Acetonitrile (BioDeep_00000020712)
human metabolite
代谢物信息卡片
Acetonitrile, 1-(14)C-labeled
化学式: C2H3N (41.026547799999996)
中文名称: 乙腈
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC#N
InChI: InChI=1S/C2H3N/c1-2-3/h1H3
描述信息
Acetonitrile is the chemical compound with the formula CH3CN. This colourless liquid is the simplest organic nitrile . It is produced mainly as a byproduct of acrylonitrile manufacture. It is used as a polar aprotic solvent in organic synthesis and in the purification of butadiene.
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:38472
- PubChem: 6342
- HMDB: HMDB0061869
- ChEMBL: CHEMBL45211
- Wikipedia: Acetonitrile
- CAS: 148642-19-7
- CAS: 75-05-8
- PMhub: MS000048809
- RefMet: Acetonitrile
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fatima Maqoud, Antonella Orlando, Domenico Tricarico, Marina Antonacci, Annamaria Di Turi, Gianluigi Giannelli, Francesco Russo. Anti-Inflammatory Effects of a Novel Acetonitrile-Water Extract of Lens Culinaris against LPS-Induced Damage in Caco-2 Cells.
International journal of molecular sciences.
2024 Mar; 25(7):. doi:
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2022 Dec; 40(12):1076-1086. doi:
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Chemosphere.
2022 Dec; 309(Pt 1):136725. doi:
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Molecules (Basel, Switzerland).
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Molecules (Basel, Switzerland).
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The Journal of pharmacy and pharmacology.
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Chemosphere.
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Journal of separation science.
2019 Feb; 42(4):871-877. doi:
10.1002/jssc.201801012. [PMID: 30580477] - Norihiro Sakurai, Yasutaka Nakamura, Hiroshi Kawaguchi, Junko Abe, Koichi Yamada, Katsuya Nagayama, Hiroshi Kakeya. Measurement of Linezolid and Its Metabolites PNU-142300 and PNU-142586 in Human Plasma Using Ultra-Performance Liquid Chromatography Method.
Chemical & pharmaceutical bulletin.
2019; 67(5):439-444. doi:
10.1248/cpb.c18-00840. [PMID: 31061368] - Omar S Ahmed, Yoann Ladner, Jérôme Montels, Laurent Philibert, Catherine Perrin. Coupling of salting-out assisted liquid-liquid extraction with on-line stacking for the analysis of tyrosine kinase inhibitors in human plasma by capillary zone electrophoresis.
Journal of chromatography. A.
2018 Dec; 1579(?):121-128. doi:
10.1016/j.chroma.2018.10.017. [PMID: 30361035] - Tianyu Ma, Hongjing Dong, Heng Lu, Hengqiang Zhao, Lanping Guo, Xiao Wang. Preparative separation of caffeoylquinic acid isomers from Lonicerae japonicae Flos by pH-zone-refining counter-current chromatography and a strategy for selection of solvent systems with high sample loading capacities.
Journal of chromatography. A.
2018 Nov; 1578(?):61-66. doi:
10.1016/j.chroma.2018.10.014. [PMID: 30366692] - Jonathan R Moulins, Michel Blais, Kim Montsion, Josee Tully, William Mohan, Mathieu Gagnon, Tyler McRitchie, Keri Kwong, Neil Snider, David R Blais. Multiresidue Method of Analysis of Pesticides in Medical Cannabis.
Journal of AOAC International.
2018 Nov; 101(6):1948-1960. doi:
10.5740/jaoacint.17-0495. [PMID: 29843862] - Revathy Sankaran, Sivakumar Manickam, Yee Jiun Yap, Tau Chuan Ling, Jo-Shu Chang, Pau Loke Show. Extraction of proteins from microalgae using integrated method of sugaring-out assisted liquid biphasic flotation (LBF) and ultrasound.
Ultrasonics sonochemistry.
2018 Nov; 48(?):231-239. doi:
10.1016/j.ultsonch.2018.06.002. [PMID: 30080546] - Carsten Müller, Cornelia Fietz, Philipp Koehler, Graham Sibley, Achu Che Awah Nforbugwe, Thomas Streichert, Martin H J Wiesen. Reliable and Easy-To-Use Liquid Chromatography-Tandem Mass Spectrometry Assay for Quantification of Olorofim (F901318), a Novel Antifungal Drug, in Human Plasma and Serum.
Antimicrobial agents and chemotherapy.
2018 11; 62(11):. doi:
10.1128/aac.01356-18. [PMID: 30150474] - Petr Tůma, Miroslava Bursová, Blanka Sommerová, Rachel Horsley, Radomír Čabala, Tomáš Hložek. Novel electrophoretic acetonitrile-based stacking for sensitive monitoring of the antiepileptic drug perampanel in human serum.
Journal of pharmaceutical and biomedical analysis.
2018 Oct; 160(?):368-373. doi:
10.1016/j.jpba.2018.08.006. [PMID: 30121554] - Xianduo Sun, Xiaomin Tang, Quan Yang. An effective quantitative fingerprint method for evaluating the quality consistency of Desmodium styracifolium.
