura Dowsett, Lucie Duluc, Erin Higgins, Fatmah Alghamdi, Walter Fast, Ian P Salt, James Leiper. Asymmetric dimethylarginine positively modulates calcium-sensing receptor signalling to promote lipid accumulation.
Cellular signalling.
2023 Apr; ?(?):110676. doi:
10.1016/j.cellsig.2023.110676
. [PMID: 37028778] - Lea Pašalić, Barbara Pem, Darija Domazet Jurašin, Mario Vazdar, Danijela Bakarić. Interaction of guanidinium and ammonium cations with phosphatidylcholine and phosphatidylserine lipid bilayers - Calorimetric, spectroscopic and molecular dynamics simulations study.
Biochimica et biophysica acta. Biomembranes.
2023 04; 1865(4):184122. doi:
10.1016/j.bbamem.2023.184122
. [PMID: 36739930] - Milad Rahemi, Shokooh Mohtadi, Hossein Rajabi Vardanjani, Mohammad Javad Khodayar. The role of L-arginine/NO/cGMP/KATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test.
Behavioural pharmacology.
2023 Mar; ?(?):. doi:
10.1097/fbp.0000000000000721
. [PMID: 36939560] - Shuang Chao, Ziyan Shen, Bowen Li, Yuxin Pei, Zhichao Pei. An L-arginine-functionalized pillar[5]arene-based supramolecular photosensitizer for synergistically enhanced cancer therapeutic effectiveness.
Chemical communications (Cambridge, England).
2023 Mar; 59(23):3455-3458. doi:
10.1039/d3cc00123g
. [PMID: 36866731] - Zhuoran Yang, Chunyu Yang, Dan Yang, Ye Zhang, Qingzhu Yang, Fengyu Qu, Wei Guo. l-Arginine-Modified CoWO4 /FeWO4 S-Scheme Heterojunction Enhances Ferroptosis against Solid Tumor.
Advanced healthcare materials.
2023 Mar; ?(?):e2203092. doi:
10.1002/adhm.202203092
. [PMID: 36907173] - Mikayel Ginovyan, Hayarpi Javrushyan, Gayane Petrosyan, Barbara Kusznierewicz, Izabela Koss-Mikołajczyk, Zuzanna Koziara, Monika Kuczyńska, Patrycja Jakubek, Anna Karapetyan, Naira Sahakyan, Alina Maloyan, Agnieszka Bartoszek, Nikolay Avtandilyan. Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis.
The international journal of biochemistry & cell biology.
2023 Mar; 158(?):106396. doi:
10.1016/j.biocel.2023.106396
. [PMID: 36918141] - Yao Zheng, Cécile Cabassa-Hourton, Séverine Planchais, Emilie Crilat, Gilles Clément, Matthieu Dacher, Nina Durand, Marianne Bordenave-Jacquemin, Anne Guivarc'h, Corentin Dourmap, Pierre Carol, Sandrine Lebreton, Arnould Savouré. Pyrroline-5-carboxylate dehydrogenase is an essential enzyme for proline dehydrogenase function during dark-induced senescence in Arabidopsis thaliana.
Plant, cell & environment.
2023 03; 46(3):901-917. doi:
10.1111/pce.14529
. [PMID: 36583533] - Dan Parkin, Mitsunori Takano. Coulombic Organization in Membrane-Embedded Rotary Motor of ATP Synthase.
The journal of physical chemistry. B.
2023 02; 127(7):1552-1562. doi:
10.1021/acs.jpcb.2c07875
. [PMID: 36734508] - Pilar Rodríguez-Rodríguez, Anuson Poasakate, Santiago Ruvira-Hernando, Perla Y Gutierrez-Arzapalo, Rainer Böger, Juliane Hannemann, Nicole Lüneburg, Silvia M Arribas. Vascular nitrosative stress in hypertension induced by fetal undernutrition in rats.
Journal of physiology and biochemistry.
2023 Feb; ?(?):. doi:
10.1007/s13105-023-00949-1
. [PMID: 36821073] - Yang Liu, Andrew J Wilson, Jiatong Han, Alisa Hui, Lucy O'Sullivan, Tao Huan, Cara H Haney. Amino Acid Availability Determines Plant Immune Homeostasis in the Rhizosphere Microbiome.
mBio.
2023 Feb; ?(?):e0342422. doi:
10.1128/mbio.03424-22
. [PMID: 36786577] - Shan Yang, Na Chu, Naijie Feng, Bolin Zhou, Hongkai Zhou, Zuhu Deng, Xuefeng Shen, Dianfeng Zheng. Global Responses of Autopolyploid Sugarcane Badila (Saccharum officinarum L.) to Drought Stress Based on Comparative Transcriptome and Metabolome Profiling.
