(6S)-2-Amino-6-[(1S,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one (BioDeep_00000183524)

Main id: BioDeep_00000001257

 

human metabolite PANOMIX_OTCML-2023 blood metabolite Volatile Flavor Compounds


代谢物信息卡片


2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone

化学式: C9H15N5O3 (241.11748400000002)
中文名称: 四氢生物喋呤
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
InChI: InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)

描述信息

Tetrahydrobiopterin or BH4 is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase. A defect in BH4 production and/or a defect in the enzyme dihydropteridine reductase (DHPR) causes phenylketonuria type IV, as well as dopa-responsive dystonias. -- Wikipedia. [HMDB]
Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

同义名列表

34 个代谢物同义名

2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone; (6S)-2-Amino-6-[(1S,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-3H-pteridin-4-one; L-erythro-2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinon; (1R,2S)-(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-Pteridinyl)-1,2-propandiol; 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone; 5,6,7,8-tetrahydro-2-amino-6-(1,2-Dihydroxypropyl)-4(1H)-pteridinone; 2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone; 2-amino-6-(1,2-dihydroxypropyl)-1,4,5,6,7,8-hexahydropteridin-4-one; 5,6,7,8-Tetrahydrobiopterin, (S-(r*,s*))-isomer; 6R-L-erythro-5,6,7,8-Tetrahydrobiopterin; 1-Butanone, 1-(2,4,5-trihydroxyphenyl); 5,6,7,8-tetrahydro-L-Erythrobiopterin; 5,6,7,8-erythro-Tetrahydrobiopterin; Phenylalanine hydroxylase cofactor; 5,6,7,8-Tetrahydrodictyopterin; 2,4,5-Trihydroxybutyrophenone; 2,4,5-trihydroxybutyrophenone; 5,6,7,8-Tetrahydrobiopterin; Sapropterin dihydrochloride; D-threo-Tetrahydrobiopterin; 5,6,7,8-Tetra-H-biopterin; Trihydroxybutyrophenone; tetrahydro-6-Biopterin; Tetra-hydro-biopterin; tetrahydrobiopterin; Tetra-H-biopterin; Sapropterin; 6R-BH4; Kuvan; THBP; BPH4; BH4; (Rac)-Sapropterin; Tetrahydrobiopterin



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代谢反应

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1 个相关的物种来源信息

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  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
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