Phosphono 2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl hydrogen phosphate (BioDeep_00000185377)
human metabolite blood metabolite
代谢物信息卡片
({hydroxy[(2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl)oxy]phosphoryl}oxy)phosphonic acid
化学式: C20H36O7P2 (450.1936166)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: CC(C)=CCCC(C)=CCC(OP(O)(=O)OP(O)(O)=O)C=C(C)CCC=C(C)C
InChI: InChI=1S/C20H36O7P2/c1-16(2)9-7-11-18(5)13-14-20(15-19(6)12-8-10-17(3)4)26-29(24,25)27-28(21,22)23/h9-10,13,15,20H,7-8,11-12,14H2,1-6H3,(H,24,25)(H2,21,22,23)
描述信息
同义名列表
5 个代谢物同义名
({hydroxy[(2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl)oxy]phosphoryl}oxy)phosphonic acid; [hydroxy((2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl)oxy)phosphoryl]oxyphosphonic acid; ({hydroxy[(2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl)oxy]phosphoryl}oxy)phosphonate; Phosphono 2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl hydrogen phosphoric acid; Phosphono 2,6,11,15-tetramethylhexadeca-2,6,10,14-tetraen-8-yl hydrogen phosphate
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhubo Dai, Yi Liu, Luqi Huang, Xueli Zhang. Production of miltiradiene by metabolically engineered Saccharomyces cerevisiae.
Biotechnology and bioengineering.
2012 Nov; 109(11):2845-53. doi:
10.1002/bit.24547. [PMID: 22566191] - Janine Kah, Andrea Wüstenberg, Amelie Dorothea Keller, Hüseyin Sirma, Roberta Montalbano, Matthias Ocker, Tassilo Volz, Maura Dandri, Gisa Tiegs, Gabriele Sass. Selective induction of apoptosis by HMG-CoA reductase inhibitors in hepatoma cells and dependence on p53 expression.
Oncology reports.
2012 Sep; 28(3):1077-83. doi:
10.3892/or.2012.1860. [PMID: 22710979] - Bianca Dibari, Florent Murat, Audrey Chosson, Véronique Gautier, Charles Poncet, Philippe Lecomte, Ingrid Mercier, Hélène Bergès, Caroline Pont, Antonio Blanco, Jérôme Salse. Deciphering the genomic structure, function and evolution of carotenogenesis related phytoene synthases in grasses.
BMC genomics.
2012 Jun; 13(?):221. doi:
10.1186/1471-2164-13-221. [PMID: 22672222] - Jin-Hee Kim, Kwang-Il Lee, Yung-Jin Chang, Soo-Un Kim. Developmental pattern of Ginkgo biloba levopimaradiene synthase (GbLPS) as probed by promoter analysis in Arabidopsis thaliana.
Plant cell reports.
2012 Jun; 31(6):1119-27. doi:
10.1007/s00299-012-1232-1. [PMID: 22311479] - Liang Sun, Bing Yuan, Mei Zhang, Ling Wang, Mengmeng Cui, Qi Wang, Ping Leng. Fruit-specific RNAi-mediated suppression of SlNCED1 increases both lycopene and β-carotene contents in tomato fruit.
Journal of experimental botany.
2012 May; 63(8):3097-108. doi:
10.1093/jxb/ers026. [PMID: 22345638] - Danilo Aros, Veronica Gonzalez, Rudolf K Allemann, Carsten T Müller, Carlo Rosati, Hilary J Rogers. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers.
Journal of experimental botany.
2012 Apr; 63(7):2739-52. doi:
10.1093/jxb/err456. [PMID: 22268153] - Yimian Ma, Lichai Yuan, Bin Wu, Xian'en Li, Shilin Chen, Shanfa Lu. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza.
Journal of experimental botany.
2012 Apr; 63(7):2809-23. doi:
10.1093/jxb/err466. [PMID: 22291132] - Jun-Ling Li, Qian-Qian Chen, Qiu-Ping Jin, Juan Gao, Pei-Ji Zhao, Shan Lu, Ying Zeng. IeCPS2 is potentially involved in the biosynthesis of pharmacologically active Isodon diterpenoids rather than gibberellin.
Phytochemistry.
2012 Apr; 76(?):32-9. doi:
10.1016/j.phytochem.2011.12.021. [PMID: 22284743] - Dimas M Ribeiro, Wagner L Araújo, Alisdair R Fernie, Jos H M Schippers, Bernd Mueller-Roeber. Translatome and metabolome effects triggered by gibberellins during rosette growth in Arabidopsis.
Journal of experimental botany.
2012 Apr; 63(7):2769-86. doi:
10.1093/jxb/err463. [PMID: 22291129] - Sol A Green, Xiuyin Chen, Niels J Nieuwenhuizen, Adam J Matich, Mindy Y Wang, Barry J Bunn, Yar-Khing Yauk, Ross G Atkinson. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis).
Journal of experimental botany.
2012 Mar; 63(5):1951-67. doi:
10.1093/jxb/err393. [PMID: 22162874] - Insaf Thabet, Grégory Guirimand, Anthony Guihur, Arnaud Lanoue, Vincent Courdavault, Nicolas Papon, Sadok Bouzid, Nathalie Giglioli-Guivarc'h, Andrew J Simkin, Marc Clastre. Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus.
