Dinoprostone (BioDeep_00001867832)

Main id: BioDeep_00000001683

 

PANOMIX_OTCML-2023


代谢物信息卡片


Dinoprostone

化学式: C20H32O5 (352.2249622)
中文名称: 地诺前列酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
InChI: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1

描述信息

G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02A - Uterotonics > G02AD - Prostaglandins
D012102 - Reproductive Control Agents > D010120 - Oxytocics
C78568 - Prostaglandin Analogue
Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

同义名列表

3 个代谢物同义名

Dinoprostone; PGE2; Prostaglandin E2



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(11)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

14 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yazhen Xie, Haifeng Xu, Zhijuan Gu. Ge-gen decoction alleviates primary dysmenorrhoea symptoms in a rat model. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. 2024 Dec; 44(1):2337691. doi: 10.1080/01443615.2024.2337691. [PMID: 38594870]
  • Xiaoying Wu, Li Li, Jinhabure, Xiaofeng, Eerdunchaolu. Radix Sophorae Flavescentis of Sophora flavescens Aiton inhibits LPS-induced macrophage pro-inflammatory response via regulating CFHR2 expression. Journal of ethnopharmacology. 2024 Sep; 331(?):118210. doi: 10.1016/j.jep.2024.118210. [PMID: 38641074]
  • Larisse Ricardo Gadelha, Maria Juliana Bezerra Costa, João Paulo Alecrim de Abreu, Larissa Paola Rodrigues Venancio, Mary Hellen Fabres-Klein, Raphael Contelli Klein, Jonilson Berlink Lima, Théo Araújo-Santos. Prostaglandin E2/Leukotriene B4 balance and viral load in distinct clinical stages of COVID-19: A cross-sectional study. Prostaglandins & other lipid mediators. 2024 Jun; 172(?):106820. doi: 10.1016/j.prostaglandins.2024.106820. [PMID: 38346573]
  • Ian E Cock. Terminalia ferdinandiana Exell. extracts reduce pro-inflammatory cytokine and PGE2 secretion, decrease COX-2 expression and down-regulate cytosolic NF-κB levels. Inflammopharmacology. 2024 Jun; 32(3):1839-1853. doi: 10.1007/s10787-024-01462-7. [PMID: 38581641]
  • Karen T Feehan, Hannah E Bridgewater, Jan Stenkiewicz-Witeska, Roel P H De Maeyer, John Ferguson, Matthias Mack, Jeremy Brown, Giuseppe Ercoli, Connar M Mawer, Arne N Akbar, James R W Glanville, Parinaaz Jalali, Olivia V Bracken, Anna Nicolaou, Alexandra C Kendall, Michelle A Sugimoto, Derek W Gilroy. Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia. Nature communications. 2024 May; 15(1):4326. doi: 10.1038/s41467-024-48138-y. [PMID: 38773113]
  • Luisa Frusciante, Michela Geminiani, Alfonso Trezza, Tommaso Olmastroni, Pierfrancesco Mastroeni, Laura Salvini, Stefania Lamponi, Andrea Bernini, Daniela Grasso, Elena Dreassi, Ottavia Spiga, Annalisa Santucci. Phytochemical Composition, Anti-Inflammatory Property, and Anti-Atopic Effect of Chaetomorpha linum Extract. Marine drugs. 2024 May; 22(5):. doi: 10.3390/md22050226. [PMID: 38786617]
  • Zhi-Qiang Lin, Yao Yao, Yu-Fei Zhang, Xiao-Yan Zhang, You-Fei Guan. Role of prostaglandin E2 and its receptors in chronic liver disease. Sheng li xue bao : [Acta physiologica Sinica]. 2024 Apr; 76(2):329-340. doi: ". [PMID: 38658381]
  • Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol. Journal of ethnopharmacology. 2024 Apr; 323(?):117616. doi: 10.1016/j.jep.2023.117616. [PMID: 38142877]