Die Pharmazie.
2018 10; 73(10):579-584. doi:
10.1691/ph.2018.8590. [PMID: 30223921] - Cunying Huang, Huihui Wan, Jing Zhang, Hongmin Zhong, Juan Li, YuMing Sun, Qing Wang, Hua Zhang. Quantification of ondansetron, granisetron and tropisetron in goat plasma using hydrophilic interaction liquid chromatography-solid phase extraction coupled with hydrophilic interaction liquid chromatography-triple quadrupole tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Sep; 1095(?):50-58. doi:
10.1016/j.jchromb.2018.07.009. [PMID: 30053687] - Liang Liu, Shuang Hu, Suodi Zhai, Xin Hai. Analysis of monofluoroacetic acid in human plasma by UFLC-MS/MS and its application in patients with sodium monofluoroacetate or monofluoroacetamide poisoning.
Journal of pharmaceutical and biomedical analysis.
2018 Sep; 158(?):370-375. doi:
10.1016/j.jpba.2018.06.028. [PMID: 29936376] - Katerina Grabicova, Andrea Vojs Staňová, Olga Koba Ucun, Adam Borik, Tomas Randak, Roman Grabic. Development of a robust extraction procedure for the HPLC-ESI-HRPS determination of multi-residual pharmaceuticals in biota samples.
Analytica chimica acta.
2018 Aug; 1022(?):53-60. doi:
10.1016/j.aca.2018.04.011. [PMID: 29729738] - David Moreno-González, Jaime Alcántara-Durán, Silvina M Addona, Miriam Beneito-Cambra. Multi-residue pesticide analysis in virgin olive oil by nanoflow liquid chromatography high resolution mass spectrometry.
Journal of chromatography. A.
2018 Aug; 1562(?):27-35. doi:
10.1016/j.chroma.2018.05.053. [PMID: 29861303] - Ali Nazaripour, Yadollah Yamini, Hasan Bagheri. Extraction and determination of trace amounts of three anticancer pharmaceuticals in urine by three-phase hollow fiber liquid-phase microextraction based on two immiscible organic solvents followed by high-performance liquid chromatography.
Journal of separation science.
2018 Aug; 41(15):3113-3120. doi:
10.1002/jssc.201800183. [PMID: 29869408] - Tsutomu Arakawa. Acetonitrile as solvent for protein interaction analysis.
International journal of biological macromolecules.
2018 Jul; 114(?):728-732. doi:
10.1016/j.ijbiomac.2018.03.174. [PMID: 29605253] - Udani L Kathriarachchi, Sagar S Vidhate, Naser Al-Tannak, Alison H Thomson, Michael J J da Silva Neto, David G Watson. Development of a LC-MS method for simultaneous determination of amoxicillin and metronidazole in human serum using hydrophilic interaction chromatography (HILIC).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Jul; 1089(?):78-83. doi:
10.1016/j.jchromb.2018.05.012. [PMID: 29775840] - Denglang Zou, Yurong Du, Jianyuan Kuang, Shihao Sun, Jianbin Ma, Renwang Jiang. PH-zone-refining counter-current chromatography with a hydrophilic organic/salt-containing two-phase solvent system for preparative separation of polar alkaloids from natural products.
Journal of chromatography. A.
2018 Jun; 1553(?):1-6. doi:
10.1016/j.chroma.2018.04.007. [PMID: 29680742] - Zeynep Kalaycıoğlu, Sesil Uzaşçı, Tuncay Dirmenci, F Bedia Erim. α-Glucosidase enzyme inhibitory effects and ursolic and oleanolic acid contents of fourteen Anatolian Salvia species.
Journal of pharmaceutical and biomedical analysis.
2018 Jun; 155(?):284-287. doi:
10.1016/j.jpba.2018.04.014. [PMID: 29677678] - Xiaowen Guan, Donna Ruszaj, Marilyn E Morris. Development and validation of a liquid chromatography tandem mass spectrometry assay for AZD3965 in mouse plasma and tumor tissue: Application to pharmacokinetic and breast tumor xenograft studies.
Journal of pharmaceutical and biomedical analysis.
2018 Jun; 155(?):270-275. doi:
10.1016/j.jpba.2018.03.061. [PMID: 29674138] - Gulin Amasya, Mehmet Gumustas, Ulya Badilli, Sibel A Ozkan, Nilufer Tarimci. Development of a HILIC method for the determination of 5-fluorouracil from nano drug delivery systems and rat skin extracts.
Journal of pharmaceutical and biomedical analysis.
