D-galactonic acid (BioDeep_00001868598)

Main id: BioDeep_00000014350

 


代谢物信息卡片


D-galactonic acid

化学式: C6H12O7 (196.0583)
中文名称: D-半乳糖酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(C(C(C(=O)O)O)O)O)O)O
InChI: InChI=1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3+,4+,5-/m1/s1

描述信息

A galactonic acid compound having D-configuration.

同义名列表

2 个代谢物同义名

D-galactonic acid; D-Galactonate



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

8 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Tsubasa Sodeyama, Hitoshi Nishikawa, Kenji Harai, Daiki Takeshima, Yoshihiro Sawa, Takanori Maruta, Takahiro Ishikawa. The d-mannose/l-galactose pathway is the dominant ascorbate biosynthetic route in the moss Physcomitrium patens. The Plant journal : for cell and molecular biology. 2021 09; 107(6):1724-1738. doi: 10.1111/tpj.15413. [PMID: 34245628]
  • Jonathan B Leano, Samir Batarni, Jacob Eriksen, Narinobu Juge, John E Pak, Tomomi Kimura-Someya, Yaneth Robles-Colmenares, Yoshinori Moriyama, Robert M Stroud, Robert H Edwards. Structures suggest a mechanism for energy coupling by a family of organic anion transporters. PLoS biology. 2019 05; 17(5):e3000260. doi: 10.1371/journal.pbio.3000260. [PMID: 31083648]
  • Nathalie Vionnet, Linda H Münger, Carola Freiburghaus, Kathryn J Burton, Grégory Pimentel, François P Pralong, René Badertscher, Guy Vergères. Assessment of lactase activity in humans by measurement of galactitol and galactonate in serum and urine after milk intake. The American journal of clinical nutrition. 2019 02; 109(2):470-477. doi: 10.1093/ajcn/nqy296. [PMID: 30721917]
  • Lisha Zhang, Harry Thiewes, Jan A L van Kan. The D-galacturonic acid catabolic pathway in Botrytis cinerea. Fungal genetics and biology : FG & B. 2011 Oct; 48(10):990-7. doi: 10.1016/j.fgb.2011.06.002. [PMID: 21683149]
  • Tomiko Kuhara, Morimasa Ohse, Yoshito Inoue, Arthur J L Cooper. A GC/MS-based metabolomic approach for diagnosing citrin deficiency. Analytical and bioanalytical chemistry. 2011 Jun; 400(7):1881-94. doi: 10.1007/s00216-011-4766-0. [PMID: 21365350]
  • Julia B Hennermann, Peter Schadewaldt, Barbara Vetter, Yoon S Shin, Eberhard Mönch, Jeannette Klein. Features and outcome of galactokinase deficiency in children diagnosed by newborn screening. Journal of inherited metabolic disease. 2011 Apr; 34(2):399-407. doi: 10.1007/s10545-010-9270-8. [PMID: 21290184]
  • Phuc Thi Do, Marion Prudent, Ronan Sulpice, Mathilde Causse, Alisdair R Fernie. The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. Plant physiology. 2010 Nov; 154(3):1128-42. doi: 10.1104/pp.110.163030. [PMID: 20841452]
  • Stephen J Bruce, Isabelle Breton, Jacques Decombaz, Chris Boesch, Eva Scheurer, Ivan Montoliu, Serge Rezzi, Sunil Kochhar, Philippe A Guy. A plasma global metabolic profiling approach applied to an exercise study monitoring the effects of glucose, galactose and fructose drinks during post-exercise recovery. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2010 Nov; 878(29):3015-23. doi: 10.1016/j.jchromb.2010.09.004. [PMID: 20933482]
  • Jiao Wu, Yali Zhang, Huiqin Zhang, Hong Huang, Kevin M Folta, Jiang Lu. Whole genome wide expression profiles of Vitis amurensis grape responding to downy mildew by using Solexa sequencing technology. BMC plant biology. 2010 Oct; 10(?):234. doi: 10.1186/1471-2229-10-234. [PMID: 21029438]
  • Marilyn G Wiebe, Dominik Mojzita, Satu Hilditch, Laura Ruohonen, Merja Penttilä. Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi. BMC biotechnology. 2010 Aug; 10(?):63. doi: 10.1186/1472-6750-10-63. [PMID: 20796274]