Molecular biology reports.
2012 Mar; 39(3):3235-43. doi:
10.1007/s11033-011-1091-9. [PMID: 21706164] - Raimund Nagel, Jonathan Gershenzon, Axel Schmidt. Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry.
Analytical biochemistry.
2012 Mar; 422(1):33-8. doi:
10.1016/j.ab.2011.12.037. [PMID: 22266300] - Philipp Zerbe, Angela Chiang, Jörg Bohlmann. Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism.
Phytochemistry.
2012 Feb; 74(?):30-9. doi:
10.1016/j.phytochem.2011.11.004. [PMID: 22177479] - Bin Wu, Ying Li, Haixia Yan, Yimian Ma, Hongmei Luo, Lichai Yuan, Shilin Chen, Shanfa Lu. Comprehensive transcriptome analysis reveals novel genes involved in cardiac glycoside biosynthesis and mlncRNAs associated with secondary metabolism and stress response in Digitalis purpurea.
BMC genomics.
2012 Jan; 13(?):15. doi:
10.1186/1471-2164-13-15. [PMID: 22233149] - Tapan Kumar Mohanta, Andrea Occhipinti, Simon Atsbaha Zebelo, Maria Foti, Judith Fliegmann, Simone Bossi, Massimo E Maffei, Cinzia M Bertea. Ginkgo biloba responds to herbivory by activating early signaling and direct defenses.
PloS one.
2012; 7(3):e32822. doi:
10.1371/journal.pone.0032822. [PMID: 22448229] - Tahira Fatima, Crystal L Snyder, William R Schroeder, Dustin Cram, Raju Datla, David Wishart, Randall J Weselake, Priti Krishna. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed.
PloS one.
2012; 7(4):e34099. doi:
10.1371/journal.pone.0034099. [PMID: 22558083] - Xiumin Fu, Wenbin Kong, Gang Peng, Jingyi Zhou, Muhammad Azam, Changjie Xu, Don Grierson, Kunsong Chen. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits.
Journal of experimental botany.
2012 Jan; 63(1):341-54. doi:
10.1093/jxb/err284. [PMID: 21994170] - Takeru Yokoi, Keisuke Isobe, Tohru Yoshimura, Hisashi Hemmi. Archaeal phospholipid biosynthetic pathway reconstructed in Escherichia coli.
Archaea (Vancouver, B.C.).
2012; 2012(?):438931. doi:
10.1155/2012/438931. [PMID: 22645416] - Eleanore T Wurtzel, Abby Cuttriss, Ratnakar Vallabhaneni. Maize provitamin a carotenoids, current resources, and future metabolic engineering challenges.
Frontiers in plant science.
2012; 3(?):29. doi:
10.3389/fpls.2012.00029. [PMID: 22645578] - Lancui Zhang, Gang Ma, Masaya Kato, Kazuki Yamawaki, Toshihiko Takagi, Yoshikazu Kiriiwa, Yoshinori Ikoma, Hikaru Matsumoto, Terutaka Yoshioka, Hirohisa Nesumi. Regulation of carotenoid accumulation and the expression of carotenoid metabolic genes in citrus juice sacs in vitro.
Journal of experimental botany.
2012 Jan; 63(2):871-86. doi:
10.1093/jxb/err318. [PMID: 21994171] - Qing Li, Xiaohong Yang, Shutu Xu, Ye Cai, Dalong Zhang, Yingjia Han, Lin Li, Zuxin Zhang, Shibin Gao, Jiansheng Li, Jianbing Yan. Genome-wide association studies identified three independent polymorphisms associated with α-tocopherol content in maize kernels.
PloS one.
2012; 7(5):e36807. doi:
10.1371/journal.pone.0036807. [PMID: 22615816] - Hongmei Luo, Chao Sun, Yongzhen Sun, Qiong Wu, Ying Li, Jingyuan Song, Yunyun Niu, Xianglin Cheng, Hongxi Xu, Chuyuan Li, Juyan Liu, André Steinmetz, Shilin Chen. Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers.
BMC genomics.
2011 Dec; 12 Suppl 5(?):S5. doi:
10.1186/1471-2164-12-s5-s5. [PMID: 22369100] - Yoshinori Sugai, Yohei Ueno, Ken-ichiro Hayashi, Shingo Oogami, Tomonobu Toyomasu, Sadamu Matsumoto, Masahiro Natsume, Hiroshi Nozaki, Hiroshi Kawaide. Enzymatic (13)C labeling and multidimensional NMR analysis of miltiradiene synthesized by bifunctional diterpene cyclase in Selaginella moellendorffii.
The Journal of biological chemistry.
2011 Dec; 286(50):42840-7. doi:
10.1074/jbc.m111.302703. [PMID: 22027823] - Roberto A Barrero, Brett Chapman, Yanfang Yang, Paula Moolhuijzen, Gabriel Keeble-Gagnère, Nan Zhang, Qi Tang, Matthew I Bellgard, Deyou Qiu. De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes.
BMC genomics.
2011 Dec; 12(?):600. doi:
10.1186/1471-2164-12-600. [PMID: 22151917] - Axel Schmidt, Raimund Nagel, Trygve Krekling, Erik Christiansen, Jonathan Gershenzon, Paal Krokene. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies).
