3,5,5-Trimethyl-4-[3,7,12,16-tetramethyl-18-(2,2,6-trimethyl-4,5-dioxocyclohexyl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexane-1,2-dione (BioDeep_00000185283)

   

human metabolite blood metabolite


代谢物信息卡片


3,5,5-trimethyl-4-[3,7,12,16-tetramethyl-18-(2,2,6-trimethyl-4,5-dioxocyclohexyl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohexane-1,2-dione

化学式: C40H52O4 (596.3865392)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1C(C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC2C(C)C(=O)C(=O)CC2(C)C)C(C)(C)CC(=O)C1=O
InChI: InChI=1S/C40H52O4/c1-27(17-13-19-29(3)21-23-33-31(5)37(43)35(41)25-39(33,7)8)15-11-12-16-28(2)18-14-20-30(4)22-24-34-32(6)38(44)36(42)26-40(34,9)10/h11-24,31-34H,25-26H2,1-10H3



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Assaad Sila, Moncef Nasri, Ali Bougatef. Isolation and characterisation of carotenoproteins from deep-water pink shrimp processing waste. International journal of biological macromolecules. 2012 Dec; 51(5):953-9. doi: 10.1016/j.ijbiomac.2012.07.011. [PMID: 22813933]
  • Baldo F Cordero, Inmaculada Couso, Rosa Leon, Herminia Rodriguez, Maria Angeles Vargas. Isolation and characterization of a lycopene ε-cyclase gene of Chlorella (Chromochloris) zofingiensis. Regulation of the carotenogenic pathway by nitrogen and light. Marine drugs. 2012 Sep; 10(9):2069-2088. doi: 10.3390/md10092069. [PMID: 23118722]
  • Makoto Inoue, Hiroki Tanabe, Akira Matsumoto, Michiyo Takagi, Keizo Umegaki, Sakae Amagaya, Jiro Takahashi. Astaxanthin functions differently as a selective peroxisome proliferator-activated receptor γ modulator in adipocytes and macrophages. Biochemical pharmacology. 2012 Sep; 84(5):692-700. doi: 10.1016/j.bcp.2012.05.021. [PMID: 22732454]
  • Charlotte Sy, Beatrice Gleize, Olivier Dangles, Jean-François Landrier, Catherine Caris Veyrat, Patrick Borel. Effects of physicochemical properties of carotenoids on their bioaccessibility, intestinal cell uptake, and blood and tissue concentrations. Molecular nutrition & food research. 2012 Sep; 56(9):1385-97. doi: 10.1002/mnfr.201200041. [PMID: 22815251]
  • Rosemari Otton, Douglas Popp Marin, Anaysa Paola Bolin, Rita de Cássia Santos Macedo, Thais Regina Campoio, Claudio Fineto, Beatriz Alves Guerra, José Roberto Leite, Marcelo Paes Barros, Rita Mattei. Combined fish oil and astaxanthin supplementation modulates rat lymphocyte function. European journal of nutrition. 2012 Sep; 51(6):707-18. doi: 10.1007/s00394-011-0250-z. [PMID: 21972007]
  • Kenta Murata, Atsushi Oyagi, Dai Takahira, Kazuhiro Tsuruma, Masamitsu Shimazawa, Takashi Ishibashi, Hideaki Hara. Protective effects of astaxanthin from Paracoccus carotinifaciens on murine gastric ulcer models. Phytotherapy research : PTR. 2012 Aug; 26(8):1126-32. doi: 10.1002/ptr.3681. [PMID: 22170791]
  • B Djordjevic, I Baralic, J Kotur-Stevuljevic, A Stefanovic, J Ivanisevic, N Radivojevic, M Andjelkovic, N Dikic. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. The Journal of sports medicine and physical fitness. 2012 Aug; 52(4):382-92. doi: NULL. [PMID: 22828460]
  • Susumu Hama, Kanako Takahashi, Yuko Inai, Kanako Shiota, Ryota Sakamoto, Asako Yamada, Hiroyuki Tsuchiya, Kiyoshi Kanamura, Eiji Yamashita, Kentaro Kogure. Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation on ultraviolet-induced skin damage. Journal of pharmaceutical sciences. 2012 Aug; 101(8):2909-16. doi: 10.1002/jps.23216. [PMID: 22628205]
  • Junchao Huang, Yujuan Zhong, Gerhard Sandmann, Jin Liu, Feng Chen. Cloning and selection of carotenoid ketolase genes for the engineering of high-yield astaxanthin in plants. Planta. 2012 Aug; 236(2):691-9. doi: 10.1007/s00425-012-1654-6. [PMID: 22526507]
