3,7,11,15-Tetramethylhexadeca-1,6,10,14-tetraene (BioDeep_00000185288)
human metabolite blood metabolite
代谢物信息卡片
3,7,11,15-Tetramethylhexadeca-1,6,10,14-tetraene
化学式: C20H34 (274.266)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CCC=C(C)CCC=C(C)CCC=C(C)C)C=C
InChI: InChI=1S/C20H34/c1-7-18(4)12-9-14-20(6)16-10-15-19(5)13-8-11-17(2)3/h7,11,14-15,18H,1,8-10,12-13,16H2,2-6H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Biochemistry.
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Journal of lipid research.
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Plant physiology.
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Biochemistry.
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Analytical biochemistry.
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British journal of cancer.
2008 Jun; 98(12):1951-8. doi:
10.1038/sj.bjc.6604402. [PMID: 18506143] - Magdalena Winiarska, Jacek Bil, Ewa Wilczek, Grzegorz M Wilczynski, Malgorzata Lekka, Patrick J Engelberts, Wendy J M Mackus, Elzbieta Gorska, Lukasz Bojarski, Tomasz Stoklosa, Dominika Nowis, Zuzanna Kurzaj, Marcin Makowski, Eliza Glodkowska, Tadeusz Issat, Piotr Mrowka, Witold Lasek, Anna Dabrowska-Iwanicka, Grzegorz W Basak, Maria Wasik, Krzysztof Warzocha, Maciej Sinski, Zbigniew Gaciong, Marek Jakobisiak, Paul W H I Parren, Jakub Golab. Statins impair antitumor effects of rituximab by inducing conformational changes of CD20.
PLoS medicine.
2008 Mar; 5(3):e64. doi:
10.1371/journal.pmed.0050064. [PMID: 18366248] - Amir Reza Jassbi, Klaus Gase, Christian Hettenhausen, Axel Schmidt, Ian T Baldwin. Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm.
Plant physiology.
2008 Mar; 146(3):974-86. doi:
10.1104/pp.107.108811. [PMID: 17965175] - Masahiro Ohsawa, Junpei Mutoh, Hiroaki Hisa. Mevalonate sensitizes the nociceptive transmission in the mouse spinal cord.
Pain.
2008 Feb; 134(3):285-292. doi:
10.1016/j.pain.2007.04.031. [PMID: 17764839] - Arto J Soitamo, Mirva Piippo, Yagut Allahverdiyeva, Natalia Battchikova, Eva-Mari Aro. Light has a specific role in modulating Arabidopsis gene expression at low temperature.
BMC plant biology.
2008 Jan; 8(?):13. doi:
10.1186/1471-2229-8-13. [PMID: 18230142] - Manuel Talon, Fred G Gmitter. Citrus genomics.
International journal of plant genomics.
2008; 2008(?):528361. doi:
10.1155/2008/528361. [PMID: 18509486] - André S T Irsigler, Maximiller D L Costa, Ping Zhang, Pedro A B Reis, Ralph E Dewey, Rebecca S Boston, Elizabeth P B Fontes. Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways.
BMC genomics.
2007 Nov; 8(?):431. doi:
10.1186/1471-2164-8-431. [PMID: 18036212] - Dominique Swennen, Jean-Marie Beckerich. Yarrowia lipolytica vesicle-mediated protein transport pathways.
BMC evolutionary biology.
2007 Nov; 7(?):219. doi:
10.1186/1471-2148-7-219. [PMID: 17997821] - Christopher M Carlin, Andrew J Peacock, David J Welsh. Fluvastatin inhibits hypoxic proliferation and p38 MAPK activity in pulmonary artery fibroblasts.
American journal of respiratory cell and molecular biology.
2007 Oct; 37(4):447-56. doi:
10.1165/rcmb.2007-0012oc. [PMID: 17556673] - Rita Rasteiro, Jose B Pereira-Leal. Multiple domain insertions and losses in the evolution of the Rab prenylation complex.
BMC evolutionary biology.
2007 Aug; 7(?):140. doi:
10.1186/1471-2148-7-140. [PMID: 17705859] - W Wei-Lynn Wong, James W Clendening, Anna Martirosyan, Paul C Boutros, Christina Bros, Fereshteh Khosravi, Igor Jurisica, A Keith Stewart, P Leif Bergsagel, Linda Z Penn. Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma.
Molecular cancer therapeutics.
2007 Jun; 6(6):1886-97. doi:
10.1158/1535-7163.mct-06-0745. [PMID: 17575117] - Francesco Epifano, Massimo Curini, Salvatore Genovese, Michelle Blaskovich, Andrew Hamilton, Said M Sebti. Prenyloxyphenylpropanoids as novel lead compounds for the selective inhibition of geranylgeranyl transferase I.
Bioorganic & medicinal chemistry letters.
2007 May; 17(9):2639-42. doi:
10.1016/j.bmcl.2007.01.097. [PMID: 17314046] - Sebastian Maurer-Stroh, Manfred Koranda, Wolfgang Benetka, Georg Schneider, Fernanda L Sirota, Frank Eisenhaber. Towards complete sets of farnesylated and geranylgeranylated proteins.