Plant molecular biology.
2011 Dec; 77(6):577-90. doi:
10.1007/s11103-011-9832-7. [PMID: 22002747] - Nelson L Brock, Bettina Tudzynski, Jeroen S Dickschat. Biosynthesis of sesqui- and diterpenes by the gibberellin producer Fusarium fujikuroi.
Chembiochem : a European journal of chemical biology.
2011 Nov; 12(17):2667-76. doi:
10.1002/cbic.201100516. [PMID: 21990128] - Yunliu Zeng, Zhiyong Pan, Yuduan Ding, Andan Zhu, Hongbo Cao, Qiang Xu, Xiuxin Deng. A proteomic analysis of the chromoplasts isolated from sweet orange fruits [Citrus sinensis (L.) Osbeck].
Journal of experimental botany.
2011 Nov; 62(15):5297-309. doi:
10.1093/jxb/err140. [PMID: 21841170] - Christopher I Keeling, Lina L Madilao, Philipp Zerbe, Harpreet K Dullat, Jörg Bohlmann. The primary diterpene synthase products of Picea abies levopimaradiene/abietadiene synthase (PaLAS) are epimers of a thermally unstable diterpenol.
The Journal of biological chemistry.
2011 Jun; 286(24):21145-53. doi:
10.1074/jbc.m111.245951. [PMID: 21518766] - Yu-Juan Zhong, Jun-Chao Huang, Jin Liu, Yin Li, Yue Jiang, Zeng-Fu Xu, Gerhard Sandmann, Feng Chen. Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis.
Journal of experimental botany.
2011 Jun; 62(10):3659-69. doi:
10.1093/jxb/err070. [PMID: 21398427] - Mustafa Köksal, Huayou Hu, Robert M Coates, Reuben J Peters, David W Christianson. Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase.
Nature chemical biology.
2011 May; 7(7):431-3. doi:
10.1038/nchembio.578. [PMID: 21602811] - Stuart Meier, Oren Tzfadia, Ratnakar Vallabhaneni, Chris Gehring, Eleanore T Wurtzel. A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana.
BMC systems biology.
2011 May; 5(?):77. doi:
10.1186/1752-0509-5-77. [PMID: 21595952] - Christopher I Keeling, Sabrina Weisshaar, Steven G Ralph, Sharon Jancsik, Britta Hamberger, Harpreet K Dullat, Jörg Bohlmann. Transcriptome mining, functional characterization, and phylogeny of a large terpene synthase gene family in spruce (Picea spp.).
BMC plant biology.
2011 Mar; 11(?):43. doi:
10.1186/1471-2229-11-43. [PMID: 21385377] - I L M H Aye, B J Waddell, P J Mark, J A Keelan. Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.
Placenta.
2011 Feb; 32(2):183-91. doi:
10.1016/j.placenta.2010.12.007. [PMID: 21208656] - Hiroshi Kawaide, Ken-ichiro Hayashi, Ryo Kawanabe, Yuka Sakigi, Akihiko Matsuo, Masahiro Natsume, Hiroshi Nozaki. Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens.
The FEBS journal.
2011 Jan; 278(1):123-33. doi:
10.1111/j.1742-4658.2010.07938.x. [PMID: 21122070] - Wenyu Yang, Rebecca E Cahoon, Sarah C Hunter, Chunyu Zhang, Jixiang Han, Trissa Borgschulte, Edgar B Cahoon. Vitamin E biosynthesis: functional characterization of the monocot homogentisate geranylgeranyl transferase.
The Plant journal : for cell and molecular biology.
2011 Jan; 65(2):206-17. doi:
10.1111/j.1365-313x.2010.04417.x. [PMID: 21223386] - Kazunori Okada. The biosynthesis of isoprenoids and the mechanisms regulating it in plants.
Bioscience, biotechnology, and biochemistry.
2011; 75(7):1219-25. doi:
10.1271/bbb.110228. [PMID: 21737944] - Kristina L Ford, Andrew Cassin, Antony Bacic. Quantitative proteomic analysis of wheat cultivars with differing drought stress tolerance.
Frontiers in plant science.
2011; 2(?):44. doi:
10.3389/fpls.2011.00044. [PMID: 22639595] - Da Cheng Hao, GuangBo Ge, PeiGen Xiao, YanYan Zhang, Ling Yang. The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing.
PloS one.
2011; 6(6):e21220. doi:
10.1371/journal.pone.0021220. [PMID: 21731678] - Sang-Gyu Kim, Felipe Yon, Emmanuel Gaquerel, Jyotasana Gulati, Ian T Baldwin. Tissue specific diurnal rhythms of metabolites and their regulation during herbivore attack in a native tobacco, Nicotiana attenuata.
PloS one.
2011; 6(10):e26214. doi:
10.1371/journal.pone.0026214. [PMID: 22028833] - Jordi Bou-Torrent, Jaime F Martínez-García, José Luis García-Martínez, Salomé Prat. Gibberellin A1 metabolism contributes to the control of photoperiod-mediated tuberization in potato.
PloS one.