  • Shu-Tao Chen, Shuang Ji, Mei-Na Guo, Li-Hong Chen. [Research advances of prostaglandin E2 receptor 1 (EP1)]. Sheng li xue bao : [Acta physiologica Sinica]. 2024 Feb; 76(1):105-118. doi: ". [PMID: 38444136]
  • Guo-Liang Shao, Shao-Lei Huang, Rui Li, Dian-Hui Yang, Meng-Meng Wang. The curative efficacy of auricular comprehensive therapy on menstrual migraine and its effect on serum prostaglandin. Zhen ci yan jiu = Acupuncture research. 2024 Feb; 49(2):177-184. doi: 10.13702/j.1000-0607.20221424. [PMID: 38413039]
  • Cheng-Chao Xu, Xu-Hao Li, Jin-Ling Li. Comparative study on curative effect and recurrence rate of chronic scapulohumeral periarthritis treated with different acupuncture techniques. Zhen ci yan jiu = Acupuncture research. 2024 Feb; 49(2):164-170. doi: 10.13702/j.1000-0607.20221004. [PMID: 38413037]
  • Yiyun Geng, Weichao Li, Nai-Kei Wong, Fuchong Xue, Qing Li, Yang Zhang, Jingyuan Xu, Zhangshuang Deng, Yiqing Zhou. Discovery of Artemisinins as Microsomal Prostaglandins Synthase-2 Inhibitors for the Treatment of Colorectal Cancer via Chemoproteomics. Journal of medicinal chemistry. 2024 Feb; 67(3):2083-2094. doi: 10.1021/acs.jmedchem.3c01989. [PMID: 38287228]
  • Xin Qi, Xin Chen, Wen-Bo An, Zhi-Ming Xu, Duo-Xian Wang, Peng-Fei Luo, Yi-Xin Chen, Jiao-Jiao Ma, Zi-Yang Hu, Wei Qi, Jian-Jun Liu, Jun-Xi Liu. [Ligusticum cycloprolactam inhibits IL-1β-induced apoptosis and inflammation of rat chondrocytes via HMGB1/TLR4/NF-κB signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2024 Feb; 49(4):1007-1016. doi: 10.19540/j.cnki.cjcmm.20230904.401. [PMID: 38621908]
  • Yingke Liu, Jiao He, Man Li, Kebai Ren, Zhihe Zhao. Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression. ACS applied materials & interfaces. 2024 Feb; ?(?):. doi: 10.1021/acsami.3c17357. [PMID: 38300288]
  • Yuan Sun, Zhaoyao Qi, Yuanhui Xu, Chenyang Li, Jun Zhao, Tao Liu. Anti-inflammatory, analgesic, antitussive and antipyretic activities of polyphenol-enriched fraction from Nymphaea candida. Journal of ethnopharmacology. 2024 Jan; 324(?):117789. doi: 10.1016/j.jep.2024.117789. [PMID: 38266950]
  • Huina Ma, Hehua Huang, Chenyu Li, Shasha Li, Juefang Gan, Chunrong Lian, Yanwu Ling. The antidepressive mechanism of Longya Lilium combined with Fluoxetine in mice with depression-like behaviors. NPJ systems biology and applications. 2024 Jan; 10(1):5. doi: 10.1038/s41540-024-00329-5. [PMID: 38218856]
  • Luís Almeida, Ruthger van Roey, Thiago Andrade Patente, Frank Otto, Tom Veldhuizen, Mohan Ghorasaini, Angela van Diepen, Gabriele Schramm, Jianyang Liu, Helena Idborg, Marina Korotkova, Per-Johan Jakobsson, Martin Giera, Cornelis Hendrik Hokke, Bart Everts. High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2. Frontiers in immunology. 2024; 15(?):1372927. doi: 10.3389/fimmu.2024.1372927. [PMID: 38742105]
  • Quanxin Wang, Ruiqi Zhang, Yijun He, Guangmin Mao, Zhaolu Kong. Taraxasterol enhanced bladder cancer cells radiosensitivity via inhibiting the COX-2/PGE2/JAK2/STAT3/MMP pathway. International journal of radiation biology. 2024; 100(5):791-801. doi: 10.1080/09553002.2024.2324475. [PMID: 38442139]
  • V A Shipelin, N A Biryulina, Yu S Sidorova, N A Petrov, S N Zorin, V K Mazo, V V Bessonov. [Physiological and biochemical in vivo study of polyphenols and 20-hydroxyecdisone from quinoa grains effect on resistance to physical exercise in Wistar rats]. Voprosy pitaniia. 2024; 93(1):80-91. doi: 10.33029/0042-8833-2024-93-1-80-91. [PMID: 38555612]
