Micronomicin (BioDeep_00001869146)

Main id: BioDeep_00000011841

 

Chemicals and Drugs Antibiotics natural product


代谢物信息卡片


(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol

化学式: C20H41N5O7 (463.3005836)
中文名称: 小诺米星, 米诺霉素
谱图信息: 最多检出来源 () 0%

Reviewed

Last reviewed on 2024-10-09.

Cite this Page

Micronomicin. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/micronomicin (retrieved 2024-11-26) (BioDeep RN: BioDeep_00001869146). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CCC(O3)CNC)N)N)N)O
InChI: InChI=1S/C20H41N5O7/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2/h9-19,24-28H,4-8,21-23H2,1-3H3/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-/m0/s1

描述信息


Micronomicin is an antibiotic that belongs to the aminoglycoside class of organic compounds. Aminoglycosides are characterized by aminocyclitols linked to amino sugars, forming aminoglycoside antibiotics. These compounds are known for their broad-spectrum activity against various microorganisms, particularly bacteria.

Micronomicin, specifically, features a structure where an aminocyclitol is connected to an amino sugar through a glycosidic bond. This structure is typical of aminoglycosides and contributes to their antimicrobial properties. The exact configuration and arrangement of atoms in micronomicin give it its specific antimicrobial profile.

Micronomicin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=52093-21-7 (retrieved 2024-10-09) (CAS RN: 52093-21-7). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