2011; 6(9):e24458. doi:
10.1371/journal.pone.0024458. [PMID: 21961036] - Linkun Wu, Haibin Wang, Zhixing Zhang, Rui Lin, Zhongyi Zhang, Wenxiong Lin. Comparative metaproteomic analysis on consecutively Rehmannia glutinosa-monocultured rhizosphere soil.
PloS one.
2011; 6(5):e20611. doi:
10.1371/journal.pone.0020611. [PMID: 21655235] - Malgorzata A Domagalska, Elzbieta Sarnowska, Ferenc Nagy, Seth J Davis. Genetic analyses of interactions among gibberellin, abscisic acid, and brassinosteroids in the control of flowering time in Arabidopsis thaliana.
PloS one.
2010 Nov; 5(11):e14012. doi:
10.1371/journal.pone.0014012. [PMID: 21103336] - Jayaram Bhandari, A Heather Fitzpatrick, Dring N Crowell. Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis.
Plant physiology.
2010 Nov; 154(3):1116-27. doi:
10.1104/pp.110.157784. [PMID: 20807998] - Hao Du, Nili Wang, Fei Cui, Xianghua Li, Jinghua Xiao, Lizhong Xiong. Characterization of the beta-carotene hydroxylase gene DSM2 conferring drought and oxidative stress resistance by increasing xanthophylls and abscisic acid synthesis in rice.
Plant physiology.
2010 Nov; 154(3):1304-18. doi:
10.1104/pp.110.163741. [PMID: 20852032] - Li Liu, Changhua Hu. [Advance in fungal diterpene cyclase--a review].
Wei sheng wu xue bao = Acta microbiologica Sinica.
2010 Nov; 50(11):1438-45. doi:
". [PMID: 21268887] - Gianfranco Diretto, Salim Al-Babili, Raffaela Tavazza, Federico Scossa, Velia Papacchioli, Melania Migliore, Peter Beyer, Giovanni Giuliano. Transcriptional-metabolic networks in beta-carotene-enriched potato tubers: the long and winding road to the Golden phenotype.
Plant physiology.
2010 Oct; 154(2):899-912. doi:
10.1104/pp.110.159368. [PMID: 20671108] - Yechun Wang, Zhiqi Miao, Kexuan Tang. Molecular cloning and functional expression analysis of a new gene encoding geranylgeranyl diphosphate synthase from hazel (Corylus avellana L. Gasaway).
Molecular biology reports.
2010 Oct; 37(7):3439-44. doi:
10.1007/s11033-009-9935-2. [PMID: 20012370] - Ping Lan, Wenfeng Li, Huizhong Wang, Wujun Ma. Characterization, sub-cellular localization and expression profiling of the isoprenylcysteine methylesterase gene family in Arabidopsis thaliana.
BMC plant biology.
2010 Sep; 10(?):212. doi:
10.1186/1471-2229-10-212. [PMID: 20868530] - Hongmei Luo, Ying Li, Chao Sun, Qiong Wu, Jingyuan Song, Yongzhen Sun, André Steinmetz, Shilin Chen. Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation.
BMC plant biology.
2010 Sep; 10(?):209. doi:
10.1186/1471-2229-10-209. [PMID: 20854695] - Vasiliki Falara, Eran Pichersky, Angelos K Kanellis. A copal-8-ol diphosphate synthase from the angiosperm Cistus creticus subsp. creticus is a putative key enzyme for the formation of pharmacologically active, oxygen-containing labdane-type diterpenes.
Plant physiology.
2010 Sep; 154(1):301-10. doi:
10.1104/pp.110.159566. [PMID: 20595348] - Mitsuko Kishi-Kaboshi, Kazunori Okada, Leona Kurimoto, Shinya Murakami, Toshiaki Umezawa, Naoto Shibuya, Hisakazu Yamane, Akio Miyao, Hiroshi Takatsuji, Akira Takahashi, Hirohiko Hirochika. A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis.
The Plant journal : for cell and molecular biology.
2010 Aug; 63(4):599-612. doi:
10.1111/j.1365-313x.2010.04264.x. [PMID: 20525005] - Ken-ichiro Hayashi, Keisuke Horie, Yuji Hiwatashi, Hiroshi Kawaide, Shinjiro Yamaguchi, Atsushi Hanada, Tamotsu Nakashima, Masatoshi Nakajima, Lewis N Mander, Hisakazu Yamane, Mitsuyasu Hasebe, Hiroshi Nozaki. Endogenous diterpenes derived from ent-kaurene, a common gibberellin precursor, regulate protonema differentiation of the moss Physcomitrella patens.
Plant physiology.
2010 Jul; 153(3):1085-97. doi:
10.1104/pp.110.157909. [PMID: 20488896] - Sumitra Miriyala, Thangaiah Subramanian, Manikandan Panchatcharam, Hongmei Ren, Mark I McDermott, Manjula Sunkara, Tracy Drennan, Susan S Smyth, H Peter Spielmann, Andrew J Morris. Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells.
The Journal of biological chemistry.
2010 Apr; 285(18):13918-29. doi:
10.1074/jbc.m109.083931. [PMID: 20110354] - Christopher I Keeling, Harpreet K Dullat, Mack Yuen, Steven G Ralph, Sharon Jancsik, Jörg Bohlmann. Identification and functional characterization of monofunctional ent-copalyl diphosphate and ent-kaurene synthases in white spruce reveal different patterns for diterpene synthase evolution for primary and secondary metabolism in gymnosperms.
