tetranor-PGFM (BioDeep_00000184298)

   

human metabolite blood metabolite


代谢物信息卡片


9 alpha,11 alpha-Dihydroxy-15-oxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid

化学式: C16H26O7 (330.16784459999997)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CCC(=O)O)CC(=O)CC[C@@H]1[C@@H](CCC(=O)O)[C@H](C[C@H]1O)O
InChI: InChI=1S/C16H26O7/c17-10(3-1-2-4-15(20)21)5-6-11-12(7-8-16(22)23)14(19)9-13(11)18/h11-14,18-19H,1-9H2,(H,20,21)(H,22,23)

描述信息

同义名列表

18 个代谢物同义名

9 alpha,11 alpha-Dihydroxy-15-oxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid; 9alpha, 11alpha-Dihydroxy-15-oxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid; 9,11-Dihydroxy-15-oxo-2,3,4,5,20-pentanor-19-carboxyprostanoic acid; 8-[2-(2-carboxyethyl)-3,5-dihydroxycyclopentyl]-6-oxooctanoic acid; 5 alpha,7 alpha-Dihydroxy-11-ketotetranorprostane-1,16-dioic acid; 5 alpha,7 alpha-Dihydroxy-11-ketotetranorprostane 1,16-dioic acid; 8-[2-(2-Carboxyethyl)-3,5-dihydroxycyclopentyl]-6-oxooctanoate; 5,7-Dihydroxy-11-keto-tetranorprosta-1,16-dioic acid; Prostaglandin F2alpha urinary metabolite; Prostaglandin F-main urinary metabolite; PGF-Main urinary metabolite; Prostaglandin F-m; tetranor-PGFM; PGF2alpha UM; 9,11-DPPCPA; 5,7-DKPDA; PGF-MUM; PGF-m



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Duo Wei, Wan-Yuan He, Qian-Zhou Lv. Effect of nisoldipine and olmesartan on endothelium-dependent vasodilation in essential hypertensive patients. CNS neuroscience & therapeutics. 2012 May; 18(5):400-5. doi: 10.1111/j.1755-5949.2012.00304.x. [PMID: 22533725]
  • H Schweer, C O Meese, H W Seyberth. Determination of 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostan oic acid and 9 alpha,11 alpha-dihydroxy-15-oxo-2,3,4,5,20-pentanor-19-carboxyprostanoi c acid by gas chromatography/negative ion chemical ionization triple-stage quadrupole mass spectrometry. Analytical biochemistry. 1990 Aug; 189(1):54-8. doi: 10.1016/0003-2697(90)90043-9. [PMID: 2278391]
  • M Uchiyama, K Sakai. Increased main urinary metabolite of prostaglandin F2 alpha excretion in childhood migraine. Archives of disease in childhood. 1988 Mar; 63(3):342. doi: 10.1136/adc.63.3.342-a. [PMID: 3162670]
  • A Ferretti, V P Flanagan, J M Roman. Use of a homologous internal standard for the quantification of the major metabolite of prostaglandin F2 alpha in human urine by multiple ion analysis. Analytical biochemistry. 1984 Jan; 136(1):217-22. doi: 10.1016/0003-2697(84)90328-2. [PMID: 6711810]
  • H Katayama, H Hori. The influence of ultraviolet B irradiation on the excretion of the main urinary metabolite of prostaglandin F1 alpha and F2 alpha in psoriatic and normal subjects. Acta dermato-venereologica. 1984; 64(1):1-4. doi: NULL. [PMID: 6203274]
  • P Strömberg, M Akerlund, M L Forsling, H Kindahl. Involvement of prostaglandins in vasopressin stimulation of the human uterus. British journal of obstetrics and gynaecology. 1983 Apr; 90(4):332-7. doi: 10.1111/j.1471-0528.1983.tb08919.x. [PMID: 6573182]
  • H Katayama, A Kawada, C Endoh, H Hori, K Yoshikawa. Reduced excretion of the main urinary metabolite of prostaglandin F1 alpha and F2 alpha in psoriatic patients. Acta dermato-venereologica. 1983; 63(3):233-5. doi: NULL. [PMID: 6192638]
  • E Granström, H Kindahl, M L Swahn. Profiles of prostaglandin metabolites in the human circulation. Identification of late-appearing, long-lived products. Biochimica et biophysica acta. 1982 Oct; 713(1):46-60. doi: 10.1016/0005-2760(82)90165-5. [PMID: 6958332]
  • Y Kawai. [Luteolysis in the pseudopregnant rabbit and endogenous prostaglandin (PG) F2 alpha (author's transl)]. Nihon Sanka Fujinka Gakkai zasshi. 1982 May; 34(5):609-17. doi: NULL. [PMID: 6953157]
  • M Silver, A L Fowden. Uterine prostaglandin F metabolite production in relation to glucose availability in late pregnancy and a possible influence of diet on time of delivery in the mare. Journal of reproduction and fertility. Supplement. 1982; 32(?):511-9. doi: NULL. [PMID: 6962892]
  • D P Leadon, P D Rossdale, L B Jeffcott, W R Allen. A comparison of agents for inducing parturition in mares in the pre-viable and premature periods of gestation. Journal of reproduction and fertility. Supplement. 1982; 32(?):597-602. doi: NULL. [PMID: 6962901]
  • A R Brash. Quantitation of the major urinary metabolite of PGF2 alpha in the human by GC-MS. Methods in enzymology. 1982; 86(?):579-85. doi: 10.1016/0076-6879(82)86228-9. [PMID: 6957704]
  • E Granström, H Kindahl. Radioimmunoassay of 5 alpha, 7 alpha-dihydroxy-11-ketotetranorprostane-1,16-dioic acid, a major prostaglandin F metabolite in blood and urine. Methods in enzymology. 1982; 86(?):339-53. doi: 10.1016/0076-6879(82)86205-8. [PMID: 7132762]
  • D V Briffa, M W Greaves, C N Hensby. The influence of 8-methoxypsoralen plus UV-A (PUVA) on the excretion of the main urinary metabolite of prostaglandins F 1 alpha and F 2 alpha in patients with psoriasis. Clinical and experimental dermatology. 1981 Sep; 6(5):471-6. doi: 10.1111/j.1365-2230.1981.tb02337.x. [PMID: 7318237]
  • K Satoh, Y Kawai, N Mitsuhashi, K Kinoshita, S Sakamoto. Prostaglandin F2 alpha metabolites in plasma and urine during pseudopregnancy in the rabbit. American journal of obstetrics and gynecology. 1980 Dec; 138(7 Pt 1):748-54. doi: 10.1016/s0002-9378(16)32730-2. [PMID: 7446606]
  • I B Davies, R Bannister, C Hensby, P S Sever. The pressor actions of noradrenaline and angiotension II in chronic autonomic failure treated with indomethacin. British journal of clinical pharmacology. 1980 Sep; 10(3):223-9. doi: 10.1111/j.1365-2125.1980.tb01748.x. [PMID: 7437238]
  • M Murao, K Uchiyama, W Takahashi, F Hirata, T Inagawa. Clinical evaluation of main urinary metabolite of PGFs in chronic lung diseases. Advances in prostaglandin and thromboxane research. 1980; 7(?):965-8. doi: NULL. [PMID: 7369061]