  • Yifei Xu, Linsun Lin, Huantian Zheng, Siyuan Xu, Xinxin Hong, Tiantian Cai, Jianqu Xu, Weijian Zhang, Yanzhen Mai, Jingwei Li, Bin Huang, Zhu Liu, Shaoju Guo. Protective effect of Amauroderma rugosum ethanol extract and its primary bioactive compound, ergosterol, against acute gastric ulcers based on LXR-mediated gastric mucus secretions. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155236. doi: 10.1016/j.phymed.2023.155236. [PMID: 38016383]
  • Mario F C Santos, Karen de J Nicácio, Albert Katchborian-Neto, Miller S Ferreira, Daniel de Oliveira Miranda, João V Andrade, Herinque de A Pereira, Ester Gonçalves de Jesus, Thamires B, Silva Souza, Raquel P Morais-Urano, Danielle Ferreira Dias, Daniela A Chagas-Paula, Marisi G Soares. Ex vivo inhibition of PGE2 formation in human blood by four bicyclico [3.2.1] octane neolignans isolated from Aniba firmula bark, two with unusual structural pattern. Natural product research. 2024 Jan; 38(3):393-401. doi: 10.1080/14786419.2022.2124248. [PMID: 36106991]
  • Jorge Cuenca-Escalona, Georgina Flórez-Grau, Koen van den Dries, Alessandra Cambi, I Jolanda M de Vries. PGE2-EP4 signaling steers cDC2 maturation toward the induction of suppressive T-cell responses. European journal of immunology. 2023 Dec; ?(?):e2350770. doi: 10.1002/eji.202350770. [PMID: 38088451]
  • Xu Yang, Yunyuan Tian, Jincai Liu, Yaoyao Kou, Yanhua Xie, Siwang Wang, Ye Zhao. Peony Pollen Protects against Primary Dysmenorrhea in Mice by Inhibiting Inflammatory Response and Regulating the COX2/PGE2 Pathway. International journal of molecular sciences. 2023 Dec; 24(24):. doi: 10.3390/ijms242417245. [PMID: 38139073]
  • Stefan Gahbauer, Chelsea DeLeon, Joao M Braz, Veronica Craik, Hye Jin Kang, Xiaobo Wan, Xi-Ping Huang, Christian B Billesbølle, Yongfeng Liu, Tao Che, Ishan Deshpande, Madison Jewell, Elissa A Fink, Ivan S Kondratov, Yurii S Moroz, John J Irwin, Allan I Basbaum, Bryan L Roth, Brian K Shoichet. Docking for EP4R antagonists active against inflammatory pain. Nature communications. 2023 Dec; 14(1):8067. doi: 10.1038/s41467-023-43506-6. [PMID: 38057319]
  • Mengyao Song, Cheng Qian, Teng Zhang, Yu Tang, Yueke Zhou, Zhonghong Wei, Aiyun Wang, Chongjin Zhong, Yang Zhao, Yin Lu. Salvia mitiorrhiza Bunge aqueous extract attenuates infiltration of tumor-associated macrophages and potentiates anti-PD-L1 immunotherapy in colorectal cancer through modulating Cox2/PGE2 cascade. Journal of ethnopharmacology. 2023 Nov; 316(?):116735. doi: 10.1016/j.jep.2023.116735. [PMID: 37286115]
  • Taylor Richards, Scarlett Burron, Terence Connor McCorkell, Luciano Trevizan, Keely Patterson, Debbie Minikhiem, David W L Ma, Wendy Pearson, Anna K Shoveller. Effects of dietary camelina, flaxseed, and canola oil supplementation on transepidermal water loss, skin and coat health parameters, and plasma prostaglandin E2, glycosaminoglycan, and nitric oxide concentrations in healthy adult horses. Journal of animal science. 2023 Nov; ?(?):. doi: 10.1093/jas/skad373. [PMID: 37935917]
  • Albert Katchborian-Neto, Karen de Jesus Nicácio, Jonas C Cruz, Paula Carolina Pires Bueno, Michael Murgu, Danielle F Dias, Marisi G Soares, Ana C C Paula, Daniela A Chagas-Paula. Bioprospecting-based untargeted metabolomics identifies alkaloids as potential anti-inflammatory bioactive markers of Ocotea species (Lauraceae). Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Nov; 120(?):155060. doi: 10.1016/j.phymed.2023.155060. [PMID: 37717309]