Plant physiology.
2010 Mar; 152(3):1197-208. doi:
10.1104/pp.109.151456. [PMID: 20044448] - Daniel J Antoine, Abhishek Srivastava, Munir Pirmohamed, B Kevin Park. Statins inhibit aminoglycoside accumulation and cytotoxicity to renal proximal tubule cells.
Biochemical pharmacology.
2010 Feb; 79(4):647-54. doi:
10.1016/j.bcp.2009.09.021. [PMID: 19782050] - Axel Schmidt, Betty Wächtler, Ulrike Temp, Trygve Krekling, Armand Séguin, Jonathan Gershenzon. A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies.
Plant physiology.
2010 Feb; 152(2):639-55. doi:
10.1104/pp.109.144691. [PMID: 19939949] - Tao-Hsin Chang, Fu-Lien Hsieh, Tzu-Ping Ko, Kuo-Hsun Teng, Po-Huang Liang, Andrew H-J Wang. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation.
The Plant cell.
2010 Feb; 22(2):454-67. doi:
10.1105/tpc.109.071738. [PMID: 20139160] - Xiangjun Zhou, Peter Cooke, Li Li. Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling development.
Journal of experimental botany.
2010; 61(2):357-67. doi:
10.1093/jxb/erp308. [PMID: 19939886] - Jelena Klawitter, Touraj Shokati, Vanessa Moll, Uwe Christians, Jost Klawitter. Effects of lovastatin on breast cancer cells: a proteo-metabonomic study.
Breast cancer research : BCR.
2010; 12(2):R16. doi:
10.1186/bcr2485. [PMID: 20205716] - Nemesio Villa-Ruano, Martha Guadalupe Betancourt-Jiménez, Edmundo Lozoya-Gloria. Biosynthesis of uterotonic diterpenes from Montanoa tomentosa (zoapatle).
Journal of plant physiology.
2009 Dec; 166(18):1961-7. doi:
10.1016/j.jplph.2009.06.004. [PMID: 19581023] - Sophie Vandermoten, Eric Haubruge, Michel Cusson. New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition.
Cellular and molecular life sciences : CMLS.
2009 Dec; 66(23):3685-95. doi:
10.1007/s00018-009-0100-9. [PMID: 19633972] - Qiang Xu, Keqin Yu, Andan Zhu, Junli Ye, Qing Liu, Jianchen Zhang, Xiuxin Deng. Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant.
BMC genomics.
2009 Nov; 10(?):540. doi:
10.1186/1471-2164-10-540. [PMID: 19922663] - Michel Havaux, Brigitte Ksas, Agnieszka Szewczyk, Dominique Rumeau, Fabrice Franck, Stefano Caffarri, Christian Triantaphylidès. Vitamin B6 deficient plants display increased sensitivity to high light and photo-oxidative stress.
BMC plant biology.
2009 Nov; 9(?):130. doi:
10.1186/1471-2229-9-130. [PMID: 19903353] - Nikolai Shalygo, Olaf Czarnecki, Enrico Peter, Bernhard Grimm. Expression of chlorophyll synthase is also involved in feedback-control of chlorophyll biosynthesis.
Plant molecular biology.
2009 Nov; 71(4-5):425-36. doi:
10.1007/s11103-009-9532-8. [PMID: 19680747] - Marcelo Bertalan, Rodolpho Albano, Vânia de Pádua, Luc Rouws, Cristian Rojas, Adriana Hemerly, Kátia Teixeira, Stefan Schwab, Jean Araujo, André Oliveira, Leonardo França, Viviane Magalhães, Sylvia Alquéres, Alexander Cardoso, Wellington Almeida, Marcio Martins Loureiro, Eduardo Nogueira, Daniela Cidade, Denise Oliveira, Tatiana Simão, Jacyara Macedo, Ana Valadão, Marcela Dreschsel, Flávia Freitas, Marcia Vidal, Helma Guedes, Elisete Rodrigues, Carlos Meneses, Paulo Brioso, Luciana Pozzer, Daniel Figueiredo, Helena Montano, Jadier Junior, Gonçalo de Souza Filho, Victor Martin Quintana Flores, Beatriz Ferreira, Alan Branco, Paula Gonzalez, Heloisa Guillobel, Melissa Lemos, Luiz Seibel, José Macedo, Marcio Alves-Ferreira, Gilberto Sachetto-Martins, Ana Coelho, Eidy Santos, Gilda Amaral, Anna Neves, Ana Beatriz Pacheco, Daniela Carvalho, Letícia Lery, Paulo Bisch, Shaila C Rössle, Turán Urményi, Alessandra Rael Pereira, Rosane Silva, Edson Rondinelli, Wanda von Krüger, Orlando Martins, José Ivo Baldani, Paulo C G Ferreira. Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5.
BMC genomics.
2009 Sep; 10(?):450. doi:
10.1186/1471-2164-10-450. [PMID: 19775431] - Dirk Maass, Jacobo Arango, Florian Wüst, Peter Beyer, Ralf Welsch. Carotenoid crystal formation in Arabidopsis and carrot roots caused by increased phytoene synthase protein levels.
