Sodium benzofuran isophthalate (BioDeep_00000183190)

   

human metabolite blood metabolite


代谢物信息卡片


4-(6-{13-[2-(2,4-dicarboxyphenyl)-5-methoxy-1-benzofuran-6-yl]-1,4,10-trioxa-7,13-diazacyclopentadecan-7-yl}-5-methoxy-1-benzofuran-2-yl)benzene-1,3-dicarboxylic acid

化学式: C44H42N2O15 (838.2585)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 25%

分子结构信息

SMILES: COC1=C(C=C2C(=C1)C=C(O2)C3=C(C=C(C=C3)C(=O)O)C(=O)O)N4CCOCCN(CCOCCOCC4)C5=C(C=C6C=C(OC6=C5)C7=C(C=C(C=C7)C(=O)O)C(=O)O)OC
InChI: InChI=1S/C44H42N2O15/c1-55-39-21-27-19-37(29-5-3-25(41(47)48)17-31(29)43(51)52)60-35(27)23-33(39)45-7-11-57-12-8-46(10-14-59-16-15-58-13-9-45)34-24-36-28(22-40(34)56-2)20-38(61-36)30-6-4-26(42(49)50)18-32(30)44(53)54/h3-6,17-24H,7-16H2,1-2H3,(H,47,48)(H,49,50)(H,51,52)(H,53,54)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

8 个代谢物同义名

4-(6-{13-[2-(2,4-dicarboxyphenyl)-5-methoxy-1-benzofuran-6-yl]-1,4,10-trioxa-7,13-diazacyclopentadecan-7-yl}-5-methoxy-1-benzofuran-2-yl)benzene-1,3-dicarboxylic acid; 4,4-[1,4,10-Trioxa-7,13-diazacyclopentadecane-7,13-diylbis(5-methoxy-1-benzofuran-6,2-diyl)]diisophthalic acid; 4,4-[1,4,10-Trioxa-7,13-diazacyclopentadecane-7,13-diylbis(5-methoxy-1-benzofuran-6,2-diyl)]diisophthalate; Sodium-binding benzofuran isophthalic acid; Sodium-binding benzofuran isophthalate; Sodium benzofuran isophthalic acid; Sodium benzofuran isophthalate; SBFI