  • Lisbeth Berrueta, Dennis Muñoz-Vergara, Daniel Martin, Rebecca Thompson, Brian E Sansbury, Matthew Spite, Gary J Badger, Helene M Langevin. Effect of stretching on inflammation in a subcutaneous carrageenan mouse model analyzed at single-cell resolution. Journal of cellular physiology. 2023 Nov; ?(?):. doi: 10.1002/jcp.31133. [PMID: 37909412]
  • Xu Yifei, Hong Xinxin, Luo Liuru, Lin Yandan, Li Jingwei, Li Haiwen, Guo Shaoju, Huang Bin. Anti-inflammatory effects of Weiyan I decoction against gastric ulcers in a rat model via inhibition of p38 mitogen-activated protein kinases signaling. Pakistan journal of pharmaceutical sciences. 2023 Nov; 36(6):1809-1822. doi: . [PMID: 38124422]
  • Liu-Jun Wu, Yan Chen, Zi-Wei Lin, Chen Sun, Liang Xiong, Xiao-Fang Xie, Cheng Peng. [Therapeutic effect of Leonuri Herba aqueous decoction on primary dysmenorrhea in rats and its metabolomic analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Nov; 48(22):6093-6106. doi: 10.19540/j.cnki.cjcmm.20230803.401. [PMID: 38114217]
  • Kiran Mashaal, Arham Shabbir, Muhammad Shahzad, Aisha Mobashar, Tasleem Akhtar, Tabinda Fatima, Bushra Riaz, Rana Alharbi, Afreen Fatima, Abdulkareem A Alanezi, Ashfaq Ahmad. Amelioration of Rheumatoid Arthritis by Fragaria nubicola (Wild Strawberry) via Attenuation of Inflammatory Mediators in Sprague Dawley Rats. Medicina (Kaunas, Lithuania). 2023 Oct; 59(11):. doi: 10.3390/medicina59111917. [PMID: 38003966]
  • Chien-Chung Yang, I-Ta Lee, Yan-Jyun Lin, Wen-Bin Wu, Li-Der Hsiao, Chuen-Mao Yang. Thrombin-Induced COX-2 Expression and PGE2 Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015130. [PMID: 37894811]
  • Dong Liu, Fei Tang, Li Zhang, Jing-Nan Zhang, Xiao-Lan Zhao, Li-Yue Xu, Cheng Peng, Hui Ao. Alpinia katsumadai Hayata Volatile Oil Is Effective in Treating 5-Fluorouracil-Induced Mucositis by Regulating Gut Microbiota and Modulating the GC/GR Pathway and the mPGES-1/PGE2/EP4 Pathways. Journal of agricultural and food chemistry. 2023 Oct; ?(?):. doi: 10.1021/acs.jafc.3c05051. [PMID: 37800952]
  • Rui Wang, Xiu-Qin Li, Meng-Ru Wang, Xiu-Mei Wu, Yu-Sheng Xu, Ahunova Hilola, Xue-Chang Wang, Heng Liu. Effect of Kangfuxiaomi suppository on pelvic inflammatory disease in rats. Journal of reproductive immunology. 2023 Sep; 160(?):104154. doi: 10.1016/j.jri.2023.104154. [PMID: 37774536]
  • Sophie Morin, Andréa Tremblay, Elizabeth Dumais, Pierre Julien, Nicolas Flamand, Roxane Pouliot. Eicosapentaenoic Acid Influences the Lipid Profile of an In Vitro Psoriatic Skin Model Produced with T Cells. Biomolecules. 2023 09; 13(9):. doi: 10.3390/biom13091413. [PMID: 37759812]
  • Sara Sattar, Arham Shabbir, Muhammad Shahzad, Tasleem Akhtar, Arfan Ahmad, Sulaiman Mohammed Alnasser, Bushra Riaz, Shaik Karimullah, Ashfaq Ahmad. Eichhornia crassipes Ameliorated Rheumatoid Arthritis by Modulating Inflammatory Cytokines and Metalloproteinase Enzymes in a Rat Model. Medicina (Kaunas, Lithuania). 2023 Sep; 59(9):. doi: 10.3390/medicina59091594. [PMID: 37763713]
  • Michael Kurz, Michaela Ulrich, Alwina Bittner, Magdalena Martina Scharf, Jingchen Shao, Imke Wallenstein, Horst Lemoine, Nina Wettschureck, Peter Kolb, Moritz Bünemann. EP4 Receptor Conformation Sensor Suited for Ligand Screening and Imaging of Extracellular Prostaglandins. Molecular pharmacology. 2023 09; 104(3):80-91. doi: 10.1124/molpharm.122.000648. [PMID: 37442628]