PloS one.
2009 Jul; 4(7):e6373. doi:
10.1371/journal.pone.0006373. [PMID: 19636414] - Ratnakar Vallabhaneni, Eleanore T Wurtzel. Timing and biosynthetic potential for carotenoid accumulation in genetically diverse germplasm of maize.
Plant physiology.
2009 Jun; 150(2):562-72. doi:
10.1104/pp.109.137042. [PMID: 19346441] - Hong Yin, Alan Chu, Wei Li, Bin Wang, Fabiola Shelton, Francella Otero, Deborah G Nguyen, Jeremy S Caldwell, Yu Alice Chen. Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay.
The Journal of biological chemistry.
2009 May; 284(18):12328-38. doi:
10.1074/jbc.m806516200. [PMID: 19286662] - Henrik Toft Simonsen, Damian Paul Drew, Christina Lunde. Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates.
Perspectives in medicinal chemistry.
2009 Mar; 3(?):1-6. doi:
10.4137/pmc.s2220. [PMID: 19812738] - Joost Lücker, Mario Laszczak, Derek Smith, Steven T Lund. Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation.
BMC genomics.
2009 Jan; 10(?):50. doi:
10.1186/1471-2164-10-50. [PMID: 19171055] - Esther Gerber, Andréa Hemmerlin, Michael Hartmann, Dimitri Heintz, Marie-Andrée Hartmann, Jérôme Mutterer, Manuel Rodríguez-Concepción, Albert Boronat, Alain Van Dorsselaer, Michel Rohmer, Dring N Crowell, Thomas J Bach. The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells.
The Plant cell.
2009 Jan; 21(1):285-300. doi:
10.1105/tpc.108.063248. [PMID: 19136647] - Annamaria Morelli, Aravinda Krishnappa Chavalmane, Sandra Filippi, Benedetta Fibbi, Enrico Silvestrini, Erica Sarchielli, Xin-Hua Zhang, Linda Vignozzi, Gabriella Barbara Vannelli, Gianni Forti, Mario Maggi. Atorvastatin ameliorates sildenafil-induced penile erections in experimental diabetes by inhibiting diabetes-induced RhoA/Rho-kinase signaling hyperactivation.
The journal of sexual medicine.
2009 Jan; 6(1):91-106. doi:
10.1111/j.1743-6109.2008.01057.x. [PMID: 19170840] - Berta Alquézar, Lorenzo Zacarías, María J Rodrigo. Molecular and functional characterization of a novel chromoplast-specific lycopene beta-cyclase from Citrus and its relation to lycopene accumulation.
Journal of experimental botany.
2009; 60(6):1783-97. doi:
10.1093/jxb/erp048. [PMID: 19325166] - Jorge M C Mondego, Marcelo F Carazzolle, Gustavo G L Costa, Eduardo F Formighieri, Lucas P Parizzi, Johana Rincones, Carolina Cotomacci, Dirce M Carraro, Anderson F Cunha, Helaine Carrer, Ramon O Vidal, Raíssa C Estrela, Odalys García, Daniela P T Thomazella, Bruno V de Oliveira, Acássia Bl Pires, Maria Carolina S Rio, Marcos Renato R Araújo, Marcos H de Moraes, Luis A B Castro, Karina P Gramacho, Marilda S Gonçalves, José P Moura Neto, Aristóteles Góes Neto, Luciana V Barbosa, Mark J Guiltinan, Bryan A Bailey, Lyndel W Meinhardt, Julio Cm Cascardo, Gonçalo A G Pereira. A genome survey of Moniliophthora perniciosa gives new insights into Witches' Broom Disease of cacao.
BMC genomics.
2008 Nov; 9(?):548. doi:
10.1186/1471-2164-9-548. [PMID: 19019209] - Xavier Argout, Olivier Fouet, Patrick Wincker, Karina Gramacho, Thierry Legavre, Xavier Sabau, Ange Marie Risterucci, Corinne Da Silva, Julio Cascardo, Mathilde Allegre, David Kuhn, Joseph Verica, Brigitte Courtois, Gaston Loor, Regis Babin, Olivier Sounigo, Michel Ducamp, Mark J Guiltinan, Manuel Ruiz, Laurence Alemanno, Regina Machado, Wilberth Phillips, Ray Schnell, Martin Gilmour, Eric Rosenquist, David Butler, Siela Maximova, Claire Lanaud. Towards the understanding of the cocoa transcriptome: Production and analysis of an exhaustive dataset of ESTs of Theobroma cacao L. generated from various tissues and under various conditions.
BMC genomics.
2008 Oct; 9(?):512. doi:
10.1186/1471-2164-9-512. [PMID: 18973681] - Diana Köpke, Roland Schröder, Hanna M Fischer, Jonathan Gershenzon, Monika Hilker, Axel Schmidt. Does egg deposition by herbivorous pine sawflies affect transcription of sesquiterpene synthases in pine?.
Planta.