International journal of molecular sciences.
2023 Feb; 24(4):. doi:
10.3390/ijms24043856
. [PMID: 36835268] - Fengyang Li, Xiuhong Hu, Zengshuai Wu, Qiulei Yang, Qila Sa, Wenbo Ren, Tingting Wang, Zhengchao Ji, Na Li, Jing Huang, Liancheng Lei. Untargeted metabolomics reveals alternations in metabolism of bovine mammary epithelial cells upon IFN-γ treatment.
BMC veterinary research.
2023 Feb; 19(1):44. doi:
10.1186/s12917-023-03588-2
. [PMID: 36765367] - Fahrul Nurkolis, Nurpudji Astuti Taslim, Dionysius Subali, Rudy Kurniawan, Hardinsyah Hardinsyah, William Ben Gunawan, Rio Jati Kusuma, Vincentius Mario Yusuf, Adriyan Pramono, Sojin Kang, Nelly Mayulu, Andi Yasmin Syauki, Trina Ekawati Tallei, Apollinaire Tsopmo, Bonglee Kim. Dietary Supplementation of Caulerpa racemosa Ameliorates Cardiometabolic Syndrome via Regulation of PRMT-1/DDAH/ADMA Pathway and Gut Microbiome in Mice.
Nutrients.
2023 Feb; 15(4):. doi:
10.3390/nu15040909
. [PMID: 36839268] - Melisa Hermet, Yanis Ricardo Espinosa, María Elisa Fait, Yenisleidy de Las M Zulueta Díaz, Susana Morcelle, Laura S Bakás, H Ariel Ariel Alvarez, María Laura Fanani. Arginine-based surfactants alter the rheological and in-plane structural properties of stratum corneum model membranes.
Journal of colloid and interface science.
2023 Feb; 631(Pt B):224-238. doi:
10.1016/j.jcis.2022.10.118
. [PMID: 36401930] - Ruba H Ghanam, Gunnar N Eastep, Jamil S Saad. Structural Insights into the Mechanism of HIV-1 Tat Secretion from the Plasma Membrane.
Journal of molecular biology.
2023 01; 435(2):167880. doi:
10.1016/j.jmb.2022.167880
. [PMID: 36370804] - Yaohua Cheng, Qiuyan Ban, Junlin Mao, Mengling Lin, Xiangxiang Zhu, Yuhui Xia, Xiaojie Cao, Xianchen Zhang, Yeyun Li. Integrated Metabolomic and Transcriptomic Analysis Reveals That Amino Acid Biosynthesis May Determine Differences in Cold-Tolerant and Cold-Sensitive Tea Cultivars.
International journal of molecular sciences.
2023 Jan; 24(3):. doi:
10.3390/ijms24031907
. [PMID: 36768228] - Junichi Fujii, Tsukasa Osaki. Involvement of Nitric Oxide in Protecting against Radical Species and Autoregulation of M1-Polarized Macrophages through Metabolic Remodeling.
Molecules (Basel, Switzerland).
2023 Jan; 28(2):. doi:
10.3390/molecules28020814
. [PMID: 36677873] - Puqiao Lian, Paul A J Henricks, Harry J Wichers, Gert Folkerts, Saskia Braber. Differential Effects of Oligosaccharides, Antioxidants, Amino Acids and PUFAs on Heat/Hypoxia-Induced Epithelial Injury in a Caco-2/HT-29 Co-Culture Model.
International journal of molecular sciences.
2023 Jan; 24(2):. doi:
10.3390/ijms24021111
. [PMID: 36674626] - Arne Matteo Jörgensen, Patrick Knoll, Soheil Haddadzadegan, Hannah Fabian, Andrea Hupfauf, Ronald Gust, Rainer Georg Jörgensen, Andreas Bernkop-Schnürch. Biodegradable arginine based steroid-surfactants: Cationic green agents for hydrophobic ion-pairing.
International journal of pharmaceutics.
2023 Jan; 630(?):122438. doi:
10.1016/j.ijpharm.2022.122438
. [PMID: 36464112] - Biao Jiang, Changmei Long, Yu Xu, Lizhen Han. Molecular mechanism of Tsukamurella tyrosinosolvens strain P9 in response to root exudates of peanut.
Archives of microbiology.
2023 Jan; 205(1):48. doi:
10.1007/s00203-022-03387-7
. [PMID: 36595098] - Jian Zhang, Jianlong Yuan, Juncheng Lin, Lixian Chen, Li-Yuan You, Shuling Chen, Li Peng, Chun-Han Wang, Jiamu Du, Cheng-Guo Duan. Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants.
Proceedings of the National Academy of Sciences of the United States of America.
2023 01; 120(1):e2208525120. doi:
10.1073/pnas.2211155120
. [PMID: 36580600]