  • Pingping Lv, Huirong Zhang, Meiling Tai, Biao Che, Dan Yu, Ying Zhang, Haodong Li, Xianyao Meng, Miaomiao Guo, Li Li. Active Ingredients of Schisandra chinensis Fruit Oil and their Effect on Propionibacterium acnes-Induced Inflammation in HaCaT Cells. Frontiers in bioscience (Landmark edition). 2023 08; 28(8):177. doi: 10.31083/j.fbl2808177. [PMID: 37664918]
  • Bruno Anderson Fernandes da Silva, Renata Torres Pessoa, Roger Henrique Sousa da Costa, Maria Rayane Correia de Oliveira, Andreza Guedes Barbosa Ramos, Maria Gabriely de Lima Silva, Lucas Yure Santos da Silva, Cassio Rocha Medeiros, Sloana Giesta Lemos Florencio, Jaime Ribeiro-Filho, Henrique Douglas Melo Coutinho, António Raposo, Sunghoon Yoo, Heesup Han, Irwin Rose Alencar de Menezes, Lucindo José Quintans Júnior. Evaluation of the antiedematogenic and anti-inflammatory properties of Ximenia americana L. (Olacaceae) bark extract in experimental models of inflammation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Aug; 166(?):115249. doi: 10.1016/j.biopha.2023.115249. [PMID: 37597323]
  • Yang Jiao, Ti Zhang, Mei Liu, Luyang Zhou, Mengzhi Qi, Xin Xie, Xueyin Shi, Xiaoping Gu, Zhengliang Ma. Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis. Journal of biomedical science. 2023 Aug; 30(1):62. doi: 10.1186/s12929-023-00957-9. [PMID: 37533081]
  • Liu Di, Zhang Yingqi, Y U Tianyuan, Liu Zhifeng, Jiao Yi, Wang Hourong, X U Yajing, Guan Qian, Chen Lulu, H U Hui. Protective mechanisms of Tuina therapy against lipopolysaccharide-induced fever in young rabbits based on untargeted metabolomics analysis. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2023 Aug; 43(4):725-733. doi: 10.19852/j.cnki.jtcm.2023.04.007. [PMID: 37454257]
  • Weixuan Wang, Mingjie Liang, Lexun Wang, Weijian Bei, Jiao Guo. 15-Hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates hepatic abnormal lipid metabolism, ER stress, and inflammation through PGE2/EP4 in T2DM mice. Bioorganic chemistry. 2023 08; 137(?):106646. doi: 10.1016/j.bioorg.2023.106646. [PMID: 37285764]
  • Jingwen Gan, Shi-Yang Zhu, Xiao Ma, Xue-Song Ding, Yan Deng, Yanfang Wang, Ai-Jun Sun. The effect of Ding-kun-dan comparing with Marvelon on primary dysmenorrhea: A prospective, double-blind, multicenter, randomized controlled trial. Journal of ethnopharmacology. 2023 Jul; ?(?):116975. doi: 10.1016/j.jep.2023.116975. [PMID: 37517569]
  • Ari Sérgio de O Lemos, Lara M Campos, Juliana da T Granato, Priscila V Z C Goliatt, Paula R B Dib, Eugenio D Hottz, Nícolas Glanzmann, Laíris C Campos, Heloisa D S Bizarro, Luciana M Chedier, Elaine S Coimbra, Rodrigo L Fabri. Mitracarpus frigidus reduces lipid metabolism and PGE2 levels in inflammatory cells. The Journal of pharmacy and pharmacology. 2023 Jul; ?(?):. doi: 10.1093/jpp/rgad069. [PMID: 37487573]
  • Piotr Kaczynski, Ewelina Goryszewska-Szczurek, Monika Baryla, Agnieszka Waclawik. Novel insights into conceptus-maternal signaling during pregnancy establishment in pigs. Molecular reproduction and development. 2023 07; 90(7):658-672. doi: 10.1002/mrd.23567. [PMID: 35385215]
  • Maggie E Phillips, Oluwabori Adekanye, Abdolsamad Borazjani, J Allen Crow, Matthew K Ross. CES1 Releases Oxylipins from Oxidized Triacylglycerol (oxTAG) and Regulates Macrophage oxTAG/TAG Accumulation and PGE2/IL-1β Production. ACS chemical biology. 2023 Jun; ?(?):. doi: 10.1021/acschembio.3c00194. [PMID: 37348046]