同义名列表

2 个代谢物同义名

Micronomicin; Gentamicin C2b



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yiqiang Chen, Xiangmei Li, Lidong He, Shuheng Tang, Xilong Xiao. Immunoassays for the rapid detection of gentamicin and micronomicin in swine muscle. Journal of AOAC International. 2010 Jan; 93(1):335-42. doi: . [PMID: 20334196]
  • K Suzuki, K Takanashi. [Study of efficacy and safety of micronomicin administered by intravenous drip infusion in treatment against complicated urinary tract infections]. The Japanese journal of antibiotics. 1987 Jan; 40(1):117-35. doi: . [PMID: 3586325]
  • F Fraschini, F Scaglione, G Scarpazza, M Marchi, P C Braga. Multiple-dose pharmacokinetics in serum and sputum of sagamicin administered intramuscularly to patients. Chemotherapy. 1987; 33(2):85-92. doi: 10.1159/000238479. [PMID: 3568801]
  • F Fraschini, P C Braga, F Scaglione, A Zanollo, P Politi, R Odero, R Trazzi. Study on pulmonary, prostatic and renal (medulla and cortex) distribution of sagamicin at different time intervals. International journal of clinical pharmacology research. 1987; 7(1):51-8. doi: NULL. [PMID: 3583487]
  • M Watanabe, N Kaneniwa, M Matsumoto, K Mashimo. Three-compartment open model analysis of micronomicin in man. Journal of pharmacobio-dynamics. 1986 Oct; 9(10):783-6. doi: 10.1248/bpb1978.9.783. [PMID: 3820054]
  • H Tanimura, S Mukaihara, M Setoyama, M Yung, H Kato, F Yotsumoto, M Nakano. [Chemotherapy in biliary tract infections (XXX). Special reference to the concentration of micronomicin in human gallbladder tissues and bile]. The Japanese journal of antibiotics. 1985 Nov; 38(11):3087-96. doi: . [PMID: 4094048]
  • K Matsumoto, H Shishido, A Takahashi. [Pharmacokinetic and clinical evaluations of micronomicin by intravenous drip infusion]. The Japanese journal of antibiotics. 1985 Jun; 38(6):1557-65. doi: . [PMID: 4046177]
  • M Watanabe, I Saito, S Mitsuhashi, M Koyama, Y Kawaguchi. [Clinical studies of intravenous drip infusion of micronomicin. 1. Pharmacokinetics (Part 2). Intravenous Micronomicin Research Group]. The Japanese journal of antibiotics. 1985 Apr; 38(4):1086-92. doi: . [PMID: 4032720]
  • H Oshitani, H Takeda, T Nihei, H Kobayashi. [Fundamental and clinical studies of intravenous drip infusion of micronomicin in respiratory tract infection]. The Japanese journal of antibiotics. 1984 Sep; 37(9):1603-6. doi: . [PMID: 6512979]
  • T Kawamoto, I Mashimo, S Yamauchi, M Watanabe. Determination of sisomicin, netilmicin, astromicin and micronomicin in serum by high-performance liquid chromatography. Journal of chromatography. 1984 Feb; 305(2):373-9. doi: 10.1016/s0378-4347(00)83351-4. [PMID: 6707164]
  • D Savoia, P Martinetto, A Achino, A Pugliese. Adhesion of Proteus species to various cell types. European journal of clinical microbiology. 1983 Dec; 2(6):571-6. doi: 10.1007/bf02016568. [PMID: 6667683]
  • T Hara, S Harada, M Yamamoto, J Kashitani, T Deguchi. [Safety evaluation of micronomicin V. Subacute toxicity in rats after intravenous injection]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3208-25. doi: . [PMID: 6674533]
  • T Hara, S Harada, T Ikenaga, M Yamamoto, J Kashitani, T Deguchi. [Safety evaluation of micronomicin VI. Subacute toxicity in rabbits after drip intravenous infusion]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3226-38. doi: . [PMID: 6674534]
  • K Okada, N Kawamura, M Ohkoshi, S Nemoto, T Oda, N Ikeda. [Clinical study on intravenous infusion of micronomicin]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3302-11. doi: . [PMID: 6674543]
  • A Inoue, T Hara, T Deguchi. [Pharmacokinetic studies on micronomicin in dogs. Comparison of intramuscular and drip intravenous administration models]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3262-7. doi: NULL. [PMID: 6674539]
  • T Kurimoto, H Kobayashi, A Inoue, T Deguchi, R Okachi. [Pharmacokinetic studies on micronomicin in rats. Comparison of intramuscular and drip intravenous administration models]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3254-61. doi: NULL. [PMID: 6674538]
  • F Yamasaku. [Pharmacokinetic studies of micronomicin using a continuous intravenous infusion method]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3283-90. doi: NULL. [PMID: 6674541]
  • M Watanabe, M Koyama. [Clinical studies of intravenous drip infusion of micronomicin. 1. Absorption and excretion]. The Japanese journal of antibiotics. 1983 Nov; 36(11):3291-301. doi: NULL. [PMID: 6674542]
  • T Hara, S Nishikawa, H Miyazaki, Y Ohguro. [Safety evaluation of micronomicin. I. Subacute and chronic toxicity in dogs]. The Japanese journal of antibiotics. 1983 Jan; 36(1):150-73. doi: . [PMID: 6842822]
  • NULL. [Micronomicin preparation]. The Japanese journal of antibiotics. 1983 Jan; 36(1):209-12. doi: NULL. [PMID: 6341655]
  • M Ohkoshi, K Okada, N Kawamura. [Review [new antibiotics series III]: micronomicin (author's transl)]. The Japanese journal of antibiotics. 1982 Mar; 35(3):691-703. doi: . [PMID: 7047790]
  • J P Bendirdjian, B Foucher, J P Fillastre. Comparative study of the effects of sagamicin, 1 N-HABA-sagamicin, UK-4, Sch 21420, gentamicin and amikacin on the respiration activity of isolated rat kidney mitochondria. The Journal of antibiotics. 1980 Nov; 33(11):1383-5. doi: 10.7164/antibiotics.33.1383. [PMID: 7251478]
  • . [Basic and clinical studies on KW-1062 at daily dose of 240 and 360 mg in the field of urology (author's transl)]. The Japanese journal of antibiotics. 1980 Apr; 33(4):526-38. doi: . [PMID: 6997537]
  • T Hara, S Nishikawa, H Miyazaki, Y Ohguro. [Studies on the safety of KW-1062 (fifth report). A comparative study on the renal toxicity of KW-1062 and gentamicin in rats by ligh and electron microscopies (author's transl)]. The Japanese journal of antibiotics. 1980 Jan; 33(1):1-9. doi: . [PMID: 7373849]
  • T Deguchi, S Okumura, M Shimizu. [Radioimmunoassay of 125I-sagamicin (author's transl)]. The Japanese journal of antibiotics. 1978 Mar; 31(3):149-52. doi: . [PMID: 650888]
  • T Hashimoto, S Ichikawa, T Kojima. [The general pharmacological actions of KW-1062, a new aminoglycoside antibiotic (author's transl)]. The Japanese journal of antibiotics. 1977 Jun; 30(6):362-85. doi: . [PMID: 894835]
  • T Hara, K Koyama, H Miyazaki, Y Ohguro, M Shimizu. [Safety evaluation of KW-1062. I. Acute toxicity in mice, rats and dogs, subacute and chronic toxicity in rats (author's transl)]. The Japanese journal of antibiotics. 1977 Jun; 30(6):386-407. doi: NULL. [PMID: 894836]