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Matthew J Jones, Taygun C Uzuneser, Timothy Clement, Hehe Wang, Iwao Ojima, Walter J Rushlow, Steven R Laviolette. Inhibition of fatty acid binding protein-5 in the basolateral amygdala induces anxiolytic effects and accelerates fear memory extinction. Psychopharmacology. 2023 Sep; ?(?):. doi: 10.1007/s00213-023-06468-7. [PMID: 37747506]
  • Taygun C Uzuneser, Hanna J Szkudlarek, Matthew J Jones, Mina G Nashed, Timothy Clement, Hehe Wang, Iwao Ojima, Walter J Rushlow, Steven R Laviolette. Identification of a novel fatty acid binding protein-5-CB2 receptor-dependent mechanism regulating anxiety behaviors in the prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). 2022 Jun; ?(?):. doi: 10.1093/cercor/bhac220. [PMID: 35650684]
  • Veena S Anil, P G Kavitha, Sam Kuruvilla, Pavan Kumar, M K Mathew. Measurements of cytosolic ion concentrations in live cells. Methods in molecular biology (Clifton, N.J.). 2013; 953(?):233-41. doi: 10.1007/978-1-62703-152-3_15. [PMID: 23073887]
  • Md Abdul Kader, Sylvia Lindberg. Uptake of sodium in protoplasts of salt-sensitive and salt-tolerant cultivars of rice, Oryza sativa L. determined by the fluorescent dye SBFI. Journal of experimental botany. 2005 Dec; 56(422):3149-58. doi: 10.1093/jxb/eri312. [PMID: 16275670]
  • Claudio D'Onofrio, Abdul Kader, Sylvia Lindberg. Uptake of sodium in quince, sugar beet, and wheat protoplasts determined by the fluorescent sodium-binding dye benzofuran isophthalate. Journal of plant physiology. 2005 Apr; 162(4):421-8. doi: 10.1016/j.jplph.2004.07.017. [PMID: 15900884]
  • János Peti-Peterdi, Zsuzsa Bebok, Jean-Yves Lapointe, P Darwin Bell. Novel regulation of cell [Na(+)] in macula densa cells: apical Na(+) recycling by H-K-ATPase. American journal of physiology. Renal physiology. 2002 Feb; 282(2):F324-9. doi: 10.1152/ajprenal.00251.2001. [PMID: 11788447]
  • Elfrida R Grant, Adrienne E Dubin, Sui-Po Zhang, Robert A Zivin, Zhong Zhong. Simultaneous intracellular calcium and sodium flux imaging in human vanilloid receptor 1 (VR1)-transfected human embryonic kidney cells: a method to resolve ionic dependence of VR1-mediated cell death. The Journal of pharmacology and experimental therapeutics. 2002 Jan; 300(1):9-17. doi: 10.1124/jpet.300.1.9. [PMID: 11752091]
  • R M Touyz, C Mercure, T L Reudelhuber. Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms. The Journal of biological chemistry. 2001 Apr; 276(17):13657-63. doi: 10.1074/jbc.m008101200. [PMID: 11278387]
  • I B Cheglakov, P V Avdonin. [Calcium antagonists nicardipine and verapamil suppress Ca(2+) entry and activate Na(+) entry into platelets]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2000 Sep; 86(9):1109-17. doi: . [PMID: 11081217]
  • S Despa, P Steels, M Ameloot. Fluorescence lifetime microscopy of the sodium indicator sodium-binding benzofuran isophthalate in HeLa cells. Analytical biochemistry. 2000 May; 280(2):227-41. doi: 10.1006/abio.2000.4505. [PMID: 10790305]
  • P S Liu, M K Lin, H L Hsieh. Dehydroepiandrosterone sulfate inhibition of catecholamine secretion from bovine adrenal chromaffin cells. Neuroscience letters. 1996 Feb; 204(3):181-4. doi: 10.1016/0304-3940(96)12350-8. [PMID: 8938260]
  • A M Reilly, P J Harris, D A Williams. Biphasic effect of angiotensin II on intracellular sodium concentration in rat proximal tubules. The American journal of physiology. 1995 Sep; 269(3 Pt 2):F374-80. doi: 10.1152/ajprenal.1995.269.3.f374. [PMID: 7573486]
  • P J Harris. Angiotensin II and atrial natriuretic factor: cellular mechanisms in mammalian proximal tubule. Experimental nephrology. 1994 Mar; 2(2):105. doi: NULL. [PMID: 8082001]
  • Z Deri, V Adam-Vizi. Detection of intracellular free Na+ concentration of synaptosomes by a fluorescent indicator, Na(+)-binding benzofuran isophthalate: the effect of veratridine, ouabain, and alpha-latrotoxin. Journal of neurochemistry. 1993 Sep; 61(3):818-25. doi: 10.1111/j.1471-4159.1993.tb03592.x. [PMID: 8360686]
  • P Donoso, J G Mill, S C O'Neill, D A Eisner. Fluorescence measurements of cytoplasmic and mitochondrial sodium concentration in rat ventricular myocytes. The Journal of physiology. 1992 Mar; 448(?):493-509. doi: 10.1113/jphysiol.1992.sp019053. [PMID: 1593474]
  • S O Sage, T J Rink, M P Mahaut-Smith. Resting and ADP-evoked changes in cytosolic free sodium concentration in human platelets loaded with the indicator SBFI. The Journal of physiology. 1991 Sep; 441(?):559-73. doi: 10.1113/jphysiol.1991.sp018767. [PMID: 1816386]
  • A T Harootunian, J P Kao, B K Eckert, R Y Tsien. Fluorescence ratio imaging of cytosolic free Na+ in individual fibroblasts and lymphocytes. The Journal of biological chemistry. 1989 Nov; 264(32):19458-67. doi: NULL. [PMID: 2478559]