(+)-Conocarpan (BioDeep_00001883870)

   

natural product


代谢物信息卡片


(+)-Conocarpan

化学式: C18H18O2 (266.1307)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C/C=C/c1ccc2c(c1)[C@H](C)[C@@H](c1ccc(O)cc1)O2
InChI: InChI=1S/C18H18O2/c1-3-4-13-5-10-17-16(11-13)12(2)18(20-17)14-6-8-15(19)9-7-14/h3-12,18-19H,1-2H3/b4-3+/t12-,18-/m0/s1

描述信息

A member of the class of benzofurans that is 2,3-dihydro-1-benzofuran substituted by a methyl group at position 3, a prop-1-en-1-yl group at position 5 and a 4-hydroxyphenyl group at position 2. It is a lignan derivative isolated from the roots of Krameria lappacea.

同义名列表

1 个代谢物同义名

(+)-Conocarpan



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Guoling Yang, Hui Ma, Yanliang Wu, Baoping Zhou, Chunlei Zhang, Chengzhi Chai, Zhengyu Cao. Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2019 Jul; 129(?):281-290. doi: 10.1016/j.fct.2019.04.061. [PMID: 31054997]
  • R B L Scodro, C T A Pires, V S Carrara, C O T Lemos, L Cardozo-Filho, V A Souza, A G Corrêa, V L D Siqueira, M V C Lonardoni, R F Cardoso, D A G Cortez. Anti-tuberculosis neolignans from Piper regnellii. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2013 May; 20(7):600-4. doi: 10.1016/j.phymed.2013.01.005. [PMID: 23474218]
  • Caroline Ortega Terra Lemos, Terezinha Inez Estivalet Svidzinsk, Lilian Cristiane Baeza, Nathielle Miranda, Celso Vataru Nakamura, Diógenes Aparício Garcia Cortez, Lúcio Cardozo-Filho, Vladimir Ferreira Cabral. Evaluation of antifungal activity of extracts of Piper regnellii obtained by supercritical fluid extraction. Natural product research. 2013; 27(24):2355-9. doi: 10.1080/14786419.2013.830215. [PMID: 24007562]
  • Lisa Baumgartner, Silvio Sosa, Atanas G Atanasov, Antje Bodensieck, Nanang Fakhrudin, Julia Bauer, Giorgia Del Favero, Cristina Ponti, Elke H Heiss, Stefan Schwaiger, Angela Ladurner, Ute Widowitz, Roberto Della Loggia, Judith M Rollinger, Oliver Werz, Rudolf Bauer, Verena M Dirsch, Aurelia Tubaro, Hermann Stuppner. Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro. Journal of natural products. 2011 Aug; 74(8):1779-86. doi: 10.1021/np200343t. [PMID: 21800856]
  • Rosi Zanoni Da Silva, Rosendo Augusto Yunes, Márcia Maria de Souza, Franco Delle Monache, Valdir Cechinel-Filho. Antinociceptive properties of conocarpan and orientin obtained from Piper solmsianum C. DC. var. solmsianum (Piperaceae). Journal of natural medicines. 2010 Oct; 64(4):402-8. doi: 10.1007/s11418-010-0421-x. [PMID: 20473574]
  • S Johann, B B Cota, E M Souza-Fagundes, M G Pizzolatti, M A Resende, C L Zani. Antifungal activities of compounds isolated from Piper abutiloides Kunth. Mycoses. 2009 Nov; 52(6):499-506. doi: 10.1111/j.1439-0507.2008.01636.x. [PMID: 19076283]
  • Marina Carini, Giancarlo Aldini, Marica Orioli, Roberto Maffei Facino. Antioxidant and photoprotective activity of a lipophilic extract containing neolignans from Krameria triandra roots. Planta medica. 2002 Mar; 68(3):193-7. doi: 10.1055/s-2002-23167. [PMID: 11914952]
  • B Freixa, R Vila, E A Ferro, T Adzet, S Cañigueral. Antifungal principles from Piper fulvescens. Planta medica. 2001 Dec; 67(9):873-5. doi: 10.1055/s-2001-18838. [PMID: 11745030]
  • S A Silva, J C DE Castro, T G Da Silva, E V Da-Cunha, J M Barbosa-Filho, M S Da Silva. Krametosan, a new trinorlignan from the roots of Krameria tomentosa. Natural product letters. 2001; 15(5):323-9. doi: 10.1080/10575630108041299. [PMID: 11841116]