  • Antonio Di Matteo, Adriana Sacco, Milena Anacleria, Mario Pezzotti, Massimo Delledonne, Alberto Ferrarini, Luigi Frusciante, Amalia Barone. The ascorbic acid content of tomato fruits is associated with the expression of genes involved in pectin degradation. BMC plant biology. 2010 Aug; 10(?):163. doi: 10.1186/1471-2229-10-163. [PMID: 20691085]
  • Can Ficicioglu, Christie Hussa, Paul R Gallagher, Nina Thomas, Claire Yager. Monitoring of biochemical status in children with Duarte galactosemia: utility of galactose, galactitol, galactonate, and galactose 1-phosphate. Clinical chemistry. 2010 Jul; 56(7):1177-82. doi: 10.1373/clinchem.2010.144097. [PMID: 20489133]
  • Benoît Remenant, Bénédicte Coupat-Goutaland, Alice Guidot, Gilles Cellier, Emmanuel Wicker, Caitilyn Allen, Mark Fegan, Olivier Pruvost, Mounira Elbaz, Alexandra Calteau, Gregory Salvignol, Damien Mornico, Sophie Mangenot, Valérie Barbe, Claudine Médigue, Philippe Prior. Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence. BMC genomics. 2010 Jun; 11(?):379. doi: 10.1186/1471-2164-11-379. [PMID: 20550686]
  • José M Peregrín-Alvarez, Chris Sanford, John Parkinson. The conservation and evolutionary modularity of metabolism. Genome biology. 2009; 10(6):R63. doi: 10.1186/gb-2009-10-6-r63. [PMID: 19523219]
  • Joost T van Dongen, Anja Fröhlich, Santiago J Ramírez-Aguilar, Nicolas Schauer, Alisdair R Fernie, Alexander Erban, Joachim Kopka, Jeremy Clark, Anke Langer, Peter Geigenberger. Transcript and metabolite profiling of the adaptive response to mild decreases in oxygen concentration in the roots of arabidopsis plants. Annals of botany. 2009 Jan; 103(2):269-80. doi: 10.1093/aob/mcn126. [PMID: 18660497]
  • Widodo, John H Patterson, Ed Newbigin, Mark Tester, Antony Bacic, Ute Roessner. Metabolic responses to salt stress of barley (Hordeum vulgare L.) cultivars, Sahara and Clipper, which differ in salinity tolerance. Journal of experimental botany. 2009; 60(14):4089-103. doi: 10.1093/jxb/erp243. [PMID: 19666960]
  • Sze Kwan Lam, Tzi Bun Ng. Novel galactonic acid-binding hexameric lectin from Hibiscus mutabilis seeds with antiproliferative and potent HIV-1 reverse transcriptase inhibitory activities. Acta biochimica Polonica. 2009; 56(4):649-54. doi: 10.18388/abp.2009_2498. [PMID: 19956805]
  • Kyung-Bum Lee, Philippe De Backer, Toshihiro Aono, Chi-Te Liu, Shino Suzuki, Tadahiro Suzuki, Takakazu Kaneko, Manabu Yamada, Satoshi Tabata, Doris M Kupfer, Fares Z Najar, Graham B Wiley, Bruce Roe, Tim T Binnewies, David W Ussery, Wim D'Haeze, Jeroen Den Herder, Dirk Gevers, Danny Vereecke, Marcelle Holsters, Hiroshi Oyaizu. The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571. BMC genomics. 2008 Jun; 9(?):271. doi: 10.1186/1471-2164-9-271. [PMID: 18522759]
  • Miyako Kusano, Atsushi Fukushima, Masanori Arita, Pär Jonsson, Thomas Moritz, Makoto Kobayashi, Naomi Hayashi, Takayuki Tohge, Kazuki Saito. Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. BMC systems biology. 2007 Nov; 1(?):53. doi: 10.1186/1752-0509-1-53. [PMID: 18028551]
  • Stefan Kempa, Wilfried Rozhon, Jozef Samaj, Alexander Erban, Frantisek Baluska, Thomas Becker, Joachim Haselmayer, Enrico Schleiff, Joachim Kopka, Heribert Hirt, Claudia Jonak. A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism. The Plant journal : for cell and molecular biology. 2007 Mar; 49(6):1076-90. doi: 10.1111/j.1365-313x.2006.03025.x. [PMID: 17319843]
  • Suzanne Wehrli, Robert Reynolds, Stanton Segal. Metabolic fate of administered [13C]galactose in tissues of galactose-1-phosphate uridyl transferase deficient mice determined by nuclear magnetic resonance. Molecular genetics and metabolism. 2007 Jan; 90(1):42-8. doi: 10.1016/j.ymgme.2006.07.007. [PMID: 16935536]
