2-Hydroxyxanthone (BioDeep_00000021603)

human metabolite

代谢物信息卡片

2-Hydroxy-9H-xanthen-9-one, 9ci

化学式: C13H8O3 (212.0473418)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(=O)c2c(oc3c1cc(cc3)O)cccc2
InChI: InChI=1S/C13H8O3/c14-8-5-6-12-10(7-8)13(15)9-3-1-2-4-11(9)16-12/h1-7,14H

描述信息

2-Hydroxyxanthone belongs to the class of organic compounds known as xanthones. These are polycyclic aromatic compounds containing a xanthene moiety conjugated to a ketone group at carbon 9. Xanthene is a tricyclic compound made up of two benzene rings linearly fused to each other through a pyran ring. 2-Hydroxyxanthone exists as a solid and is considered to be practically insoluble (in water) and relatively neutral. Within the cell, 2-hydroxyxanthone is primarily located in the membrane (predicted from logP). Outside of the human body, 2-hydroxyxanthone can be found in fruits, herbs and spices, and mammee apple. This makes 2-hydroxyxanthone a potential biomarker for the consumption of these food products.
Constituent of Hypericum subspecies, Mammea americana (mamey). 2-Hydroxyxanthone is found in herbs and spices, fruits, and mammee apple.

同义名列表

5 个代谢物同义名

2-Hydroxy-9H-xanthen-9-one, 9ci; 2-Hydroxy-9H-xanthen-9-one; 2-Hydroxy-xanthen-9-one; 2-hydroxyxanthen-9-one; 2-Hydroxyxanthone

数据库引用编号

9 个数据库交叉引用编号

ChEBI: CHEBI:108579
PubChem: 74708
HMDB: HMDB0032997
ChEMBL: CHEMBL185960
KNApSAcK: C00035014
foodb: FDB010986
chemspider: 67281
CAS: 1915-98-6
PMhub: MS000067089

分类词条

Xanthones

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

35 个相关的物种来源信息

282553 Hypericum sampsonii:
271747 Mammea odorata: 10.1016/S0031-9422(00)97372-2
999598 Vismia guianensis: 10.1016/S0031-9422(00)80095-3
282542 Hypericum japonicum: 10.1016/J.PHYTOCHEM.2006.05.043
684760 Hypericum monogynum: 10.1016/J.PHYTOCHEM.2006.05.043
1692142 Hypericum chinense: 10.1016/J.PHYTOCHEM.2006.05.043
673938 Hypericum inodorum: 10.3987/COM-91-5909
198777 Mammea americana:
1009336 Calophyllum membranaceum:
667334 Calophyllum teysmannii:
2508373 Kielmeyera excelsa:
2508385 Kielmeyera speciosa: 10.1016/S0031-9422(00)85774-X
2662340 Mesua assamica:
268990 Hypericum ericoides:
469930 Garcinia kola: 10.1080/10575639908041215
228412 Hypericum canariense:
269018 Hypericum roeperianum: 10.1016/0031-9422(96)00284-1
282553 Hypericum sampsonii:
271747 Mammea odorata: 10.1016/S0031-9422(00)97372-2
999598 Vismia guianensis: 10.1016/S0031-9422(00)80095-3
282542 Hypericum japonicum: 10.1016/J.PHYTOCHEM.2006.05.043
684760 Hypericum monogynum: 10.1016/J.PHYTOCHEM.2006.05.043
1692142 Hypericum chinense: 10.1016/J.PHYTOCHEM.2006.05.043
673938 Hypericum inodorum: 10.3987/COM-91-5909
198777 Mammea americana:
1009336 Calophyllum membranaceum:
667334 Calophyllum teysmannii:
2508373 Kielmeyera excelsa:
2508385 Kielmeyera speciosa: 10.1016/S0031-9422(00)85774-X
2662340 Mesua assamica:
268990 Hypericum ericoides:
469930 Garcinia kola: 10.1080/10575639908041215
228412 Hypericum canariense:
269018 Hypericum roeperianum: 10.1016/0031-9422(96)00284-1
9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Ralph Urbatzka, Sara Freitas, Andreia Palmeira, Tiago Almeida, João Moreira, Carlos Azevedo, Carlos Afonso, Marta Correia-da-Silva, Emilia Sousa, Madalena Pinto, Vitor Vasconcelos. Lipid reducing activity and toxicity profiles of a library of polyphenol derivatives. European journal of medicinal chemistry. 2018 May; 151(?):272-284. doi: 10.1016/j.ejmech.2018.03.036. [PMID: 29626799]
Yan-zhi Li, Zhan-lin Li, Hui-ming Hua, Zheng-gang Li, Ming-sheng Liu. [Studies on flavonoids from stems and leaves of Calophyllum inophyllum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Apr; 32(8):692-4. doi: . [PMID: 17608221]
Gérald Larcher, Cécile Morel, Guy Tronchin, Anne Landreau, Denis Séraphin, Pascal Richomme, Jean-Philippe Bouchara. Investigation of the antifungal activity of caledonixanthone E and other xanthones against Aspergillus fumigatus. Planta medica. 2004 Jun; 70(6):569-71. doi: 10.1055/s-2004-827161. [PMID: 15229808]