PLoS computational biology.
2007 Apr; 3(4):e66. doi:
10.1371/journal.pcbi.0030066. [PMID: 17411337] - Birgit Eisenhaber, Frank Eisenhaber. Posttranslational modifications and subcellular localization signals: indicators of sequence regions without inherent 3D structure?.
Current protein & peptide science.
2007 Apr; 8(2):197-203. doi:
10.2174/138920307780363424. [PMID: 17430201] - Sota Omoigui. The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.
Immunity & ageing : I & A.
2007 Mar; 4(?):1. doi:
10.1186/1742-4933-4-1. [PMID: 17374166] - M Wojtas, S Swiezewski, T J Sarnowski, D Plochocka, A Chelstowska, T Tolmachova, E Swiezewska. Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana.
Cell biology international.
2007 Mar; 31(3):246-51. doi:
10.1016/j.cellbi.2006.04.011. [PMID: 17140818] - J Igarashi, M Miyoshi, T Hashimoto, Y Kubota, H Kosaka. Statins induce S1P1 receptors and enhance endothelial nitric oxide production in response to high-density lipoproteins.
British journal of pharmacology.
2007 Feb; 150(4):470-9. doi:
10.1038/sj.bjp.0707114. [PMID: 17220911] - Motomichi Murakami, Kyohei Shibuya, Toru Nakayama, Tokuzo Nishino, Tohru Yoshimura, Hisashi Hemmi. Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus.
The FEBS journal.
2007 Feb; 274(3):805-14. doi:
10.1111/j.1742-4658.2006.05625.x. [PMID: 17288560] - Teresa A Garrett, Ziqiang Guan, Christian R H Raetz. Analysis of ubiquinones, dolichols, and dolichol diphosphate-oligosaccharides by liquid chromatography-electrospray ionization-mass spectrometry.
Methods in enzymology.
2007; 432(?):117-43. doi:
10.1016/s0076-6879(07)32005-3. [PMID: 17954215] - Ping L Zhang, Albert T Quiery, Thomas M Blasick, Robert E Brown. Morphoproteomic expression of H-ras (p21ras) correlates with serum monoclonal immunoglobulin reduction in multiple myeloma patients following pamidronate treatment.
Annals of clinical and laboratory science.
2007; 37(1):34-8. doi:
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Nature chemical biology.
2006 Nov; 2(11):584-90. doi:
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Kidney international.
2006 Oct; 70(7):1296-304. doi:
10.1038/sj.ki.5001713. [PMID: 16929252] - Niels R Veillard, Vincent Braunersreuther, Claire Arnaud, Fabienne Burger, Graziano Pelli, Sabine Steffens, François Mach. Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages.
Atherosclerosis.
2006 Sep; 188(1):51-8. doi:
10.1016/j.atherosclerosis.2005.10.015. [PMID: 16321392] - Sasmita Mohanty, Bernhard Grimm, Baishnab C Tripathy. Light and dark modulation of chlorophyll biosynthetic genes in response to temperature.
Planta.
2006 Aug; 224(3):692-9. doi:
10.1007/s00425-006-0248-6. [PMID: 16523349] - Enriqueta Alós, Manuel Cercós, María-Jesús Rodrigo, Lorenzo Zacarías, Manuel Talón. Regulation of color break in citrus fruits. Changes in pigment profiling and gene expression induced by gibberellins and nitrate, two ripening retardants.
Journal of agricultural and food chemistry.
2006 Jun; 54(13):4888-95. doi:
10.1021/jf0606712. [PMID: 16787044] - Bettina Couderc, Marie Penary, Mustapha Tohfe, Anne Pradines, Antoine Casteignau, Danièle Berg, Gilles Favre. Reversible inactivation of the transcriptional function of P53 protein by farnesylation.
BMC biotechnology.
2006 May; 6(?):26. doi:
10.1186/1472-6750-6-26. [PMID: 16732889] - Beatrice Dursina, Reinhard Reents, Christine Delon, Yaowen Wu, Mahesh Kulharia, Michael Thutewohl, Alexei Veligodsky, Alexandr Kalinin, Vladimir Evstifeev, Doina Ciobanu, Stefan E Szedlacsek, Herbert Waldmann, Roger S Goody, Kirill Alexandrov. Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids.
Journal of the American Chemical Society.
2006 Mar; 128(9):2822-35. doi:
10.1021/ja052196e. [PMID: 16506760] - Ka Fai Leung, Rudi Baron, Miguel C Seabra. Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.
Journal of lipid research.
2006 Mar; 47(3):467-75. doi:
10.1194/jlr.r500017-jlr200. [PMID: 16401880] - Chang-Seon Myung, William K Lim, Joseph M DeFilippo, Hiroshi Yasuda, Richard R Neubig, James C Garrison. Regions in the G protein gamma subunit important for interaction with receptors and effectors.
Molecular pharmacology.
2006 Mar; 69(3):877-87. doi:
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BMC biochemistry.
2006 Feb; 7(?):6. doi:
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