  • Eliseu Rodrigues, Lilian R B Mariutti, Adriana Z Mercadante. Scavenging capacity of marine carotenoids against reactive oxygen and nitrogen species in a membrane-mimicking system. Marine drugs. 2012 Aug; 10(8):1784-1798. doi: 10.3390/md10081784. [PMID: 23015774]
  • Jin Niu, Chun-Hou Li, Yong-Jian Liu, Li-Xia Tian, Xu Chen, Zhong Huang, Hei-Zhao Lin. Dietary values of astaxanthin and canthaxanthin in Penaeus monodon in the presence and absence of cholesterol supplementation: effect on growth, nutrient digestibility and tissue carotenoid composition. The British journal of nutrition. 2012 Jul; 108(1):80-91. doi: 10.1017/s0007114511005423. [PMID: 22142867]
  • Paula R Augusti, Andréia Quatrin, Sabrina Somacal, Greicy Mm Conterato, Rocheli Sobieski, Amanda R Ruviaro, Luana H Maurer, Marta Mf Duarte, Miguel Roehrs, Tatiana Emanuelli. Astaxanthin prevents changes in the activities of thioredoxin reductase and paraoxonase in hypercholesterolemic rabbits. Journal of clinical biochemistry and nutrition. 2012 Jul; 51(1):42-9. doi: 10.3164/jcbn.11-74. [PMID: 22798712]
  • Fareha Bano, Sunaina Zutshi, Tasneem Fatma. Chromium (VI) induced oxidative stress in Hapalosiphon fontinalis. World journal of microbiology & biotechnology. 2012 Jul; 28(7):2505-11. doi: 10.1007/s11274-012-1058-6. [PMID: 22806156]
  • Noriko Kashima, Yukiko Fujikura, Tomomi Komura, Shogo Fujiwara, Miyuki Sakamoto, Keiji Terao, Yoshikazu Nishikawa. Development of a method for oral administration of hydrophobic substances to Caenorhabditis elegans: pro-longevity effects of oral supplementation with lipid-soluble antioxidants. Biogerontology. 2012 Jun; 13(3):337-44. doi: 10.1007/s10522-012-9378-3. [PMID: 22484623]
  • Yaoyao Jia, Jin-Young Kim, Hee-Jin Jun, Sun-Joong Kim, Ji-Hae Lee, Minh Hien Hoang, Kwang-Yeon Hwang, Soo-Jong Um, Hyo Ihl Chang, Sung-Joon Lee. The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes. Molecular nutrition & food research. 2012 Jun; 56(6):878-88. doi: 10.1002/mnfr.201100798. [PMID: 22707263]
  • Graziano Riccioni, Lorenza Speranza, Mirko Pesce, Salvatore Cusenza, Nicolantonio D'Orazio, Michael J Glade. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. Nutrition (Burbank, Los Angeles County, Calif.). 2012 Jun; 28(6):605-10. doi: 10.1016/j.nut.2011.11.028. [PMID: 22480801]
  • Sung Kee Ryu, Timothy J King, Kazutoshi Fujioka, Jennifer Pattison, Fredrick J Pashkow, Sotirios Tsimikas. Effect of an oral astaxanthin prodrug (CDX-085) on lipoprotein levels and progression of atherosclerosis in LDLR(-/-) and ApoE(-/-) mice. Atherosclerosis. 2012 May; 222(1):99-105. doi: 10.1016/j.atherosclerosis.2012.02.002. [PMID: 22406426]
  • Marcelo Paes Barros, Douglas Popp Marin, Anaysa Paola Bolin, Rita de Cássia Santos Macedo, Thais Regina Campoio, Claudio Fineto, Beatriz Alves Guerra, Tatiana Geraldo Polotow, Cristina Vardaris, Rita Mattei, Rosemari Otton. Combined astaxanthin and fish oil supplementation improves glutathione-based redox balance in rat plasma and neutrophils. Chemico-biological interactions. 2012 Apr; 197(1):58-67. doi: 10.1016/j.cbi.2012.03.005. [PMID: 22465178]
  • Jin Liu, Junchao Huang, Yue Jiang, Feng Chen. Molasses-based growth and production of oil and astaxanthin by Chlorella zofingiensis. Bioresource technology. 2012 Mar; 107(?):393-8. doi: 10.1016/j.biortech.2011.12.047. [PMID: 22221991]