  • Wenbo Xie, Lu An, Zhaoyang Liu, Xindi Wang, Xueqi Fu, Junfeng Ma. Therapeutic Effect of Polaprezinc on Reflux Esophagitis in the Rat Model. Digestive diseases and sciences. 2023 Jun; ?(?):. doi: 10.1007/s10620-023-07990-6. [PMID: 37335414]
  • Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi, Yuri Aono, Tadashi Saigusa, Yasuhiro Kosuge. Update on the pathological roles of prostaglandin E2 in neurodegeneration in amyotrophic lateral sclerosis. Translational neurodegeneration. 2023 Jun; 12(1):32. doi: 10.1186/s40035-023-00366-w. [PMID: 37337289]
  • Mingjie Liang, Lexun Wang, Weixuan Wang. The 15-hydroxyprostaglandin dehydrogenase inhibitor SW033291 ameliorates abnormal hepatic glucose metabolism through PGE2-EP4 receptor-AKT signaling in a type 2 diabetes mellitus mouse model. Cellular signalling. 2023 May; 108(?):110707. doi: 10.1016/j.cellsig.2023.110707. [PMID: 37164143]
  • Grace Adebayo-Gege, Zainab Shehu Uthman, Moses Dele Adams, Tarfa Florence, Danazumi Umar Haruna, Ngabea Murtala Audu, Hamidu Jabba Lawan, Ozegbe Queen, Onwuchekwa Chinedu, Ajibola Meraiyebu, Ojo Kafaru. Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 May; 161(?):114531. doi: 10.1016/j.biopha.2023.114531. [PMID: 36934555]
  • Jianyang Liu, Bing Peng, Julia Steinmetz-Späh, Helena Idborg, Marina Korotkova, Per-Johan Jakobsson. Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro. Prostaglandins & other lipid mediators. 2023 Apr; 167(?):106738. doi: 10.1016/j.prostaglandins.2023.106738. [PMID: 37094780]
  • Jun Yang, Juan Wang, Yu Zhang, Wenjing Huang, Shaoqing Zhang, Peihao Yin, Wenfu Tan. c-Jun phosphorylated by JNK is required for protecting Gli2 from proteasomal-ubiquitin degradation by PGE2-JNK signaling axis. Biochimica et biophysica acta. Molecular cell research. 2023 03; 1870(3):119418. doi: 10.1016/j.bbamcr.2022.119418. [PMID: 36581088]
  • Momita Rani Baro, Manas Das, Anuradha Kalita, Bhabajyoti Das, Kishore Sarma. Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation. Journal of ethnopharmacology. 2023 Mar; 303(?):116021. doi: 10.1016/j.jep.2022.116021. [PMID: 36516907]
  • Juliann B Burkett, Amanda C Doran, Maureen Gannon. Harnessing prostaglandin E2 signaling to ameliorate autoimmunity. Trends in immunology. 2023 Mar; 44(3):162-171. doi: 10.1016/j.it.2023.01.004. [PMID: 36707339]
  • Miyu Komatsu, Takeshi Funakoshi, Toshihiko Aki, Kana Unuma, Koichi Uemura. Aristolochic acid induces an inflammatory response with prostaglandin E2 production and apoptosis in NRK-52E proximal tubular cells. Toxicology letters. 2023 Feb; ?(?):. doi: 10.1016/j.toxlet.2023.02.009. [PMID: 36863539]
  • Harsharan Singh Bhatia, Matthias Apweiler, Lu Sun, Julian Baron, Ashwini Tirkey, Bernd L Fiebich. Licochalcone A Inhibits Prostaglandin E2 by Targeting the MAPK Pathway in LPS Activated Primary Microglia. Molecules (Basel, Switzerland). 2023 Feb; 28(4):. doi: 10.3390/molecules28041927. [PMID: 36838914]
  • Abdul Hasan, Shree Devi Ms, Geetika Sharma, Vimal Narayanan, P Sathiyarajeswaran, S Vinayak, Sujatha Sunil. Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under invitro conditions. Journal of ethnopharmacology. 2023 Feb; 302(Pt A):115762. doi: 10.1016/j.jep.2022.115762. [PMID: 36181982]
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