2018 May; 154(?):285-293. doi:
10.1016/j.jpba.2018.03.021. [PMID: 29567571] - Ji Ye, Yanxia Gao, Saisai Tian, Juan Su, Weidong Zhang. A novel and effective mode-switching triple quadrupole mass spectrometric approach for simultaneous quantification of fifteen ginsenosides in Panax ginseng.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2018 May; 44(?):164-172. doi:
10.1016/j.phymed.2018.02.007. [PMID: 29548720] - Hai Jiang, Liu Yang, Xudong Xing, Meiling Yan, Xinyue Guo, Bingyou Yang, Qiu-Hong Wang, Hai-Xue Kuang. Development of an analytical method for separation of phenolic acids by ultra-performance convergence chromatography (UPC2) using a column packed with a sub-2-μm particle.
Journal of pharmaceutical and biomedical analysis.
2018 May; 153(?):117-125. doi:
10.1016/j.jpba.2018.02.027. [PMID: 29477129] - Sandeep R Kunati, Shuming Yang, David Wald, Yan Xu. Development and validation of an LC-MS/MS method for quantitative determination of GS87, a novel antineoplastic agent, in mouse plasma.
Journal of pharmaceutical and biomedical analysis.
2018 May; 153(?):145-151. doi:
10.1016/j.jpba.2018.02.034. [PMID: 29482106] - Ariadni Geballa-Koukoula, Irene Panderi, Konstantinos Zervas, Khalil Geballa-Koukoulas, Eirini Kavvalou, Eirini Panteri-Petratou, Panagiota Vourna, Dimitra Gennimata. A porous graphitized carbon LC-ESI/MS method for the quantitation of metronidazole and fluconazole in breast milk and human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 May; 1084(?):175-184. doi:
10.1016/j.jchromb.2018.03.034. [PMID: 29604616] - Chun-Hsien Chen, Yu-Ying Chao, Yi-Hui Lin, Yen-Ling Chen. Determination of finasteride and its metabolite in urine by dispersive liquid-liquid microextraction combined with field-enhanced sample stacking and sweeping.
Journal of chromatography. A.
2018 Apr; 1547(?):14-20. doi:
10.1016/j.chroma.2018.03.008. [PMID: 29534820] - Tiele M Rizzetti, Maiara P de Souza, Osmar D Prestes, Martha B Adaime, Renato Zanella. Optimization of sample preparation by central composite design for multi-class determination of veterinary drugs in bovine muscle, kidney and liver by ultra-high-performance liquid chromatographic-tandem mass spectrometry.
Food chemistry.
2018 Apr; 246(?):404-413. doi:
10.1016/j.foodchem.2017.11.049. [PMID: 29291865] - Jakub Fibigr, Michaela Majorová, Hana Kočová Vlčková, Petr Solich, Dalibor Šatínský. A validated UHPLC method for the determination of caffeoylquinic and di-caffeoylquinic acids in green coffee extracts using an RP-Amide fused-core column.
Journal of pharmaceutical and biomedical analysis.
2018 Mar; 151(?):291-300. doi:
10.1016/j.jpba.2018.01.023. [PMID: 29413977] - Peter de Bruijn, Evelien J M Kuip, Mei-Ho Lam, Ron H J Mathijssen, Stijn L W Koolen. Bioanalytical methods for the quantification of hydromorphone, fentanyl, norfentanyl, morphine, morphine-3ß-glucuronide and morphine-6ß-glucuronide in human plasma.
Journal of pharmaceutical and biomedical analysis.
2018 Feb; 149(?):475-481. doi:
10.1016/j.jpba.2017.11.035. [PMID: 29182997] - David Paul, Lingesh Allakonda, Amit Sahu, Shruti Surendran, Nanjappan Satheeshkumar. Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in SD rats using a validated UHPLC-QTOF-MS method.
Journal of pharmaceutical and biomedical analysis.
2018 Feb; 149(?):234-241. doi:
10.1016/j.jpba.2017.11.008. [PMID: 29127904] - Aleksandra Sentkowska, Krystyna Pyrzynska. Hydrophilic interaction liquid chromatography in the speciation analysis of selenium.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Feb; 1074-1075(?):8-15. doi:
10.1016/j.jchromb.2018.01.006. [PMID: 29329094] - Mingrong Qian, Hua Yang, Zuguang Li, Yanping Liu, Jianmei Wang, Huizhen Wu, Xiaofeng Ji, Jie Xu. Detection of 13 mycotoxins in feed using modified QuEChERS with dispersive magnetic materials and UHPLC-MS/MS.
Journal of separation science.
2018 Feb; 41(3):756-764. doi:
10.1002/jssc.201700882. [PMID: 29125696] - Nur Sofiah Abu Kassim, Paul Nicholas Shaw, Amitha K Hewavitharana. Simultaneous determination of 12 vitamin D compounds in human serum using online sample preparation and liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A.
2018 Jan; 1533(?):57-65. doi:
10.1016/j.chroma.2017.12.012. [PMID: 29229333] - Anas Alshishani, Salizawati Muhamad Salhimi, Bahruddin Saad. Salting-out assisted liquid-liquid extraction coupled with hydrophilic interaction chromatography for the determination of biguanides in biological and environmental samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2018 Jan; 1073(?):51-59. doi:
10.1016/j.jchromb.2017.12.013. [PMID: 29241085]