3-[4-(2-Methylpropyl)phenyl]-2-oxobutane-1-sulfonamide (BioDeep_00000183305)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H21NO3S (283.12420760000003)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 12.5%
分子结构信息
SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)CS(=O)(=O)N
InChI: InChI=1S/C14H21NO3S/c1-10(2)8-12-4-6-13(7-5-12)11(3)14(16)9-19(15,17)18/h4-7,10-11H,8-9H2,1-3H3,(H2,15,17,18)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hye Young Kim, Jin Hee Choi, Young Jin Kang, So Young Park, Hyoung Chul Choi, Hee Sun Kim. Reparixin, an inhibitor of CXCR1 and CXCR2 receptor activation, attenuates blood pressure and hypertension-related mediators expression in spontaneously hypertensive rats.
Biological & pharmaceutical bulletin.
2011; 34(1):120-7. doi:
10.1248/bpb.34.120. [PMID: 21212529] - S M Vieira, H P Lemos, R Grespan, M H Napimoga, D Dal-Secco, A Freitas, T M Cunha, W A Verri, D A Souza-Junior, M C Jamur, K S Fernandes, C Oliver, J S Silva, M M Teixeira, F Q Cunha. A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5.
British journal of pharmacology.
2009 Oct; 158(3):779-89. doi:
10.1111/j.1476-5381.2009.00367.x. [PMID: 19702783] - Roberto Anacardio, Frank G P Mullins, Sally Hannam, Muhammed S Sheikh, Karen O'Shea, Andrea Aramini, Gaetano D'Anniballe, Loredana D'Anteo, Mauro P Ferrari, Marcello Allegretti. Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Jul; 877(22):2087-92. doi:
10.1016/j.jchromb.2009.05.051. [PMID: 19539545] - I Midgley, K Fitzpatrick, S J Wright, B A John, A J Peard, R M Major, J D Holding, A McBurney, R Anacardio, R Novellini, M P Ferrari. Species differences in the pharmacokinetics and metabolism of reparixin in rat and dog.
Xenobiotica; the fate of foreign compounds in biological systems.
2006 May; 36(5):419-40. doi:
10.1080/00498250600646517. [PMID: 16854780] - Daniela Cugini, Nadia Azzollini, Elena Gagliardini, Paola Cassis, Riccardo Bertini, Francesco Colotta, Marina Noris, Giuseppe Remuzzi, Ariela Benigni. Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion.
Kidney international.
2005 May; 67(5):1753-61. doi:
10.1111/j.1523-1755.2005.00272.x. [PMID: 15840022] - Danielle G Souza, Riccardo Bertini, Angelica T Vieira, Fernando Q Cunha, Steve Poole, Marcello Allegretti, Francesco Colotta, Mauro M Teixeira. Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury.
British journal of pharmacology.
2004 Sep; 143(1):132-42. doi:
10.1038/sj.bjp.0705862. [PMID: 15302676]