Levistolide A (BioDeep_00000020149)
human metabolite Endogenous natural product
代谢物信息卡片
化学式: C24H28O4 (380.19874880000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC/C=C1\OC(=O)C2=C1CC[C@H]1[C@H]3C=C4C(=O)O/C(=C\CCC)[C@@]4(CC3)[C@@H]21
InChI: InChI=1S/C24H28O4/c1-3-5-7-18-16-10-9-15-14-11-12-24(21(15)20(16)23(26)27-18)17(13-14)22(25)28-19(24)8-6-4-2/h7-8,13-15,21H,3-6,9-12H2,1-2H3/b18-7-,19-8-
描述信息
Levistolide B is found in herbs and spices. Levistolide B is a constituent of Levisticum officinale (lovage)
同义名列表
7 个代谢物同义名
(1Z,5S,5aS,8Z,10bS,10cS)-1,8-dibutylidene-5,5a,6,7,8,10b-hexahydro-1H-5,10c-ethanonaphtho(1,2-c:7,8-c)difuran-3,10-dione; (6Z,16Z)-6,16-dibutylidene-5,15-dioxapentacyclo[9.5.2.0¹,¹³.0²,¹⁰.0³,⁷]octadeca-3(7),12-diene-4,14-dione; Diligustilide; Levistolide A; levistilide A; isoldiospyrin; Isodiospyrin
数据库引用编号
8 个数据库交叉引用编号
- PubChem: 73099887
- HMDB: HMDB0034225
- KNApSAcK: C00034870
- foodb: FDB012533
- CAS: 89708-23-6
- PMhub: MS000038727
- LOTUS: LTS0267994
- LOTUS: LTS0114661
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
59 个相关的物种来源信息
- 40948 - Angelica: LTS0267994
- 55605 - Angelica acutiloba: 10.1248/CPB.35.4460
- 55605 - Angelica acutiloba: LTS0267994
- 165353 - Angelica sinensis: 10.1016/S0021-9673(98)00201-5
- 165353 - Angelica sinensis: 10.1365/S10337-009-1222-9
- 165353 - Angelica sinensis: LTS0267994
- 4037 - Apiaceae: LTS0114661
- 4037 - Apiaceae: LTS0267994
- 24079 - Bignoniaceae: LTS0114661
- 52459 - Conioselinum: LTS0114661
- 52459 - Conioselinum: LTS0267994
- 2759 - Eukaryota: LTS0114661
- 2759 - Eukaryota: LTS0267994
- 9606 - Homo sapiens: -
- 48041 - Levisticum: LTS0114661
- 48041 - Levisticum: LTS0267994
- 48042 - Levisticum officinale:
- 48042 - Levisticum officinale: 10.1002/CHIN.198420334
- 48042 - Levisticum officinale: 10.1002/JLAC.198419840221
- 48042 - Levisticum officinale: LTS0114661
- 48042 - Levisticum officinale: LTS0267994
- 49551 - Ligusticum: 10.1016/J.JEP.2015.08.030
- 49551 - Ligusticum: 10.1021/NP100447A
- 49551 - Ligusticum: LTS0114661
- 49551 - Ligusticum: LTS0267994
- 2689076 - Ligusticum chuanxiong:
- 2689076 - Ligusticum chuanxiong: 10.1016/J.JEP.2015.08.030
- 2689076 - Ligusticum chuanxiong: 10.1021/NP100447A
- 2689076 - Ligusticum chuanxiong: 10.1055/S-2003-39709
- 2689076 - Ligusticum chuanxiong: 10.3987/COM-91-5877
- 2689076 - Ligusticum chuanxiong: LTS0114661
- 2689076 - Ligusticum chuanxiong: LTS0267994
- 54719 - Ligusticum porteri:
- 54719 - Ligusticum porteri: 10.1002/MRC.2767
- 54719 - Ligusticum porteri: 10.1016/J.JEP.2015.08.030
- 54719 - Ligusticum porteri: 10.1021/NP100447A
- 54719 - Ligusticum porteri: 10.1080/14786419.2010.534735
- 54719 - Ligusticum porteri: LTS0114661
- 54719 - Ligusticum porteri: LTS0267994
- 49555 - Ligusticum sinense: 10.1016/J.JEP.2015.08.030
- 49555 - Ligusticum sinense: 10.1021/NP100447A
- 49555 - Ligusticum sinense: 10.1055/S-2003-39709
- 49555 - Ligusticum sinense: 10.3987/COM-91-5877
- 49555 - Ligusticum sinense: LTS0114661
- 49555 - Ligusticum sinense: LTS0267994
- 1508160 - Ligusticum striatum:
- 3398 - Magnoliopsida: LTS0114661
- 3398 - Magnoliopsida: LTS0267994
- 239661 - Oreocome: LTS0267994
- 1508160 - Oreocome striata: LTS0267994
- 35493 - Streptophyta: LTS0114661
- 35493 - Streptophyta: LTS0267994
- 69903 - Tecoma: LTS0114661
- 69904 - Tecoma stans: 10.1016/J.JEP.2016.03.014
- 69904 - Tecoma stans: LTS0114661
- 58023 - Tracheophyta: LTS0114661
- 58023 - Tracheophyta: LTS0267994
- 33090 - Viridiplantae: LTS0114661
- 33090 - Viridiplantae: LTS0267994
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mingjie Zhang, Congyan Duan, Weifang Lin, Honghua Wu, Lu Chen, Hong Guo, Minyu Yu, Qi Liu, Yaling Nie, Hong Wang, Shaoxia Wang. Levistilide A Exerts a Neuroprotective Effect by Suppressing Glucose Metabolism Reprogramming and Preventing Microglia Polarization Shift: Implications for Parkinson's Disease.
Molecules (Basel, Switzerland).
2024 Feb; 29(4):. doi:
10.3390/molecules29040912. [PMID: 38398662] - Shu Li, Wei Zhao, Zhimin Zhao, Binbin Cheng, Shuang Li, Chenghai Liu. Levistilide A reverses rat hepatic fibrosis by suppressing angiotensin II‑induced hepatic stellate cells activation.
Molecular medicine reports.
2020 09; 22(3):2191-2198. doi:
10.3892/mmr.2020.11326. [PMID: 32705207] - Tao Guo, Zu-Long Liu, Qiang Zhao, Zhi-Min Zhao, Cheng-Hai Liu. A combination of astragaloside I, levistilide A and calycosin exerts anti-liver fibrosis effects in vitro and in vivo.
Acta pharmacologica Sinica.
2018 Sep; 39(9):1483-1492. doi:
10.1038/aps.2017.175. [PMID: 29849130] - Huining Guo, Li Sun, Shuang Ling, Jin-Wen Xu. Levistilide A Ameliorates NLRP3 Expression Involving the Syk-p38/JNK Pathway and Peripheral Obliterans in Rats.
Mediators of inflammation.
2018; 2018(?):7304096. doi:
10.1155/2018/7304096. [PMID: 30158835] - Zhi-Min Zhao, Hong-Liang Liu, Xin Sun, Tao Guo, Li Shen, Yan-Yan Tao, Cheng-Hai Liu. Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway.
Experimental biology and medicine (Maywood, N.J.).
2017 05; 242(9):974-985. doi:
10.1177/1535370217701005. [PMID: 28440736]