7-Methoxy-1-methyl-4,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indole (BioDeep_00000185383)

   

human metabolite blood metabolite


代谢物信息卡片


7-Methoxy-1-methyl-4,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indole

化学式: C13H16N2O (216.12625659999998)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C2C(CC=N1)C3=C(N2)C=C(C=C3)OC
InChI: InChI=1S/C13H16N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,6-8,11,13,15H,5H2,1-2H3

描述信息

同义名列表

2 个代谢物同义名

7-Methoxy-1-methyl-4,4a,9,9a-tetrahydro-1H-pyrido[3,4-b]indole; 7-methoxy-1-methyl-1H,4H,4aH,9H,9aH-pyrido[3,4-b]indole



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jordi Riba, Ethan H McIlhenny, Marta Valle, José Carlos Bouso, Steven A Barker. Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca. Drug testing and analysis. 2012 Jul; 4(7-8):610-6. doi: 10.1002/dta.1344. [PMID: 22514127]
  • José Carlos Bouso, Débora González, Sabela Fondevila, Marta Cutchet, Xavier Fernández, Paulo César Ribeiro Barbosa, Miguel Ángel Alcázar-Córcoles, Wladimyr Sena Araújo, Manel J Barbanoj, Josep Maria Fábregas, Jordi Riba. Personality, psychopathology, life attitudes and neuropsychological performance among ritual users of Ayahuasca: a longitudinal study. PloS one. 2012; 7(8):e42421. doi: 10.1371/journal.pone.0042421. [PMID: 22905130]
  • Ethan H McIlhenny, Jordi Riba, Manel J Barbanoj, Rick Strassman, Steven A Barker. Methodology for and the determination of the major constituents and metabolites of the Amazonian botanical medicine ayahuasca in human urine. Biomedical chromatography : BMC. 2011 Sep; 25(9):970-84. doi: 10.1002/bmc.1551. [PMID: 21058415]
  • Nahida Tabassum, Feroz Ahmad. Role of natural herbs in the treatment of hypertension. Pharmacognosy reviews. 2011 Jan; 5(9):30-40. doi: 10.4103/0973-7847.79097. [PMID: 22096316]
  • Yan-Hong Wang, Volodymyr Samoylenko, Babu L Tekwani, Ikhlas A Khan, Loren S Miller, Narayan D Chaurasiya, Md Mostafizur Rahman, Lalit M Tripathi, Shabana I Khan, Vaishali C Joshi, Frank T Wigger, Ilias Muhammad. Composition, standardization and chemical profiling of Banisteriopsis caapi, a plant for the treatment of neurodegenerative disorders relevant to Parkinson's disease. Journal of ethnopharmacology. 2010 Apr; 128(3):662-71. doi: 10.1016/j.jep.2010.02.013. [PMID: 20219660]
  • T Herraiz, D González, C Ancín-Azpilicueta, V J Arán, H Guillén. beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2010 Mar; 48(3):839-45. doi: 10.1016/j.fct.2009.12.019. [PMID: 20036304]
  • Volodymyr Samoylenko, Md Mostafizur Rahman, Babu L Tekwani, Lalit M Tripathi, Yan-Hong Wang, Shabana I Khan, Ikhlas A Khan, Loren S Miller, Vaishali C Joshi, Ilias Muhammad. Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease. Journal of ethnopharmacology. 2010 Feb; 127(2):357-67. doi: 10.1016/j.jep.2009.10.030. [PMID: 19879939]
  • Ana Paula Salum Pires, Carolina Dizioli Rodrigues De Oliveira, Sidnei Moura, Felipe Augusto Dörr, Wagner Abreu E Silva, Mauricio Yonamine. Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage. Phytochemical analysis : PCA. 2009 Mar; 20(2):149-53. doi: 10.1002/pca.1110. [PMID: 19140116]
  • Giampietro Frison, Donata Favretto, Flavio Zancanaro, Giorgio Fazzin, Santo Davide Ferrara. A case of beta-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract. Forensic science international. 2008 Aug; 179(2-3):e37-43. doi: 10.1016/j.forsciint.2008.05.003. [PMID: 18603389]
  • R G Santos, J Landeira-Fernandez, R J Strassman, V Motta, A P M Cruz. Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members. Journal of ethnopharmacology. 2007 Jul; 112(3):507-13. doi: 10.1016/j.jep.2007.04.012. [PMID: 17532158]
  • J C Callaway, Glacus S Brito, Edison S Neves. Phytochemical analyses of Banisteriopsis caapi and Psychotria viridis. Journal of psychoactive drugs. 2005 Jun; 37(2):145-50. doi: 10.1080/02791072.2005.10399795. [PMID: 16149327]
  • J C Callaway. Various alkaloid profiles in decoctions of Banisteriopsis caapi. Journal of psychoactive drugs. 2005 Jun; 37(2):151-5. doi: 10.1080/02791072.2005.10399796. [PMID: 16149328]
  • Jordi Riba, Marta Valle, Gloria Urbano, Mercedes Yritia, Adelaida Morte, Manel J Barbanoj. Human pharmacology of ayahuasca: subjective and cardiovascular effects, monoamine metabolite excretion, and pharmacokinetics. The Journal of pharmacology and experimental therapeutics. 2003 Jul; 306(1):73-83. doi: 10.1124/jpet.103.049882. [PMID: 12660312]
  • Mercedes Yritia, Jordi Riba, Jordi Ortuño, Ariel Ramirez, Araceli Castillo, Yolanda Alfaro, Rafael de la Torre, Manel J Barbanoj. Determination of N,N-dimethyltryptamine and beta-carboline alkaloids in human plasma following oral administration of Ayahuasca. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Nov; 779(2):271-81. doi: 10.1016/s1570-0232(02)00397-5. [PMID: 12361741]