2008 Aug; 228(3):427-38. doi:
10.1007/s00425-008-0747-8. [PMID: 18493792] - Motoyoshi Noike, Takashi Katagiri, Toru Nakayama, Tanetoshi Koyama, Tokuzo Nishino, Hisashi Hemmi. The product chain length determination mechanism of type II geranylgeranyl diphosphate synthase requires subunit interaction.
The FEBS journal.
2008 Aug; 275(15):3921-33. doi:
10.1111/j.1742-4658.2008.06538.x. [PMID: 18616462] - Ross N Crowhurst, Andrew P Gleave, Elspeth A MacRae, Charles Ampomah-Dwamena, Ross G Atkinson, Lesley L Beuning, Sean M Bulley, David Chagne, Ken B Marsh, Adam J Matich, Mirco Montefiori, Richard D Newcomb, Robert J Schaffer, Björn Usadel, Andrew C Allan, Helen L Boldingh, Judith H Bowen, Marcus W Davy, Rheinhart Eckloff, A Ross Ferguson, Lena G Fraser, Emma Gera, Roger P Hellens, Bart J Janssen, Karin Klages, Kim R Lo, Robin M MacDiarmid, Bhawana Nain, Mark A McNeilage, Maysoon Rassam, Annette C Richardson, Erik Ha Rikkerink, Gavin S Ross, Roswitha Schröder, Kimberley C Snowden, Edwige J F Souleyre, Matt D Templeton, Eric F Walton, Daisy Wang, Mindy Y Wang, Yanming Y Wang, Marion Wood, Rongmei Wu, Yar-Khing Yauk, William A Laing. Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.
BMC genomics.
2008 Jul; 9(?):351. doi:
10.1186/1471-2164-9-351. [PMID: 18655731] - Huaxiang Tong, Andrew J Wiemer, Jeffrey D Neighbors, Raymond J Hohl. Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue.
Analytical biochemistry.
2008 Jul; 378(2):138-43. doi:
10.1016/j.ab.2008.04.021. [PMID: 18457649] - Tomonobu Toyomasu. Recent advances regarding diterpene cyclase genes in higher plants and fungi.
Bioscience, biotechnology, and biochemistry.
2008 May; 72(5):1168-75. doi:
10.1271/bbb.80044. [PMID: 18460786] - Frances M Dupont. Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics.
BMC plant biology.
2008 Apr; 8(?):39. doi:
10.1186/1471-2229-8-39. [PMID: 18419817] - Marco Herde, Katrin Gärtner, Tobias G Köllner, Benjamin Fode, Wilhelm Boland, Jonathan Gershenzon, Christiane Gatz, Dorothea Tholl. Identification and regulation of TPS04/GES, an Arabidopsis geranyllinalool synthase catalyzing the first step in the formation of the insect-induced volatile C16-homoterpene TMTT.
The Plant cell.
2008 Apr; 20(4):1152-68. doi:
10.1105/tpc.106.049478. [PMID: 18398052] - Jun Fang, Chenglin Chai, Qian Qian, Chunlai Li, Jiuyou Tang, Lei Sun, Zejun Huang, Xiaoli Guo, Changhui Sun, Min Liu, Yan Zhang, Qingtao Lu, Yiqin Wang, Congming Lu, Bin Han, Fan Chen, Zhukuan Cheng, Chengcai Chu. Mutations of genes in synthesis of the carotenoid precursors of ABA lead to pre-harvest sprouting and photo-oxidation in rice.
The Plant journal : for cell and molecular biology.
2008 Apr; 54(2):177-89. doi:
10.1111/j.1365-313x.2008.03411.x. [PMID: 18208525] - Arto J Soitamo, Mirva Piippo, Yagut Allahverdiyeva, Natalia Battchikova, Eva-Mari Aro. Light has a specific role in modulating Arabidopsis gene expression at low temperature.
BMC plant biology.
2008 Jan; 8(?):13. doi:
10.1186/1471-2229-8-13. [PMID: 18230142] - Gen-ichiro Arimura, Stefan Garms, Massimo Maffei, Simone Bossi, Birgit Schulze, Margit Leitner, Axel Mithöfer, Wilhelm Boland. Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling.
Planta.
2008 Jan; 227(2):453-64. doi:
10.1007/s00425-007-0631-y. [PMID: 17924138] - Irene Lambrinoudaki, Sophia Vlachou, Fotini Galapi, Dimitra Papadimitriou, K Papadias. Once-yearly zoledronic acid in the prevention of osteoporotic bone fractures in postmenopausal women.
Clinical interventions in aging.
2008; 3(3):445-51. doi:
10.2147/cia.s2046. [PMID: 18982915] - Michael F Covington, Julin N Maloof, Marty Straume, Steve A Kay, Stacey L Harmer. Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development.
Genome biology.
2008; 9(8):R130. doi:
10.1186/gb-2008-9-8-r130. [PMID: 18710561] - Yoshiaki Sawada, Takumi Katsumata, Jun Kitamura, Hiroshi Kawaide, Masatoshi Nakajima, Tadao Asami, Kentaro Nakaminami, Toshihiro Kurahashi, Wataru Mitsuhashi, Yasunori Inoue, Tomonobu Toyomasu. Germination of photoblastic lettuce seeds is regulated via the control of endogenous physiologically active gibberellin content, rather than of gibberellin responsiveness.
Journal of experimental botany.