  • Laurie A Walker, Tong Wang, Hongwei Xin, David Dolde. Supplementation of laying-hen feed with palm tocos and algae astaxanthin for egg yolk nutrient enrichment. Journal of agricultural and food chemistry. 2012 Feb; 60(8):1989-99. doi: 10.1021/jf204763f. [PMID: 22276647]
  • Elumalai Arunkumar, Saravanan Bhuvaneswari, Carani Venkatraman Anuradha. An intervention study in obese mice with astaxanthin, a marine carotenoid--effects on insulin signaling and pro-inflammatory cytokines. Food & function. 2012 Feb; 3(2):120-6. doi: 10.1039/c1fo10161g. [PMID: 22089895]
  • Kung-Chi Chan, Pei-Jain Pen, Mei-Chin Yin. Anticoagulatory and antiinflammatory effects of astaxanthin in diabetic rats. Journal of food science. 2012 Feb; 77(2):H76-80. doi: 10.1111/j.1750-3841.2011.02558.x. [PMID: 22309505]
  • Matthew B Toomey, Kevin J McGraw. Mate choice for a male carotenoid-based ornament is linked to female dietary carotenoid intake and accumulation. BMC evolutionary biology. 2012 Jan; 12(?):3. doi: 10.1186/1471-2148-12-3. [PMID: 22233462]
  • Zhengquan Gao, Chunxiao Meng, Xiaowen Zhang, Dong Xu, Yuefeng Zhao, Yitao Wang, Hongxin Lv, Liming Yang, Lingling Chen, Naihao Ye. Differential expression of carotenogenic genes, associated changes on astaxanthin production and photosynthesis features induced by JA in H. pluvialis. PloS one. 2012; 7(8):e42243. doi: 10.1371/journal.pone.0042243. [PMID: 22870309]
  • Piyachat Chansela, Naoko Goto-Inoue, Nobuhiro Zaima, Takahiro Hayasaka, Morakot Sroyraya, Napamanee Kornthong, Attakorn Engsusophon, Montakan Tamtin, Chatchawalee Chaisri, Prasert Sobhon, Mitsutoshi Setou. Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. PloS one. 2012; 7(3):e33154. doi: 10.1371/journal.pone.0033154. [PMID: 22432001]
  • Daniel Garama, Phil Bremer, Alan Carne. Extraction and analysis of carotenoids from the New Zealand sea urchin Evechinus chloroticus gonads. Acta biochimica Polonica. 2012; 59(1):83-5. doi: . [PMID: 22428140]
  • Hitomi Okada, Yuji Naito, Tomohisa Takagi, Megumi Takaoka, Tomoko Oya-Ito, Kohei Fukumoto, Kazuhiko Uchiyama, Osamu Handa, Satoshi Kokura, Yumiko Nagano, Hirofumi Matsui, Yoji Kato, Toshihiko Osawa, Toshikazu Yoshikawa. Detection of N-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells. Journal of clinical biochemistry and nutrition. 2012 Jan; 50(1):47-52. doi: 10.3164/jcbn.11-39. [PMID: 22247600]
  • Alessandra Ferramosca, Annalea Conte, Lena Burri, Kjetil Berge, Francesco De Nuccio, Anna Maria Giudetti, Vincenzo Zara. A krill oil supplemented diet suppresses hepatic steatosis in high-fat fed rats. PloS one. 2012; 7(6):e38797. doi: 10.1371/journal.pone.0038797. [PMID: 22685607]
  • Yi-Fang Li, Rong-Rong He, Bun Tsoi, Xiao-Di Li, Wei-Xi Li, Keiichi Abe, Hiroshi Kurihara. Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance. PloS one. 2012; 7(4):e33190. doi: 10.1371/journal.pone.0033190. [PMID: 22511917]
  • Kang-Hao He, Xiao-Li Zou, Xiang Liu, Hong-Yan Zeng. [Determination of canthaxanthin and astaxanthin in egg yolks by reversed phase high performance liquid chromatography with diode array detection]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2012 Jan; 43(1):113-7. doi: ". [PMID: 22455145]
  • Diego Libkind, Martín Moliné, Celia Tognetti. Isolation and selection of new astaxanthin producing strains of Xanthophyllomyces dendrorhous. Methods in molecular biology (Clifton, N.J.). 2012; 898(?):183-94. doi: 10.1007/978-1-61779-918-1_12. [PMID: 22711126]
  • Mauro Cellini, Roberto Gattegna, Pier Giorgio Toschi, Ernesto Strobbe, Emilio C Campos. Multifocal electroretinogram and Optical Coherence tomography spectral-domain in arc welding macular injury: a case report. BMC ophthalmology. 2011 Dec; 11(?):40. doi: 10.1186/1471-2415-11-40. [PMID: 22208163]