  • Loredana De Bartolo, Sabrina Morelli, Maria Rende, Simona Salerno, Lidietta Giorno, Linda C Lopez, Pietro Favia, Riccardo d'Agostino, Enrico Drioli. Galactose derivative immobilized glow discharge processed polyethersulfone membranes maintain the liver cell metabolic activity. Journal of nanoscience and nanotechnology. 2006 Aug; 6(8):2344-53. doi: 10.1166/jnn.2006.514. [PMID: 17037840]
  • Claire Yager, Suzanne Wehrli, Stanton Segal. Urinary galactitol and galactonate quantified by isotope-dilution gas chromatography-mass spectrometry. Clinica chimica acta; international journal of clinical chemistry. 2006 Apr; 366(1-2):216-24. doi: 10.1016/j.cca.2005.10.015. [PMID: 16336956]
  • Boonchai Boonyawat, Mahattana Kamolsilp, Nopaorn Phavichitr. Galactosemia in Thai patient at Phramongkutklao Hospital: a case report. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2005 Nov; 88 Suppl 3(?):S275-80. doi: NULL. [PMID: 16858969]
  • Keith R Ridel, Nancy D Leslie, Donald L Gilbert. An updated review of the long-term neurological effects of galactosemia. Pediatric neurology. 2005 Sep; 33(3):153-61. doi: 10.1016/j.pediatrneurol.2005.02.015. [PMID: 16087312]
  • Peter Schadewaldt, Hans-Werner Hammen, Sara Stolpmann, Loganathan Kamalanathan, Udo Wendel. Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Mar; 801(2):249-55. doi: 10.1016/j.jchromb.2003.11.020. [PMID: 14751793]
  • Claire Yager, Cong Ning, Robert Reynolds, Nancy Leslie, Stanton Segal. Galactitol and galactonate accumulation in heart and skeletal muscle of mice with deficiency of galactose-1-phosphate uridyltransferase. Molecular genetics and metabolism. 2004 Feb; 81(2):105-11. doi: 10.1016/j.ymgme.2003.10.001. [PMID: 14741191]
  • Peter Schadewaldt, Loganathan Kamalanathan, Hans Werner Hammen, Udo Wendel. Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients. Molecular genetics and metabolism. 2004 Jan; 81(1):31-44. doi: 10.1016/j.ymgme.2003.10.007. [PMID: 14728989]
  • Cornelia Wagner, Michael Sefkow, Joachim Kopka. Construction and application of a mass spectral and retention time index database generated from plant GC/EI-TOF-MS metabolite profiles. Phytochemistry. 2003 Mar; 62(6):887-900. doi: 10.1016/s0031-9422(02)00703-3. [PMID: 12590116]
  • Silvano Onofri, Donatella Barreca, Isabella Garuccio. Effects of lycorine on growth and effects of L-galactonic acid-gamma-lactone on ascorbic acid biosynthesis in strains of Cryptococcus laurentii isolated from Narcissus pseudonarcissus roots and bulbs. Antonie van Leeuwenhoek. 2003; 83(1):57-61. doi: 10.1023/a:1022903504795. [PMID: 12755480]
  • C Ning, R Reynolds, J Chen, C Yager, G T Berry, N Leslie, S Segal. Galactose metabolism in mice with galactose-1-phosphate uridyltransferase deficiency: sucklings and 7-week-old animals fed a high-galactose diet. Molecular genetics and metabolism. 2001 Apr; 72(4):306-15. doi: 10.1006/mgme.2001.3152. [PMID: 11286504]
  • Z Chao, B He. [Studies on chemical constituents from fruits of Trichosanthes kirilowii Maxim]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1999 Oct; 24(10):612-3, 638. doi: ". [PMID: 12205958]
  • J Y Eu, C Y Wang, J Andrade. Homogeneous bioluminescence assay for galactosuria: interference and kinetic analysis. Analytical biochemistry. 1999 Jul; 271(2):168-76. doi: 10.1006/abio.1999.4137. [PMID: 10419632]
  • S L Wehrli, G T Berry, M Palmieri, A Mazur, L Elsas, S Segal. Urinary galactonate in patients with galactosemia: quantitation by nuclear magnetic resonance spectroscopy. Pediatric research. 1997 Dec; 42(6):855-61. doi: 10.1203/00006450-199712000-00022. [PMID: 9396569]