2008; 59(12):3383-93. doi:
10.1093/jxb/ern192. [PMID: 18653696] - Riccardo Velasco, Andrey Zharkikh, Michela Troggio, Dustin A Cartwright, Alessandro Cestaro, Dmitry Pruss, Massimo Pindo, Lisa M Fitzgerald, Silvia Vezzulli, Julia Reid, Giulia Malacarne, Diana Iliev, Giuseppina Coppola, Bryan Wardell, Diego Micheletti, Teresita Macalma, Marco Facci, Jeff T Mitchell, Michele Perazzolli, Glenn Eldredge, Pamela Gatto, Rozan Oyzerski, Marco Moretto, Natalia Gutin, Marco Stefanini, Yang Chen, Cinzia Segala, Christine Davenport, Lorenzo Demattè, Amy Mraz, Juri Battilana, Keith Stormo, Fabrizio Costa, Quanzhou Tao, Azeddine Si-Ammour, Tim Harkins, Angie Lackey, Clotilde Perbost, Bruce Taillon, Alessandra Stella, Victor Solovyev, Jeffrey A Fawcett, Lieven Sterck, Klaas Vandepoele, Stella M Grando, Stefano Toppo, Claudio Moser, Jerry Lanchbury, Robert Bogden, Mark Skolnick, Vittorio Sgaramella, Satish K Bhatnagar, Paolo Fontana, Alexander Gutin, Yves Van de Peer, Francesco Salamini, Roberto Viola. A high quality draft consensus sequence of the genome of a heterozygous grapevine variety.
PloS one.
2007 Dec; 2(12):e1326. doi:
10.1371/journal.pone.0001326. [PMID: 18094749] - Stefan A Rensing, Julia Ick, Jeffrey A Fawcett, Daniel Lang, Andreas Zimmer, Yves Van de Peer, Ralf Reski. An ancient genome duplication contributed to the abundance of metabolic genes in the moss Physcomitrella patens.
BMC evolutionary biology.
2007 Aug; 7(?):130. doi:
10.1186/1471-2148-7-130. [PMID: 17683536] - Yi Zhang, Zhongfu Ni, Yingyin Yao, Xiuling Nie, Qixin Sun. Gibberellins and heterosis of plant height in wheat (Triticum aestivum L.).
BMC genetics.
2007 Jun; 8(?):40. doi:
10.1186/1471-2156-8-40. [PMID: 17598921] - Jerome Grimplet, Laurent G Deluc, Richard L Tillett, Matthew D Wheatley, Karen A Schlauch, Grant R Cramer, John C Cushman. Tissue-specific mRNA expression profiling in grape berry tissues.
BMC genomics.
2007 Jun; 8(?):187. doi:
10.1186/1471-2164-8-187. [PMID: 17584945] - Nengguo Tao, Zhiyong Hu, Qin Liu, Juan Xu, Yunjiang Cheng, Linlin Guo, Wenwu Guo, Xiuxin Deng. Expression of phytoene synthase gene (Psy) is enhanced during fruit ripening of Cara Cara navel orange (Citrus sinensis Osbeck).
Plant cell reports.
2007 Jun; 26(6):837-43. doi:
10.1007/s00299-006-0289-0. [PMID: 17226057] - Francis X Cunningham, Elisabeth Gantt. A portfolio of plasmids for identification and analysis of carotenoid pathway enzymes: Adonis aestivalis as a case study.
Photosynthesis research.
2007 May; 92(2):245-59. doi:
10.1007/s11120-007-9210-0. [PMID: 17634749] - Gianfranco Diretto, Salim Al-Babili, Raffaela Tavazza, Velia Papacchioli, Peter Beyer, Giovanni Giuliano. Metabolic engineering of potato carotenoid content through tuber-specific overexpression of a bacterial mini-pathway.
PloS one.
2007 Apr; 2(4):e350. doi:
10.1371/journal.pone.0000350. [PMID: 17406674] - Sota Omoigui. The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.
Immunity & ageing : I & A.
2007 Mar; 4(?):1. doi:
10.1186/1742-4933-4-1. [PMID: 17374166] - Katalin Kovacs, Lina Zhang, Robert S T Linforth, Benjamin Whittaker, Christopher J Hayes, Rupert G Fray. Redirection of carotenoid metabolism for the efficient production of taxadiene [taxa-4(5),11(12)-diene] in transgenic tomato fruit.
Transgenic research.
2007 Feb; 16(1):121-6. doi:
10.1007/s11248-006-9039-x. [PMID: 17106766] - Motomichi Murakami, Kyohei Shibuya, Toru Nakayama, Tokuzo Nishino, Tohru Yoshimura, Hisashi Hemmi. Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus.
The FEBS journal.
2007 Feb; 274(3):805-14. doi:
10.1111/j.1742-4658.2006.05625.x. [PMID: 17288560] - E Ben-Tal Cohen, P J Hohensinner, C Kaun, G Maurer, K Huber, J Wojta. Statins decrease TNF-alpha-induced osteoprotegerin production by endothelial cells and smooth muscle cells in vitro.
Biochemical pharmacology.
2007 Jan; 73(1):77-83. doi:
10.1016/j.bcp.2006.09.007. [PMID: 17070781]