  • Jean Soon Park, Bridget D Mathison, Michael G Hayek, Stefan Massimino, Gregory A Reinhart, Boon P Chew. Astaxanthin stimulates cell-mediated and humoral immune responses in cats. Veterinary immunology and immunopathology. 2011 Dec; 144(3-4):455-61. doi: 10.1016/j.vetimm.2011.08.019. [PMID: 21930306]
  • Hye Duck Choi, Ji Hae Kim, Min Jung Chang, Yeo Kyu-Youn, Wan Gyoon Shin. Effects of astaxanthin on oxidative stress in overweight and obese adults. Phytotherapy research : PTR. 2011 Dec; 25(12):1813-8. doi: 10.1002/ptr.3494. [PMID: 21480416]
  • Kazuaki Takahashi, Tetsuya Takimoto, Kan Sato, Yukio Akiba. Effect of dietary supplementation of astaxanthin from Phaffia rhodozyma on lipopolysaccharide-induced early inflammatory responses in male broiler chickens (Gallus gallus) fed a corn-enriched diet. Animal science journal = Nihon chikusan Gakkaiho. 2011 Dec; 82(6):753-8. doi: 10.1111/j.1740-0929.2011.00898.x. [PMID: 22111631]
  • Michael S Donaldson. A carotenoid health index based on plasma carotenoids and health outcomes. Nutrients. 2011 12; 3(12):1003-22. doi: 10.3390/nu3121003. [PMID: 22292108]
  • Giuseppe Marazzi, Luca Cacciotti, Francesco Pelliccia, Luigi Iaia, Maurizio Volterrani, Giuseppe Caminiti, Barbara Sposato, Rosalba Massaro, Fabrizia Grieco, Giuseppe Rosano. Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. Advances in therapy. 2011 Dec; 28(12):1105-13. doi: 10.1007/s12325-011-0082-5. [PMID: 22113535]
  • José Miguel Araya-Garay, Lucía Feijoo-Siota, Patricia Veiga-Crespo, Tomás González Villa. cDNA cloning of a novel gene codifying for the enzyme lycopene β-cyclase from Ficus carica and its expression in Escherichia coli. Applied microbiology and biotechnology. 2011 Nov; 92(4):769-77. doi: 10.1007/s00253-011-3488-8. [PMID: 21792589]
  • Hye Duck Choi, Yeo Kyu Youn, Wan Gyoon Shin. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant foods for human nutrition (Dordrecht, Netherlands). 2011 Nov; 66(4):363-9. doi: 10.1007/s11130-011-0258-9. [PMID: 21964877]
  • Fan Yang, Mo-Ran Wang, Yu-Guang Ma, Wen-Ming Ma, Wei-Jun Yang. Prawn lipocalin: characterization of a color shift induced by gene knockdown and ligand binding assay. Journal of experimental zoology. Part A, Ecological genetics and physiology. 2011 Nov; 315(9):562-71. doi: 10.1002/jez.706. [PMID: 21905240]
  • C P Earnest, M Lupo, K M White, T S Church. Effect of astaxanthin on cycling time trial performance. International journal of sports medicine. 2011 Nov; 32(11):882-8. doi: 10.1055/s-0031-1280779. [PMID: 21984399]
  • Jian Li, Daling Zhu, Jianfeng Niu, Songdong Shen, Guangce Wang. An economic assessment of astaxanthin production by large scale cultivation of Haematococcus pluvialis. Biotechnology advances. 2011 Nov; 29(6):568-74. doi: 10.1016/j.biotechadv.2011.04.001. [PMID: 21497650]
  • Chun-chao Han, Hong Wei, Jianyou Guo. Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study. BMC complementary and alternative medicine. 2011 Oct; 11(?):100. doi: 10.1186/1472-6882-11-100. [PMID: 22026927]
  • Janet C Tou, Stephanie N Altman, Joseph C Gigliotti, Vagner A Benedito, Elizabeth L Cordonier. Different sources of omega-3 polyunsaturated fatty acids affects apparent digestibility, tissue deposition, and tissue oxidative stability in growing female rats. Lipids in health and disease. 2011 Oct; 10(?):179. doi: 10.1186/1476-511x-10-179. [PMID: 21999902]
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  • Yasuto Sasaki, Nozomi Kobara, Saori Higashino, John C Giddings, Junichiro Yamamoto. Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats. Nutrition research (New York, N.Y.). 2011 Oct; 31(10):784-9. doi: 10.1016/j.nutres.2011.09.010. [PMID: 22074803]
  • Natália Mezzomo, Bianca Maestri, Renata Lazzaris dos Santos, Marcelo Maraschin, Sandra R S Ferreira. Pink shrimp (P. brasiliensis and P. paulensis) residue: influence of extraction method on carotenoid concentration. Talanta. 2011 Sep; 85(3):1383-91. doi: 10.1016/j.talanta.2011.06.018. [PMID: 21807199]
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  • Rita Mattei, Tatiana G Polotow, Cristina V Vardaris, Beatriz A Guerra, José Roberto Leite, Rosemari Otton, Marcelo P Barros. Astaxanthin limits fish oil-related oxidative insult in the anterior forebrain of Wistar rats: putative anxiolytic effects?. Pharmacology, biochemistry, and behavior. 2011 Sep; 99(3):349-55. doi: 10.1016/j.pbb.2011.05.009. [PMID: 21619892]
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  • Pilar Martinez-Moya, Steven Alexander Watt, Karsten Niehaus, Jennifer Alcaíno, Marcelo Baeza, Víctor Cifuentes. Proteomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous. BMC microbiology. 2011 Jun; 11(?):131. doi: 10.1186/1471-2180-11-131. [PMID: 21669001]
  • Yu-Juan Zhong, Jun-Chao Huang, Jin Liu, Yin Li, Yue Jiang, Zeng-Fu Xu, Gerhard Sandmann, Feng Chen. Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis. Journal of experimental botany. 2011 Jun; 62(10):3659-69. doi: 10.1093/jxb/err070. [PMID: 21398427]
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  • Yingying Zhao, Feifei Guan, Guili Wang, Lili Miao, Jing Ding, Guohua Guan, Ying Li, Bodi Hui. Astaxanthin preparation by lipase-catalyzed hydrolysis of its esters from Haematococcus pluvialis algal extracts. Journal of food science. 2011 May; 76(4):C643-50. doi: 10.1111/j.1750-3841.2011.02119.x. [PMID: 22417348]
  • Jian Ma, Hai-min Chen, Xiao-jun Yan, Feng Wang, Wei-feng Xu. [Astaxanthin inhibits sodium azide-induced cytotoxicity in hepatocyte L-02 cells probably by H+ transferring function]. Yao xue xue bao = Acta pharmaceutica Sinica. 2011 May; 46(5):521-6. doi: ". [PMID: 21800538]
  • Boon P Chew, Bridget D Mathison, Michael G Hayek, Stefan Massimino, Gregory A Reinhart, Jean Soon Park. Dietary astaxanthin enhances immune response in dogs. Veterinary immunology and immunopathology. 2011 Apr; 140(3-4):199-206. doi: 10.1016/j.vetimm.2010.12.004. [PMID: 21208664]
  • Ernst Weber, Carola Engler, Ramona Gruetzner, Stefan Werner, Sylvestre Marillonnet. A modular cloning system for standardized assembly of multigene constructs. PloS one. 2011 Feb; 6(2):e16765. doi: 10.1371/journal.pone.0016765. [PMID: 21364738]
  • Codruta Ignea, Ivana Cvetkovic, Sofia Loupassaki, Panagiotis Kefalas, Christopher B Johnson, Sotirios C Kampranis, Antonios M Makris. Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. Microbial cell factories. 2011 Jan; 10(?):4. doi: 10.1186/1475-2859-10-4. [PMID: 21276210]
  • Qiuling He, Ye Shen, Mingxiu Wang, Minren Huang, Ruizhen Yang, Shuijin Zhu, Liangsheng Wang, Yanjun Xu, Rongling Wu. Natural variation in petal color in Lycoris longituba revealed by anthocyanin components. PloS one. 2011; 6(8):e22098. doi: 10.1371/journal.pone.0022098. [PMID: 21829604]
  • Christine Boesch-Saadatmandi, Gerald Rimbach, Alexander Jungblut, Jan Frank. Comparison of tetrahydrofuran, fetal calf serum, and Tween 40 for the delivery of astaxanthin and canthaxanthin to HepG2 cells. Cytotechnology. 2011 Jan; 63(1):89-97. doi: 10.1007/s10616-010-9324-7. [PMID: 21153438]
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